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Cheap flights from Manchester, New Hampshire to St. Louis from $287

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to St. Louis departing on 1/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Manchester, New Hampshire to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:01 pm - 9:51 pm
MHT
-
STL
5h 50m1 stop
American Airlines Logo
6:00 am - 11:50 am
STL
-
MHT
4h 50m1 stop
$287American Airlines
Wed, Jan 7 - Sat, Jan 10
American Airlines Logo
5:01 pm - 9:51 pm
MHT
-
STL
5h 50m1 stop
American Airlines Logo
6:52 am - 1:17 pm
STL
-
MHT
5h 25m1 stop
$325American Airlines
Tue, Jan 20 - Fri, Jan 23
Southwest Logo
5:55 am - 12:45 pm
MHT
-
STL
7h 50m2 stops
Southwest Logo
2:45 pm - 10:10 pm
STL
-
MHT
6h 25m1 stop
$328Southwest
Wed, Jan 7 - Sat, Jan 10
American Airlines Logo
5:01 pm - 9:51 pm
MHT
-
STL
5h 50m1 stop
American Airlines Logo
3:54 pm - 11:46 pm
STL
-
MHT
6h 52m1 stop
$347American Airlines
Fri, Feb 6 - Tue, Feb 10
Southwest Logo
12:45 pm - 7:00 pm
MHT
-
STL
7h 15m1 stop
Southwest Logo
2:15 pm - 10:05 pm
STL
-
MHT
6h 50m2 stops
$350Southwest
Tue, Jan 20 - Fri, Jan 23
American Airlines Logo
4:06 pm - 10:44 pm
MHT
-
STL
7h 38m1 stop
American Airlines Logo
3:54 pm - 11:46 pm
STL
-
MHT
6h 52m1 stop
$357American Airlines
Wed, Jan 7 - Fri, Jan 9
Southwest Logo
12:45 pm - 7:00 pm
MHT
-
STL
7h 15m1 stop
Southwest Logo
1:45 pm - 11:05 pm
STL
-
MHT
8h 20m1 stop
$359Southwest
Thu, Jan 8 - Mon, Jan 12
Southwest Logo
12:45 pm - 9:00 pm
MHT
-
STL
9h 15m2 stops
Southwest Logo
6:50 am - 12:10 pm
STL
-
MHT
4h 20m1 stop
$364Southwest
Thu, Jan 8 - Mon, Jan 12
Southwest Logo
3:25 pm - 9:55 pm
MHT
-
STL
7h 30m2 stops
Southwest Logo
10:25 am - 5:30 pm
STL
-
MHT
6h 05m2 stops
$369Southwest
Wed, Jan 7 - Sat, Jan 10
United Airlines Logo
2:17 pm - 10:58 pm
MHT
-
STL
9h 41m2 stops
United Airlines Logo
12:44 pm - 6:51 pm
STL
-
MHT
5h 07m1 stop
$372United Airlines
Wed, Jan 7 - Sat, Jan 10

American Airlines flights from Manchester, New Hampshire to St. Louis

Our best American Airlines deals on Manchester, New Hampshire to St. Louis flight tickets
American Airlines
Jan 7
MHT12:08 pmManchester
6h 15m
1 stop
STL5:23 pmLambert-St Louis
Jan 10
STL9:54 amLambert-St Louis
5h 38m
1 stop
MHT4:32 pmManchester
$287
Find similar
American Airlines
Feb 6
MHT5:01 pmManchester
5h 50m
1 stop
STL9:51 pmLambert-St Louis
Feb 10
STL3:54 pmLambert-St Louis
6h 52m
1 stop
MHT11:46 pmManchester
$347
Find similar
American Airlines
Apr 27
MHT5:47 amManchester
4h 53m
1 stop
STL9:40 amLambert-St Louis
Apr 29
STL6:28 amLambert-St Louis
4h 10m
1 stop
MHT11:38 amManchester
$377
Find similar

Southwest flights from Manchester, New Hampshire to St. Louis

Our best Southwest deals on Manchester, New Hampshire to St. Louis flight tickets
Southwest
Jan 7
MHT5:55 amManchester
7h 50m
2 stops
STL12:45 pmLambert-St Louis
Jan 10
STL2:45 pmLambert-St Louis
6h 25m
1 stop
MHT10:10 pmManchester
$328
Find similar
Southwest
Jan 7
MHT3:25 pmManchester
7h 30m
2 stops
STL9:55 pmLambert-St Louis
Jan 10
STL10:25 amLambert-St Louis
6h 05m
2 stops
MHT5:30 pmManchester
$369
Find similar
Southwest
Mar 26
MHT5:35 amManchester
6h 15m
1 stop
STL10:50 amLambert-St Louis
Mar 30
STL2:15 pmLambert-St Louis
8h 50m
2 stops
MHT12:05 amManchester
$412
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 14, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 1/7

