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Cheap flights from Knoxville to Panama City from $143

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:07 pm - 11:48 pmTYS  Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches
6h 41m1 stop Charlotte Douglas
American Airlines Logo
12:00 pm - 6:44 pmECP  Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson
5h 44m1 stop Charlotte Douglas
$259American Airlines
Fri, Dec 4 - Mon, Dec 7
American Airlines Logo
8:10 am - 11:36 amTYS  Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches
4h 26m1 stop Charlotte Douglas
American Airlines Logo
5:50 pm - 10:53 pmECP  Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson
4h 03m1 stop Charlotte Douglas
$259American Airlines
Wed, Jan 27 - Sat, Jan 30
Delta Logo
5:40 am - 8:38 amTYS  Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches
3h 58m1 stop Atlanta Hartsfield-Jackson
Delta Logo
1:37 pm - 6:33 pmECP  Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson
3h 56m1 stop Atlanta Hartsfield-Jackson
$259Delta
Wed, Dec 2 - Mon, Dec 7
Delta Logo
7:07 am - 11:04 amTYS  Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches
4h 57m1 stop Atlanta Hartsfield-Jackson
Delta Logo
9:23 am - 3:05 pmECP  Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson
4h 42m1 stop Atlanta Hartsfield-Jackson
$275Delta
Wed, Jan 13 - Sat, Jan 16
Delta Logo
5:57 pm - 10:47 pmTYS  Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches
5h 50m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 11:06 amECP  Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson
4h 06m1 stop Atlanta Hartsfield-Jackson
$275Delta
Wed, Jan 20 - Sat, Jan 23
Southwest Logo
7:05 am - 9:30 amTYS  Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches
3h 25m1 stop Nashville Intl
Southwest Logo
7:55 am - 12:10 pmECP  Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson
3h 15m1 stop Nashville Intl
$292Southwest
Tue, Nov 10 - Sun, Nov 15
American Airlines Logo
12:30 pm - 5:20 pmTYS  Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches
5h 50m1 stop Charlotte Douglas
American Airlines Logo
5:50 pm - 10:53 pmECP  Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson
4h 03m1 stop Charlotte Douglas
$294American Airlines
Thu, Jan 21 - Sun, Jan 24
Southwest Logo
7:00 am - 3:15 pmTYS  Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches
9h 15m2 stops Nashville Intl Dallas Love Field
Southwest Logo
7:35 am - 12:00 pmECP  Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson
3h 25m1 stop Nashville Intl
$298Southwest
Wed, Jan 13 - Sat, Jan 16
United Airlines Logo
12:20 pm - 1:17 pmTYS  Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches
25h 57m2 stops Newark Chicago O'Hare Intl
United Airlines Logo
2:08 pm - 11:45 amECP  Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson
20h 37m3 stops Chicago O'Hare Intl Washington, D.C. Reagan-National Newark
$840United Airlines
Fri, Jan 15 - Mon, Jan 18
United Airlines Logo
12:00 pm - 9:43 pmTYS  Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches
10h 43m1 stop Houston George Bush Intcntl
United Airlines Logo
8:50 am - 2:36 pmECP  Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson
28h 46m2 stops Houston George Bush Intcntl Denver Intl
$868United Airlines
Tue, Feb 2 - Wed, Feb 3

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Delta flights from Knoxville to Panama City, Florida

Our best Delta deals on Knoxville to Panama City, Florida flight tickets
Delta
Dec 2
TYS5:40 amKnoxville McGhee Tyson
3h 58m
1 stop
ECP8:38 amPanama City NW Florida Beaches
Dec 7
ECP1:37 pmPanama City NW Florida Beaches
3h 56m
1 stop
TYS6:33 pmKnoxville McGhee Tyson
$259
Delta
Jan 13
TYS7:07 amKnoxville McGhee Tyson
4h 57m
1 stop
ECP11:04 amPanama City NW Florida Beaches
Jan 16
ECP9:23 amPanama City NW Florida Beaches
4h 42m
1 stop
TYS3:05 pmKnoxville McGhee Tyson
$275
Delta
Oct 27
TYS5:40 amKnoxville McGhee Tyson
3h 34m
1 stop
ECP8:14 amPanama City NW Florida Beaches
Oct 31
ECP7:12 amPanama City NW Florida Beaches
5h 19m
1 stop
TYS1:31 pmKnoxville McGhee Tyson
$285

Southwest flights from Knoxville to Panama City, Florida

Our best Southwest deals on Knoxville to Panama City, Florida flight tickets
Southwest
Nov 10
TYS7:05 amKnoxville McGhee Tyson
3h 25m
1 stop
ECP9:30 amPanama City NW Florida Beaches
Nov 15
ECP7:55 amPanama City NW Florida Beaches
3h 15m
1 stop
TYS12:10 pmKnoxville McGhee Tyson
$292
Southwest
Nov 10
TYS7:05 amKnoxville McGhee Tyson
9h 30m
2 stops
ECP3:35 pmPanama City NW Florida Beaches
Nov 15
ECP7:55 amPanama City NW Florida Beaches
3h 15m
1 stop
TYS12:10 pmKnoxville McGhee Tyson
$298
Southwest
Nov 10
TYS7:05 amKnoxville McGhee Tyson
9h 30m
2 stops
ECP3:35 pmPanama City NW Florida Beaches
Nov 15
ECP7:55 amPanama City NW Florida Beaches
3h 15m
1 stop
TYS12:10 pmKnoxville McGhee Tyson
$308

momondo Fare Finder

 
Use the filters below to find and compare flights from Knoxville to Panama City, Florida that are best for you.

