Cheap flights from Ohio to South Carolina from $28

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to South Carolina departing on 4/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Ohio to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
3:00 pm - 4:44 pm
CLE
-
MYR
1h 44mnonstop
Frontier Logo
5:29 pm - 7:22 pm
MYR
-
CLE
1h 53mnonstop
$67Frontier
Sun, Apr 26 - Thu, Apr 30
Frontier Logo
3:00 pm - 4:44 pm
CLE
-
MYR
1h 44mnonstop
Frontier Logo
5:29 pm - 7:22 pm
MYR
-
CLE
1h 53mnonstop
$68Frontier
Sun, Apr 19 - Thu, Apr 23
Breeze Airways Logo
1:19 pm - 2:59 pm
CAK
-
MYR
1h 40mnonstop
Breeze Airways Logo
9:45 am - 11:28 am
MYR
-
CAK
1h 43mnonstop
$97Breeze Airways
Wed, Aug 19 - Mon, Aug 24
Breeze Airways Logo
1:19 pm - 2:59 pm
CAK
-
MYR
1h 40mnonstop
Breeze Airways Logo
2:30 pm - 4:22 pm
MYR
-
CAK
1h 52mnonstop
$99Breeze Airways
Wed, Sep 2 - Sat, Sep 12
Allegiant Air Logo
2:38 pm - 4:11 pm
CAK
-
MYR
1h 33mnonstop
Allegiant Air Logo
5:01 pm - 6:42 pm
MYR
-
CAK
1h 41mnonstop
$101Allegiant Air
Thu, May 7 - Thu, May 14
Allegiant Air Logo
2:38 pm - 4:11 pm
CAK
-
MYR
1h 33mnonstop
Allegiant Air Logo
5:01 pm - 6:42 pm
MYR
-
CAK
1h 41mnonstop
$102Allegiant Air
Thu, May 7 - Sun, May 10
Spirit Airlines Logo
11:52 am - 1:18 pm
PIT
-
MYR
1h 26mnonstop
Spirit Airlines Logo
9:18 am - 10:47 am
MYR
-
PIT
1h 29mnonstop
$113Spirit Airlines
Sun, Apr 19 - Thu, Apr 30
Spirit Airlines Logo
11:52 am - 1:18 pm
PIT
-
MYR
1h 26mnonstop
Spirit Airlines Logo
9:18 am - 10:47 am
MYR
-
PIT
1h 29mnonstop
$115Spirit Airlines
Sun, Apr 19 - Sun, Apr 26
Delta Logo
7:00 am - 9:48 pm
DTW
-
SAV
14h 48m
1 stop
Delta Logo
6:33 pm - 8:45 pm
SAV
-
DTW
2h 12mnonstop
$326Delta
Tue, Apr 28 - Thu, May 7
Delta Logo
12:15 pm - 11:02 pm
DTW
-
SAV
10h 47m
1 stop
Delta Logo
7:00 am - 7:05 pm
SAV
-
DTW
12h 05m
1 stop
$328Delta
Mon, Apr 27 - Tue, May 5

Spirit Airlines flights from Ohio to South Carolina

Our best Spirit Airlines deals on Ohio to South Carolina flight tickets
Spirit Airlines
Apr 19
PIT11:52 amPittsburgh
1h 26m
MYR1:18 pmMyrtle Beach Intl
Apr 30
MYR9:18 amMyrtle Beach Intl
1h 29m
PIT10:47 amPittsburgh
$113
Spirit Airlines
Apr 19
PIT11:52 amPittsburgh
1h 26m
MYR1:18 pmMyrtle Beach Intl
Apr 26
MYR9:18 amMyrtle Beach Intl
1h 29m
PIT10:47 amPittsburgh
$115
Spirit Airlines
Apr 19
PIT6:15 pmPittsburgh
5h 14m
1 stop
MYR11:29 pmMyrtle Beach Intl
Apr 25
MYR3:42 pmMyrtle Beach Intl
1h 29m
PIT5:11 pmPittsburgh
$116

Frontier flights from Ohio to South Carolina

Our best Frontier deals on Ohio to South Carolina flight tickets
Frontier
Apr 26
CLE3:00 pmCleveland Hopkins Intl
1h 44m
MYR4:44 pmMyrtle Beach Intl
Apr 30
MYR5:29 pmMyrtle Beach Intl
1h 53m
CLE7:22 pmCleveland Hopkins Intl
$67
Frontier
Apr 19
CLE3:00 pmCleveland Hopkins Intl
1h 44m
MYR4:44 pmMyrtle Beach Intl
Apr 23
MYR5:29 pmMyrtle Beach Intl
1h 53m
CLE7:22 pmCleveland Hopkins Intl
$68
Frontier
Apr 19
CLE3:00 pmCleveland Hopkins Intl
1h 44m
MYR4:44 pmMyrtle Beach Intl
Apr 23
MYR5:29 pmMyrtle Beach Intl
1h 53m
CLE7:22 pmCleveland Hopkins Intl
$74

momondo Fare Finder

 
Customize your flight search to find flights from Ohio to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Ohio to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandMyrtle Beach

