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Cheap flights from Missouri to Illinois from $50

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Illinois departing on 9/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Missouri to Illinois

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:13 pm - 6:52 pmSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
1h 39mnonstop
American Airlines Logo
7:00 am - 8:24 amORD  Chicago O'Hare Intl-STL Lambert-St Louis
1h 24mnonstop
$117American Airlines
Sat, Sep 5 - Sun, Sep 6
American Airlines Logo
5:00 am - 6:24 amSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
1h 24mnonstop
American Airlines Logo
10:44 pm - 11:58 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
1h 14mnonstop
$117American Airlines
Sat, Sep 5 - Sat, Sep 5
United Airlines Logo
8:00 am - 9:34 amSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
1h 34mnonstop
United Airlines Logo
2:00 pm - 3:31 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
1h 31mnonstop
$117United Airlines
Sat, Sep 5 - Sat, Sep 5
United Airlines Logo
7:25 am - 9:01 amSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
1h 36mnonstop
United Airlines Logo
10:29 am - 12:02 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
1h 33mnonstop
$117United Airlines
Sat, Sep 5 - Sun, Sep 6
Southwest Logo
5:45 am - 6:50 amSTL  Lambert-St Louis-MDW Chicago Midway
1h 05mnonstop
Southwest Logo
8:10 am - 1:45 pmMDW  Chicago Midway-STL Lambert-St Louis
5h 35m1 stop Washington, D.C. Reagan-National
$127Southwest
Sat, Sep 5 - Sun, Sep 6
Southwest Logo
5:45 am - 6:50 amSTL  Lambert-St Louis-MDW Chicago Midway
1h 05mnonstop
Southwest Logo
8:10 am - 1:45 pmMDW  Chicago Midway-STL Lambert-St Louis
5h 35m1 stop Washington, D.C. Reagan-National
$127Southwest
Sat, Sep 5 - Sun, Sep 6
Frontier Logo
2:29 pm - 11:51 amSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
21h 22m1 stop Atlanta Hartsfield-Jackson
Frontier Logo
6:30 am - 7:17 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
12h 47m1 stop Denver Intl
$147Frontier
Mon, Sep 28 - Sat, Oct 3
Frontier Logo
10:35 am - 8:28 pmSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
9h 53m1 stop Atlanta Hartsfield-Jackson
Frontier Logo
6:05 am - 5:46 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
11h 41m1 stop Dallas/Fort Worth
$154Frontier
Thu, Oct 15 - Mon, Oct 19
Contour Logo
9:50 am - 11:45 amCGI  Cape Girardeau-ORD Chicago O'Hare Intl
1h 55mnonstop
Contour Logo
4:00 pm - 5:35 pmORD  Chicago O'Hare Intl-CGI Cape Girardeau
1h 35mnonstop
$159Contour
Mon, Aug 31 - Wed, Sep 2
Contour Logo
9:40 am - 11:35 amCGI  Cape Girardeau-ORD Chicago O'Hare Intl
1h 55mnonstop
Contour Logo
11:15 am - 12:50 pmORD  Chicago O'Hare Intl-CGI Cape Girardeau
1h 35mnonstop
$159Contour
Thu, Nov 26 - Mon, Nov 30

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American Airlines flights from Missouri to Illinois

Our best American Airlines deals on Missouri to Illinois flight tickets
American Airlines
Sep 5
STL5:00 amLambert-St Louis
1h 24m
ORD6:24 amChicago O'Hare Intl
Sep 6
ORD7:00 amChicago O'Hare Intl
1h 24m
STL8:24 amLambert-St Louis
$118
American Airlines
Sep 5
STL5:00 amLambert-St Louis
1h 24m
ORD6:24 amChicago O'Hare Intl
Sep 6
ORD7:00 amChicago O'Hare Intl
1h 24m
STL8:24 amLambert-St Louis
$187
American Airlines
Sep 21
STL5:00 amLambert-St Louis
1h 29m
ORD6:29 amChicago O'Hare Intl
Sep 24
ORD11:05 pmChicago O'Hare Intl
1h 22m
STL12:27 amLambert-St Louis
$220

