Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Knoxville to Indianapolis from $114

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Indianapolis departing on 11/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Indianapolis

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:06 pm - 11:41 pmTYS  Knoxville McGhee Tyson-IND Indianapolis
5h 35m1 stop Charlotte Douglas
American Airlines Logo
6:00 am - 9:44 amIND  Indianapolis-TYS Knoxville McGhee Tyson
3h 44m1 stop Charlotte Douglas
$227American Airlines
Thu, Sep 10 - Wed, Sep 16
American Airlines Logo
8:00 am - 2:01 pmTYS  Knoxville McGhee Tyson-IND Indianapolis
6h 01m1 stop Chicago O'Hare Intl
American Airlines Logo
6:00 am - 10:38 amIND  Indianapolis-TYS Knoxville McGhee Tyson
4h 38m1 stop Washington, D.C. Reagan-National
$228American Airlines
Wed, Sep 9 - Wed, Sep 16
American Airlines Logo
7:06 am - 12:04 pmTYS  Knoxville McGhee Tyson-IND Indianapolis
4h 58m1 stop Washington, D.C. Reagan-National
American Airlines Logo
6:00 am - 10:45 amIND  Indianapolis-TYS Knoxville McGhee Tyson
4h 45m1 stop Washington, D.C. Reagan-National
$229American Airlines
Tue, Sep 1 - Wed, Sep 2
Southwest Logo
7:10 am - 2:50 pmTYS  Knoxville McGhee Tyson-IND Indianapolis
7h 40m2 stops Nashville Intl Atlanta Hartsfield-Jackson
Southwest Logo
6:40 am - 1:05 pmIND  Indianapolis-TYS Knoxville McGhee Tyson
6h 25m1 stop Orlando
$245Southwest
Thu, Sep 10 - Wed, Sep 16
Southwest Logo
7:00 am - 4:55 pmTYS  Knoxville McGhee Tyson-IND Indianapolis
9h 55m2 stops Nashville Intl Baltimore/Washington
Southwest Logo
6:40 am - 1:05 pmIND  Indianapolis-TYS Knoxville McGhee Tyson
6h 25m1 stop Orlando
$246Southwest
Wed, Sep 9 - Wed, Sep 16
Southwest Logo
7:00 am - 4:55 pmTYS  Knoxville McGhee Tyson-IND Indianapolis
9h 55m2 stops Nashville Intl Baltimore/Washington
Southwest Logo
6:50 am - 12:05 pmIND  Indianapolis-TYS Knoxville McGhee Tyson
5h 15m1 stop Nashville Intl
$256Southwest
Tue, Sep 1 - Wed, Sep 2
Delta Logo
6:25 pm - 12:32 amTYS  Knoxville McGhee Tyson-IND Indianapolis
6h 07m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:59 pm - 11:55 pmIND  Indianapolis-TYS Knoxville McGhee Tyson
3h 56m1 stop Atlanta Hartsfield-Jackson
$257Delta
Fri, Sep 25 - Mon, Sep 28
Delta Logo
6:25 pm - 11:22 pmTYS  Knoxville McGhee Tyson-IND Indianapolis
4h 57m1 stop Atlanta Hartsfield-Jackson
Delta Logo
4:43 pm - 8:15 pmIND  Indianapolis-TYS Knoxville McGhee Tyson
3h 32m1 stop Atlanta Hartsfield-Jackson
$257Delta
Fri, Sep 25 - Mon, Sep 28
Delta Logo
6:25 pm - 11:22 pmTYS  Knoxville McGhee Tyson-IND Indianapolis
4h 57m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:38 pm - 11:55 pmIND  Indianapolis-TYS Knoxville McGhee Tyson
5h 17m1 stop Atlanta Hartsfield-Jackson
$257Delta
Fri, Sep 25 - Mon, Sep 28
American Airlines Logo
7:50 am - 12:13 pmTYS  Knoxville McGhee Tyson-IND Indianapolis
4h 23m1 stop Chicago O'Hare Intl
American Airlines Logo
10:17 am - 4:07 pmIND  Indianapolis-TYS Knoxville McGhee Tyson
5h 50m1 stop Charlotte Douglas
$287American Airlines
Thu, Nov 5 - Sun, Nov 8

