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Cheap flights from Minnesota to Florence from $396

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minnesota to Florence departing on 8/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Minnesota to Florence

Cheap round-trip flights

American Airlines Logo
6:00 am - 5:12 pmMSP-FLO
10h 12m2 stops
American Airlines Logo
5:14 am - 4:48 pmFLO-MSP
12h 34m2 stops
$408American Airlines
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Fri, Sep 12 - Sun, Sep 14
American Airlines Logo
3:02 pm - 11:16 pmMSP-FLO
7h 14m1 stop
American Airlines Logo
5:14 am - 9:01 amFLO-MSP
4h 47m1 stop
$475American Airlines
Find Deal
Fri, Sep 12 - Sun, Sep 14
American Airlines Logo
6:05 am - 5:12 pmMSP-FLO
10h 07m2 stops
American Airlines Logo
11:18 am - 4:45 pmFLO-MSP
6h 27m1 stop
$480American Airlines
Find Deal
Fri, Sep 12 - Sun, Sep 14
American Airlines Logo
5:45 pm - 12:03 amMSP-FLO
5h 18m1 stop
American Airlines Logo
5:15 am - 9:19 amFLO-MSP
5h 04m1 stop
$555American Airlines
Find Deal
Sat, Nov 22 - Sat, Nov 29
American Airlines Logo
10:49 am - 12:03 amMSP-FLO
12h 14m2 stops
American Airlines Logo
5:15 am - 9:19 amFLO-MSP
5h 04m1 stop
$560American Airlines
Find Deal
Sat, Nov 22 - Sat, Nov 29
American Airlines Logo
10:49 am - 12:03 amMSP-FLO
12h 14m2 stops
American Airlines Logo
5:15 am - 11:27 amFLO-MSP
7h 12m2 stops
$722American Airlines
Find Deal
Sat, Nov 22 - Sat, Nov 29
American Airlines Logo
6:08 am - 11:46 amMSP-FLO
4h 38m1 stop
American Airlines Logo
11:15 am - 5:09 pmFLO-MSP
6h 54m1 stop
$835American Airlines
Find Deal
Mon, Aug 18 - Thu, Aug 21
American Airlines Logo
6:08 am - 11:46 amMSP-FLO
4h 38m1 stop
American Airlines Logo
5:09 am - 12:09 pmFLO-MSP
8h 00m2 stops
$840American Airlines
Find Deal
Mon, Aug 18 - Thu, Aug 21
American Airlines Logo
6:09 am - 3:04 pmMSP-FLO
7h 55m2 stops
American Airlines Logo
2:34 pm - 10:50 pmFLO-MSP
9h 16m2 stops
$845American Airlines
Find Deal
Mon, Aug 18 - Thu, Aug 21

American Airlines flights from Minnesota to Florence, South Carolina

Our best American Airlines deals on Minnesota to Florence, South Carolina flight tickets
American Airlines
Sep 12
MSP6:00 amMinneapolis St Paul
10h 12m
2 stops
FLO5:12 pmFlorence
Sep 14
FLO5:14 amFlorence
12h 34m
2 stops
MSP4:48 pmMinneapolis St Paul
$408
Find similar
American Airlines
Sep 12
MSP3:02 pmMinneapolis St Paul
7h 14m
1 stop
FLO11:16 pmFlorence
Sep 14
FLO5:14 amFlorence
4h 47m
1 stop
MSP9:01 amMinneapolis St Paul
$475
Find similar
American Airlines
Sep 12
MSP6:05 amMinneapolis St Paul
10h 07m
2 stops
FLO5:12 pmFlorence
Sep 14
FLO11:18 amFlorence
6h 27m
1 stop
MSP4:45 pmMinneapolis St Paul
$480
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Minnesota to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from Minnesota to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 9/12

6:00 am-5:12 pm

2 stops10h 12m

Florence

Sun 9/14

5:14 am-4:48 pm

2 stops12h 34m

$408

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 9/12

3:02 pm-11:16 pm

1 stop7h 14m

Florence

Sun 9/14

5:14 am-9:01 am

1 stop4h 47m

$475

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 9/12

6:05 am-5:12 pm

2 stops10h 07m

Florence

Sun 9/14

11:18 am-4:45 pm

1 stop6h 27m

$480

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 11/22

5:45 pm-12:03 am

1 stop5h 18m

Florence

Sat 11/29

5:15 am-9:19 am

1 stop5h 04m

$555

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 11/22

10:49 am-12:03 am

2 stops12h 14m

Florence

Sat 11/29

5:15 am-9:19 am

1 stop5h 04m

$560

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 11/22

10:49 am-12:03 am

2 stops12h 14m

Florence

Sat 11/29

5:15 am-11:27 am

2 stops7h 12m

$722

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Mon 8/18

6:08 am-11:46 am

1 stop4h 38m

Florence

Thu 8/21

11:15 am-5:09 pm

1 stop6h 54m

$835

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Mon 8/18

6:08 am-11:46 am

1 stop4h 38m

Florence

Thu 8/21

5:09 am-12:09 pm

2 stops8h 00m

$840

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Mon 8/18

6:09 am-3:04 pm

2 stops7h 55m

Florence

Thu 8/21

2:34 pm-10:50 pm

2 stops9h 16m

$845

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Thu 8/21

7:48 pm-11:46 am

2 stops14h 58m

$396

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Minnesota to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Minnesota to Florence?

American Airlines is the most popular carrier operating from Minnesota to Florence

What airlines fly to Florence, South Carolina?

Delta, American Airlines and Sun Country Air are the top three most popular airlines that fly to Florence, South Carolina from Minnesota according to our data. Delta is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 7 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Minnesota to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minnesota to Florence, South Carolina

Best Price Found

$396

Fastest flight time

4h 38m

Direct flights

None

Airports in Florence, South Carolina

1 airport
The best one-way flight to Florence, South Carolina from Minnesota in the past 72 hours is $396. The best round-trip flight deal from Minnesota to Florence, South Carolina found on momondo in the last 72 hours is $408.
The fastest flight from Minnesota to Florence, South Carolina takes 4h 38m
There are no direct flights from Minnesota to Florence, South Carolina. Popular non-direct route for this connection is Minneapolis St Paul Airport - Florence Airport.
There is 1 airport near Florence, South Carolina: Florence (FLO)
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  • When did momondo last update prices for flights from Minnesota to Florence Airport?

    Prices for flights from Minnesota to Florence Airport refresh daily.

  • How old do you have to be to fly from Minnesota to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minnesota to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Minnesota to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Minnesota.

Can I find flights from Minnesota to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Minnesota with this policy.

How can momondo help me find flights from Minnesota to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Minnesota to Florence.

I’m not ready to book a flight from Minnesota to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Minnesota to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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