5:01 pm-9:51 pm

1 stop5h 50m

Lambert-St Louis

Sat 1/10

6:00 am-11:50 am

1 stop4h 50m

$287

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 1/20

5:01 pm-9:51 pm

1 stop5h 50m

Lambert-St Louis

Fri 1/23

6:52 am-1:17 pm

1 stop5h 25m

$325

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 1/7

5:55 am-12:45 pm

2 stops7h 50m

Lambert-St Louis

Sat 1/10

2:45 pm-10:10 pm

1 stop6h 25m

$328

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Fri 2/6

5:01 pm-9:51 pm

1 stop5h 50m

Lambert-St Louis

Tue 2/10

3:54 pm-11:46 pm

1 stop6h 52m

$347

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 1/20

12:45 pm-7:00 pm

1 stop7h 15m

Lambert-St Louis

Fri 1/23

2:15 pm-10:05 pm

2 stops6h 50m

$350

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 1/7

4:06 pm-10:44 pm

1 stop7h 38m

Lambert-St Louis

Fri 1/9

3:54 pm-11:46 pm

1 stop6h 52m

$357

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Thu 1/8

12:45 pm-7:00 pm

1 stop7h 15m

Lambert-St Louis

Mon 1/12

1:45 pm-11:05 pm

1 stop8h 20m

$359

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Thu 1/8

12:45 pm-9:00 pm

2 stops9h 15m

Lambert-St Louis

Mon 1/12

6:50 am-12:10 pm

1 stop4h 20m

$364

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 1/7

3:25 pm-9:55 pm

2 stops7h 30m

Lambert-St Louis

Sat 1/10

10:25 am-5:30 pm

2 stops6h 05m

$369

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 1/7

2:17 pm-10:58 pm

2 stops9h 41m

Lambert-St Louis

Sat 1/10

12:44 pm-6:51 pm

1 stop5h 07m

$372

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Manchester, New Hampshire to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Manchester, New Hampshire and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, September is the cheapest month to fly from Manchester, New Hampshire to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $326. The month of November is another great option to travel to St. Louis, with average flight prices from Manchester, New Hampshire averaging around $356.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Wednesday when prices can be found for as low as $421. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $499. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Manchester, New Hampshire in the evening is the least expensive time of day to depart. momondo users have found prices as low as $433 when looking at flights departing in the evening. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $457 per ticket.

Can stopping save me money on Manchester, New Hampshire to St. Louis flights?

You could potentially save up to 2% on your flight if you consider stops on a Manchester, New Hampshire to St. Louis flight.

How have Manchester, New Hampshire to St. Louis flight prices changed over time?

As of December 2025, prices for Manchester, New Hampshire to St. Louis flights are approximately 59% cheaper when compared to flights at the same time last year.

When to book flights from Manchester, New Hampshire to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to St. Louis (MHT to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to St. Louis

Fastest flight time

4h 35m

Direct flights

None
The fastest flight from Manchester, New Hampshire to St. Louis takes 4h 35m
There are no direct flights from Manchester, New Hampshire to St. Louis. There are no popular flight routes from Manchester, New Hampshire to St. Louis.
Search flight deals

  • How far is Manchester to Lambert-St Louis by plane?

    Manchester and Lambert-St Louis are 1022.3 mi apart from one another. Flights usually cover this in 4h 35m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Manchester Airport to Lambert-St Louis Airport?

    Prices for flights from Manchester Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Manchester Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Manchester Airport to Lambert-St Louis Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Manchester Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents you'll need for your trip to Lambert-St Louis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Lambert-St Louis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester, New Hampshire to St. Louis?

Best airlines flying from Manchester, New Hampshire to St. Louis

Compare and see reviews for airlines that fly from Manchester, New Hampshire to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $264Free CancellationRating
7.9
4,251 reviews
Search Southwest flights
American AirlinesPriceFrom $274Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
O'Fallon
Florissant
Fenton
Wentzville
St. Peters
Collinsville
Alton
Farmington
Festus
Clayton
Glencoe
Edwardsville
Eureka
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to St. Louis?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to St. Louis from Manchester.

Can I find flights from Manchester to St. Louis with flexible booking policies on momondo?

momondo does allow users to show only those flights to St. Louis from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to St. Louis?

momondo provides multiple filters to help you find the best flight to St. Louis from Manchester. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Manchester to St. Louis right now. Can momondo alert me if prices change?

Price alerts on flights to St. Louis from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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