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Cheap flights from Knoxville to Indianapolis from $108

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Indianapolis departing on 9/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Indianapolis

Cheap round-trip flights

Allegiant Air Logo
10:45 am - 7:01 pmTYS-IND
8h 16m1 stop
Allegiant Air Logo
12:59 pm - 8:35 pmIND-TYS
7h 36m1 stop
$206Allegiant Air
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Mon, Sep 29 - Thu, Oct 2
Delta Logo
6:14 pm - 9:45 pmTYS-IND
3h 31m1 stop
Delta Logo
7:15 am - 1:12 pmIND-TYS
5h 57m1 stop
$209Delta
Find Deal
Sat, Aug 30 - Sat, Sep 6
American Airlines Logo
12:42 pm - 9:40 pmTYS-IND
8h 58m2 stops
American Airlines Logo
6:08 am - 9:56 amIND-TYS
3h 48m1 stop
$214American Airlines
Find Deal
Sat, Aug 30 - Sat, Sep 6
Logo
9:54 pm - 11:31 amTYS-IND
13h 37m1 stop
Logo
7:43 pm - 10:33 amIND-TYS
14h 50m1 stop
$215
Find Deal
Fri, Oct 3 - Mon, Oct 6
American Airlines Logo
12:42 pm - 9:40 pmTYS-IND
8h 58m2 stops
American Airlines Logo
3:58 pm - 11:03 pmIND-TYS
7h 05m2 stops
$219American Airlines
Find Deal
Sat, Aug 30 - Sat, Sep 6
American Airlines Logo
7:45 pm - 11:10 pmTYS-IND
3h 25m1 stop
American Airlines Logo
6:56 pm - 11:50 pmIND-TYS
4h 54m1 stop
$229American Airlines
Find Deal
Fri, Oct 3 - Mon, Oct 6
Logo
10:45 am - 7:01 pmTYS-IND
8h 16m1 stop
Logo
5:45 am - 11:08 pmIND-TYS
17h 23m2 stops
$231
Find Deal
Fri, Sep 19 - Sun, Sep 21
Logo
9:54 pm - 5:09 pmTYS-IND
19h 15m2 stops
Logo
7:43 pm - 10:33 amIND-TYS
14h 50m1 stop
$252
Find Deal
Fri, Oct 3 - Mon, Oct 6
United Airlines Logo
5:45 am - 10:35 amTYS-IND
4h 50m1 stop
United Airlines Logo
6:00 am - 10:13 amIND-TYS
4h 13m1 stop
$289United Airlines
Find Deal
Fri, Aug 15 - Tue, Aug 19
United Airlines Logo
5:45 am - 10:28 amTYS-IND
4h 43m1 stop
United Airlines Logo
5:45 am - 10:48 amIND-TYS
5h 03m1 stop
$384United Airlines
Find Deal
Wed, Nov 12 - Fri, Nov 14

American Airlines flights from Knoxville to Indianapolis

Our best American Airlines deals on Knoxville to Indianapolis flight tickets
American Airlines
Aug 30
TYS12:42 pmKnoxville McGhee Tyson
8h 58m
2 stops
IND9:40 pmIndianapolis
Sep 6
IND6:08 amIndianapolis
3h 48m
1 stop
TYS9:56 amKnoxville McGhee Tyson
$214
Find similar
American Airlines
Aug 30
TYS12:42 pmKnoxville McGhee Tyson
8h 58m
2 stops
IND9:40 pmIndianapolis
Sep 6
IND3:58 pmIndianapolis
7h 05m
2 stops
TYS11:03 pmKnoxville McGhee Tyson
$219
Find similar
American Airlines
Oct 3
TYS7:45 pmKnoxville McGhee Tyson
3h 25m
1 stop
IND11:10 pmIndianapolis
Oct 6
IND6:56 pmIndianapolis
4h 54m
1 stop
TYS11:50 pmKnoxville McGhee Tyson
$229
Find similar

United Airlines flights from Knoxville to Indianapolis

Our best United Airlines deals on Knoxville to Indianapolis flight tickets
United Airlines
Aug 15
TYS5:45 amKnoxville McGhee Tyson
4h 50m
1 stop
IND10:35 amIndianapolis
Aug 19
IND6:00 amIndianapolis
4h 13m
1 stop
TYS10:13 amKnoxville McGhee Tyson
$289
Find similar
United Airlines
Nov 12
TYS5:45 amKnoxville McGhee Tyson
4h 43m
1 stop
IND10:28 amIndianapolis
Nov 14
IND5:45 amIndianapolis
5h 03m
1 stop
TYS10:48 amKnoxville McGhee Tyson
$384
Find similar
United Airlines
Aug 29
TYS7:00 amKnoxville McGhee Tyson
6h 17m
1 stop
IND1:17 pmIndianapolis
Sep 5
IND9:05 amIndianapolis
11h 51m
2 stops
TYS8:56 pmKnoxville McGhee Tyson
$398
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 2, 2025.
Use the filters below to find and compare flights from Knoxville to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Mon 9/29