Frontier flights from Missouri to Illinois

Our best Frontier deals on Missouri to Illinois flight tickets
Frontier
Sep 28
STL2:29 pmLambert-St Louis
21h 22m
1 stop
ORD11:51 amChicago O'Hare Intl
Oct 3
ORD6:30 amChicago O'Hare Intl
12h 47m
1 stop
STL7:17 pmLambert-St Louis
$147
Frontier
Oct 15
STL6:41 pmLambert-St Louis
5h 43m
1 stop
ORD12:24 amChicago O'Hare Intl
Oct 19
ORD6:05 amChicago O'Hare Intl
11h 41m
1 stop
STL5:46 pmLambert-St Louis
$154
Frontier
Oct 2
STL2:29 pmLambert-St Louis
27h 54m
1 stop
ORD6:23 pmChicago O'Hare Intl
Oct 5
ORD6:30 amChicago O'Hare Intl
12h 47m
1 stop
STL7:17 pmLambert-St Louis
$156

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from Missouri to Illinois that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisChicago

STL Lambert-St Louis - ORD Chicago O'Hare Intl

STLORD

Lambert-St Louis

Sat 9/5

5:13 pm-6:52 pm

Nonstop1h 39m

Chicago O'Hare Intl

Sun 9/6

7:00 am-8:24 am

Nonstop1h 24m

$117
Quickest round-trip

St. LouisChicago

STL Lambert-St Louis - ORD Chicago O'Hare Intl

STLORD

Lambert-St Louis

Sat 9/5

5:00 am-6:24 am

Nonstop1h 24m

Chicago O'Hare Intl

Sat 9/5

10:44 pm-11:58 pm

Nonstop1h 14m

$117

St. LouisChicago

STL Lambert-St Louis - ORD Chicago O'Hare Intl

STLORD

Lambert-St Louis

Sat 9/5

8:00 am-9:34 am

Nonstop1h 34m

Chicago O'Hare Intl

Sat 9/5

2:00 pm-3:31 pm

Nonstop1h 31m

$117

St. LouisChicago

STL Lambert-St Louis - ORD Chicago O'Hare Intl

STLORD

Lambert-St Louis

Sat 9/5

7:25 am-9:01 am

Nonstop1h 36m

Chicago O'Hare Intl

Sun 9/6

10:29 am-12:02 pm

Nonstop1h 33m

$117

St. LouisChicago

STL Lambert-St Louis - MDW Chicago Midway

STLMDW

Lambert-St Louis

Sat 9/5

5:45 am-6:50 am

Nonstop1h 05m

Chicago Midway

Sun 9/6

8:10 am-1:45 pm

1 stop5h 35m

$127

St. LouisChicago

STL Lambert-St Louis - MDW Chicago Midway

STLMDW

Lambert-St Louis

Sat 9/5

5:45 am-6:50 am

Nonstop1h 05m

Chicago Midway

Sun 9/6

8:10 am-1:45 pm

1 stop5h 35m

$127

St. LouisChicago

STL Lambert-St Louis - ORD Chicago O'Hare Intl

STLORD

Lambert-St Louis

Mon 9/28

2:29 pm-11:51 am

1 stop21h 22m

Chicago O'Hare Intl

Sat 10/3

6:30 am-7:17 pm

1 stop12h 47m

$147

St. LouisChicago

STL Lambert-St Louis - ORD Chicago O'Hare Intl

STLORD

Lambert-St Louis

Thu 10/15

10:35 am-8:28 pm

1 stop9h 53m

Chicago O'Hare Intl

Mon 10/19

6:05 am-5:46 pm

1 stop11h 41m

$154

Cape GirardeauChicago

CGI Cape Girardeau - ORD Chicago O'Hare Intl

CGIORD

Cape Girardeau

Mon 8/31

9:50 am-11:45 am

Nonstop1h 55m

Chicago O'Hare Intl

Wed 9/2

4:00 pm-5:35 pm

Nonstop1h 35m

$159

Cape GirardeauChicago

CGI Cape Girardeau - ORD Chicago O'Hare Intl

CGIORD

Cape Girardeau

Thu 11/26

9:40 am-11:35 am

Nonstop1h 55m

Chicago O'Hare Intl

Mon 11/30

11:15 am-12:50 pm

Nonstop1h 35m

$159

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Illinois from

How to get the cheapest flight ticket from Missouri to Illinois

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Illinois?

The cheapest month to fly to Illinois from Missouri is in December. Flight prices, which tend to average around $279, are often lower during this time because this is during the off-season. If you aren’t able to travel to Illinois during the month of December, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $297.

What is the cheapest day to depart on your flight to Illinois?

The cheapest day to depart from Missouri to Illinois is on a Friday when prices can be found for as low as $620. Flights from Missouri to Illinois on a Monday will generally be more expensive and average around $800. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Illinois?

