Cheap flights from Michigan to Panama City from $157

The cheapest month to fly to Panama City, Florida from Michigan is in January. Flight prices, which tend to average around $307, are often lower during this time because this is during the off-season. The month of September is another great option to travel to Panama City, Florida, with average flight prices from Michigan averaging around $314.

Fly from Detroit Metropolitan Wayne County to Panama City NW Florida Beaches for the best Michigan - Panama City NW Florida Beaches flight prices

You are more likely to see cheaper flights to Panama City, Florida from Michigan when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $420 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Michigan for as low as $268 on momondo.

There are 2 cabin classes available to choose from on Michigan to Panama City, Florida flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Delta, United Airlines, and Southwest are the most popular carriers operating from Michigan to Panama City NW Florida Beaches

American Airlines, Allegiant Air and Delta are the top three most popular airlines that fly to Panama City, Florida from Michigan according to our data. American Airlines is the first choice among our users, with 32% of people opting to fly with this airline when traveling to Panama City, Florida. Keep in mind that there are 6 different airlines that fly to Panama City, Florida on a routine basis, so you have a few additional options to choose from.

As of August 2026, there are 12 flights per week flying from Michigan to Panama City, Florida. The most common day of the week flights depart is Mon, with 25% of flights taking off on this day.

Flight times vary depending on what airport in Michigan you fly out of and what airport in Panama City, Florida you fly into. For example, flying from Detroit to Pensacola takes 4h 23m on average. On the other hand, flying from Grand Rapids to Pensacola takes 4h 33m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.