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Cheap flights from Medford to Greenville from $261

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Medford to Greenville departing on 6/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Medford to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:01 am - 9:47 pm
MFR
-
GSP
12h 46m
2 stops
Delta Logo
3:06 pm - 11:54 pm
GSP
-
MFR
11h 48m
2 stops
$558Delta
Wed, Jul 8 - Tue, Jul 14
Delta Logo
6:01 am - 9:47 pm
MFR
-
GSP
12h 46m
2 stops
Delta Logo
1:09 pm - 11:54 pm
GSP
-
MFR
13h 45m
2 stops
$589Delta
Tue, Jul 7 - Tue, Jul 14
Delta Logo
6:01 am - 9:47 pm
MFR
-
GSP
12h 46m
2 stops
Delta Logo
6:45 am - 4:47 pm
GSP
-
MFR
13h 02m
2 stops
$607Delta
Wed, Jul 8 - Wed, Jul 15
United Airlines Logo
6:35 pm - 9:55 am
MFR
-
GSP
12h 20m
2 stops
United Airlines Logo
4:15 pm - 9:16 pm
GSP
-
MFR
8h 01m
1 stop
$615United Airlines
Wed, Jun 17 - Wed, Jun 24
United Airlines Logo
5:00 am - 3:19 pm
MFR
-
GSP
7h 19m
1 stop
United Airlines Logo
4:15 pm - 9:16 pm
GSP
-
MFR
8h 01m
1 stop
$629United Airlines
Tue, Jun 30 - Tue, Jul 7
United Airlines Logo
6:35 pm - 9:55 am
MFR
-
GSP
12h 20m
2 stops
United Airlines Logo
4:15 pm - 9:16 pm
GSP
-
MFR
8h 01m
1 stop
$639United Airlines
Tue, Jul 7 - Mon, Jul 13
Delta Logo
5:25 pm - 10:47 am
MFR
-
GSP
14h 22m
2 stops
Delta Logo
1:09 pm - 11:54 pm
GSP
-
MFR
13h 45m
2 stops
$640Delta
Mon, Jul 6 - Tue, Jul 14
United Airlines Logo
6:00 am - 11:44 pm
MFR
-
GSP
14h 44m
2 stops
United Airlines Logo
4:15 pm - 9:16 pm
GSP
-
MFR
8h 01m
1 stop
$648United Airlines
Tue, Jun 30 - Tue, Jul 7
United Airlines Logo
6:00 am - 11:34 pm
MFR
-
GSP
14h 34m
2 stops
United Airlines Logo
4:15 pm - 9:16 pm
GSP
-
MFR
8h 01m
1 stop
$654United Airlines
Thu, Jul 9 - Wed, Jul 15
Alaska Airlines Logo
7:08 am - 10:56 pm
MFR
-
GSP
12h 48m
2 stops
Alaska Airlines Logo
11:33 am - 6:39 pm
GSP
-
MFR
10h 06m
2 stops
$662Alaska Airlines
Thu, Jun 4 - Tue, Jun 9

Alaska Airlines flights from Medford to Greenville

Our best Alaska Airlines deals on Medford to Greenville flight tickets
Alaska Airlines
Jun 4
MFR7:08 amMedford
12h 48m
2 stops
GSP10:56 pmGreenville
Jun 9
GSP11:33 amGreenville
10h 06m
2 stops
MFR6:39 pmMedford
$662
Alaska Airlines
Jun 4
MFR7:08 amMedford
13h 40m
2 stops
GSP11:48 pmGreenville
Jun 9
GSP1:37 pmGreenville
13h 22m
2 stops
MFR11:59 pmMedford
$688
Alaska Airlines
Jul 7
MFR7:35 pmMedford
12h 26m
2 stops
GSP11:01 amGreenville
Jul 13
GSP1:40 pmGreenville
13h 24m
2 stops
MFR12:04 amMedford
$702

