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Cheap flights from Manchester, New Hampshire to St. Louis from $144

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to St. Louis departing on 11/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Manchester, New Hampshire to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:41 am - 1:18 pmMHT-STL
7h 37m1 stop
American Airlines Logo
6:00 pm - 11:57 pmSTL-MHT
4h 57m1 stop
$287American Airlines
Find Deal
Wed, Dec 3 - Tue, Dec 9
Southwest Logo
5:50 am - 9:40 amMHT-STL
4h 50m1 stop
Southwest Logo
8:15 am - 4:35 pmSTL-MHT
7h 20m2 stops
$312Southwest
Find Deal
Sat, Dec 13 - Tue, Dec 16
Southwest Logo
5:20 pm - 11:15 pmMHT-STL
6h 55m1 stop
Southwest Logo
1:50 pm - 9:05 pmSTL-MHT
6h 15m1 stop
$347Southwest
Find Deal
Fri, Dec 12 - Tue, Dec 16
American Airlines Logo
5:16 pm - 9:47 pmMHT-STL
5h 31m1 stop
American Airlines Logo
5:15 am - 4:43 pmSTL-MHT
10h 28m2 stops
$350American Airlines
Find Deal
Wed, Dec 3 - Tue, Dec 9
Southwest Logo
12:30 pm - 7:35 pmMHT-STL
8h 05m2 stops
Southwest Logo
6:05 am - 12:20 pmSTL-MHT
5h 15m1 stop
$352Southwest
Find Deal
Fri, Dec 12 - Tue, Dec 16
Southwest Logo
2:40 pm - 6:30 pmMHT-STL
4h 50m1 stop
Southwest Logo
7:45 am - 2:55 pmSTL-MHT
6h 10m1 stop
$364Southwest
Find Deal
Fri, Oct 31 - Mon, Nov 3
American Airlines Logo
6:00 am - 10:17 amMHT-STL
5h 17m1 stop
American Airlines Logo
7:12 am - 3:55 pmSTL-MHT
7h 43m1 stop
$367American Airlines
Find Deal
Thu, Dec 11 - Sun, Dec 14
United Airlines Logo
2:33 pm - 9:00 pmMHT-STL
7h 27m2 stops
United Airlines Logo
7:41 am - 6:53 pmSTL-MHT
10h 12m2 stops
$377United Airlines
Find Deal
Tue, Feb 24 - Wed, Feb 25
United Airlines Logo
2:33 pm - 9:00 pmMHT-STL
7h 27m2 stops
United Airlines Logo
8:30 am - 1:58 pmSTL-MHT
4h 28m1 stop
$392United Airlines
Find Deal
Tue, Feb 24 - Wed, Feb 25
United Airlines Logo
2:32 pm - 11:42 pmMHT-STL
10h 10m2 stops
United Airlines Logo
10:00 am - 6:49 pmSTL-MHT
7h 49m2 stops
$417United Airlines
Find Deal
Wed, Dec 3 - Tue, Dec 9

Southwest flights from Manchester, New Hampshire to St. Louis

Our best Southwest deals on Manchester, New Hampshire to St. Louis flight tickets
Southwest
Dec 13
MHT5:50 amManchester
4h 50m
1 stop
STL9:40 amLambert-St Louis
Dec 16
STL8:15 amLambert-St Louis
7h 20m
2 stops
MHT4:35 pmManchester
$312
Find similar
Southwest
Dec 12
MHT5:20 pmManchester
6h 55m
1 stop
STL11:15 pmLambert-St Louis
Dec 16
STL1:50 pmLambert-St Louis
6h 15m
1 stop
MHT9:05 pmManchester
$347
Find similar
Southwest
Dec 12
MHT12:30 pmManchester
8h 05m
2 stops
STL7:35 pmLambert-St Louis
Dec 16
STL6:05 amLambert-St Louis
5h 15m
1 stop
MHT12:20 pmManchester
$352
Find similar

American Airlines flights from Manchester, New Hampshire to St. Louis

Our best American Airlines deals on Manchester, New Hampshire to St. Louis flight tickets
American Airlines
Dec 3
MHT6:41 amManchester
7h 37m
1 stop
STL1:18 pmLambert-St Louis
Dec 9
STL6:00 pmLambert-St Louis
4h 57m
1 stop
MHT11:57 pmManchester
$287
Find similar
American Airlines
Dec 3
MHT5:16 pmManchester
5h 31m
1 stop
STL9:47 pmLambert-St Louis
Dec 9
STL5:15 amLambert-St Louis
10h 28m
2 stops
MHT4:43 pmManchester
$350
Find similar
American Airlines
Dec 11
MHT6:00 amManchester
5h 17m
1 stop
STL10:17 amLambert-St Louis
Dec 14
STL7:12 amLambert-St Louis
7h 43m
1 stop
MHT3:55 pmManchester
$367
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 12/3

