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Cheap flights from Minnesota to Florence from $495

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Minnesota to Florence departing on 11/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Minnesota to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
9:59 am - 6:07 pm
MSP
-
FLO
7h 08m
1 stop
American Airlines Logo
11:11 am - 11:59 pm
FLO
-
MSP
13h 48m
2 stops
$495American Airlines
Fri, Nov 6 - Tue, Nov 10
American Airlines Logo
9:59 am - 6:07 pm
MSP
-
FLO
7h 08m
1 stop
American Airlines Logo
11:11 am - 11:02 pm
FLO
-
MSP
12h 51m
2 stops
$498American Airlines
Fri, Nov 6 - Tue, Nov 10
American Airlines Logo
6:24 am - 6:07 pm
MSP
-
FLO
10h 43m
2 stops
American Airlines Logo
11:11 am - 11:02 pm
FLO
-
MSP
12h 51m
2 stops
$500American Airlines
Fri, Nov 6 - Tue, Nov 10
American Airlines Logo
6:24 am - 6:07 pm
MSP
-
FLO
10h 43m
2 stops
American Airlines Logo
11:11 am - 11:02 pm
FLO
-
MSP
12h 51m
2 stops
$503American Airlines
Fri, Nov 6 - Tue, Nov 10
American Airlines Logo
9:59 am - 6:07 pm
MSP
-
FLO
7h 08m
1 stop
American Airlines Logo
6:33 pm - 11:08 pm
FLO
-
MSP
5h 35m
1 stop
$518American Airlines
Fri, Nov 6 - Tue, Nov 10
American Airlines Logo
6:28 am - 10:00 pm
MSP
-
FLO
14h 32m
2 stops
American Airlines Logo
5:05 am - 10:05 am
FLO
-
MSP
6h 00m
1 stop
$573American Airlines
Mon, Jun 8 - Sun, Jun 14
American Airlines Logo
6:28 am - 10:00 pm
MSP
-
FLO
14h 32m
2 stops
American Airlines Logo
5:05 am - 3:34 pm
FLO
-
MSP
11h 29m
2 stops
$578American Airlines
Mon, Jun 8 - Sun, Jun 14
American Airlines Logo
1:37 pm - 10:00 pm
MSP
-
FLO
7h 23m
1 stop
American Airlines Logo
5:05 am - 10:05 am
FLO
-
MSP
6h 00m
1 stop
$597American Airlines
Mon, Jun 8 - Sun, Jun 14
American Airlines Logo
6:25 am - 10:00 pm
MSP
-
FLO
14h 35m
2 stops
American Airlines Logo
5:05 am - 3:17 pm
FLO
-
MSP
11h 12m
2 stops
$731American Airlines
Sun, May 24 - Thu, May 28
American Airlines Logo
6:25 am - 10:00 pm
MSP
-
FLO
14h 35m
2 stops
American Airlines Logo
5:05 am - 10:05 am
FLO
-
MSP
6h 00m
1 stop
$918American Airlines
Sun, May 24 - Thu, May 28

American Airlines flights from Minnesota to Florence, South Carolina

Our best American Airlines deals on Minnesota to Florence, South Carolina flight tickets
American Airlines
Nov 6
MSP9:59 amMinneapolis St Paul
7h 08m
1 stop
FLO6:07 pmFlorence
Nov 10
FLO11:11 amFlorence
13h 48m
2 stops
MSP11:59 pmMinneapolis St Paul
$495
American Airlines
Nov 6
MSP9:59 amMinneapolis St Paul
7h 08m
1 stop
FLO6:07 pmFlorence
Nov 10
FLO11:11 amFlorence
12h 51m
2 stops
MSP11:02 pmMinneapolis St Paul
$498
American Airlines
Nov 6
MSP6:24 amMinneapolis St Paul
10h 43m
2 stops
FLO6:07 pmFlorence
Nov 10
FLO11:11 amFlorence
12h 51m
2 stops
MSP11:02 pmMinneapolis St Paul
$500

momondo Fare Finder

 
Customize your flight search to find flights from Minnesota to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Minnesota to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 11/6

9:59 am-6:07 pm

1 stop7h 08m

Florence

Tue 11/10

11:11 am-11:59 pm

2 stops13h 48m

$495

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 11/6

9:59 am-6:07 pm

1 stop7h 08m

Florence

Tue 11/10

11:11 am-11:02 pm

2 stops12h 51m

$498

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 11/6

6:24 am-6:07 pm

2 stops10h 43m

Florence

Tue 11/10

11:11 am-11:02 pm

2 stops12h 51m

$500

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 11/6

6:24 am-6:07 pm

2 stops10h 43m

Florence

Tue 11/10

11:11 am-11:02 pm

2 stops12h 51m

$503
Quickest round-trip

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 11/6

9:59 am-6:07 pm

1 stop7h 08m

Florence

Tue 11/10

6:33 pm-11:08 pm

1 stop5h 35m

$518

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Mon 6/8

6:28 am-10:00 pm

2 stops14h 32m

Florence

Sun 6/14

5:05 am-10:05 am

1 stop6h 00m

$573

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Mon 6/8

6:28 am-10:00 pm

2 stops14h 32m

Florence

Sun 6/14

5:05 am-3:34 pm

2 stops11h 29m

$578

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Mon 6/8

1:37 pm-10:00 pm

1 stop7h 23m

Florence

Sun 6/14

5:05 am-10:05 am

1 stop6h 00m

$597

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sun 5/24

6:25 am-10:00 pm

2 stops14h 35m

Florence

Thu 5/28

5:05 am-3:17 pm

2 stops11h 12m

$731

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sun 5/24

6:25 am-10:00 pm

2 stops14h 35m

Florence

Thu 5/28

5:05 am-10:05 am

1 stop6h 00m

$918

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Minnesota to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

Delta, American Airlines and Sun Country Air are the top three most popular airlines that fly to Florence, South Carolina from Minnesota according to our data. Delta is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Minnesota to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minnesota to Florence, South Carolina

Fastest flight time

7h 08m

Direct flights

None
The fastest flight from Minnesota to Florence, South Carolina takes 7h 08m
There are no direct flights from Minnesota to Florence, South Carolina. There are no popular flight routes from Minnesota to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Minnesota to Florence, South Carolina

  • When did momondo last update prices for flights from Minnesota to Florence Airport?

    Prices for flights from Minnesota to Florence Airport refresh daily.

  • How many operators does momondo search for flights from Minnesota to Florence Airport?

  • How old do you have to be to fly from Minnesota to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minnesota to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Minnesota to Florence, South Carolina

Compare and see reviews for airlines that fly from Minnesota to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $295Free CancellationRating
7.1
11,662 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington
Bennettsville
Lake City

Why use momondo?

Why should I use momondo to find a flight deal from Minnesota to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Minnesota.

Can I find flights from Minnesota to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Minnesota with this policy.

How can momondo help me find flights from Minnesota to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Minnesota to Florence.

I’m not ready to book a flight from Minnesota to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Minnesota to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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