Our most recent data shows that the best time of day to fly to Illinois is in the morning. Flights from Missouri to Illinois during this time can be as low as $581. Flights at noon are often more expensive with an average ticket price of $1,130.

What is the cheapest Missouri to Illinois flight route?

Fly from Lambert-St Louis to Chicago Midway for the best Missouri - Illinois flight prices

How far in advance should I book a flight from Missouri to Illinois?

You are more likely to see cheaper flights to Illinois from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Illinois for around $345 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Illinois from Missouri for as low as $97 on momondo.

What cabin class options are available on Missouri to Illinois flights?

There are 4 cabin classes available to choose from on Missouri to Illinois flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Missouri to Illinois flights?

No. A direct flight is the cheapest option for a flight between Missouri to Illinois.

Cheap Missouri to Illinois flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Illinois

Best Price Found

$69

Fastest flight time

1h 00m

Direct flights

Every day

Airports in Illinois

98 airports
The best one-way flight to Illinois from Missouri in the past 72 hours is $69. The best round-trip flight deal from Missouri to Illinois found on momondo in the last 72 hours is $138.
The fastest flight from Missouri to Illinois takes 1h 00m
Direct flights go from Missouri to Illinois every day.
There are 98 airports in Illinois. From Missouri there are direct flights to Chicago Midway (MDW), Lambert-St Louis (STL).
Search flight deals

Frequently asked questions about flying from Missouri to Illinois

  • When did momondo last update prices for flights from Missouri to Illinois?

    Prices for flights from Missouri to Illinois refresh daily.

  • How many operators does momondo search for flights from Missouri to Illinois?

  • How old do you have to be to fly from Missouri to Illinois?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Illinois.

  • What documentation or ID do you need to fly to Illinois?

    The required travel and health documents for your Illinois trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Illinois. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Missouri to Illinois?

Best airlines flying from Missouri to Illinois

Compare and see reviews for airlines that fly from Missouri to Illinois with momondo
Airline
Rating
Free Cancellation
Price
ContourPriceFrom $62Free CancellationRating
7.5
43 reviews
Search Contour flights
American AirlinesPriceFrom $97Free CancellationRating
7.1
11,923 reviews
Search American Airlines flights
United AirlinesPriceFrom $117Free CancellationRating
7.4
10,112 reviews
Search United Airlines flights
FrontierPriceFrom $158Free CancellationRating
5.6
2,698 reviews
Search Frontier flights
SouthwestPriceFrom $181Free CancellationRating
8.0
4,219 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Illinois?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Illinois from Missouri.

Can I find flights from Missouri to Illinois with flexible booking policies on momondo?

Yes. All flights to Illinois from Missouri on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Missouri to Illinois?

momondo helps you find the best flight between Missouri and Illinois by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Illinois right now. Can momondo alert me if prices change?

Price alerts on flights to Illinois from Missouri are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Illinois trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to Illinois

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