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Cheap flights from Knoxville to Indianapolis from $116

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Indianapolis departing on 6/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Indianapolis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
11:27 am - 2:24 pm
TYS
-
IND
26h 57m
1 stop
Allegiant Air Logo
6:00 am - 9:15 pm
IND
-
TYS
15h 15m
1 stop
$207Allegiant Air
Tue, Jul 7 - Fri, Jul 10
Multiple Airlines Logo
5:56 pm - 9:28 am
TYS
-
IND
15h 32m
1 stop
Multiple Airlines Logo
12:14 pm - 9:50 pm
IND
-
TYS
9h 36m
2 stops
$233Multiple Airlines
Sat, Jun 6 - Mon, Jun 8
Multiple Airlines Logo
11:27 am - 2:24 pm
TYS
-
IND
26h 57m
1 stop
Multiple Airlines Logo
12:20 pm - 10:00 pm
IND
-
TYS
9h 40m
2 stops
$246Multiple Airlines
Tue, Jul 7 - Fri, Jul 10
Multiple Airlines Logo
10:03 pm - 4:49 pm
TYS
-
IND
18h 46m
1 stop
Multiple Airlines Logo
12:14 pm - 9:50 pm
IND
-
TYS
9h 36m
2 stops
$251Multiple Airlines
Fri, Jun 5 - Mon, Jun 8
Allegiant Air Logo
8:00 am - 11:39 pm
TYS
-
IND
15h 39m
1 stop
Allegiant Air Logo
9:00 am - 6:21 pm
IND
-
TYS
9h 21m
1 stop
$254Allegiant Air
Mon, Jun 15 - Wed, Jun 17
Multiple Airlines Logo
9:11 pm - 10:12 am
TYS
-
IND
13h 01m
1 stop
Multiple Airlines Logo
12:20 pm - 10:00 pm
IND
-
TYS
9h 40m
2 stops
$260Multiple Airlines
Thu, Jul 16 - Mon, Jul 20
Allegiant Air Logo
6:00 am - 11:40 am
TYS
-
IND
5h 40m
1 stop
Allegiant Air Logo
9:18 pm - 10:31 pm
IND
-
TYS
25h 13m
1 stop
$271Allegiant Air
Sat, May 30 - Sun, May 31
Allegiant Air Logo
4:20 pm - 2:24 pm
TYS
-
IND
22h 04m
1 stop
Allegiant Air Logo
12:18 pm - 7:50 pm
IND
-
TYS
7h 32m
1 stop
$273Allegiant Air
Tue, Jul 14 - Sat, Jul 18
Multiple Airlines Logo
6:03 pm - 11:25 am
TYS
-
IND
17h 22m
1 stop
Multiple Airlines Logo
12:26 pm - 5:59 pm
IND
-
TYS
29h 33m
1 stop
$274Multiple Airlines
Thu, May 21 - Tue, May 26
Allegiant Air Logo
9:11 pm - 10:12 am
TYS
-
IND
13h 01m
1 stop
Allegiant Air Logo
6:00 am - 9:15 pm
IND
-
TYS
15h 15m
1 stop
$278Allegiant Air
Thu, Jul 16 - Mon, Jul 20

United Airlines flights from Knoxville to Indianapolis

Our best United Airlines deals on Knoxville to Indianapolis flight tickets
United Airlines
May 25
TYS6:30 amKnoxville McGhee Tyson
6h 24m
1 stop
IND12:54 pmIndianapolis
May 25
IND8:13 pmIndianapolis
3h 56m
1 stop
TYS12:09 amKnoxville McGhee Tyson
$321
United Airlines
May 28
TYS5:45 amKnoxville McGhee Tyson
4h 28m
1 stop
IND10:13 amIndianapolis
Jun 1
IND4:25 pmIndianapolis
4h 31m
1 stop
TYS8:56 pmKnoxville McGhee Tyson
$377
United Airlines
May 20
TYS7:00 amKnoxville McGhee Tyson
5h 58m
1 stop
IND12:58 pmIndianapolis
May 20
IND3:40 pmIndianapolis
5h 05m
1 stop
TYS8:45 pmKnoxville McGhee Tyson
$431

