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Cheap flights from Missouri to Illinois from $48

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Illinois departing on 4/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Missouri to Illinois

Cheap round-trip flights

Enter your travel dates to find the best prices.
Contour Logo
9:25 am - 11:10 am
CGI
-
ORD
1h 45mnonstop
Contour Logo
11:50 am - 1:30 pm
ORD
-
CGI
1h 40mnonstop
$123Contour
Thu, Mar 12 - Sat, Mar 14
Contour Logo
9:25 am - 11:10 am
CGI
-
ORD
1h 45mnonstop
Contour Logo
11:50 am - 1:30 pm
ORD
-
CGI
1h 40mnonstop
$125Contour
Thu, Mar 12 - Mon, Mar 16
United Airlines Logo
3:23 pm - 4:56 pm
COU
-
ORD
1h 33mnonstop
United Airlines Logo
1:00 pm - 2:32 pm
ORD
-
COU
1h 32mnonstop
$179United Airlines
Mon, Apr 27 - Sat, May 16
American Airlines Logo
5:19 am - 7:07 am
SGF
-
ORD
1h 48mnonstop
American Airlines Logo
3:43 pm - 5:35 pm
ORD
-
SGF
1h 52mnonstop
$189American Airlines
Thu, Apr 9 - Sun, Apr 12
United Airlines Logo
11:23 am - 1:05 pm
COU
-
ORD
1h 42mnonstop
United Airlines Logo
9:15 am - 10:48 am
ORD
-
COU
1h 33mnonstop
$192United Airlines
Thu, May 21 - Sun, May 24
Frontier Logo
2:15 pm - 7:21 pm
MCI
-
STL
5h 06m
1 stop
Frontier Logo
8:06 pm - 1:30 pm
STL
-
MCI
17h 24m
1 stop
$192Frontier
Fri, Apr 24 - Sun, Apr 26
American Airlines Logo
6:30 pm - 8:05 pm
COU
-
ORD
1h 35mnonstop
American Airlines Logo
6:50 pm - 8:19 pm
ORD
-
COU
1h 29mnonstop
$194American Airlines
Fri, Mar 13 - Fri, Mar 20
Southwest Logo
12:25 pm - 4:55 pm
STL
-
MDW
4h 30m
1 stop
Southwest Logo
9:15 am - 10:30 am
MDW
-
STL
1h 15mnonstop
$197Southwest
Sat, Apr 11 - Sat, Apr 18
Southwest Logo
7:20 am - 8:30 am
STL
-
MDW
1h 10mnonstop
Southwest Logo
3:50 pm - 8:55 pm
MDW
-
STL
5h 05m
1 stop
$198Southwest
Thu, Apr 9 - Mon, Apr 13
Frontier Logo
11:27 am - 8:23 am
STL
-
ORD
20h 56m
1 stop
Frontier Logo
8:55 pm - 9:48 am
ORD
-
STL
12h 53m
2 stops
$200Frontier
Tue, Mar 24 - Tue, Mar 31

Contour flights from Missouri to Illinois

Our best Contour deals on Missouri to Illinois flight tickets
Contour
Mar 12
CGI9:25 amCape Girardeau
1h 45m
ORD11:10 amChicago O'Hare Intl
Mar 14
ORD11:50 amChicago O'Hare Intl
1h 40m
CGI1:30 pmCape Girardeau
$123
Contour
Mar 12
CGI9:25 amCape Girardeau
1h 45m
ORD11:10 amChicago O'Hare Intl
Mar 16
ORD11:50 amChicago O'Hare Intl
1h 40m
CGI1:30 pmCape Girardeau
$125
Contour
May 29
CGI9:45 amCape Girardeau
1h 45m
ORD11:30 amChicago O'Hare Intl
Jun 1
ORD12:10 pmChicago O'Hare Intl
1h 40m
CGI1:50 pmCape Girardeau
$126

United Airlines flights from Missouri to Illinois

Our best United Airlines deals on Missouri to Illinois flight tickets
United Airlines
Apr 27
COU3:23 pmColumbia Regional
1h 33m
ORD4:56 pmChicago O'Hare Intl
May 16
ORD1:00 pmChicago O'Hare Intl
1h 32m
COU2:32 pmColumbia Regional
$179
United Airlines
Jul 6
COU11:23 amColumbia Regional
1h 42m
ORD1:05 pmChicago O'Hare Intl
Jul 11
ORD8:08 pmChicago O'Hare Intl
1h 51m
COU9:59 pmColumbia Regional
$187
United Airlines
May 21
COU11:23 amColumbia Regional
1h 42m
ORD1:05 pmChicago O'Hare Intl
May 24
ORD9:15 amChicago O'Hare Intl
1h 33m
COU10:48 amColumbia Regional
$192

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Missouri to Illinois that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cape GirardeauChicago

