What is the cheapest airline that flies from Manchester to Des Moines?

American Airlines is the most popular carrier operating from Manchester to Des Moines

What airlines fly to Des Moines?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to Des Moines from Manchester, New Hampshire according to our data. Allegiant Air is the first choice among our users, with 37% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Manchester Airport to Des Moines Airport?

Prices for flights from Manchester Airport to Des Moines Airport refresh daily.

How many operators does momondo search for flights from Manchester Airport to Des Moines Airport?

There is 1 operator available for flights from Manchester Airport to Des Moines Airport as of September 2026.

How old do you have to be to fly from Manchester Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$274 Cheap Flights from Manchester, New Hampshire to Des Moines in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Manchester, New Hampshire to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:15 am - 11:25 amMHT Manchester-DSM Des Moines

5h 10m1 stop Chicago Midway

4:25 pm - 10:00 pmDSM Des Moines-MHT Manchester

4h 35m1 stop Chicago Midway

$364Southwest

Tue, Nov 10 - Fri, Nov 13

2:10 pm - 10:05 pmMHT Manchester-DSM Des Moines

8h 55m2 stops Baltimore/Washington Chicago Midway

4:25 pm - 10:00 pmDSM Des Moines-MHT Manchester

4h 35m1 stop Chicago Midway

$369Southwest

Tue, Nov 10 - Fri, Nov 13

2:10 pm - 10:05 pmMHT Manchester-DSM Des Moines

8h 55m2 stops Baltimore/Washington Chicago Midway

5:25 am - 3:35 pmDSM Des Moines-MHT Manchester

9h 10m2 stops Chicago Midway Nashville Intl

$436Southwest

Tue, Nov 10 - Fri, Nov 13

5:22 pm - 12:19 amMHT Manchester-DSM Des Moines

7h 57m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

7:11 am - 4:51 pmDSM Des Moines-MHT Manchester

8h 40m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

$437American Airlines

Sat, Nov 21 - Tue, Nov 24

6:40 pm - 11:05 pmMHT Manchester-DSM Des Moines

5h 25m1 stop Chicago Midway

5:20 am - 10:50 amDSM Des Moines-MHT Manchester

4h 30m1 stop Chicago Midway

$437Southwest

Sun, Nov 15 - Sat, Nov 21

7:00 pm - 11:00 pmMHT Manchester-DSM Des Moines

5h 00m1 stop Chicago Midway

5:10 am - 2:15 pmDSM Des Moines-MHT Manchester

8h 05m2 stops Chicago Midway Nashville Intl

$442Southwest

Sat, Nov 21 - Tue, Nov 24

7:00 pm - 11:00 pmMHT Manchester-DSM Des Moines

5h 00m1 stop Chicago Midway

5:10 am - 3:55 pmDSM Des Moines-MHT Manchester

9h 45m1 stop Chicago Midway

$442Southwest

Sat, Nov 21 - Tue, Nov 24

6:40 pm - 11:05 pmMHT Manchester-DSM Des Moines

5h 25m1 stop Chicago Midway

5:20 am - 4:40 pmDSM Des Moines-MHT Manchester

10h 20m2 stops Chicago Midway Nashville Intl

$448Southwest

Sun, Nov 15 - Sat, Nov 21

6:55 pm - 11:30 pmMHT Manchester-DSM Des Moines

5h 35m1 stop Chicago Midway

5:10 am - 3:55 pmDSM Des Moines-MHT Manchester

9h 45m1 stop Chicago Midway

$460Southwest

Wed, Dec 23 - Wed, Dec 30

7:09 pm - 11:58 pmMHT Manchester-DSM Des Moines

5h 49m1 stop Charlotte Douglas

5:30 am - 5:13 pmDSM Des Moines-MHT Manchester

10h 43m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

$607American Airlines

Wed, Dec 23 - Thu, Dec 31

Cheap last minute flights

Enter your travel dates to find the best prices.

