Cheap flights from Medford to Columbia from $339

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Medford to Columbia departing on 1/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

Find the cheapest flights from Medford to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:00 am - 6:55 pmMFR-CAE
10h 55m2 stops
United Airlines Logo
10:18 am - 11:09 pmCAE-MFR
15h 51m2 stops
$419United Airlines
Find Deal
Wed, Jan 7 - Tue, Apr 14
Delta Logo
5:20 pm - 9:30 amMFR-CAE
13h 10m2 stops
Delta Logo
5:10 pm - 11:41 pmCAE-MFR
9h 31m2 stops
$434Delta
Find Deal
Fri, Jan 9 - Tue, Apr 14
Delta Logo
12:07 pm - 9:30 amMFR-CAE
18h 23m2 stops
Delta Logo
5:10 pm - 11:41 pmCAE-MFR
9h 31m2 stops
$463Delta
Find Deal
Tue, Jan 6 - Tue, Apr 14
Delta Logo
5:20 pm - 9:30 amMFR-CAE
13h 10m2 stops
Delta Logo
6:50 pm - 4:47 pmCAE-MFR
24h 57m2 stops
$487Delta
Find Deal
Fri, Jan 9 - Wed, Apr 15
Delta Logo
3:00 pm - 9:30 amMFR-CAE
15h 30m2 stops
Delta Logo
5:10 pm - 11:41 pmCAE-MFR
9h 31m2 stops
$512Delta
Find Deal
Mon, Jan 5 - Tue, Apr 14
United Airlines Logo
5:00 am - 6:55 pmMFR-CAE
10h 55m2 stops
United Airlines Logo
7:35 pm - 5:50 pmCAE-MFR
25h 15m2 stops
$528United Airlines
Find Deal
Wed, Jan 7 - Sat, Apr 18
Delta Logo
12:07 pm - 9:30 amMFR-CAE
18h 23m2 stops
Delta Logo
5:10 pm - 11:41 pmCAE-MFR
9h 31m2 stops
$553Delta
Find Deal
Tue, Jan 6 - Wed, Apr 15
American Airlines Logo
5:20 am - 5:51 pmMFR-CAE
9h 31m2 stops
American Airlines Logo
2:33 pm - 10:49 pmCAE-MFR
11h 16m2 stops
$1,177American Airlines
Find Deal
Sat, Jan 3 - Wed, Apr 15
American Airlines Logo
5:20 am - 5:51 pmMFR-CAE
9h 31m2 stops
American Airlines Logo
2:33 pm - 10:49 pmCAE-MFR
11h 16m2 stops
$1,256American Airlines
Find Deal
Sat, Jan 3 - Fri, Apr 17
American Airlines Logo
5:20 am - 5:51 pmMFR-CAE
9h 31m2 stops
American Airlines Logo
4:16 pm - 10:49 pmCAE-MFR
9h 33m2 stops
$1,356American Airlines
Find Deal
Sat, Jan 3 - Mon, Apr 13

United Airlines flights from Medford to Columbia

Our best United Airlines deals on Medford to Columbia flight tickets
United Airlines
Jan 7
MFR5:00 amMedford
10h 55m
2 stops
CAE6:55 pmColumbia Metropolitan
Apr 14
CAE10:18 amColumbia Metropolitan
15h 51m
2 stops
MFR11:09 pmMedford
United Airlines
Jan 7
MFR6:25 pmMedford
16h 49m
2 stops
CAE2:14 pmColumbia Metropolitan
Apr 15
CAE5:25 pmColumbia Metropolitan
21h 09m
2 stops
MFR11:34 amMedford
United Airlines
Jan 4
MFR5:00 amMedford
26h 05m
2 stops
CAE10:05 amColumbia Metropolitan
Apr 14
CAE10:18 amColumbia Metropolitan
15h 51m
2 stops
MFR11:09 pmMedford

Delta flights from Medford to Columbia

Our best Delta deals on Medford to Columbia flight tickets
Delta
Jan 9
MFR5:20 pmMedford
13h 10m
2 stops
CAE9:30 amColumbia Metropolitan
Apr 14
CAE5:10 pmColumbia Metropolitan
9h 31m
2 stops
MFR11:41 pmMedford
Delta
Jan 6
MFR12:07 pmMedford
18h 23m
2 stops
CAE9:30 amColumbia Metropolitan
Apr 14
CAE5:10 pmColumbia Metropolitan
9h 31m
2 stops
MFR11:41 pmMedford
Delta
Jan 9
MFR5:20 pmMedford
13h 10m
2 stops
CAE9:30 amColumbia Metropolitan
Apr 15
CAE6:50 pmColumbia Metropolitan
24h 57m
2 stops
MFR4:47 pmMedford

momondo Fare Finder

 
Customize your flight search to find flights from Medford to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Medford to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Wed 1/7