10:45 am-7:01 pm

1 stop8h 16m

Indianapolis

Thu 10/2

12:59 pm-8:35 pm

1 stop7h 36m

$206

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Sat 8/30

6:14 pm-9:45 pm

1 stop3h 31m

Indianapolis

Sat 9/6

7:15 am-1:12 pm

1 stop5h 57m

$209

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Sat 8/30

12:42 pm-9:40 pm

2 stops8h 58m

Indianapolis

Sat 9/6

6:08 am-9:56 am

1 stop3h 48m

$214

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Fri 10/3

9:54 pm-11:31 am

1 stop13h 37m

Indianapolis

Mon 10/6

7:43 pm-10:33 am

1 stop14h 50m

$215

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Sat 8/30

12:42 pm-9:40 pm

2 stops8h 58m

Indianapolis

Sat 9/6

3:58 pm-11:03 pm

2 stops7h 05m

$219

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Fri 10/3

7:45 pm-11:10 pm

1 stop3h 25m

Indianapolis

Mon 10/6

6:56 pm-11:50 pm

1 stop4h 54m

$229

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Fri 9/19

10:45 am-7:01 pm

1 stop8h 16m

Indianapolis

Sun 9/21

5:45 am-11:08 pm

2 stops17h 23m

$231

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Fri 10/3

9:54 pm-5:09 pm

2 stops19h 15m

Indianapolis

Mon 10/6

7:43 pm-10:33 am

1 stop14h 50m

$252

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Fri 8/15

5:45 am-10:35 am

1 stop4h 50m

Indianapolis

Tue 8/19

6:00 am-10:13 am

1 stop4h 13m

$289

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Wed 11/12

5:45 am-10:28 am

1 stop4h 43m

Indianapolis

Fri 11/14

5:45 am-10:48 am

1 stop5h 03m

$384

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Indianapolis from

How to get the cheapest flight ticket from Knoxville to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Indianapolis?

In general, April is the cheapest month to fly from Knoxville to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $233. If you are unable to visit Indianapolis during the month of April, then departing from Knoxville during the month August is also very affordable. Most momondo users find prices during this month for around $238.

What is the cheapest day to depart on your flight to Indianapolis?

Our data shows that Saturday is the least expensive day to fly to Indianapolis. Tickets to fly out on this day can be as low as $238. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Indianapolis on Sunday is $522.

What is the cheapest time of day to depart on your flight to Indianapolis?

Flying to Indianapolis from Knoxville in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $238 when looking at flights departing in the afternoon. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $387 on average. Flights to Indianapolis from Knoxville at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How have Knoxville to Indianapolis flight prices changed over time?

When to book flights from Knoxville to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Indianapolis (TYS to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Indianapolis

Best Price Found

$108

Fastest flight time

3h 25m

Direct flights

None

Airports in Indianapolis

1 airport
The best one-way flight to Indianapolis from Knoxville in the past 72 hours is $108. The best round-trip flight deal from Knoxville to Indianapolis found on momondo in the last 72 hours is $206.
The fastest flight from Knoxville to Indianapolis takes 3h 25m
There are no direct flights from Knoxville to Indianapolis. Popular non-direct route for this connection is Knoxville McGhee Tyson Airport - Indianapolis Airport.
There is 1 airport near Indianapolis: Indianapolis (IND)
Search flight deals

  • How far is Knoxville McGhee Tyson to Indianapolis by plane?

    Knoxville McGhee Tyson and Indianapolis are 289.8 mi apart from one another. By plane, this route typically takes 3h 25m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Indianapolis Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Indianapolis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Indianapolis Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Indianapolis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The travel and health documents you'll need for your trip to Indianapolis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Indianapolis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Indianapolis?

Best airlines flying from Knoxville to Indianapolis

Compare and see reviews for airlines that fly from Knoxville to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $208Free CancellationRating
8.0
7,985 reviews
Search Delta flights
American AirlinesPriceFrom $218Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $223Free CancellationRating
7.4
8,905 reviews
Search United Airlines flights

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Anderson
Muncie
Plainfield
Greenwood
Noblesville
Fishers
Carmel
Shelbyville
West Lafayette
Seymour
Franklin
Brownsburg
Crawfordsville
Greenfield
Speedway
Westfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Indianapolis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Indianapolis for you.

Can I find flights from Knoxville to Indianapolis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Indianapolis flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Indianapolis?

momondo provides multiple filters to help you find the best flight to Indianapolis from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Indianapolis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Indianapolis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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