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Cheap flights from Manchester, New Hampshire to St. Louis from $154

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to St. Louis departing on 4/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Manchester, New Hampshire to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:44 am - 9:37 am
MHT
-
STL
4h 53m
1 stop
American Airlines Logo
3:43 pm - 11:44 pm
STL
-
MHT
7h 01m
1 stop
$307American Airlines
Wed, Apr 15 - Tue, Apr 28
Southwest Logo
5:35 am - 12:50 pm
MHT
-
STL
8h 15m
2 stops
Southwest Logo
6:35 am - 12:10 pm
STL
-
MHT
4h 35m
1 stop
$312Southwest
Wed, May 6 - Wed, May 13
United Airlines Logo
2:36 pm - 11:57 pm
MHT
-
STL
10h 21m
2 stops
United Airlines Logo
9:21 am - 6:56 pm
STL
-
MHT
8h 35m
2 stops
$317United Airlines
Tue, May 5 - Wed, May 6
United Airlines Logo
2:36 pm - 7:27 pm
MHT
-
STL
5h 51m
1 stop
United Airlines Logo
9:21 am - 6:56 pm
STL
-
MHT
8h 35m
2 stops
$332United Airlines
Sat, May 2 - Tue, May 5
Southwest Logo
7:30 am - 11:30 am
MHT
-
STL
5h 00m
1 stop
Southwest Logo
3:55 pm - 9:05 pm
STL
-
MHT
4h 10m
1 stop
$335Southwest
Tue, Jun 2 - Wed, Jun 3
United Airlines Logo
2:36 pm - 10:45 pm
MHT
-
STL
9h 09m
2 stops
United Airlines Logo
7:45 am - 6:56 pm
STL
-
MHT
10h 11m
2 stops
$337United Airlines
Sat, May 2 - Tue, May 5
Southwest Logo
7:30 am - 11:30 am
MHT
-
STL
5h 00m
1 stop
Southwest Logo
2:30 pm - 10:30 pm
STL
-
MHT
7h 00m
2 stops
$340Southwest
Tue, Jun 2 - Wed, Jun 3
Southwest Logo
12:45 pm - 8:00 pm
MHT
-
STL
8h 15m
2 stops
Southwest Logo
2:30 pm - 10:30 pm
STL
-
MHT
7h 00m
2 stops
$345Southwest
Tue, Jun 2 - Wed, Jun 3
American Airlines Logo
5:07 pm - 10:07 pm
MHT
-
STL
6h 00m
1 stop
American Airlines Logo
6:00 am - 11:36 am
STL
-
MHT
4h 36m
1 stop
$346American Airlines
Mon, Apr 27 - Wed, Apr 29
American Airlines Logo
5:41 pm - 10:17 pm
MHT
-
STL
5h 36m
1 stop
American Airlines Logo
5:51 am - 11:42 am
STL
-
MHT
4h 51m
1 stop
$356American Airlines
Mon, Apr 27 - Wed, Apr 29

American Airlines flights from Manchester, New Hampshire to St. Louis

Our best American Airlines deals on Manchester, New Hampshire to St. Louis flight tickets
American Airlines
Apr 15
MHT5:44 amManchester
4h 53m
1 stop
STL9:37 amLambert-St Louis
Apr 28
STL3:43 pmLambert-St Louis
7h 01m
1 stop
MHT11:44 pmManchester
$307
American Airlines
Apr 27
MHT5:07 pmManchester
6h 00m
1 stop
STL10:07 pmLambert-St Louis
Apr 29
STL6:00 amLambert-St Louis
4h 36m
1 stop
MHT11:36 amManchester
$346
American Airlines
Apr 27
MHT5:41 pmManchester
5h 36m
1 stop
STL10:17 pmLambert-St Louis
Apr 29
STL5:51 amLambert-St Louis
4h 51m
1 stop
MHT11:42 amManchester
$356

Southwest flights from Manchester, New Hampshire to St. Louis

Our best Southwest deals on Manchester, New Hampshire to St. Louis flight tickets
Southwest
May 16
MHT12:25 pmManchester
7h 45m
2 stops
STL7:10 pmLambert-St Louis
May 20
STL6:35 amLambert-St Louis
4h 35m
1 stop
MHT12:10 pmManchester
$312
Southwest
Apr 8
MHT1:45 pmManchester
9h 50m
1 stop
STL10:35 pmLambert-St Louis
Apr 9
STL5:00 amLambert-St Louis
6h 35m
1 stop
MHT12:35 pmManchester
$360
Southwest
Apr 13
MHT3:15 pmManchester
8h 40m
2 stops
STL10:55 pmLambert-St Louis
Apr 15
STL1:45 pmLambert-St Louis
6h 20m
1 stop
MHT9:05 pmManchester
$361

