What is the cheapest airline that flies from Medford to Greenville?

United Airlines, Alaska Airlines, and Delta are the most popular carriers operating from Medford to Greenville

What airlines fly to Greenville?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Greenville from Medford according to our data. United Airlines is the first choice among our users, with 64% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 3 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Medford Airport to Greenville Airport?

Prices for flights from Medford Airport to Greenville Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Medford Airport to Greenville Airport?

As of July 2025, there are 2 operators available to choose from for flights from Medford Airport to Greenville Airport.

How old do you have to be to fly from Medford Airport to Greenville Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Medford Airport to Greenville Airport.

What documentation or ID do you need to fly to Greenville Airport?

The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$131 Cheap Flights from Medford to Greenville in 2025

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Find the cheapest flights from Medford to Greenville

Round-trip

One-way

Cheap round-trip flights

6:15 am - 9:07 pmMFR-GSP

11h 52m2 stops

2:33 pm - 10:50 pmGSP-MFR

11h 17m2 stops

$315Delta

Find Deal

Tue, Sep 23 - Wed, Oct 1

6:15 am - 9:07 pmMFR-GSP

11h 52m2 stops

2:33 pm - 10:50 pmGSP-MFR

11h 17m2 stops

$344Delta

Find Deal

Tue, Sep 23 - Fri, Oct 3

5:00 am - 2:58 pmMFR-GSP

6h 58m1 stop

4:30 pm - 9:04 pmGSP-MFR

7h 34m1 stop

$351United Airlines

Find Deal

Sat, Aug 23 - Tue, Aug 26

5:00 pm - 9:13 amMFR-GSP

13h 13m2 stops

2:33 pm - 10:50 pmGSP-MFR

11h 17m2 stops

$355Delta

Find Deal

Fri, Sep 26 - Wed, Oct 1

5:00 am - 2:58 pmMFR-GSP

6h 58m1 stop

10:24 am - 9:04 pmGSP-MFR

13h 40m2 stops

$356United Airlines

Find Deal

Sat, Aug 23 - Tue, Aug 26

6:35 pm - 9:52 amMFR-GSP

12h 17m2 stops

4:25 pm - 9:26 pmGSP-MFR

8h 01m1 stop

$378United Airlines

Find Deal

Mon, Aug 11 - Mon, Aug 18

6:35 pm - 8:51 amMFR-GSP

11h 16m2 stops

4:29 pm - 9:06 pmGSP-MFR

7h 37m1 stop

$385United Airlines

Find Deal

Mon, Sep 22 - Tue, Sep 30

8:53 am - 10:25 pmMFR-GSP

10h 32m2 stops

7:34 am - 5:06 pmGSP-MFR

12h 32m2 stops

$524Alaska Airlines

Find Deal

Thu, Sep 25 - Fri, Oct 3

5:43 am - 7:42 pmMFR-GSP

10h 59m2 stops

7:36 am - 5:06 pmGSP-MFR

12h 30m2 stops

$575Alaska Airlines

Find Deal

Thu, Sep 25 - Tue, Sep 30

5:43 am - 7:42 pmMFR-GSP

10h 59m2 stops

12:27 pm - 12:33 amGSP-MFR

15h 06m2 stops

$679Alaska Airlines

Find Deal

Thu, Sep 25 - Thu, Oct 2

United Airlines flights from Medford to Greenville

Our best United Airlines deals on Medford to Greenville flight tickets

United Airlines

Aug 23

MFR5:00 amMedford

6h 58m

1 stop

GSP2:58 pmGreenville

Aug 26

GSP4:30 pmGreenville

7h 34m

1 stop

MFR9:04 pmMedford

$351

Find similar

United Airlines

Aug 23

MFR5:00 amMedford

6h 58m

1 stop

GSP2:58 pmGreenville

Aug 26

GSP10:24 amGreenville

13h 40m

2 stops

MFR9:04 pmMedford

$356

Find similar

United Airlines

Aug 11

MFR6:35 pmMedford

12h 17m

2 stops

GSP9:52 amGreenville

Aug 18

GSP4:25 pmGreenville

8h 01m

1 stop

MFR9:26 pmMedford

$378

Find similar

Delta flights from Medford to Greenville

Our best Delta deals on Medford to Greenville flight tickets

Delta

Sep 23

MFR6:15 amMedford

11h 52m

2 stops

GSP9:07 pmGreenville

Oct 1

GSP2:33 pmGreenville

11h 17m

2 stops

MFR10:50 pmMedford

$315

Find similar

Delta

Sep 23

MFR6:15 amMedford

11h 52m

2 stops

GSP9:07 pmGreenville

Oct 3

GSP2:33 pmGreenville

11h 17m

2 stops

MFR10:50 pmMedford

$344

Find similar

Delta

Sep 26

MFR5:00 pmMedford

13h 13m

2 stops

GSP9:13 amGreenville

Oct 1

GSP2:33 pmGreenville

11h 17m

2 stops

MFR10:50 pmMedford

$355

Find similar

How to get the cheapest flight ticket from Medford to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Greenville?

According to our data, Wednesday is the cheapest day to fly to Greenville from Medford. The lowest ticket price found for a Wednesday departure recently was $476. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $963. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the afternoon. Flights from Medford to Greenville during this time can be as low as $589. Flights to Greenville are more costly in the morning, with an average ticket price of $601. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Medford to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Medford to Greenville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Medford to Greenville (MFR to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to Greenville

Best Price Found	$131
Fastest flight time	6h 58m
Direct flights	None
Airports in Greenville	1 airport

The best one-way flight to Greenville from Medford in the past 72 hours is $131. The best round-trip flight deal from Medford to Greenville found on momondo in the last 72 hours is $315.

The fastest flight from Medford to Greenville takes 6h 58m

There are no direct flights from Medford to Greenville. Popular non-direct route for this connection is Medford Airport - Greenville Airport.

There is 1 airport near Greenville: Greenville (GSP)

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How far is Medford to Greenville by plane?
The distance between Medford and Greenville is about 2222.7 mi. By plane, this route typically takes 6h 58m.
When did momondo last update prices for flights from Medford Airport to Greenville Airport?
Prices for flights from Medford Airport to Greenville Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Medford Airport to Greenville Airport?
As of July 2025, there are 2 operators available to choose from for flights from Medford Airport to Greenville Airport.
How old do you have to be to fly from Medford Airport to Greenville Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Medford Airport to Greenville Airport.
What documentation or ID do you need to fly to Greenville Airport?
The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Medford to Greenville?
Based on momondo bookings for flights between Medford and Greenville, the leading airline is United Airlines, making up 72% of the total bookings. Other popular airlines include Delta with 28%.

Best airlines flying from Medford to Greenville

Compare and see reviews for airlines that fly from Medford to Greenville with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $254	Free Cancellation	Rating 7.4 8,863 reviews		Search United Airlines flights
Delta	PriceFrom $274	Free Cancellation	Rating 8.0 7,957 reviews		Search Delta flights

Anderson

Simpsonville

Greenwood

Seneca

Greer

Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Medford to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from Medford.

Can I find flights from Medford to Greenville with flexible booking policies on momondo?

All flight searches from Medford to Greenville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Medford to Greenville?

Once all potential Medford to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Medford to Greenville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Medford to Greenville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.