Cheap flights from Philadelphia to Des Moines from $43

If you’re not able to fly to Des Moines in July, then June is your next best option. Flight prices from Philadelphia to Des Moines during June average around $216.

The cheapest day to depart from Philadelphia to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $126. Flights from Philadelphia to Des Moines on a Tuesday will generally be more expensive and average around $468. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Philadelphia to Des Moines in the afternoon for as low as $83. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $383. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Philadelphia to Des Moines for the best Philadelphia - Des Moines flight prices

You are more likely to see cheaper flights to Des Moines from Philadelphia when booking weeks ahead of your departure date. In general, you can expect to find flights to Des Moines for around $351 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Des Moines from Philadelphia for as low as $112 on momondo.

There are 2 cabin classes available to choose from on Philadelphia to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Philadelphia to Des Moines.

As of September 2026, prices for Philadelphia to Des Moines flights are approximately 50% cheaper when compared to flights at the same time last year.

Southwest is the most popular carrier operating from Philadelphia to Des Moines

American Airlines, Delta and Allegiant Air are the top three most popular airlines that fly to Des Moines from Philadelphia according to our data. American Airlines is the first choice among our users, with 32% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 5 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

The number of flights available between Philadelphia and Des Moines is 3 per day as of September 2026. The most frequent departure time is 7:00PM, with 66% of daily flights leaving in the evening.

The number of flights available between Philadelphia and Des Moines is 23 per week as of September 2026. The most frequent departure day is Thu, with 17% of weekly flights leaving on this day.