5:59 pm - 12:04 amMHT Manchester-DSM Des Moines

7h 05m1 stop Chicago O'Hare Intl

5:57 pm - 12:22 amDSM Des Moines-MHT Manchester

5h 25m1 stop Chicago O'Hare Intl

$653American Airlines

Tue, Sep 22 - Sat, Sep 26

12:33 pm - 5:26 pmMHT Manchester-DSM Des Moines

5h 53m1 stop Chicago O'Hare Intl

5:57 pm - 12:22 amDSM Des Moines-MHT Manchester

5h 25m1 stop Chicago O'Hare Intl

$653American Airlines

Tue, Sep 22 - Sat, Sep 26

6:15 pm - 10:00 pmMHT Manchester-DSM Des Moines

4h 45m1 stop Chicago Midway

12:10 pm - 6:20 pmDSM Des Moines-MHT Manchester

5h 10m1 stop Chicago Midway

$653Southwest

Tue, Sep 22 - Sat, Sep 26

3:05 pm - 10:00 pmMHT Manchester-DSM Des Moines

7h 55m2 stops Baltimore/Washington Chicago Midway

5:30 am - 11:15 amDSM Des Moines-MHT Manchester

4h 45m1 stop Chicago Midway

$658Southwest

Tue, Sep 22 - Sat, Sep 26

2:46 pm - 11:33 pmMHT Manchester-DSM Des Moines

9h 47m2 stops Washington, D.C. Dulles Intl Denver Intl

8:00 am - 7:01 pmDSM Des Moines-MHT Manchester

10h 01m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$663United Airlines

Tue, Sep 22 - Sat, Sep 26

9:25 am - 8:26 pmMHT Manchester-DSM Des Moines

12h 01m2 stops Washington, D.C. Dulles Intl Denver Intl

6:00 am - 7:01 pmDSM Des Moines-MHT Manchester

12h 01m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$663United Airlines

Tue, Sep 22 - Sat, Sep 26

1:25 pm - 10:00 pmMHT Manchester-DSM Des Moines

9h 35m2 stops Orlando Chicago Midway

7:20 am - 9:20 pmDSM Des Moines-MHT Manchester

13h 00m2 stops Denver Intl Baltimore/Washington

$663Southwest

Tue, Sep 22 - Sat, Sep 26

9:25 am - 5:35 pmMHT Manchester-DSM Des Moines

9h 10m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

8:00 am - 7:01 pmDSM Des Moines-MHT Manchester

10h 01m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$707United Airlines

Wed, Sep 23 - Sat, Sep 26

5:59 pm - 12:04 amMHT Manchester-DSM Des Moines

7h 05m1 stop Chicago O'Hare Intl

1:09 pm - 9:26 pmDSM Des Moines-MHT Manchester

7h 17m1 stop Philadelphia

$715American Airlines

Wed, Sep 23 - Sat, Sep 26

6:00 am - 5:26 pmMHT Manchester-DSM Des Moines

12h 26m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

1:09 pm - 9:26 pmDSM Des Moines-MHT Manchester

7h 17m1 stop Philadelphia

$731American Airlines

Wed, Sep 23 - Sat, Sep 26

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Southwest flights from Manchester, New Hampshire to Des Moines

Our best Southwest deals on Manchester, New Hampshire to Des Moines flight tickets

Southwest

Nov 10

MHT7:15 amManchester

5h 10m

1 stop

DSM11:25 amDes Moines

Nov 13

DSM4:25 pmDes Moines

4h 35m

1 stop

MHT10:00 pmManchester

$364

Southwest

Nov 10

MHT2:10 pmManchester

8h 55m

2 stops

DSM10:05 pmDes Moines

Nov 13

DSM4:25 pmDes Moines

4h 35m

1 stop

MHT10:00 pmManchester

$369

Southwest

Nov 10

MHT2:10 pmManchester

8h 55m

2 stops

DSM10:05 pmDes Moines

Nov 13

DSM5:25 amDes Moines

9h 10m

2 stops

MHT3:35 pmManchester

$436

United Airlines flights from Manchester, New Hampshire to Des Moines

Our best United Airlines deals on Manchester, New Hampshire to Des Moines flight tickets

United Airlines

Nov 10

MHT2:38 pmManchester

8h 17m

2 stops

DSM9:55 pmDes Moines

Nov 11

DSM1:27 pmDes Moines

9h 32m

2 stops

MHT11:59 pmManchester

$460

United Airlines

Nov 10

MHT2:38 pmManchester

8h 17m

2 stops

DSM9:55 pmDes Moines

Nov 13

DSM11:22 amDes Moines

11h 37m

3 stops

MHT11:59 pmManchester

$657

United Airlines

Nov 21

MHT9:25 amManchester

10h 51m

2 stops

DSM7:16 pmDes Moines

Nov 24

DSM11:22 amDes Moines

11h 37m

3 stops

MHT11:59 pmManchester

$664

momondo Fare Finder

Use the filters below to find and compare flights from Manchester, New Hampshire to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