CGI - ORD

CGIORD

Cape Girardeau

Thu 3/12

9:25 am-11:10 am

Nonstop1h 45m

Chicago O'Hare Intl

Sat 3/14

11:50 am-1:30 pm

Nonstop1h 40m

$123

Cape GirardeauChicago

CGI - ORD

CGIORD

Cape Girardeau

Thu 3/12

9:25 am-11:10 am

Nonstop1h 45m

Chicago O'Hare Intl

Mon 3/16

11:50 am-1:30 pm

Nonstop1h 40m

$125

ColumbiaChicago

COU - ORD

COUORD

Columbia Regional

Mon 4/27

3:23 pm-4:56 pm

Nonstop1h 33m

Chicago O'Hare Intl

Sat 5/16

1:00 pm-2:32 pm

Nonstop1h 32m

$179

SpringfieldChicago

SGF - ORD

SGFORD

Springfield-Branson

Thu 4/9

5:19 am-7:07 am

Nonstop1h 48m

Chicago O'Hare Intl

Sun 4/12

3:43 pm-5:35 pm

Nonstop1h 52m

$189

ColumbiaChicago

COU - ORD

COUORD

Columbia Regional

Thu 5/21

11:23 am-1:05 pm

Nonstop1h 42m

Chicago O'Hare Intl

Sun 5/24

9:15 am-10:48 am

Nonstop1h 33m

$192

Kansas CitySt. Louis

MCI - STL

MCISTL

Kansas City

Fri 4/24

2:15 pm-7:21 pm

1 stop5h 06m

Lambert-St Louis

Sun 4/26

8:06 pm-1:30 pm

1 stop17h 24m

$192

ColumbiaChicago

COU - ORD

COUORD

Columbia Regional

Fri 3/13

6:30 pm-8:05 pm

Nonstop1h 35m

Chicago O'Hare Intl

Fri 3/20

6:50 pm-8:19 pm

Nonstop1h 29m

$194

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Sat 4/11

12:25 pm-4:55 pm

1 stop4h 30m

Chicago Midway

Sat 4/18

9:15 am-10:30 am

Nonstop1h 15m

$197

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Thu 4/9

7:20 am-8:30 am

Nonstop1h 10m

Chicago Midway

Mon 4/13

3:50 pm-8:55 pm

1 stop5h 05m

$198

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Tue 3/24

11:27 am-8:23 am

1 stop20h 56m

Chicago O'Hare Intl

Tue 3/31

8:55 pm-9:48 am

2 stops12h 53m

$200

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Illinois from

How to get the cheapest flight ticket from Missouri to Illinois

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Illinois?

The cheapest month to fly to Illinois from Missouri is in August. Flight prices, which tend to average around $211, are often lower during this time because this is during the off-season. If you aren’t able to travel to Illinois during the month of August, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $225.

What is the cheapest day to depart on your flight to Illinois?

The cheapest day to depart from Missouri to Illinois is on a Thursday when prices can be found for as low as $659. Flights from Missouri to Illinois on a Monday will generally be more expensive and average around $840. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Illinois?

Our most recent data shows that the best time of day to fly to Illinois is in the morning. Flights from Missouri to Illinois during this time can be as low as $581. Flights at noon are often more expensive with an average ticket price of $1,149.

What is the cheapest Missouri to Illinois flight route?

Fly from Kirksville Cannon Memorial to Chicago O'Hare Intl for the best Missouri - Illinois flight prices

How far in advance should I book a flight to Illinois?

You are more likely to see cheaper flights to Illinois from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Illinois for around $293 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Illinois from Missouri for as low as $168 on momondo.

What cabin class options are available on Missouri to Illinois flights?

There are 4 cabin classes available to choose from on Missouri to Illinois flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Missouri to Illinois flights?

No. A direct flight is the cheapest option for a flight between Missouri to Illinois.

Cheap Missouri to Illinois flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Illinois

Best Price Found

$57

Fastest flight time

1h 05m

Direct flights

Every day

Airports in Illinois

98 airports
The best one-way flight to Illinois from Missouri in the past 72 hours is $57. The best round-trip flight deal from Missouri to Illinois found on momondo in the last 72 hours is $350.
The fastest flight from Missouri to Illinois takes 1h 05m
Direct flights go from Missouri to Illinois every day.
There are 98 airports in Illinois. From Missouri there are direct flights to Chicago Midway (MDW), Lambert-St Louis (STL).
Search flight deals

  • When did momondo last update prices for flights from Missouri to Illinois?

    Prices for flights from Missouri to Illinois refresh daily.

  • How many operators does momondo search for flights from Missouri to Illinois?

  • How old do you have to be to fly from Missouri to Illinois?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Illinois.

  • What documentation or ID do you need to fly to Illinois?

    The required travel and health documents for your Illinois trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Illinois. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Missouri to Illinois?

Best airlines flying from Missouri to Illinois

Compare and see reviews for airlines that fly from Missouri to Illinois with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $97Free CancellationRating
7.1
11,368 reviews
Search American Airlines flights
United AirlinesPriceFrom $109Free CancellationRating
7.4
9,360 reviews
Search United Airlines flights
SouthwestPriceFrom $117Free CancellationRating
8.0
4,301 reviews
Search Southwest flights
ContourPriceFrom $118Free CancellationRating
7.6
42 reviews
Search Contour flights
Southern / MokulelePriceFrom $140Free CancellationRating
0.0
0 reviews
Search Southern / Mokulele flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Illinois?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Illinois from Missouri.

Can I find flights from Missouri to Illinois with flexible booking policies on momondo?

Yes. All flights to Illinois from Missouri on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Missouri to Illinois?

momondo helps you find the best flight between Missouri and Illinois by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Illinois right now. Can momondo alert me if prices change?

Price alerts on flights to Illinois from Missouri are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Illinois trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to Illinois

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