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

United Airlines flights from Knoxville to Indianapolis

Our best United Airlines deals on Knoxville to Indianapolis flight tickets
United Airlines
Oct 29
TYS1:51 pmKnoxville McGhee Tyson
4h 55m
1 stop
IND6:46 pmIndianapolis
Nov 2
IND4:30 pmIndianapolis
4h 24m
1 stop
TYS8:54 pmKnoxville McGhee Tyson
$297
United Airlines
Sep 11
TYS7:20 pmKnoxville McGhee Tyson
4h 36m
1 stop
IND11:56 pmIndianapolis
Sep 18
IND4:25 pmIndianapolis
6h 24m
1 stop
TYS10:49 pmKnoxville McGhee Tyson
$310
United Airlines
Oct 29
TYS9:45 amKnoxville McGhee Tyson
11h 01m
2 stops
IND8:46 pmIndianapolis
Nov 2
IND4:30 pmIndianapolis
4h 24m
1 stop
TYS8:54 pmKnoxville McGhee Tyson
$386

Southwest flights from Knoxville to Indianapolis

Our best Southwest deals on Knoxville to Indianapolis flight tickets
Southwest
Sep 10
TYS7:10 amKnoxville McGhee Tyson
7h 40m
2 stops
IND2:50 pmIndianapolis
Sep 16
IND6:40 amIndianapolis
6h 25m
1 stop
TYS1:05 pmKnoxville McGhee Tyson
$245
Southwest
Sep 9
TYS7:00 amKnoxville McGhee Tyson
9h 55m
2 stops
IND4:55 pmIndianapolis
Sep 16
IND6:40 amIndianapolis
6h 25m
1 stop
TYS1:05 pmKnoxville McGhee Tyson
$246
Southwest
Sep 1
TYS7:00 amKnoxville McGhee Tyson
9h 55m
2 stops
IND4:55 pmIndianapolis
Sep 2
IND6:50 amIndianapolis
5h 15m
1 stop
TYS12:05 pmKnoxville McGhee Tyson
$256

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from Knoxville to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleIndianapolis

TYS Knoxville McGhee Tyson - IND Indianapolis

TYSIND

Knoxville McGhee Tyson

Thu 9/10

6:06 pm-11:41 pm

1 stop5h 35m

Indianapolis

Wed 9/16

6:00 am-9:44 am

1 stop3h 44m

$227

KnoxvilleIndianapolis

TYS Knoxville McGhee Tyson - IND Indianapolis

TYSIND

Knoxville McGhee Tyson

Wed 9/9

8:00 am-2:01 pm

1 stop6h 01m

Indianapolis

Wed 9/16

6:00 am-10:38 am

1 stop4h 38m

$228

KnoxvilleIndianapolis

TYS Knoxville McGhee Tyson - IND Indianapolis

TYSIND

Knoxville McGhee Tyson

Tue 9/1

7:06 am-12:04 pm

1 stop4h 58m

Indianapolis

Wed 9/2

6:00 am-10:45 am

1 stop4h 45m

$229

KnoxvilleIndianapolis

TYS Knoxville McGhee Tyson - IND Indianapolis

TYSIND

Knoxville McGhee Tyson

Thu 9/10

7:10 am-2:50 pm

2 stops7h 40m

Indianapolis

Wed 9/16

6:40 am-1:05 pm

1 stop6h 25m

$245

KnoxvilleIndianapolis

TYS Knoxville McGhee Tyson - IND Indianapolis

TYSIND

Knoxville McGhee Tyson

Wed 9/9

7:00 am-4:55 pm

2 stops9h 55m

Indianapolis

Wed 9/16

6:40 am-1:05 pm

1 stop6h 25m

$246

KnoxvilleIndianapolis

TYS Knoxville McGhee Tyson - IND Indianapolis

TYSIND

Knoxville McGhee Tyson

Tue 9/1

7:00 am-4:55 pm

2 stops9h 55m

Indianapolis

Wed 9/2

6:50 am-12:05 pm

1 stop5h 15m

$256

KnoxvilleIndianapolis

TYS Knoxville McGhee Tyson - IND Indianapolis

TYSIND

Knoxville McGhee Tyson

Fri 9/25

6:25 pm-12:32 am

1 stop6h 07m

Indianapolis

Mon 9/28

7:59 pm-11:55 pm

1 stop3h 56m

$257
Quickest round-trip

KnoxvilleIndianapolis

TYS Knoxville McGhee Tyson - IND Indianapolis

TYSIND

Knoxville McGhee Tyson

Fri 9/25

6:25 pm-11:22 pm

1 stop4h 57m

Indianapolis

Mon 9/28

4:43 pm-8:15 pm

1 stop3h 32m

$257

KnoxvilleIndianapolis

TYS Knoxville McGhee Tyson - IND Indianapolis

TYSIND

Knoxville McGhee Tyson

Fri 9/25

6:25 pm-11:22 pm

1 stop4h 57m

Indianapolis

Mon 9/28

6:38 pm-11:55 pm

1 stop5h 17m

$257

KnoxvilleIndianapolis

TYS Knoxville McGhee Tyson - IND Indianapolis

TYSIND

Knoxville McGhee Tyson

Thu 11/5

7:50 am-12:13 pm

1 stop4h 23m

Indianapolis

Sun 11/8

10:17 am-4:07 pm

1 stop5h 50m

$287

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Indianapolis from

How to get the cheapest flight ticket from Knoxville to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Indianapolis?

Prices are currently low for flights on this route.

Typical prices usually range from $233 to $248.
The lowest price recently found on this route was $223.

What is the cheapest month to fly to Indianapolis?

In general, July is the cheapest month to fly from Knoxville to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you are unable to visit Indianapolis during the month of July, then departing from Knoxville during the month August is also very affordable. Most momondo users find prices during this month for around $248.

How have Knoxville to Indianapolis flight prices changed over time?

When to book flights from Knoxville to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Indianapolis (TYS to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Indianapolis

Fastest flight time

4h 01m

Direct flights

None
The fastest flight from Knoxville to Indianapolis takes 4h 01m
There are no direct flights from Knoxville to Indianapolis. There are no popular flight routes from Knoxville to Indianapolis.
Search flight deals

Frequently asked questions about flying from Knoxville to Indianapolis

  • How far is Knoxville McGhee Tyson to Indianapolis by plane?

    Knoxville McGhee Tyson and Indianapolis are 289.8 mi apart from one another. By plane, this route typically takes 4h 01m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Indianapolis Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Indianapolis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Indianapolis Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Indianapolis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The travel and health documents you'll need for your trip to Indianapolis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Indianapolis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Indianapolis?

Best airlines flying from Knoxville to Indianapolis

Compare and see reviews for airlines that fly from Knoxville to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $218Free CancellationRating
7.1
11,923 reviews
Search American Airlines flights
DeltaPriceFrom $228Free CancellationRating
7.8
8,502 reviews
Search Delta flights

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Greenwood
Anderson
Plainfield
Noblesville
Carmel
West Lafayette
Speedway
Fishers
Franklin
Westfield
Seymour
Shelbyville
Brownsburg
Crawfordsville
Greenfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Indianapolis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Indianapolis for you.

Can I find flights from Knoxville to Indianapolis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Indianapolis flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Indianapolis?

momondo provides multiple filters to help you find the best flight to Indianapolis from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Indianapolis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Indianapolis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Indianapolis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 9/12
Sat 9/19
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States