Allegiant Air flights from Knoxville to Indianapolis

Our best Allegiant Air deals on Knoxville to Indianapolis flight tickets
Allegiant Air
Jul 7
TYS11:27 amKnoxville McGhee Tyson
26h 57m
1 stop
IND2:24 pmIndianapolis
Jul 10
IND6:00 amIndianapolis
15h 15m
1 stop
TYS9:15 pmKnoxville McGhee Tyson
$207
Allegiant Air
Jun 15
TYS8:00 amKnoxville McGhee Tyson
15h 39m
1 stop
IND11:39 pmIndianapolis
Jun 17
IND9:00 amIndianapolis
9h 21m
1 stop
TYS6:21 pmKnoxville McGhee Tyson
$254
Allegiant Air
May 30
TYS6:00 amKnoxville McGhee Tyson
5h 40m
1 stop
IND11:40 amIndianapolis
May 31
IND9:18 pmIndianapolis
25h 13m
1 stop
TYS10:31 pmKnoxville McGhee Tyson
$271

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 3, 2026.
Use the filters below to find and compare flights from Knoxville to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Tue 7/7

11:27 am-2:24 pm

1 stop26h 57m

Indianapolis

Fri 7/10

6:00 am-9:15 pm

1 stop15h 15m

$207

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Sat 6/6

5:56 pm-9:28 am

1 stop15h 32m

Indianapolis

Mon 6/8

12:14 pm-9:50 pm

2 stops9h 36m

$233

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Tue 7/7

11:27 am-2:24 pm

1 stop26h 57m

Indianapolis

Fri 7/10

12:20 pm-10:00 pm

2 stops9h 40m

$246

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Fri 6/5

10:03 pm-4:49 pm

1 stop18h 46m

Indianapolis

Mon 6/8

12:14 pm-9:50 pm

2 stops9h 36m

$251

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Mon 6/15

8:00 am-11:39 pm

1 stop15h 39m

Indianapolis

Wed 6/17

9:00 am-6:21 pm

1 stop9h 21m

$254
Quickest round-trip

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Thu 7/16

9:11 pm-10:12 am

1 stop13h 01m

Indianapolis

Mon 7/20

12:20 pm-10:00 pm

2 stops9h 40m

$260

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Sat 5/30

6:00 am-11:40 am

1 stop5h 40m

Indianapolis

Sun 5/31

9:18 pm-10:31 pm

1 stop25h 13m

$271

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Tue 7/14

4:20 pm-2:24 pm

1 stop22h 04m

Indianapolis

Sat 7/18

12:18 pm-7:50 pm

1 stop7h 32m

$273

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Thu 5/21

6:03 pm-11:25 am

1 stop17h 22m

Indianapolis

Tue 5/26

12:26 pm-5:59 pm

1 stop29h 33m

$274

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Thu 7/16

9:11 pm-10:12 am

1 stop13h 01m

Indianapolis

Mon 7/20

6:00 am-9:15 pm

1 stop15h 15m

$278

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Indianapolis from

How to get the cheapest flight ticket from Knoxville to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Indianapolis?

What is the cheapest month to fly to Indianapolis?

In general, August is the cheapest month to fly from Knoxville to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $248. If you are unable to visit Indianapolis during the month of August, then departing from Knoxville during the month July is also very affordable. Most momondo users find prices during this month for around $258.

How have Knoxville to Indianapolis flight prices changed over time?

When to book flights from Knoxville to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Indianapolis (TYS to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Indianapolis

Fastest flight time

4h 58m

Direct flights

None
The fastest flight from Knoxville to Indianapolis takes 4h 58m
There are no direct flights from Knoxville to Indianapolis. There are no popular flight routes from Knoxville to Indianapolis.
Search flight deals

Frequently asked questions about flying from Knoxville to Indianapolis

  • How far is Knoxville McGhee Tyson to Indianapolis by plane?

    Knoxville McGhee Tyson and Indianapolis are 289.8 mi apart from one another. By plane, this route typically takes 4h 58m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Indianapolis Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Indianapolis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Indianapolis Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Indianapolis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The travel and health documents you'll need for your trip to Indianapolis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Indianapolis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Indianapolis?

Best airlines flying from Knoxville to Indianapolis

Compare and see reviews for airlines that fly from Knoxville to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $208Free CancellationRating
7.9
8,460 reviews
Search Delta flights
American AirlinesPriceFrom $218Free CancellationRating
7.1
11,672 reviews
Search American Airlines flights

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Plainfield
Anderson
Greenwood
Noblesville
Carmel
Fishers
Franklin
Shelbyville
Speedway
West Lafayette
Westfield
Seymour
Crawfordsville
Brownsburg
Greenfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Indianapolis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Indianapolis for you.

Can I find flights from Knoxville to Indianapolis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Indianapolis flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Indianapolis?

momondo provides multiple filters to help you find the best flight to Indianapolis from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Indianapolis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Indianapolis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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