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Cheap flights from Manchester, New Hampshire to Panama City from $170

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Panama City departing on 8/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Manchester, New Hampshire to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 11:23 amMHT  Manchester-ECP Panama City NW Florida Beaches
6h 23m1 stop Washington, D.C. Reagan-National
American Airlines Logo
1:32 pm - 9:55 pmECP  Panama City NW Florida Beaches-MHT Manchester
7h 23m1 stop Charlotte Douglas
$362American Airlines
Tue, Sep 1 - Tue, Sep 15
Southwest Logo
5:35 am - 3:00 pmMHT  Manchester-ECP Panama City NW Florida Beaches
10h 25m2 stops Baltimore/Washington Nashville Intl
Southwest Logo
10:30 am - 9:55 pmECP  Panama City NW Florida Beaches-MHT Manchester
10h 25m2 stops Austin Bergstrom Baltimore/Washington
$385Southwest
Tue, Sep 1 - Tue, Sep 15
American Airlines Logo
7:05 am - 11:12 amMHT  Manchester-ECP Panama City NW Florida Beaches
5h 07m1 stop Charlotte Douglas
American Airlines Logo
1:15 pm - 10:05 pmECP  Panama City NW Florida Beaches-MHT Manchester
7h 50m1 stop Philadelphia
$392American Airlines
Tue, Sep 1 - Tue, Sep 8
Southwest Logo
11:55 am - 6:10 pmMHT  Manchester-ECP Panama City NW Florida Beaches
7h 15m2 stops Baltimore/Washington Lambert-St Louis
Southwest Logo
11:30 am - 9:55 pmECP  Panama City NW Florida Beaches-MHT Manchester
9h 25m2 stops Nashville Intl Baltimore/Washington
$395Southwest
Sat, Sep 19 - Wed, Sep 23
Southwest Logo
5:45 am - 1:55 pmMHT  Manchester-ECP Panama City NW Florida Beaches
9h 10m1 stop Baltimore/Washington
Southwest Logo
11:30 am - 9:55 pmECP  Panama City NW Florida Beaches-MHT Manchester
9h 25m2 stops Nashville Intl Baltimore/Washington
$396Southwest
Sat, Sep 19 - Wed, Sep 23
American Airlines Logo
6:00 am - 1:03 pmMHT  Manchester-ECP Panama City NW Florida Beaches
8h 03m1 stop Washington, D.C. Reagan-National
American Airlines Logo
7:10 am - 1:57 pmECP  Panama City NW Florida Beaches-MHT Manchester
5h 47m1 stop Charlotte Douglas
$411American Airlines
Thu, Nov 12 - Sun, Nov 15
American Airlines Logo
6:00 am - 11:22 amMHT  Manchester-ECP Panama City NW Florida Beaches
6h 22m1 stop Washington, D.C. Reagan-National
American Airlines Logo
8:29 am - 4:14 pmECP  Panama City NW Florida Beaches-MHT Manchester
6h 45m1 stop Charlotte Douglas
$415American Airlines
Sat, Sep 26 - Tue, Sep 29
American Airlines Logo
11:25 am - 5:16 pmMHT  Manchester-ECP Panama City NW Florida Beaches
6h 51m1 stop Charlotte Douglas
American Airlines Logo
1:15 pm - 10:05 pmECP  Panama City NW Florida Beaches-MHT Manchester
7h 50m1 stop Philadelphia
$428American Airlines
Wed, Aug 19 - Thu, Aug 20
Southwest Logo
5:45 am - 2:05 pmMHT  Manchester-ECP Panama City NW Florida Beaches
9h 20m2 stops Baltimore/Washington Lambert-St Louis
Southwest Logo
11:30 am - 9:15 pmECP  Panama City NW Florida Beaches-MHT Manchester
8h 45m2 stops Nashville Intl Chicago Midway
$441Southwest
Sat, Sep 26 - Tue, Sep 29
Southwest Logo
5:45 am - 1:55 pmMHT  Manchester-ECP Panama City NW Florida Beaches
9h 10m1 stop Baltimore/Washington
Southwest Logo
7:45 am - 5:35 pmECP  Panama City NW Florida Beaches-MHT Manchester
8h 50m2 stops Nashville Intl Baltimore/Washington
$442Southwest
Sat, Sep 26 - Tue, Sep 29

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American Airlines flights from Manchester, New Hampshire to Panama City, Florida

Our best American Airlines deals on Manchester, New Hampshire to Panama City, Florida flight tickets
American Airlines
Sep 1
MHT6:00 amManchester
6h 23m
1 stop
ECP11:23 amPanama City NW Florida Beaches
Sep 15
ECP1:32 pmPanama City NW Florida Beaches
7h 23m
1 stop
MHT9:55 pmManchester
$362
American Airlines
Sep 1
MHT7:05 amManchester
5h 07m
1 stop
ECP11:12 amPanama City NW Florida Beaches
Sep 8
ECP1:15 pmPanama City NW Florida Beaches
7h 50m
1 stop
MHT10:05 pmManchester
$392
American Airlines
Nov 12
MHT6:00 amManchester
8h 03m
1 stop
ECP1:03 pmPanama City NW Florida Beaches
Nov 15
ECP7:10 amPanama City NW Florida Beaches
5h 47m
1 stop
MHT1:57 pmManchester
$411

