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Cheap flights from Minneapolis to South Carolina from $78

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to South Carolina departing on 1/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Minneapolis to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Sun Country Air Logo
8:20 am - 12:01 pm
MSP
-
CHS
2h 41mnonstop
Sun Country Air Logo
1:04 pm - 3:04 pm
CHS
-
MSP
3h 00mnonstop
$138Sun Country Air
Mon, Jun 8 - Thu, Jun 11
Sun Country Air Logo
8:20 am - 12:01 pm
MSP
-
CHS
2h 41mnonstop
Sun Country Air Logo
12:58 pm - 2:58 pm
CHS
-
MSP
3h 00mnonstop
$158Sun Country Air
Fri, Jun 5 - Mon, Jun 8
Sun Country Air Logo
8:20 am - 12:01 pm
MSP
-
CHS
2h 41mnonstop
Sun Country Air Logo
12:58 pm - 2:58 pm
CHS
-
MSP
3h 00mnonstop
$167Sun Country Air
Fri, Jun 5 - Mon, Jun 8
American Airlines Logo
2:43 pm - 8:54 pm
MSP
-
MYR
5h 11m1 stop
American Airlines Logo
5:38 pm - 11:39 pm
MYR
-
MSP
7h 01m1 stop
$251American Airlines
Tue, Feb 10 - Tue, Feb 17
Delta Logo
6:10 pm - 9:39 pm
MSP
-
CLT
2h 29mnonstop
Delta Logo
6:00 am - 7:57 am
CLT
-
MSP
2h 57mnonstop
$255Delta
Sat, Jan 17 - Sun, Jan 18
American Airlines Logo
12:31 pm - 11:57 pm
MSP
-
MYR
10h 26m2 stops
American Airlines Logo
6:38 pm - 11:44 pm
MYR
-
MSP
6h 06m1 stop
$256American Airlines
Tue, Feb 10 - Tue, Feb 17
Delta Logo
7:30 am - 11:02 am
MSP
-
CLT
2h 32mnonstop
Delta Logo
5:30 am - 9:07 am
CLT
-
MSP
4h 37m1 stop
$265Delta
Sat, May 23 - Sat, May 30
United Airlines Logo
12:10 pm - 10:46 pm
MSP
-
SAV
9h 36m2 stops
United Airlines Logo
4:46 pm - 9:57 pm
SAV
-
MSP
6h 11m1 stop
$284United Airlines
Tue, Jan 20 - Tue, Jan 27
United Airlines Logo
9:55 am - 4:26 pm
MSP
-
CAE
5h 31m1 stop
United Airlines Logo
5:07 pm - 9:57 pm
CAE
-
MSP
5h 50m1 stop
$294United Airlines
Fri, Jan 9 - Sun, Jan 11
Southwest Logo
7:45 am - 5:35 pm
MSP
-
GSP
8h 50m2 stops
Southwest Logo
10:05 am - 8:35 pm
GSP
-
MSP
11h 30m2 stops
$327Southwest
Tue, Jan 27 - Tue, Feb 3

Frontier flights from Minneapolis to South Carolina

Our best Frontier deals on Minneapolis to South Carolina flight tickets
Frontier
Jan 22
MSP6:45 amMinneapolis St Paul
13h 18m
2 stops
CLT9:03 pmCharlotte Douglas
Jan 25
CLT5:13 pmCharlotte Douglas
7h 44m
1 stop
MSP11:57 pmMinneapolis St Paul
$256
Find similar
Frontier
Jan 3
MSP8:42 pmMinneapolis St Paul
13h 40m
1 stop
CLT11:22 amCharlotte Douglas
Jan 12
CLT9:47 amCharlotte Douglas
10h 06m
1 stop
MSP6:53 pmMinneapolis St Paul
$257
Find similar
Frontier
Jan 8
MSP7:48 pmMinneapolis St Paul
12h 14m
2 stops
CLT9:02 amCharlotte Douglas
Jan 12
CLT9:47 amCharlotte Douglas
10h 06m
1 stop
MSP6:53 pmMinneapolis St Paul
$258
Find similar

United Airlines flights from Minneapolis to South Carolina

Our best United Airlines deals on Minneapolis to South Carolina flight tickets
United Airlines
May 23
MSP11:32 amMinneapolis St Paul
4h 35m
1 stop
CLT5:07 pmCharlotte Douglas
May 27
CLT10:40 amCharlotte Douglas
7h 21m
1 stop
MSP5:01 pmMinneapolis St Paul
$270
Find similar
United Airlines
Jan 20
MSP12:10 pmMinneapolis St Paul
9h 36m
2 stops
SAV10:46 pmSavannah/Hilton Head
Jan 27
SAV4:46 pmSavannah/Hilton Head
6h 11m
1 stop
MSP9:57 pmMinneapolis St Paul
$284
Find similar
United Airlines
Jan 26
MSP9:55 amMinneapolis St Paul
6h 29m
1 stop
CLT5:24 pmCharlotte Douglas
Jan 31
CLT11:15 amCharlotte Douglas
6h 20m
1 stop
MSP4:35 pmMinneapolis St Paul
$290
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Minneapolis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Minneapolis to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisCharleston

MSP - CHS

MSPCHS

Minneapolis St Paul

Mon 6/8

8:20 am-12:01 pm

Nonstop2h 41m

Charleston

Thu 6/11

1:04 pm-3:04 pm

Nonstop3h 00m

$138

MinneapolisCharleston

MSP - CHS

MSPCHS

Minneapolis St Paul

Fri 6/5

8:20 am-12:01 pm

Nonstop2h 41m

Charleston

Mon 6/8

12:58 pm-2:58 pm

Nonstop3h 00m

$158

MinneapolisCharleston

MSP - CHS

MSPCHS

Minneapolis St Paul

Fri 6/5

8:20 am-12:01 pm

Nonstop2h 41m

Charleston

Mon 6/8

12:58 pm-2:58 pm

Nonstop3h 00m

$167

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

Tue 2/10

2:43 pm-8:54 pm

1 stop5h 11m

Myrtle Beach Intl

Tue 2/17

5:38 pm-11:39 pm

1 stop7h 01m

$251

MinneapolisCharlotte

MSP - CLT

MSPCLT

Minneapolis St Paul

Sat 1/17

6:10 pm-9:39 pm

Nonstop2h 29m

Charlotte Douglas

Sun 1/18

6:00 am-7:57 am

Nonstop2h 57m

$255

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

Tue 2/10

12:31 pm-11:57 pm

2 stops10h 26m

Myrtle Beach Intl

Tue 2/17

6:38 pm-11:44 pm

1 stop6h 06m

$256

MinneapolisCharlotte

MSP - CLT

MSPCLT

Minneapolis St Paul

Sat 5/23

7:30 am-11:02 am

Nonstop2h 32m

Charlotte Douglas

Sat 5/30

5:30 am-9:07 am

1 stop4h 37m

$265

MinneapolisSavannah

MSP - SAV

MSPSAV

Minneapolis St Paul

Tue 1/20

12:10 pm-10:46 pm

2 stops9h 36m

Savannah/Hilton Head

Tue 1/27

4:46 pm-9:57 pm

1 stop6h 11m

$284

MinneapolisColumbia

MSP - CAE

MSPCAE

Minneapolis St Paul

Fri 1/9

9:55 am-4:26 pm

1 stop5h 31m

Columbia Metropolitan

Sun 1/11

5:07 pm-9:57 pm

1 stop5h 50m

$294

MinneapolisGreenville

MSP - GSP

MSPGSP

Minneapolis St Paul

Tue 1/27

7:45 am-5:35 pm

2 stops8h 50m

Greenville

Tue 2/3

10:05 am-8:35 pm

2 stops11h 30m

$327

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Minneapolis to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Minneapolis is in June. Flight prices, which tend to average around $298, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of June, then book flights to South Carolina from Minneapolis during January instead. Flights to South Carolina in January, while not as cheap as those in June, still average around $309.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Sunday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $266. The most expensive day to fly to South Carolina is Thursday, with ticket prices averaging around $392.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Minneapolis to South Carolina flights are usually those with departure times in the morning. Our users have found flights to South Carolina in the morning for as low as $349. Try not to purchase tickets at noon because they tend to be around $478. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Minneapolis St Paul to South Carolina flight route?

Fly from Minneapolis St Paul to Myrtle Beach Intl for the best Minneapolis St Paul - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $345 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Minneapolis for as low as $272 on momondo.

What cabin class options are available on Minneapolis St Paul to South Carolina flights?

There are 2 cabin classes available to choose from on Minneapolis St Paul to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Minneapolis to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Minneapolis to South Carolina.

Cheap Minneapolis to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to South Carolina

Best Price Found

$308

Fastest flight time

2h 28m

Direct flights

Every day

Airports in South Carolina

57 airports
The best one-way flight to South Carolina from Minneapolis in the past 72 hours is $308. The best round-trip flight deal from Minneapolis to South Carolina found on momondo in the last 72 hours is $259.
The fastest flight from Minneapolis to South Carolina takes 2h 28m
Direct flights go from Minneapolis to South Carolina every day.
There are 57 airports in South Carolina. From Minneapolis there are direct flights to Myrtle Beach Intl (MYR), Savannah/Hilton Head (SAV), Charlotte Douglas (CLT), Charleston (CHS).
Search flight deals

  • When did momondo last update prices for flights from Minneapolis St Paul Airport to South Carolina?

    Prices for flights from Minneapolis St Paul Airport to South Carolina refresh daily.

  • How many operators does momondo search for flights from Minneapolis St Paul Airport to South Carolina?

  • How old do you have to be to fly from Minneapolis St Paul Airport to South Carolina?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Minneapolis to South Carolina?

Best airlines flying from Minneapolis to South Carolina

Compare and see reviews for airlines that fly from Minneapolis to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Sun Country AirPriceFrom $69Free CancellationRating
6.9
334 reviews
Search Sun Country Air flights
Spirit AirlinesPriceFrom $145Free CancellationRating
6.3
8,194 reviews
Search Spirit Airlines flights
DeltaPriceFrom $208Free CancellationRating
7.9
8,014 reviews
Search Delta flights
United AirlinesPriceFrom $218Free CancellationRating
7.4
9,106 reviews
Search United Airlines flights
American AirlinesPriceFrom $218Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights
SouthwestPriceFrom $242Free CancellationRating
8.0
4,253 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to South Carolina?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South Carolina from Minneapolis.

Can I find flights from Minneapolis to South Carolina with flexible booking policies on momondo?

Flights from Minneapolis to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Minneapolis to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Minneapolis.

I’m not ready to book a flight from Minneapolis to South Carolina right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Minneapolis to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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