United Airlines flights from Medford to Greenville

Our best United Airlines deals on Medford to Greenville flight tickets
United Airlines
Jun 17
MFR6:35 pmMedford
12h 20m
2 stops
GSP9:55 amGreenville
Jun 24
GSP4:15 pmGreenville
8h 01m
1 stop
MFR9:16 pmMedford
$615
United Airlines
Jun 30
MFR5:00 amMedford
7h 19m
1 stop
GSP3:19 pmGreenville
Jul 7
GSP4:15 pmGreenville
8h 01m
1 stop
MFR9:16 pmMedford
$629
United Airlines
Jul 7
MFR6:35 pmMedford
12h 20m
2 stops
GSP9:55 amGreenville
Jul 13
GSP4:15 pmGreenville
8h 01m
1 stop
MFR9:16 pmMedford
$639

momondo Fare Finder

 
Customize your flight search to find flights from Medford to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Medford to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Wed 7/8

6:01 am-9:47 pm

2 stops12h 46m

Greenville

Tue 7/14

3:06 pm-11:54 pm

2 stops11h 48m

$558

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Tue 7/7

6:01 am-9:47 pm

2 stops12h 46m

Greenville

Tue 7/14

1:09 pm-11:54 pm

2 stops13h 45m

$589

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Wed 7/8

6:01 am-9:47 pm

2 stops12h 46m

Greenville

Wed 7/15

6:45 am-4:47 pm

2 stops13h 02m

$607

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Wed 6/17

6:35 pm-9:55 am

2 stops12h 20m

Greenville

Wed 6/24

4:15 pm-9:16 pm

1 stop8h 01m

$615
Quickest round-trip

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Tue 6/30

5:00 am-3:19 pm

1 stop7h 19m

Greenville

Tue 7/7

4:15 pm-9:16 pm

1 stop8h 01m

$629

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Tue 7/7

6:35 pm-9:55 am

2 stops12h 20m

Greenville

Mon 7/13

4:15 pm-9:16 pm

1 stop8h 01m

$639

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Mon 7/6

5:25 pm-10:47 am

2 stops14h 22m

Greenville

Tue 7/14

1:09 pm-11:54 pm

2 stops13h 45m

$640

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Tue 6/30

6:00 am-11:44 pm

2 stops14h 44m

Greenville

Tue 7/7

4:15 pm-9:16 pm

1 stop8h 01m

$648

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Thu 7/9

6:00 am-11:34 pm

2 stops14h 34m

Greenville

Wed 7/15

4:15 pm-9:16 pm

1 stop8h 01m

$654

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Thu 6/4

7:08 am-10:56 pm

2 stops12h 48m

Greenville

Tue 6/9

11:33 am-6:39 pm

2 stops10h 06m

$662

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Medford to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Medford to Greenville flights?

You could potentially save up to 84% on your flight if you consider stops on a Medford to Greenville flight.

When to book flights from Medford to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Medford to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Medford to Greenville (MFR to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to Greenville

Fastest flight time

7h 19m

Direct flights

None
The fastest flight from Medford to Greenville takes 7h 19m
There are no direct flights from Medford to Greenville. There are no popular flight routes from Medford to Greenville.
Search flight deals

Frequently asked questions about flying from Medford to Greenville

  • How far is Medford to Greenville by plane?

    The distance between Medford and Greenville is about 2222.7 mi. By plane, this route typically takes 7h 19m.

  • When did momondo last update prices for flights from Medford Airport to Greenville Airport?

    Prices for flights from Medford Airport to Greenville Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Medford Airport to Greenville Airport?

  • How old do you have to be to fly from Medford Airport to Greenville Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Medford Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Medford to Greenville?

Best airlines flying from Medford to Greenville

Compare and see reviews for airlines that fly from Medford to Greenville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $360Free CancellationRating
7.4
9,706 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Medford to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from Medford.

Can I find flights from Medford to Greenville with flexible booking policies on momondo?

All flight searches from Medford to Greenville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Medford to Greenville?

Once all potential Medford to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Medford to Greenville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Medford to Greenville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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