Southwest flights from Manchester, New Hampshire to Panama City, Florida

Our best Southwest deals on Manchester, New Hampshire to Panama City, Florida flight tickets
Southwest
Sep 1
MHT5:35 amManchester
10h 25m
2 stops
ECP3:00 pmPanama City NW Florida Beaches
Sep 15
ECP10:30 amPanama City NW Florida Beaches
10h 25m
2 stops
MHT9:55 pmManchester
$385
Southwest
Sep 19
MHT11:55 amManchester
7h 15m
2 stops
ECP6:10 pmPanama City NW Florida Beaches
Sep 23
ECP11:30 amPanama City NW Florida Beaches
9h 25m
2 stops
MHT9:55 pmManchester
$395
Southwest
Sep 19
MHT5:45 amManchester
9h 10m
1 stop
ECP1:55 pmPanama City NW Florida Beaches
Sep 23
ECP11:30 amPanama City NW Florida Beaches
9h 25m
2 stops
MHT9:55 pmManchester
$396

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from Manchester, New Hampshire to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ManchesterPanama City

MHT Manchester - ECP Panama City NW Florida Beaches

MHTECP

Manchester

Tue 9/1

6:00 am-11:23 am

1 stop6h 23m

Panama City NW Florida Beaches

Tue 9/15

1:32 pm-9:55 pm

1 stop7h 23m

$362

ManchesterPanama City

MHT Manchester - ECP Panama City NW Florida Beaches

MHTECP

Manchester

Tue 9/1

5:35 am-3:00 pm

2 stops10h 25m

Panama City NW Florida Beaches

Tue 9/15

10:30 am-9:55 pm

2 stops10h 25m

$385
Quickest round-trip

ManchesterPanama City

MHT Manchester - ECP Panama City NW Florida Beaches

MHTECP

Manchester

Tue 9/1

7:05 am-11:12 am

1 stop5h 07m

Panama City NW Florida Beaches

Tue 9/8

1:15 pm-10:05 pm

1 stop7h 50m

$392

ManchesterPanama City

MHT Manchester - ECP Panama City NW Florida Beaches

MHTECP

Manchester

Sat 9/19

11:55 am-6:10 pm

2 stops7h 15m

Panama City NW Florida Beaches

Wed 9/23

11:30 am-9:55 pm

2 stops9h 25m

$395

ManchesterPanama City

MHT Manchester - ECP Panama City NW Florida Beaches

MHTECP

Manchester

Sat 9/19

5:45 am-1:55 pm

1 stop9h 10m

Panama City NW Florida Beaches

Wed 9/23

11:30 am-9:55 pm

2 stops9h 25m

$396

ManchesterPanama City

MHT Manchester - ECP Panama City NW Florida Beaches

MHTECP

Manchester

Thu 11/12

6:00 am-1:03 pm

1 stop8h 03m

Panama City NW Florida Beaches

Sun 11/15

7:10 am-1:57 pm

1 stop5h 47m

$411

ManchesterPanama City

MHT Manchester - ECP Panama City NW Florida Beaches

MHTECP

Manchester

Sat 9/26

6:00 am-11:22 am

1 stop6h 22m

Panama City NW Florida Beaches

Tue 9/29

8:29 am-4:14 pm

1 stop6h 45m

$415

ManchesterPanama City

MHT Manchester - ECP Panama City NW Florida Beaches

MHTECP

Manchester

Wed 8/19

11:25 am-5:16 pm

1 stop6h 51m

Panama City NW Florida Beaches

Thu 8/20

1:15 pm-10:05 pm

1 stop7h 50m

$428

ManchesterPanama City

MHT Manchester - ECP Panama City NW Florida Beaches

MHTECP

Manchester

Sat 9/26

5:45 am-2:05 pm

2 stops9h 20m

Panama City NW Florida Beaches

Tue 9/29

11:30 am-9:15 pm

2 stops8h 45m

$441

ManchesterPanama City

MHT Manchester - ECP Panama City NW Florida Beaches

MHTECP

Manchester

Sat 9/26

5:45 am-1:55 pm

1 stop9h 10m

Panama City NW Florida Beaches

Tue 9/29

7:45 am-5:35 pm

2 stops8h 50m

$442

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Manchester, New Hampshire to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Manchester, New Hampshire is in February. Flight prices, which tend to average around $406, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Panama City, Florida, with average flight prices from Manchester, New Hampshire averaging around $407.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Thursday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $523. On the other hand, Saturday is the most expensive day to depart from Manchester, New Hampshire because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,849.

Can stopping save me money on Manchester, New Hampshire to Panama City, Florida flights?

You could potentially save up to 54% on your flight if you consider stops on a Manchester, New Hampshire to Panama City, Florida flight.

When to book flights from Manchester, New Hampshire to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to Panama City, Florida (MHT to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Panama City, Florida

Fastest flight time

6h 50m

Direct flights

None
The fastest flight from Manchester, New Hampshire to Panama City, Florida takes 6h 50m
There are no direct flights from Manchester, New Hampshire to Panama City, Florida. There are no popular flight routes from Manchester, New Hampshire to Panama City, Florida.
Search flight deals

Frequently asked questions about flying from Manchester, New Hampshire to Panama City, Florida

  • How far is Manchester to Panama City NW Florida Beaches by plane?

    Manchester and Panama City NW Florida Beaches are 1182.3 mi apart from one another. Typically, this will take 6h 50m by plane in normal conditions.

  • When did momondo last update prices for flights from Manchester Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Manchester Airport to Panama City NW Florida Beaches Airport are updated daily.

  • How many operators does momondo search for flights from Manchester Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Manchester Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Manchester, New Hampshire to Panama City, Florida?

Best airlines flying from Manchester, New Hampshire to Panama City, Florida

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $262Free CancellationRating
7.1
11,866 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Panama City?

Finding the right flight to Panama City from Manchester is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Manchester to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to Panama City.

I’m not ready to book a flight from Manchester to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Manchester. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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