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Cheap flights from Medford to Greenville from $588

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Medford to Greenville departing on 2/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Medford to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:25 pm - 10:01 am
MFR
-
GSP
12h 36m
2 stops
United Airlines Logo
4:16 pm - 10:56 am
GSP
-
MFR
21h 40m
2 stops
$588United Airlines
Wed, Feb 25 - Sat, Feb 28
United Airlines Logo
7:00 am - 11:59 pm
MFR
-
GSP
13h 59m
2 stops
United Airlines Logo
4:16 pm - 10:56 am
GSP
-
MFR
21h 40m
2 stops
$603United Airlines
Wed, Feb 25 - Sat, Feb 28
United Airlines Logo
12:50 pm - 3:09 pm
MFR
-
GSP
23h 19m
1 stop
United Airlines Logo
4:10 pm - 9:37 pm
GSP
-
MFR
8h 27m
1 stop
$611United Airlines
Sat, Apr 4 - Fri, Apr 17
United Airlines Logo
2:12 pm - 3:09 pm
MFR
-
GSP
21h 57m
2 stops
United Airlines Logo
4:10 pm - 9:37 pm
GSP
-
MFR
8h 27m
1 stop
$616United Airlines
Sat, Apr 4 - Fri, Apr 17
United Airlines Logo
6:25 pm - 10:01 am
MFR
-
GSP
12h 36m
2 stops
United Airlines Logo
4:16 pm - 9:18 pm
GSP
-
MFR
8h 02m
1 stop
$640United Airlines
Wed, Feb 25 - Sat, Feb 28
United Airlines Logo
5:02 am - 3:15 pm
MFR
-
GSP
7h 13m
1 stop
United Airlines Logo
10:00 am - 10:28 pm
GSP
-
MFR
15h 28m
2 stops
$646United Airlines
Thu, Feb 26 - Mon, Mar 2
United Airlines Logo
7:00 am - 11:59 pm
MFR
-
GSP
13h 59m
2 stops
United Airlines Logo
6:30 am - 10:28 pm
GSP
-
MFR
18h 58m
2 stops
$652United Airlines
Wed, Feb 25 - Sat, Feb 28
United Airlines Logo
6:25 pm - 10:01 am
MFR
-
GSP
12h 36m
2 stops
United Airlines Logo
4:16 pm - 10:56 am
GSP
-
MFR
21h 40m
2 stops
$658United Airlines
Wed, Feb 25 - Sat, Feb 28
United Airlines Logo
6:25 pm - 10:01 am
MFR
-
GSP
12h 36m
2 stops
United Airlines Logo
4:16 pm - 9:18 pm
GSP
-
MFR
8h 02m
1 stop
$672United Airlines
Wed, Feb 25 - Sat, Feb 28
American Airlines Logo
5:13 am - 8:46 pm
MFR
-
GSP
12h 33m
2 stops
American Airlines Logo
2:19 pm - 11:18 pm
GSP
-
MFR
11h 59m
2 stops
$694American Airlines
Thu, Feb 26 - Mon, Mar 2

United Airlines flights from Medford to Greenville

Our best United Airlines deals on Medford to Greenville flight tickets
United Airlines
Feb 25
MFR6:25 pmMedford
12h 36m
2 stops
GSP10:01 amGreenville
Feb 28
GSP4:16 pmGreenville
21h 40m
2 stops
MFR10:56 amMedford
$588
United Airlines
Feb 25
MFR7:00 amMedford
13h 59m
2 stops
GSP11:59 pmGreenville
Feb 28
GSP4:16 pmGreenville
21h 40m
2 stops
MFR10:56 amMedford
$603
United Airlines
Apr 4
MFR12:50 pmMedford
23h 19m
1 stop
GSP3:09 pmGreenville
Apr 17
GSP4:10 pmGreenville
8h 27m
1 stop
MFR9:37 pmMedford
$611

momondo Fare Finder

 
Customize your flight search to find flights from Medford to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Medford to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Wed 2/25

6:25 pm-10:01 am

2 stops12h 36m

Greenville

Sat 2/28

4:16 pm-10:56 am

2 stops21h 40m

$588

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Wed 2/25

7:00 am-11:59 pm

2 stops13h 59m

Greenville

Sat 2/28

4:16 pm-10:56 am

2 stops21h 40m

$603

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 4/4

12:50 pm-3:09 pm

1 stop23h 19m

Greenville

Fri 4/17

4:10 pm-9:37 pm

1 stop8h 27m

$611

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 4/4

2:12 pm-3:09 pm

2 stops21h 57m

Greenville

Fri 4/17

4:10 pm-9:37 pm

1 stop8h 27m

$616

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Wed 2/25

6:25 pm-10:01 am

2 stops12h 36m

Greenville

Sat 2/28

4:16 pm-9:18 pm

1 stop8h 02m

$640

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Thu 2/26

5:02 am-3:15 pm

1 stop7h 13m

Greenville

Mon 3/2

10:00 am-10:28 pm

2 stops15h 28m

$646

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Wed 2/25

7:00 am-11:59 pm

2 stops13h 59m

Greenville

Sat 2/28

6:30 am-10:28 pm

2 stops18h 58m

$652

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Wed 2/25

6:25 pm-10:01 am

2 stops12h 36m

Greenville

Sat 2/28

4:16 pm-10:56 am

2 stops21h 40m

$658

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Wed 2/25

6:25 pm-10:01 am

2 stops12h 36m

Greenville

Sat 2/28

4:16 pm-9:18 pm

1 stop8h 02m

$672

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Thu 2/26

5:13 am-8:46 pm

2 stops12h 33m

Greenville

Mon 3/2

2:19 pm-11:18 pm

2 stops11h 59m

$694

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Greenville from

How to get the cheapest flight ticket from Medford to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Greenville?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Greenville from Medford according to our data. United Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 3 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

When to book flights from Medford to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Medford to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Medford to Greenville (MFR to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to Greenville

Fastest flight time

7h 13m

Direct flights

None
The fastest flight from Medford to Greenville takes 7h 13m
There are no direct flights from Medford to Greenville. There are no popular flight routes from Medford to Greenville.
Search flight deals

  • How far is Medford to Greenville by plane?

    The distance between Medford and Greenville is about 2222.7 mi. By plane, this route typically takes 7h 13m.

  • When did momondo last update prices for flights from Medford Airport to Greenville Airport?

    Prices for flights from Medford Airport to Greenville Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Medford Airport to Greenville Airport?

  • How old do you have to be to fly from Medford Airport to Greenville Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Medford Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Medford to Greenville?

Best airlines flying from Medford to Greenville

Compare and see reviews for airlines that fly from Medford to Greenville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $175Free CancellationRating
7.4
9,279 reviews
Search United Airlines flights
DeltaPriceFrom $261Free CancellationRating
7.9
8,180 reviews
Search Delta flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Medford to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from Medford.

Can I find flights from Medford to Greenville with flexible booking policies on momondo?

All flight searches from Medford to Greenville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Medford to Greenville?

Once all potential Medford to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Medford to Greenville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Medford to Greenville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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