5:00 am-6:55 pm

2 stops10h 55m

Columbia Metropolitan

Tue 4/14

10:18 am-11:09 pm

2 stops15h 51m

$419

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Fri 1/9

5:20 pm-9:30 am

2 stops13h 10m

Columbia Metropolitan

Tue 4/14

5:10 pm-11:41 pm

2 stops9h 31m

$434

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Tue 1/6

12:07 pm-9:30 am

2 stops18h 23m

Columbia Metropolitan

Tue 4/14

5:10 pm-11:41 pm

2 stops9h 31m

$463

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Fri 1/9

5:20 pm-9:30 am

2 stops13h 10m

Columbia Metropolitan

Wed 4/15

6:50 pm-4:47 pm

2 stops24h 57m

$487

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Mon 1/5

3:00 pm-9:30 am

2 stops15h 30m

Columbia Metropolitan

Tue 4/14

5:10 pm-11:41 pm

2 stops9h 31m

$512

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Wed 1/7

5:00 am-6:55 pm

2 stops10h 55m

Columbia Metropolitan

Sat 4/18

7:35 pm-5:50 pm

2 stops25h 15m

$528

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Tue 1/6

12:07 pm-9:30 am

2 stops18h 23m

Columbia Metropolitan

Wed 4/15

5:10 pm-11:41 pm

2 stops9h 31m

$553

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Sat 1/3

5:20 am-5:51 pm

2 stops9h 31m

Columbia Metropolitan

Wed 4/15

2:33 pm-10:49 pm

2 stops11h 16m

$1,177

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Sat 1/3

5:20 am-5:51 pm

2 stops9h 31m

Columbia Metropolitan

Fri 4/17

2:33 pm-10:49 pm

2 stops11h 16m

$1,256

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Sat 1/3

5:20 am-5:51 pm

2 stops9h 31m

Columbia Metropolitan

Mon 4/13

4:16 pm-10:49 pm

2 stops9h 33m

$1,356

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Columbia from

How to get the cheapest flight ticket from Medford to Columbia

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Medford to Columbia Metropolitan?

Delta, Alaska Airlines, and United Airlines are the most popular carriers operating from Medford to Columbia Metropolitan

What airlines fly to Columbia?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Columbia from Medford according to our data. United Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Columbia. Keep in mind that there are 4 different airlines that fly to Columbia on a routine basis, so you have a few additional options to choose from.

When to book flights from Medford to Columbia

Are you open to changing your travel dates? Check out the ideal times to fly from Medford to Columbia according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Medford to Columbia (MFR to CAE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to Columbia

Direct flights

None
There are no direct flights from Medford to Columbia. There are no popular flight routes from Medford to Columbia.
  • How far is Medford to Columbia Metropolitan by plane?

    A flight from Medford to Columbia Metropolitan will travel around 2318.2 mi. Typically, this will take 9h 31m by plane in normal conditions.

  • When did momondo last update prices for flights from Medford Airport to Columbia Metropolitan Airport?

    Prices for flights from Medford Airport to Columbia Metropolitan Airport refresh daily.

  • How old do you have to be to fly from Medford Airport to Columbia Metropolitan Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Medford Airport to Columbia Metropolitan Airport.

  • What documentation or ID do you need to fly to Columbia Metropolitan Airport?

    The travel and health documents you'll need for your trip to Columbia Metropolitan Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Columbia Metropolitan Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Orangeburg
Lexington
West Columbia
Irmo
Swansea

Why use momondo?

Why should I use momondo to find a flight deal from Medford to Columbia?

It is quick and easy to find Medford to Columbia flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Columbia that suits you.

Can I find flights from Medford to Columbia with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Columbia from Medford with this policy.

How can momondo help me find flights from Medford to Columbia?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Medford to Columbia.

I’m not ready to book a flight from Medford to Columbia right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Medford to Columbia flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Columbia trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 12/4
Thu 12/11

Find better results for your trip to the United States