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Cheapest round-trip

KnoxvillePanama City

TYS Knoxville McGhee Tyson - ECP Panama City NW Florida Beaches

TYSECP

Knoxville McGhee Tyson

Fri 12/4

6:07 pm-11:48 pm

1 stop6h 41m

Panama City NW Florida Beaches

Mon 12/7

12:00 pm-6:44 pm

1 stop5h 44m

$259

KnoxvillePanama City

TYS Knoxville McGhee Tyson - ECP Panama City NW Florida Beaches

TYSECP

Knoxville McGhee Tyson

Wed 1/27

8:10 am-11:36 am

1 stop4h 26m

Panama City NW Florida Beaches

Sat 1/30

5:50 pm-10:53 pm

1 stop4h 03m

$259

KnoxvillePanama City

TYS Knoxville McGhee Tyson - ECP Panama City NW Florida Beaches

TYSECP

Knoxville McGhee Tyson

Wed 12/2

5:40 am-8:38 am

1 stop3h 58m

Panama City NW Florida Beaches

Mon 12/7

1:37 pm-6:33 pm

1 stop3h 56m

$259

KnoxvillePanama City

TYS Knoxville McGhee Tyson - ECP Panama City NW Florida Beaches

TYSECP

Knoxville McGhee Tyson

Wed 1/13

7:07 am-11:04 am

1 stop4h 57m

Panama City NW Florida Beaches

Sat 1/16

9:23 am-3:05 pm

1 stop4h 42m

$275

KnoxvillePanama City

TYS Knoxville McGhee Tyson - ECP Panama City NW Florida Beaches

TYSECP

Knoxville McGhee Tyson

Wed 1/20

5:57 pm-10:47 pm

1 stop5h 50m

Panama City NW Florida Beaches

Sat 1/23

6:00 am-11:06 am

1 stop4h 06m

$275
Quickest round-trip

KnoxvillePanama City

TYS Knoxville McGhee Tyson - ECP Panama City NW Florida Beaches

TYSECP

Knoxville McGhee Tyson

Tue 11/10

7:05 am-9:30 am

1 stop3h 25m

Panama City NW Florida Beaches

Sun 11/15

7:55 am-12:10 pm

1 stop3h 15m

$292

KnoxvillePanama City

TYS Knoxville McGhee Tyson - ECP Panama City NW Florida Beaches

TYSECP

Knoxville McGhee Tyson

Thu 1/21

12:30 pm-5:20 pm

1 stop5h 50m

Panama City NW Florida Beaches

Sun 1/24

5:50 pm-10:53 pm

1 stop4h 03m

$294

KnoxvillePanama City

TYS Knoxville McGhee Tyson - ECP Panama City NW Florida Beaches

TYSECP

Knoxville McGhee Tyson

Wed 1/13

7:00 am-3:15 pm

2 stops9h 15m

Panama City NW Florida Beaches

Sat 1/16

7:35 am-12:00 pm

1 stop3h 25m

$298

KnoxvillePanama City

TYS Knoxville McGhee Tyson - ECP Panama City NW Florida Beaches

TYSECP

Knoxville McGhee Tyson

Fri 1/15

12:20 pm-1:17 pm

2 stops25h 57m

Panama City NW Florida Beaches

Mon 1/18

2:08 pm-11:45 am

3 stops20h 37m

$840

KnoxvillePanama City

TYS Knoxville McGhee Tyson - ECP Panama City NW Florida Beaches

TYSECP

Knoxville McGhee Tyson

Tue 2/2

12:00 pm-9:43 pm

1 stop10h 43m

Panama City NW Florida Beaches

Wed 2/3

8:50 am-2:36 pm

2 stops28h 46m

$868

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Knoxville to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Panama City, Florida?

Prices are currently low for flights on this route.

Typical prices usually range from $366 to $477.
The lowest price recently found on this route was $240.

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Knoxville is in May. Flight prices, which tend to average around $312, are often lower during this time because this is during the off-season. The month of January is another great option to travel to Panama City, Florida, with average flight prices from Knoxville averaging around $326.

When to book flights from Knoxville to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Panama City, Florida (TYS to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Panama City, Florida

Best Price Found

$143

Fastest flight time

3h 15m

Direct flights

None
The best one-way flight to Panama City, Florida from Knoxville in the past 72 hours is $143. The best round-trip flight deal from Knoxville to Panama City, Florida found on momondo in the last 72 hours is $259.
The fastest flight from Knoxville to Panama City, Florida takes 3h 15m
There are no direct flights from Knoxville to Panama City, Florida. There are no popular flight routes from Knoxville to Panama City, Florida.
Search flight deals

Frequently asked questions about flying from Knoxville to Panama City, Florida

  • How far is Knoxville McGhee Tyson to Panama City NW Florida Beaches by plane?

    The distance between Knoxville McGhee Tyson and Panama City NW Florida Beaches is about 413.0 mi. In terms of flight time, this usually takes a little over 3h 15m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Panama City NW Florida Beaches Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents you'll need for your trip to Panama City NW Florida Beaches Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Panama City, Florida?

Best airlines flying from Knoxville to Panama City, Florida

Compare and see reviews for airlines that fly from Knoxville to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $242Free CancellationRating
8.0
4,192 reviews
Search Southwest flights
DeltaPriceFrom $265Free CancellationRating
7.8
8,591 reviews
Search Delta flights
American AirlinesPriceFrom $326Free CancellationRating
7.0
12,073 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Panama City?

Finding the right flight to Panama City from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Knoxville to Panama City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama City from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Panama City?

momondo helps you find the best flight between Knoxville and Panama City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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