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Cheap flights from Manchester, New Hampshire to Des Moines from $244

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Des Moines departing on 4/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Manchester, New Hampshire to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 12:26 pm
MHT
-
DSM
7h 26m1 stop
American Airlines Logo
4:25 pm - 11:46 pm
DSM
-
MHT
6h 21m1 stop
$258American Airlines
mié., dic. 31 - mié., ene. 7
United Airlines Logo
2:33 pm - 11:43 pm
MHT
-
DSM
10h 10m2 stops
United Airlines Logo
8:00 am - 6:53 pm
DSM
-
MHT
9h 53m2 stops
$373United Airlines
sáb., feb. 14 - mié., feb. 18
American Airlines Logo
6:00 am - 12:26 pm
MHT
-
DSM
7h 26m1 stop
American Airlines Logo
11:42 am - 11:46 pm
DSM
-
MHT
11h 04m2 stops
$399American Airlines
mié., dic. 31 - mié., ene. 7
Southwest Logo
7:10 pm - 11:05 pm
MHT
-
DSM
4h 55m1 stop
Southwest Logo
5:20 am - 10:40 am
DSM
-
MHT
4h 20m1 stop
$467Southwest
jue., abr. 16 - dom., abr. 19
Southwest Logo
12:10 pm - 9:55 pm
MHT
-
DSM
10h 45m2 stops
Southwest Logo
5:20 am - 10:40 am
DSM
-
MHT
4h 20m1 stop
$472Southwest
jue., abr. 16 - dom., abr. 19
United Airlines Logo
7:26 pm - 6:05 pm
MHT
-
DSM
23h 39m2 stops
United Airlines Logo
8:00 am - 6:51 pm
DSM
-
MHT
9h 51m2 stops
$474United Airlines
mié., dic. 31 - mié., ene. 7
Southwest Logo
7:10 pm - 11:05 pm
MHT
-
DSM
4h 55m1 stop
Southwest Logo
5:20 am - 10:40 am
DSM
-
MHT
4h 20m1 stop
$477Southwest
vie., may. 15 - dom., may. 17
Southwest Logo
12:10 pm - 9:55 pm
MHT
-
DSM
10h 45m2 stops
Southwest Logo
5:20 am - 5:00 pm
DSM
-
MHT
10h 40m2 stops
$487Southwest
jue., abr. 16 - dom., abr. 19
Southwest Logo
1:10 pm - 11:05 pm
MHT
-
DSM
10h 55m2 stops
Southwest Logo
5:20 am - 10:40 am
DSM
-
MHT
4h 20m1 stop
$502Southwest
vie., may. 15 - dom., may. 17
Southwest Logo
1:10 pm - 11:05 pm
MHT
-
DSM
10h 55m2 stops
Southwest Logo
5:20 am - 5:00 pm
DSM
-
MHT
10h 40m2 stops
$587Southwest
vie., may. 15 - dom., may. 17

United Airlines flights from Manchester, New Hampshire to Des Moines

Our best United Airlines deals on Manchester, New Hampshire to Des Moines flight tickets
United Airlines
Feb 14
MHT2:33 pmManchester
10h 10m
2 stops
DSM11:43 pmDes Moines
Feb 18
DSM8:00 amDes Moines
9h 53m
2 stops
MHT6:53 pmManchester
$373
Find similar
United Airlines
Dec 31
MHT7:26 pmManchester
23h 39m
2 stops
DSM6:05 pmDes Moines
Jan 7
DSM8:00 amDes Moines
9h 51m
2 stops
MHT6:51 pmManchester
$474
Find similar
United Airlines
Dec 13
MHT2:32 pmManchester
8h 05m
2 stops
DSM9:37 pmDes Moines
Jan 28
DSM8:00 amDes Moines
9h 51m
2 stops
MHT6:51 pmManchester
$563
Find similar

