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Cheap flights from Orlando Airport to Florence from $316

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Orlando Airport to Florence departing on 9/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

American Airlines Logo
6:10 am - 5:12 pmMCO-FLO
11h 02m2 stops
American Airlines Logo
6:14 am - 7:44 pmFLO-MCO
13h 30m2 stops
$316American Airlines
Find Deal
mié., sep. 24 - mié., oct. 1
American Airlines Logo
10:20 am - 5:12 pmMCO-FLO
6h 52m1 stop
American Airlines Logo
6:14 am - 10:27 amFLO-MCO
4h 13m1 stop
$387American Airlines
Find Deal
mié., sep. 24 - mié., oct. 1
American Airlines Logo
12:47 pm - 5:12 pmMCO-FLO
4h 25m1 stop
American Airlines Logo
6:14 am - 4:50 pmFLO-MCO
10h 36m2 stops
$392American Airlines
Find Deal
mié., sep. 24 - mié., oct. 1
American Airlines Logo
6:38 pm - 11:40 pmMCO-FLO
5h 02m1 stop
American Airlines Logo
6:55 am - 10:46 amFLO-MCO
3h 51m1 stop
$411American Airlines
Find Deal
mié., dic. 3 - lun., dic. 8
American Airlines Logo
6:32 am - 2:08 pmMCO-FLO
7h 36m2 stops
American Airlines Logo
2:29 pm - 6:43 pmFLO-MCO
4h 14m1 stop
$416American Airlines
Find Deal
mié., dic. 3 - lun., dic. 8
American Airlines Logo
7:56 am - 2:08 pmMCO-FLO
6h 12m2 stops
American Airlines Logo
6:55 am - 1:17 pmFLO-MCO
6h 22m2 stops
$421American Airlines
Find Deal
mié., dic. 3 - lun., dic. 8
American Airlines Logo
6:30 pm - 11:02 pmMCO-FLO
4h 32m1 stop
American Airlines Logo
5:09 am - 8:50 amFLO-MCO
3h 41m1 stop
$472American Airlines
Find Deal
mié., ago. 13 - dom., ago. 17
American Airlines Logo
6:10 am - 3:04 pmMCO-FLO
8h 54m2 stops
American Airlines Logo
2:34 pm - 7:46 pmFLO-MCO
5h 12m1 stop
$477American Airlines
Find Deal
mié., ago. 13 - dom., ago. 17
American Airlines Logo
6:10 am - 3:04 pmMCO-FLO
8h 54m2 stops
American Airlines Logo
5:09 am - 2:00 pmFLO-MCO
8h 51m2 stops
$482American Airlines
Find Deal
mié., ago. 13 - dom., ago. 17
American Airlines Logo
5:00 am - 10:45 amMCO-FLO
5h 45m1 stop
American Airlines Logo
6:55 am - 12:46 pmFLO-MCO
5h 51m1 stop
$708American Airlines
Find Deal
mar., dic. 2 - vie., dic. 5

American Airlines flights from Orlando Airport to Florence, South Carolina

Our best American Airlines deals on Orlando Airport to Florence, South Carolina flight tickets
American Airlines
Sep 24
MCO6:10 amOrlando
11h 02m
2 stops
FLO5:12 pmFlorence
Oct 1
FLO6:14 amFlorence
13h 30m
2 stops
MCO7:44 pmOrlando
$316
Find similar
American Airlines
Sep 24
MCO10:20 amOrlando
6h 52m
1 stop
FLO5:12 pmFlorence
Oct 1
FLO6:14 amFlorence
4h 13m
1 stop
MCO10:27 amOrlando
$387
Find similar
American Airlines
Sep 24
MCO12:47 pmOrlando
4h 25m
1 stop
FLO5:12 pmFlorence
Oct 1
FLO6:14 amFlorence
10h 36m
2 stops
MCO4:50 pmOrlando
$392
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Orlando Airport to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated julio 31, 2025.
Use the filters below to find and compare flights from Orlando Airport to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

mié. 9/24

6:10 am-5:12 pm

2 stops11h 02m

Florence

mié. 10/1

6:14 am-7:44 pm

2 stops13h 30m

$316

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

mié. 9/24

10:20 am-5:12 pm

1 stop6h 52m

Florence

mié. 10/1

6:14 am-10:27 am

1 stop4h 13m

$387

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

mié. 9/24

12:47 pm-5:12 pm

1 stop4h 25m

Florence

mié. 10/1

6:14 am-4:50 pm

2 stops10h 36m

$392

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

mié. 12/3

6:38 pm-11:40 pm

1 stop5h 02m

Florence

lun. 12/8

6:55 am-10:46 am

1 stop3h 51m

$411

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

mié. 12/3

6:32 am-2:08 pm

2 stops7h 36m

Florence

lun. 12/8

2:29 pm-6:43 pm

1 stop4h 14m

$416

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

mié. 12/3

7:56 am-2:08 pm

2 stops6h 12m

Florence

lun. 12/8

6:55 am-1:17 pm

2 stops6h 22m

$421

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

mié. 8/13

6:30 pm-11:02 pm

1 stop4h 32m

Florence

dom. 8/17

5:09 am-8:50 am

1 stop3h 41m

$472

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

mié. 8/13

6:10 am-3:04 pm

2 stops8h 54m

Florence

dom. 8/17

2:34 pm-7:46 pm

1 stop5h 12m

$477

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

mié. 8/13

6:10 am-3:04 pm

2 stops8h 54m

Florence

dom. 8/17

5:09 am-2:00 pm

2 stops8h 51m

$482

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

mar. 12/2

5:00 am-10:45 am

1 stop5h 45m

Florence

vie. 12/5

6:55 am-12:46 pm

1 stop5h 51m

$708

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Orlando Airport to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is in the morning. momondo users have found flights departing from Orlando Airport to Florence, South Carolina in the morning for as low as $462. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the afternoon is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $590 per ticket.

When to book flights from Orlando Airport to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando Airport to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando Airport to Florence, South Carolina (MCO to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando Airport to Florence, South Carolina

Best Price Found

$316

Fastest flight time

4h 25m

Direct flights

None

Airports in Florence, South Carolina

1 airport
The best flight deal from Orlando Airport to Florence, South Carolina found on momondo in the last 72 hours is $316
The fastest flight from Orlando Airport to Florence, South Carolina takes 4h 25m
There are no direct flights from Orlando Airport to Florence, South Carolina. Popular non-direct route for this connection is Orlando Airport - Florence Airport.
There is 1 airport near Florence, South Carolina: Florence (FLO)
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  • How far is Orlando to Florence by plane?

    Florence is 408.3 mi away from Orlando. By plane, this route typically takes 4h 25m.

  • When did momondo last update prices for flights from Orlando Airport to Florence Airport?

    Prices for flights from Orlando Airport to Florence Airport refresh daily.

  • How old do you have to be to fly from Orlando Airport to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Orlando Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Florence?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Orlando to Florence for you.

Can I find flights from Orlando to Florence with flexible booking policies on momondo?

Yes. All flights to Florence from Orlando on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Orlando to Florence?

momondo helps you find the best flight between Orlando and Florence by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Orlando to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from Orlando. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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