CLE - MYR

CLEMYR

Cleveland Hopkins Intl

Sun 4/26

3:00 pm-4:44 pm

Nonstop1h 44m

Myrtle Beach Intl

Thu 4/30

5:29 pm-7:22 pm

Nonstop1h 53m

$67

ClevelandMyrtle Beach

CLE - MYR

CLEMYR

Cleveland Hopkins Intl

Sun 4/19

3:00 pm-4:44 pm

Nonstop1h 44m

Myrtle Beach Intl

Thu 4/23

5:29 pm-7:22 pm

Nonstop1h 53m

$68

AkronMyrtle Beach

CAK - MYR

CAKMYR

Akron/Canton

Wed 8/19

1:19 pm-2:59 pm

Nonstop1h 40m

Myrtle Beach Intl

Mon 8/24

9:45 am-11:28 am

Nonstop1h 43m

$97

AkronMyrtle Beach

CAK - MYR

CAKMYR

Akron/Canton

Wed 9/2

1:19 pm-2:59 pm

Nonstop1h 40m

Myrtle Beach Intl

Sat 9/12

2:30 pm-4:22 pm

Nonstop1h 52m

$99

AkronMyrtle Beach

CAK - MYR

CAKMYR

Akron/Canton

Thu 5/7

2:38 pm-4:11 pm

Nonstop1h 33m

Myrtle Beach Intl

Thu 5/14

5:01 pm-6:42 pm

Nonstop1h 41m

$101

AkronMyrtle Beach

CAK - MYR

CAKMYR

Akron/Canton

Thu 5/7

2:38 pm-4:11 pm

Nonstop1h 33m

Myrtle Beach Intl

Sun 5/10

5:01 pm-6:42 pm

Nonstop1h 41m

$102
Quickest round-trip

PittsburghMyrtle Beach

PIT - MYR

PITMYR

Pittsburgh

Sun 4/19

11:52 am-1:18 pm

Nonstop1h 26m

Myrtle Beach Intl

Thu 4/30

9:18 am-10:47 am

Nonstop1h 29m

$113

PittsburghMyrtle Beach

PIT - MYR

PITMYR

Pittsburgh

Sun 4/19

11:52 am-1:18 pm

Nonstop1h 26m

Myrtle Beach Intl

Sun 4/26

9:18 am-10:47 am

Nonstop1h 29m

$115

DetroitSavannah

DTW - SAV

DTWSAV

Detroit Metropolitan Wayne County

Tue 4/28

7:00 am-9:48 pm

1 stop14h 48m

Savannah/Hilton Head

Thu 5/7

6:33 pm-8:45 pm

Nonstop2h 12m

$326

DetroitSavannah

DTW - SAV

DTWSAV

Detroit Metropolitan Wayne County

Mon 4/27

12:15 pm-11:02 pm

1 stop10h 47m

Savannah/Hilton Head

Tue 5/5

7:00 am-7:05 pm

1 stop12h 05m

$328

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Ohio to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Ohio is in September. Flight prices, which tend to average around $296, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Ohio during November instead. Flights to South Carolina in November, while not as cheap as those in September, still average around $301.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Monday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $81. The most expensive day to fly to South Carolina is Wednesday, with ticket prices averaging around $181.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Ohio to South Carolina flights are usually those with departure times at noon. Our users have found flights to South Carolina at noon for as low as $128. Try not to purchase tickets in the afternoon because they tend to be around $169. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Ohio to South Carolina flight route?

Fly from Columbus Rickenbacker to Charleston for the best Ohio - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Ohio when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $353 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Ohio for as low as $241 on momondo.

What cabin class options are available on Ohio to South Carolina flights?

There are 2 cabin classes available to choose from on Ohio to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Ohio to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Ohio to South Carolina.

Cheap Ohio to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to South Carolina

Best Price Found

$70

Fastest flight time

1h 10m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun

Airports in South Carolina

57 airports
The best one-way flight to South Carolina from Ohio in the past 72 hours is $70. The best round-trip flight deal from Ohio to South Carolina found on momondo in the last 72 hours is $114.
The fastest flight from Ohio to South Carolina takes 1h 10m
Direct flights go from Ohio to South Carolina on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. Airlines offering direct flights are: Breeze Airways and Allegiant Air.
There are 57 airports in South Carolina. From Ohio there are direct flights to Myrtle Beach Intl (MYR), Charlotte Douglas (CLT).
  • When did momondo last update prices for flights from Ohio to South Carolina?

    Prices for flights from Ohio to South Carolina are updated daily.

  • How many operators does momondo search for flights from Ohio to South Carolina?

  • How old do you have to be to fly from Ohio to South Carolina?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Ohio to South Carolina?

Best airlines flying from Ohio to South Carolina

Compare and see reviews for airlines that fly from Ohio to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Breeze AirwaysPriceFrom $46Free CancellationRating
8.1
275 reviews
Search Breeze Airways flights
Allegiant AirPriceFrom $54Free CancellationRating
7.3
709 reviews
Search Allegiant Air flights
FrontierPriceFrom $57Free CancellationRating
5.7
3,005 reviews
Search Frontier flights
Spirit AirlinesPriceFrom $68Free CancellationRating
6.3
8,574 reviews
Search Spirit Airlines flights
DeltaPriceFrom $100Free CancellationRating
7.9
8,366 reviews
Search Delta flights
United AirlinesPriceFrom $128Free CancellationRating
7.4
9,534 reviews
Search United Airlines flights
American AirlinesPriceFrom $164Free CancellationRating
7.1
11,545 reviews
Search American Airlines flights
SouthwestPriceFrom $196Free CancellationRating
8.0
4,336 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Ohio to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Ohio to South Carolina with flexible booking policies on momondo?

Flights from Ohio to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Ohio to South Carolina?

Once all potential Ohio to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Ohio to South Carolina right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South Carolina from Ohio. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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1 adult
Fri 5/1
Fri 5/8

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Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo