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Cheap flights from Minnesota to Florence from $455

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Minnesota to Florence departing on 4/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Minnesota to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:51 pm - 9:47 pm
MSP
-
FLO
4h 56m
1 stop
American Airlines Logo
5:20 am - 9:48 am
FLO
-
MSP
5h 28m
1 stop
$455American Airlines
Thu, Apr 9 - Wed, Apr 15
American Airlines Logo
3:51 pm - 9:47 pm
MSP
-
FLO
4h 56m
1 stop
American Airlines Logo
4:16 pm - 10:21 pm
FLO
-
MSP
7h 05m
2 stops
$460American Airlines
Thu, Apr 9 - Wed, Apr 15
American Airlines Logo
11:29 am - 9:47 pm
MSP
-
FLO
9h 18m
2 stops
American Airlines Logo
4:16 pm - 11:59 pm
FLO
-
MSP
8h 43m
2 stops
$466American Airlines
Thu, Apr 9 - Wed, Apr 15
American Airlines Logo
1:38 pm - 10:00 pm
MSP
-
FLO
7h 22m
1 stop
American Airlines Logo
5:05 am - 1:27 pm
FLO
-
MSP
9h 22m
2 stops
$519American Airlines
Fri, Jun 5 - Wed, Jun 10
American Airlines Logo
8:00 am - 10:00 pm
MSP
-
FLO
13h 00m
2 stops
American Airlines Logo
5:05 am - 1:27 pm
FLO
-
MSP
9h 22m
2 stops
$524American Airlines
Fri, Jun 5 - Wed, Jun 10
American Airlines Logo
6:02 pm - 12:02 am
MSP
-
FLO
5h 00m
1 stop
American Airlines Logo
5:14 am - 9:08 am
FLO
-
MSP
4h 54m
1 stop
$539American Airlines
Sat, Aug 8 - Tue, Aug 11
American Airlines Logo
6:02 pm - 12:02 am
MSP
-
FLO
5h 00m
1 stop
American Airlines Logo
2:34 pm - 10:24 pm
FLO
-
MSP
8h 50m
2 stops
$544American Airlines
Sat, Aug 8 - Tue, Aug 11
American Airlines Logo
6:00 am - 2:09 pm
MSP
-
FLO
7h 09m
1 stop
American Airlines Logo
5:14 am - 9:08 am
FLO
-
MSP
4h 54m
1 stop
$559American Airlines
Thu, Aug 6 - Tue, Aug 11
American Airlines Logo
6:00 am - 2:09 pm
MSP
-
FLO
7h 09m
1 stop
American Airlines Logo
2:34 pm - 10:24 pm
FLO
-
MSP
8h 50m
2 stops
$564American Airlines
Thu, Aug 6 - Tue, Aug 11
American Airlines Logo
6:02 pm - 12:02 am
MSP
-
FLO
5h 00m
1 stop
American Airlines Logo
5:14 am - 9:08 am
FLO
-
MSP
4h 54m
1 stop
$582American Airlines
Fri, Aug 7 - Tue, Aug 11

American Airlines flights from Minnesota to Florence, South Carolina

Our best American Airlines deals on Minnesota to Florence, South Carolina flight tickets
American Airlines
Apr 9
MSP3:51 pmMinneapolis St Paul
4h 56m
1 stop
FLO9:47 pmFlorence
Apr 15
FLO5:20 amFlorence
5h 28m
1 stop
MSP9:48 amMinneapolis St Paul
$455
American Airlines
Apr 9
MSP3:51 pmMinneapolis St Paul
4h 56m
1 stop
FLO9:47 pmFlorence
Apr 15
FLO4:16 pmFlorence
7h 05m
2 stops
MSP10:21 pmMinneapolis St Paul
$460
American Airlines
Apr 9
MSP11:29 amMinneapolis St Paul
9h 18m
2 stops
FLO9:47 pmFlorence
Apr 15
FLO4:16 pmFlorence
8h 43m
2 stops
MSP11:59 pmMinneapolis St Paul
$466

momondo Fare Finder

 
Customize your flight search to find flights from Minnesota to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Minnesota to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Thu 4/9

3:51 pm-9:47 pm

1 stop4h 56m

Florence

Wed 4/15

5:20 am-9:48 am

1 stop5h 28m

$455

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Thu 4/9

3:51 pm-9:47 pm

1 stop4h 56m

Florence

Wed 4/15

4:16 pm-10:21 pm

2 stops7h 05m

$460

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Thu 4/9

11:29 am-9:47 pm

2 stops9h 18m

Florence

Wed 4/15

4:16 pm-11:59 pm

2 stops8h 43m

$466

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 6/5

1:38 pm-10:00 pm

1 stop7h 22m

Florence

Wed 6/10

5:05 am-1:27 pm

2 stops9h 22m

$519

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 6/5

8:00 am-10:00 pm

2 stops13h 00m

Florence

Wed 6/10

5:05 am-1:27 pm

2 stops9h 22m

$524
Quickest round-trip

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 8/8

6:02 pm-12:02 am

1 stop5h 00m

Florence

Tue 8/11

5:14 am-9:08 am

1 stop4h 54m

$539

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 8/8

6:02 pm-12:02 am

1 stop5h 00m

Florence

Tue 8/11

2:34 pm-10:24 pm

2 stops8h 50m

$544

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Thu 8/6

6:00 am-2:09 pm

1 stop7h 09m

Florence

Tue 8/11

5:14 am-9:08 am

1 stop4h 54m

$559

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Thu 8/6

6:00 am-2:09 pm

1 stop7h 09m

Florence

Tue 8/11

2:34 pm-10:24 pm

2 stops8h 50m

$564

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Fri 8/7

6:02 pm-12:02 am

1 stop5h 00m

Florence

Tue 8/11

5:14 am-9:08 am

1 stop4h 54m

$582

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Minnesota to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

Delta, American Airlines and Sun Country Air are the top three most popular airlines that fly to Florence, South Carolina from Minnesota according to our data. Delta is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Minnesota to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minnesota to Florence, South Carolina

Fastest flight time

4h 56m

Direct flights

None
The fastest flight from Minnesota to Florence, South Carolina takes 4h 56m
There are no direct flights from Minnesota to Florence, South Carolina. There are no popular flight routes from Minnesota to Florence, South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Minnesota to Florence Airport?

    Prices for flights from Minnesota to Florence Airport refresh daily.

  • How old do you have to be to fly from Minnesota to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minnesota to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Minnesota to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Minnesota.

Can I find flights from Minnesota to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Minnesota with this policy.

How can momondo help me find flights from Minnesota to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Minnesota to Florence.

I’m not ready to book a flight from Minnesota to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Minnesota to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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