Cheap flights from Panama City to the United States from $221

In general, May is the cheapest month to fly from Panama City to United States. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $488. If you aren’t able to travel during the month of May, then book flights to United States from Panama City during July instead. Flights to United States in July, while not as cheap as those in May, still average around $488.

According to our data, Saturday is the cheapest day to fly to United States from Panama City. The lowest ticket price found for a Saturday departure recently was $599. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $707. These prices are subject to change though, so be sure to set up a Price Alert for flights to United States.

The cheapest time of day to fly to United States is in the afternoon when flights can be purchased for as low as $566. Try not to purchase tickets in the morning because they tend to be around $687. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Panama City Tocumen Intl to Miami for the best Panama City Tocumen Intl - United States flight prices

You are more likely to see cheaper flights to United States from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to United States for around $574 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to United States from Panama City for as low as $425 on momondo.

There are 4 cabin classes available to choose from on Panama City Tocumen Intl to United States flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Avianca and Aeromexico are the most popular carriers operating from Panama City Tocumen Intl to United States

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to United States from Panama City according to our data. Copa Airlines is the first choice among our users, with 70% of people opting to fly with this airline when traveling to United States. Keep in mind that there are 5 different airlines that fly to United States on a routine basis, so you have a few additional options to choose from.

Historically, on average around 5% of flights between Panama City and United States have experienced a delay on any given week. The average delay length over the past 12 months has been 130 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Thursday is statistically the day of the week which experiences the fewest number of delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 3% of their flights experiencing any sort of delay.

51 flights are operational daily from Panama City to United States as of February 2026. The most popular departure time for this route is 6:00PM, with 42% of flights per day taking off at noon.

The number of flights available between Panama City and United States is 361 per week as of February 2026. The most frequent departure day is Tue, with 18% of weekly flights leaving on this day.