Southwest flights from Manchester, New Hampshire to Des Moines

Our best Southwest deals on Manchester, New Hampshire to Des Moines flight tickets
Southwest
Apr 16
MHT7:10 pmManchester
4h 55m
1 stop
DSM11:05 pmDes Moines
Apr 19
DSM5:20 amDes Moines
4h 20m
1 stop
MHT10:40 amManchester
$467
Find similar
Southwest
Apr 16
MHT12:10 pmManchester
10h 45m
2 stops
DSM9:55 pmDes Moines
Apr 19
DSM5:20 amDes Moines
4h 20m
1 stop
MHT10:40 amManchester
$472
Find similar
Southwest
May 15
MHT7:10 pmManchester
4h 55m
1 stop
DSM11:05 pmDes Moines
May 17
DSM5:20 amDes Moines
4h 20m
1 stop
MHT10:40 amManchester
$477
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 4, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

mié. 12/31

6:00 am-12:26 pm

1 stop7h 26m

Des Moines

mié. 1/7

4:25 pm-11:46 pm

1 stop6h 21m

$258

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

sáb. 2/14

2:33 pm-11:43 pm

2 stops10h 10m

Des Moines

mié. 2/18

8:00 am-6:53 pm

2 stops9h 53m

$373

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

mié. 12/31

6:00 am-12:26 pm

1 stop7h 26m

Des Moines

mié. 1/7

11:42 am-11:46 pm

2 stops11h 04m

$399

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

jue. 4/16

7:10 pm-11:05 pm

1 stop4h 55m

Des Moines

dom. 4/19

5:20 am-10:40 am

1 stop4h 20m

$467

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

jue. 4/16

12:10 pm-9:55 pm

2 stops10h 45m

Des Moines

dom. 4/19

5:20 am-10:40 am

1 stop4h 20m

$472

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

mié. 12/31

7:26 pm-6:05 pm

2 stops23h 39m

Des Moines

mié. 1/7

8:00 am-6:51 pm

2 stops9h 51m

$474

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

vie. 5/15

7:10 pm-11:05 pm

1 stop4h 55m

Des Moines

dom. 5/17

5:20 am-10:40 am

1 stop4h 20m

$477

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

jue. 4/16

12:10 pm-9:55 pm

2 stops10h 45m

Des Moines

dom. 4/19

5:20 am-5:00 pm

2 stops10h 40m

$487

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

vie. 5/15

1:10 pm-11:05 pm

2 stops10h 55m

Des Moines

dom. 5/17

5:20 am-10:40 am

1 stop4h 20m

$502

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

vie. 5/15

1:10 pm-11:05 pm

2 stops10h 55m

Des Moines

dom. 5/17

5:20 am-5:00 pm

2 stops10h 40m

$587

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Manchester, New Hampshire to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Manchester, New Hampshire to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $132. Flights from Manchester, New Hampshire to Des Moines on a Wednesday will generally be more expensive and average around $309. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Manchester, New Hampshire to Des Moines in the morning for as low as $161. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $466. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Manchester, New Hampshire to Des Moines flights?

You could potentially save up to 53% on your flight if you consider stops on a Manchester, New Hampshire to Des Moines flight.

When to book flights from Manchester, New Hampshire to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to Des Moines (MHT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Des Moines

Fastest flight time

4h 55m

Direct flights

None
The fastest flight from Manchester, New Hampshire to Des Moines takes 4h 55m
There are no direct flights from Manchester, New Hampshire to Des Moines. There are no popular flight routes from Manchester, New Hampshire to Des Moines.
Search flight deals

  • How far is Manchester to Des Moines by plane?

    A flight from Manchester to Des Moines will travel around 1133.4 mi. Typically, this will take 4h 55m by plane in normal conditions.

  • When did momondo last update prices for flights from Manchester Airport to Des Moines Airport?

    Prices for flights from Manchester Airport to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from Manchester Airport to Des Moines Airport?

  • How old do you have to be to fly from Manchester Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Manchester, New Hampshire to Des Moines?

Best airlines flying from Manchester, New Hampshire to Des Moines

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $316Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Boone
Osceola
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Des Moines?

It is quick and easy to find Manchester to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Manchester to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Manchester on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Manchester to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Manchester. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Manchester to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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