6:41 am-1:18 pm

1 stop7h 37m

Lambert-St Louis

Tue 12/9

6:00 pm-11:57 pm

1 stop4h 57m

$287

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Sat 12/13

5:50 am-9:40 am

1 stop4h 50m

Lambert-St Louis

Tue 12/16

8:15 am-4:35 pm

2 stops7h 20m

$312

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Fri 12/12

5:20 pm-11:15 pm

1 stop6h 55m

Lambert-St Louis

Tue 12/16

1:50 pm-9:05 pm

1 stop6h 15m

$347

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 12/3

5:16 pm-9:47 pm

1 stop5h 31m

Lambert-St Louis

Tue 12/9

5:15 am-4:43 pm

2 stops10h 28m

$350

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Fri 12/12

12:30 pm-7:35 pm

2 stops8h 05m

Lambert-St Louis

Tue 12/16

6:05 am-12:20 pm

1 stop5h 15m

$352

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Fri 10/31

2:40 pm-6:30 pm

1 stop4h 50m

Lambert-St Louis

Mon 11/3

7:45 am-2:55 pm

1 stop6h 10m

$364

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Thu 12/11

6:00 am-10:17 am

1 stop5h 17m

Lambert-St Louis

Sun 12/14

7:12 am-3:55 pm

1 stop7h 43m

$367

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 2/24

2:33 pm-9:00 pm

2 stops7h 27m

Lambert-St Louis

Wed 2/25

7:41 am-6:53 pm

2 stops10h 12m

$377

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 2/24

2:33 pm-9:00 pm

2 stops7h 27m

Lambert-St Louis

Wed 2/25

8:30 am-1:58 pm

1 stop4h 28m

$392

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 12/3

2:32 pm-11:42 pm

2 stops10h 10m

Lambert-St Louis

Tue 12/9

10:00 am-6:49 pm

2 stops7h 49m

$417

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Manchester, New Hampshire to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, September is the cheapest month to fly from Manchester, New Hampshire to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $326. The month of August is another great option to travel to St. Louis, with average flight prices from Manchester, New Hampshire averaging around $370.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Wednesday when prices can be found for as low as $426. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $501. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Manchester, New Hampshire in the evening is the least expensive time of day to depart. momondo users have found prices as low as $432 when looking at flights departing in the evening. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $454 per ticket.

Can stopping save me money on Manchester, New Hampshire to St. Louis flights?

You could potentially save up to 8% on your flight if you consider stops on a Manchester, New Hampshire to St. Louis flight.

How have Manchester, New Hampshire to St. Louis flight prices changed over time?

As of October 2025, prices for Manchester, New Hampshire to St. Louis flights are approximately 31% more expensive when compared to flights at the same time last year.

When to book flights from Manchester, New Hampshire to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to St. Louis (MHT to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to St. Louis

Direct flights

None
There are no direct flights from Manchester, New Hampshire to St. Louis. There are no popular flight routes from Manchester, New Hampshire to St. Louis.
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  • How far is Manchester to Lambert-St Louis by plane?

    Manchester and Lambert-St Louis are 1022.3 mi apart from one another. Flights usually cover this in 4h 50m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Manchester Airport to Lambert-St Louis Airport?

    Prices for flights from Manchester Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Manchester Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Manchester Airport to Lambert-St Louis Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Manchester Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents you'll need for your trip to Lambert-St Louis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Lambert-St Louis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester, New Hampshire to St. Louis?

Best airlines flying from Manchester, New Hampshire to St. Louis

Compare and see reviews for airlines that fly from Manchester, New Hampshire to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $264Free CancellationRating
8.0
4,241 reviews
Search Southwest flights
American AirlinesPriceFrom $278Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
Wentzville
Collinsville
Fenton
St. Peters
Alton
Farmington
Festus
Glencoe
Clayton
Edwardsville
Eureka
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to St. Louis?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to St. Louis from Manchester.

Can I find flights from Manchester to St. Louis with flexible booking policies on momondo?

momondo does allow users to show only those flights to St. Louis from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to St. Louis?

momondo provides multiple filters to help you find the best flight to St. Louis from Manchester. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Manchester to St. Louis right now. Can momondo alert me if prices change?

Price alerts on flights to St. Louis from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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