Cheap flights from Oregon to St. Louis from $136

In general, January is the cheapest month to fly from Oregon to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $345. The month of May is another great option to travel to St. Louis, with average flight prices from Oregon averaging around $351.

The cheapest day to depart on your flight to St. Louis is on a Tuesday when prices can be found for as low as $377. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $457. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

Fly from Portland to Lambert-St Louis for the best Oregon - Lambert-St Louis flight prices

You are more likely to see cheaper flights to St. Louis from Oregon when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $377 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Oregon for as low as $240 on momondo.

There are 3 cabin classes available to choose from on Oregon to St. Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 28% on your flight if you consider stops on a Oregon to St. Louis flight.

Southwest, United Airlines, and Delta are the most popular carriers operating from Oregon to Lambert-St Louis

Alaska Airlines, Delta and United Airlines are the top three most popular airlines that fly to St. Louis from Oregon according to our data. Alaska Airlines is the first choice among our users, with 32% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 6 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

As of September 2026, 2 flights take off from Oregon and land in St. Louis each week. The most common flight departure day for this route is Thu, with 50% of weekly flights taking off on this day.

Flight times from Oregon to St. Louis vary, but if you’re flying out of Portland and flying into St. Louis (one of the most popular routes), then the duration is 3h 45m on average. Another popular route from Oregon to St. Louis is flying from Redmond to St. Louis, which will take roughly 5h 13m. Keep in mind that layovers or delays could extend your travel time.