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Cheap flights from Manchester, New Hampshire to Des Moines from $148

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Des Moines departing on 9/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Manchester, New Hampshire to Des Moines

Cheap round-trip flights

American Airlines Logo
5:48 pm - 11:28 pmMHT-DSM
6h 40m1 stop
American Airlines Logo
5:00 am - 12:08 pmDSM-MHT
6h 08m1 stop
$295American Airlines
Find Deal
Thu, Sep 18 - Mon, Sep 22
Southwest Logo
12:45 pm - 10:50 pmMHT-DSM
11h 05m2 stops
Southwest Logo
5:30 pm - 8:10 amDSM-MHT
13h 40m2 stops
$311Southwest
Find Deal
Thu, Sep 18 - Mon, Sep 22
American Airlines Logo
5:26 pm - 11:45 pmMHT-DSM
7h 19m1 stop
American Airlines Logo
6:00 am - 11:43 amDSM-MHT
4h 43m1 stop
$327American Airlines
Find Deal
Fri, Sep 5 - Sun, Sep 7
American Airlines Logo
5:20 pm - 10:09 pmMHT-DSM
5h 49m1 stop
American Airlines Logo
3:18 pm - 11:48 pmDSM-MHT
7h 30m1 stop
$357American Airlines
Find Deal
Fri, Nov 7 - Mon, Nov 10
Southwest Logo
2:50 pm - 10:50 pmMHT-DSM
9h 00m2 stops
Southwest Logo
5:30 pm - 8:10 amDSM-MHT
13h 40m2 stops
$387Southwest
Find Deal
Thu, Sep 18 - Mon, Sep 22
Southwest Logo
2:50 pm - 10:50 pmMHT-DSM
9h 00m2 stops
Southwest Logo
5:30 pm - 8:10 amDSM-MHT
13h 40m2 stops
$397Southwest
Find Deal
Thu, Sep 18 - Mon, Sep 22
Southwest Logo
1:40 pm - 11:30 pmMHT-DSM
10h 50m2 stops
Southwest Logo
7:25 am - 9:55 pmDSM-MHT
13h 30m2 stops
$473Southwest
Find Deal
Thu, Oct 16 - Sat, Oct 18
United Airlines Logo
1:30 pm - 9:45 pmMHT-DSM
9h 15m2 stops
United Airlines Logo
6:25 pm - 2:57 pmDSM-MHT
19h 32m2 stops
$476United Airlines
Find Deal
Fri, Sep 5 - Sun, Sep 7
United Airlines Logo
2:27 pm - 12:14 pmMHT-DSM
22h 47m2 stops
United Airlines Logo
6:50 pm - 11:44 pmDSM-MHT
27h 54m2 stops
$548United Airlines
Find Deal
Fri, Nov 7 - Mon, Nov 10
United Airlines Logo
1:30 pm - 9:45 pmMHT-DSM
9h 15m2 stops
United Airlines Logo
6:25 pm - 10:42 amDSM-MHT
15h 17m2 stops
$568United Airlines
Find Deal
Fri, Sep 5 - Fri, Sep 12

United Airlines flights from Manchester, New Hampshire to Des Moines

Our best United Airlines deals on Manchester, New Hampshire to Des Moines flight tickets
United Airlines
Sep 5
MHT1:30 pmManchester
9h 15m
2 stops
DSM9:45 pmDes Moines
Sep 7
DSM6:25 pmDes Moines
19h 32m
2 stops
MHT2:57 pmManchester
$476
Find similar
United Airlines
Nov 7
MHT2:27 pmManchester
22h 47m
2 stops
DSM12:14 pmDes Moines
Nov 10
DSM6:50 pmDes Moines
27h 54m
2 stops
MHT11:44 pmManchester
$548
Find similar
United Airlines
Sep 5
MHT1:30 pmManchester
9h 15m
2 stops
DSM9:45 pmDes Moines
Sep 12
DSM6:25 pmDes Moines
15h 17m
2 stops
MHT10:42 amManchester
$568
Find similar