ManchesterDes Moines

MHT Manchester - DSM Des Moines

MHTDSM

Manchester

Tue 11/10

7:15 am-11:25 am

1 stop5h 10m

Des Moines

Fri 11/13

4:25 pm-10:00 pm

1 stop4h 35m

$364

ManchesterDes Moines

MHT Manchester - DSM Des Moines

MHTDSM

Manchester

Tue 11/10

2:10 pm-10:05 pm

2 stops8h 55m

Des Moines

Fri 11/13

4:25 pm-10:00 pm

1 stop4h 35m

$369

ManchesterDes Moines

MHT Manchester - DSM Des Moines

MHTDSM

Manchester

Tue 11/10

2:10 pm-10:05 pm

2 stops8h 55m

Des Moines

Fri 11/13

5:25 am-3:35 pm

2 stops9h 10m

$436

ManchesterDes Moines

MHT Manchester - DSM Des Moines

MHTDSM

Manchester

Sat 11/21

5:22 pm-12:19 am

2 stops7h 57m

Des Moines

Tue 11/24

7:11 am-4:51 pm

2 stops8h 40m

$437

ManchesterDes Moines

MHT Manchester - DSM Des Moines

MHTDSM

Manchester

Sun 11/15

6:40 pm-11:05 pm

1 stop5h 25m

Des Moines

Sat 11/21

5:20 am-10:50 am

1 stop4h 30m

$437

ManchesterDes Moines

MHT Manchester - DSM Des Moines

MHTDSM

Manchester

Sat 11/21

7:00 pm-11:00 pm

1 stop5h 00m

Des Moines

Tue 11/24

5:10 am-2:15 pm

2 stops8h 05m

$442

ManchesterDes Moines

MHT Manchester - DSM Des Moines

MHTDSM

Manchester

Sat 11/21

7:00 pm-11:00 pm

1 stop5h 00m

Des Moines

Tue 11/24

5:10 am-3:55 pm

1 stop9h 45m

$442

ManchesterDes Moines

MHT Manchester - DSM Des Moines

MHTDSM

Manchester

Sun 11/15

6:40 pm-11:05 pm

1 stop5h 25m

Des Moines

Sat 11/21

5:20 am-4:40 pm

2 stops10h 20m

$448

ManchesterDes Moines

MHT Manchester - DSM Des Moines

MHTDSM

Manchester

Wed 12/23

6:55 pm-11:30 pm

1 stop5h 35m

Des Moines

Wed 12/30

5:10 am-3:55 pm

1 stop9h 45m

$460

ManchesterDes Moines

MHT Manchester - DSM Des Moines

MHTDSM

Manchester

Wed 12/23

7:09 pm-11:58 pm

1 stop5h 49m

Des Moines

Thu 12/31

5:30 am-5:13 pm

2 stops10h 43m

$607

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first

How to get the cheapest flight ticket from Manchester, New Hampshire to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Manchester, New Hampshire to Des Moines is on a Friday. Travelers who choose to depart for Des Moines on a Friday will often find tickets for as low as $124. Flights from Manchester, New Hampshire to Des Moines on a Sunday will generally be more expensive and average around $355. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

Can stopping save me money on Manchester, New Hampshire to Des Moines flights?

You could potentially save up to 24% on your flight if you consider stops on a Manchester, New Hampshire to Des Moines flight.

When to book flights from Manchester, New Hampshire to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Manchester, New Hampshire to Des Moines (MHT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Des Moines

Best Price Found	$274
Fastest flight time	4h 45m
Direct flights	None

The best one-way flight to Des Moines from Manchester, New Hampshire in the past 72 hours is $274. The best round-trip flight deal from Manchester, New Hampshire to Des Moines found on momondo in the last 72 hours is $364.

The fastest flight from Manchester, New Hampshire to Des Moines takes 4h 45m

There are no direct flights from Manchester, New Hampshire to Des Moines. There are no popular flight routes from Manchester, New Hampshire to Des Moines.

Search flight deals

Frequently asked questions about flying from Manchester, New Hampshire to Des Moines

How far is Manchester to Des Moines by plane?
A flight from Manchester to Des Moines will travel around 1133.4 mi. Typically, this will take 4h 45m by plane in normal conditions.
When did momondo last update prices for flights from Manchester Airport to Des Moines Airport?
Prices for flights from Manchester Airport to Des Moines Airport refresh daily.
How many operators does momondo search for flights from Manchester Airport to Des Moines Airport?
There is 1 operator available for flights from Manchester Airport to Des Moines Airport as of September 2026.
How old do you have to be to fly from Manchester Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Manchester, New Hampshire to Des Moines?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Manchester, New Hampshire to Des Moines is American Airlines (100% of total bookings).

Best airlines flying from Manchester, New Hampshire to Des Moines

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $379	Free Cancellation	Rating 7.0 12,072 reviews		Search American Airlines flights

West Des Moines

Ames

Ankeny

Clive

Altoona

Pella

Osceola

Urbandale

Newton

Boone

Johnston

Oskaloosa

Grinnell

Norwalk

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Des Moines?

It is quick and easy to find Manchester to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Manchester to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Manchester on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Manchester to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Manchester. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Manchester to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from Manchester, New Hampshire to Des Moines from $274

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Southwest flights from Manchester, New Hampshire to Des Moines

Our best Southwest deals on Manchester, New Hampshire to Des Moines flight tickets

United Airlines flights from Manchester, New Hampshire to Des Moines

Our best United Airlines deals on Manchester, New Hampshire to Des Moines flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Manchester, New Hampshire to Des Moines that are best for you.

See travel insights to Des Moines from

How to get the cheapest flight ticket from Manchester, New Hampshire to Des Moines

What is the cheapest day to depart on your flight to Des Moines?

Can stopping save me money on Manchester, New Hampshire to Des Moines flights?

What is the cheapest airline that flies from Manchester to Des Moines?

What airlines fly to Des Moines?

When to book flights from Manchester, New Hampshire to Des Moines

Cheap Manchester, New Hampshire to Des Moines (MHT to DSM) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Manchester, New Hampshire to Des Moines

Best airlines flying from Manchester, New Hampshire to Des Moines

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Des Moines with momondo

Traveling to a place near Des Moines?

Why use momondo?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa

Fly your favorite airline to Des Moines

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Des Moines

List of cabin classes available on flights landing in Des Moines. Availability may vary depending on flight origin and airline.

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