Cheap flights from Las Vegas to St. Louis from $65

In general, October is the cheapest month to fly from Las Vegas to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $164. The month of December is another great option to travel to St. Louis, with average flight prices from Las Vegas averaging around $203.

The cheapest day to depart on your flight to St. Louis is on a Friday when prices can be found for as low as $239. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $418. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

Flying to St. Louis from Las Vegas in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $198 when looking at flights departing in the afternoon. In the morning is when there is more demand to fly to St. Louis, so prices are often more expensive at around $311 per ticket.

Fly from Las Vegas Harry Reid Intl to Lambert-St Louis for the best Las Vegas Harry Reid Intl - Lambert-St Louis flight prices

You are more likely to see cheaper flights to St. Louis from Las Vegas when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $254 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Las Vegas for as low as $200 on momondo.

There is only 1 cabin class available to choose from on Las Vegas to St. Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 42% on your flight if you consider stops on a Las Vegas to St. Louis flight.

As of May 2026, prices for Las Vegas to St. Louis flights are approximately 132% more expensive when compared to flights at the same time last year.

Frontier is the most popular carrier operating from Las Vegas Harry Reid Intl to Lambert-St Louis

Frontier, Southwest and United Airlines are the top three most popular airlines that fly to St. Louis from Las Vegas according to our data. Frontier is the first choice among our users, with 80% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 5 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

Salt Lake City (SLC) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Denver (DEN) offer the lowest average round-trip price of $142.

Flights connecting via Salt Lake City (SLC) have the shortest average one-way travel time: 5h 01m.

Salt Lake City (SLC) has the shortest average layover time for this route: 0h 57m.

4 flights are operational daily from Las Vegas to St. Louis as of May 2026. The most popular departure time for this route is 2:00PM, with 53% of flights per day taking off in the afternoon.

33 flights are operational weekly from Las Vegas to St. Louis as of May 2026. The most popular departure day for this route is Mon, with 30% of flights per week taking off on this day.