American Airlines flights from Manchester, New Hampshire to Des Moines

Our best American Airlines deals on Manchester, New Hampshire to Des Moines flight tickets
American Airlines
Sep 18
MHT5:48 pmManchester
6h 40m
1 stop
DSM11:28 pmDes Moines
Sep 22
DSM5:00 amDes Moines
6h 08m
1 stop
MHT12:08 pmManchester
$295
Find similar
American Airlines
Sep 5
MHT5:26 pmManchester
7h 19m
1 stop
DSM11:45 pmDes Moines
Sep 7
DSM6:00 amDes Moines
4h 43m
1 stop
MHT11:43 amManchester
$327
Find similar
American Airlines
Nov 7
MHT5:20 pmManchester
5h 49m
1 stop
DSM10:09 pmDes Moines
Nov 10
DSM3:18 pmDes Moines
7h 30m
1 stop
MHT11:48 pmManchester
$357
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 9/18

5:48 pm-11:28 pm

1 stop6h 40m

Des Moines

Mon 9/22

5:00 am-12:08 pm

1 stop6h 08m

$295

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 9/18

12:45 pm-10:50 pm

2 stops11h 05m

Des Moines

Mon 9/22

5:30 pm-8:10 am

2 stops13h 40m

$311

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 9/5

5:26 pm-11:45 pm

1 stop7h 19m

Des Moines

Sun 9/7

6:00 am-11:43 am

1 stop4h 43m

$327

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 11/7

5:20 pm-10:09 pm

1 stop5h 49m

Des Moines

Mon 11/10

3:18 pm-11:48 pm

1 stop7h 30m

$357

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 9/18

2:50 pm-10:50 pm

2 stops9h 00m

Des Moines

Mon 9/22

5:30 pm-8:10 am

2 stops13h 40m

$387

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 9/18

2:50 pm-10:50 pm

2 stops9h 00m

Des Moines

Mon 9/22

5:30 pm-8:10 am

2 stops13h 40m

$397

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 10/16

1:40 pm-11:30 pm

2 stops10h 50m

Des Moines

Sat 10/18

7:25 am-9:55 pm

2 stops13h 30m

$473

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 9/5

1:30 pm-9:45 pm

2 stops9h 15m

Des Moines

Sun 9/7

6:25 pm-2:57 pm

2 stops19h 32m

$476

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 11/7

2:27 pm-12:14 pm

2 stops22h 47m

Des Moines

Mon 11/10

6:50 pm-11:44 pm

2 stops27h 54m

$548

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 9/5

1:30 pm-9:45 pm

2 stops9h 15m

Des Moines

Fri 9/12

6:25 pm-10:42 am

2 stops15h 17m

$568

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Manchester, New Hampshire to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in May, then August is your next best option. Flight prices from Manchester, New Hampshire to Des Moines during August average around $391.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Manchester, New Hampshire to Des Moines is on a Friday. Travelers who choose to depart for Des Moines on a Friday will often find tickets for as low as $161. Flights from Manchester, New Hampshire to Des Moines on a Monday will generally be more expensive and average around $234. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Manchester, New Hampshire to Des Moines in the morning for as low as $178. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $466. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Manchester, New Hampshire to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to Des Moines (MHT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Des Moines

Best Price Found

$148

Fastest flight time

4h 53m

Direct flights

None

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from Manchester, New Hampshire in the past 72 hours is $148. The best round-trip flight deal from Manchester, New Hampshire to Des Moines found on momondo in the last 72 hours is $295.
The fastest flight from Manchester, New Hampshire to Des Moines takes 4h 53m
There are no direct flights from Manchester, New Hampshire to Des Moines. Popular non-direct route for this connection is Manchester Airport - Des Moines Airport.
There is 1 airport near Des Moines: Des Moines (DSM)
Search flight deals

  • How far is Manchester to Des Moines by plane?

    A flight from Manchester to Des Moines will travel around 1133.4 mi. Typically, this will take 4h 53m by plane in normal conditions.

  • When did momondo last update prices for flights from Manchester Airport to Des Moines Airport?

    Prices for flights from Manchester Airport to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from Manchester Airport to Des Moines Airport?

  • How old do you have to be to fly from Manchester Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Manchester, New Hampshire to Des Moines?

Best airlines flying from Manchester, New Hampshire to Des Moines

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $316Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Newton
Johnston
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Des Moines?

It is quick and easy to find Manchester to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Manchester to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Manchester on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Manchester to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Manchester. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Manchester to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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