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from Manchester, New Hampshire to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 4/15

5:44 am-9:37 am

1 stop4h 53m

Lambert-St Louis

Tue 4/28

3:43 pm-11:44 pm

1 stop7h 01m

$307

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 5/6

5:35 am-12:50 pm

2 stops8h 15m

Lambert-St Louis

Wed 5/13

6:35 am-12:10 pm

1 stop4h 35m

$312

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 5/5

2:36 pm-11:57 pm

2 stops10h 21m

Lambert-St Louis

Wed 5/6

9:21 am-6:56 pm

2 stops8h 35m

$317

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Sat 5/2

2:36 pm-7:27 pm

1 stop5h 51m

Lambert-St Louis

Tue 5/5

9:21 am-6:56 pm

2 stops8h 35m

$332
Quickest round-trip

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 6/2

7:30 am-11:30 am

1 stop5h 00m

Lambert-St Louis

Wed 6/3

3:55 pm-9:05 pm

1 stop4h 10m

$335

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Sat 5/2

2:36 pm-10:45 pm

2 stops9h 09m

Lambert-St Louis

Tue 5/5

7:45 am-6:56 pm

2 stops10h 11m

$337

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 6/2

7:30 am-11:30 am

1 stop5h 00m

Lambert-St Louis

Wed 6/3

2:30 pm-10:30 pm

2 stops7h 00m

$340

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 6/2

12:45 pm-8:00 pm

2 stops8h 15m

Lambert-St Louis

Wed 6/3

2:30 pm-10:30 pm

2 stops7h 00m

$345

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Mon 4/27

5:07 pm-10:07 pm

1 stop6h 00m

Lambert-St Louis

Wed 4/29

6:00 am-11:36 am

1 stop4h 36m

$346

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Mon 4/27

5:41 pm-10:17 pm

1 stop5h 36m

Lambert-St Louis

Wed 4/29

5:51 am-11:42 am

1 stop4h 51m

$356

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Manchester, New Hampshire to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, February is the cheapest month to fly from Manchester, New Hampshire to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $323. The month of September is another great option to travel to St. Louis, with average flight prices from Manchester, New Hampshire averaging around $326.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Wednesday when prices can be found for as low as $421. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $486. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Manchester, New Hampshire in the evening is the least expensive time of day to depart. momondo users have found prices as low as $424 when looking at flights departing in the evening. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $468 per ticket.

Can stopping save me money on Manchester, New Hampshire to St. Louis flights?

You could potentially save up to 49% on your flight if you consider stops on a Manchester, New Hampshire to St. Louis flight.

When to book flights from Manchester, New Hampshire to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to St. Louis (MHT to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to St. Louis

Fastest flight time

4h 35m

Direct flights

None
The fastest flight from Manchester, New Hampshire to St. Louis takes 4h 35m
There are no direct flights from Manchester, New Hampshire to St. Louis. There are no popular flight routes from Manchester, New Hampshire to St. Louis.
Search flight deals

  • How far is Manchester to Lambert-St Louis by plane?

    Manchester and Lambert-St Louis are 1022.3 mi apart from one another. Flights usually cover this in 4h 35m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Manchester Airport to Lambert-St Louis Airport?

    Prices for flights from Manchester Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Manchester Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Manchester Airport to Lambert-St Louis Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Manchester Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents you'll need for your trip to Lambert-St Louis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Lambert-St Louis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester, New Hampshire to St. Louis?

Best airlines flying from Manchester, New Hampshire to St. Louis

Compare and see reviews for airlines that fly from Manchester, New Hampshire to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $200Free CancellationRating
8.0
4,318 reviews
Search Southwest flights
American AirlinesPriceFrom $278Free CancellationRating
7.1
11,446 reviews
Search American Airlines flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
Collinsville
St. Peters
Fenton
Alton
Wentzville
Farmington
Edwardsville
Festus
Clayton
Eureka
Litchfield
Glencoe
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to St. Louis?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to St. Louis from Manchester.

Can I find flights from Manchester to St. Louis with flexible booking policies on momondo?

momondo does allow users to show only those flights to St. Louis from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to St. Louis?

momondo provides multiple filters to help you find the best flight to St. Louis from Manchester. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Manchester to St. Louis right now. Can momondo alert me if prices change?

Price alerts on flights to St. Louis from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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