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Cheap flights from Knoxville to Gainesville from $189

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Gainesville departing on 5/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Gainesville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:40 am - 9:24 amTYS-GNV
3h 44m1 stop
Delta Logo
6:00 am - 11:08 amGNV-TYS
5h 08m1 stop
$224Delta
Find Deal
Sat, Jan 17 - Wed, Jan 21
Delta Logo
5:30 am - 9:24 amTYS-GNV
3h 54m1 stop
Delta Logo
6:00 am - 9:04 amGNV-TYS
3h 04m1 stop
$269Delta
Find Deal
Wed, Feb 18 - Sat, Feb 21
American Airlines Logo
6:53 pm - 11:59 pmTYS-GNV
5h 06m1 stop
American Airlines Logo
8:02 pm - 11:47 pmGNV-TYS
3h 45m1 stop
$274American Airlines
Find Deal
Sat, Dec 20 - Mon, Dec 29
American Airlines Logo
4:04 pm - 11:57 pmTYS-GNV
7h 53m2 stops
American Airlines Logo
7:47 pm - 11:54 pmGNV-TYS
4h 07m1 stop
$284American Airlines
Find Deal
Wed, Feb 18 - Sat, Feb 21
American Airlines Logo
12:15 pm - 6:33 pmTYS-GNV
6h 18m1 stop
American Airlines Logo
6:00 am - 3:20 pmGNV-TYS
9h 20m2 stops
$334American Airlines
Find Deal
Sat, Jan 17 - Wed, Jan 21
American Airlines Logo
3:00 pm - 11:57 pmTYS-GNV
8h 57m2 stops
American Airlines Logo
6:00 am - 3:20 pmGNV-TYS
9h 20m2 stops
$339American Airlines
Find Deal
Sat, Jan 17 - Wed, Jan 21
Delta Logo
8:35 am - 12:58 pmTYS-GNV
4h 23m1 stop
Delta Logo
3:41 pm - 6:58 pmGNV-TYS
3h 17m1 stop
$413Delta
Find Deal
Sat, Dec 13 - Wed, Dec 17
American Airlines Logo
4:31 pm - 10:35 pmTYS-GNV
6h 04m1 stop
American Airlines Logo
6:00 am - 3:14 pmGNV-TYS
9h 14m2 stops
$426American Airlines
Find Deal
Sat, Dec 13 - Wed, Dec 17
American Airlines Logo
5:40 pm - 10:40 pmTYS-GNV
5h 00m1 stop
American Airlines Logo
8:02 pm - 11:47 pmGNV-TYS
3h 45m1 stop
$481American Airlines
Find Deal
Fri, Dec 26 - Fri, Jan 2
American Airlines Logo
6:53 pm - 11:59 pmTYS-GNV
5h 06m1 stop
American Airlines Logo
6:00 am - 12:52 pmGNV-TYS
6h 52m2 stops
$486American Airlines
Find Deal
Sat, Dec 20 - Mon, Dec 29

Delta flights from Knoxville to Gainesville

Our best Delta deals on Knoxville to Gainesville flight tickets
Delta
Jan 17
TYS5:40 amKnoxville McGhee Tyson
3h 44m
1 stop
GNV9:24 amGainesville Regional
Jan 21
GNV6:00 amGainesville Regional
3h 21m
1 stop
TYS9:21 amKnoxville McGhee Tyson
$224
Find similar
Delta
Feb 18
TYS5:30 amKnoxville McGhee Tyson
3h 54m
1 stop
GNV9:24 amGainesville Regional
Feb 21
GNV6:00 amGainesville Regional
3h 04m
1 stop
TYS9:04 amKnoxville McGhee Tyson
$269
Find similar
Delta
Dec 5
TYS10:23 amKnoxville McGhee Tyson
4h 33m
1 stop
GNV2:56 pmGainesville Regional
Dec 8
GNV7:04 pmGainesville Regional
4h 24m
1 stop
TYS11:28 pmKnoxville McGhee Tyson
$299
Find similar

American Airlines flights from Knoxville to Gainesville

Our best American Airlines deals on Knoxville to Gainesville flight tickets
American Airlines
Dec 20
TYS6:53 pmKnoxville McGhee Tyson
5h 06m
1 stop
GNV11:59 pmGainesville Regional
Dec 29
GNV8:02 pmGainesville Regional
3h 45m
1 stop
TYS11:47 pmKnoxville McGhee Tyson
$274
Find similar
American Airlines
Feb 18
TYS4:04 pmKnoxville McGhee Tyson
7h 53m
2 stops
GNV11:57 pmGainesville Regional
Feb 21
GNV7:47 pmGainesville Regional
4h 07m
1 stop
TYS11:54 pmKnoxville McGhee Tyson
$284
Find similar
American Airlines
Jan 17
TYS12:15 pmKnoxville McGhee Tyson
6h 18m
1 stop
GNV6:33 pmGainesville Regional
Jan 21
GNV6:00 amGainesville Regional
9h 20m
2 stops
TYS3:20 pmKnoxville McGhee Tyson
$334
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 30, 2025.
Use the filters below to find and compare flights from Knoxville to Gainesville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 1/17

5:40 am-9:24 am

1 stop3h 44m

Gainesville Regional

Wed 1/21

6:00 am-11:08 am

1 stop5h 08m

$224

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Wed 2/18

5:30 am-9:24 am

1 stop3h 54m

Gainesville Regional

Sat 2/21

6:00 am-9:04 am

1 stop3h 04m

$269

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 12/20

6:53 pm-11:59 pm

1 stop5h 06m

Gainesville Regional

Mon 12/29

8:02 pm-11:47 pm

1 stop3h 45m

$274

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Wed 2/18

4:04 pm-11:57 pm

2 stops7h 53m

Gainesville Regional

Sat 2/21

7:47 pm-11:54 pm

1 stop4h 07m

$284

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 1/17

12:15 pm-6:33 pm

1 stop6h 18m

Gainesville Regional

Wed 1/21

6:00 am-3:20 pm

2 stops9h 20m

$334

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 1/17

3:00 pm-11:57 pm

2 stops8h 57m

Gainesville Regional

Wed 1/21

6:00 am-3:20 pm

2 stops9h 20m

$339

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 12/13

8:35 am-12:58 pm

1 stop4h 23m

Gainesville Regional

Wed 12/17

3:41 pm-6:58 pm

1 stop3h 17m

$413

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 12/13

4:31 pm-10:35 pm

1 stop6h 04m

Gainesville Regional

Wed 12/17

6:00 am-3:14 pm

2 stops9h 14m

$426

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 12/26

5:40 pm-10:40 pm

1 stop5h 00m

Gainesville Regional

Fri 1/2

8:02 pm-11:47 pm

1 stop3h 45m

$481

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 12/20

6:53 pm-11:59 pm

1 stop5h 06m

Gainesville Regional

Mon 12/29

6:00 am-12:52 pm

2 stops6h 52m

$486

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Gainesville from

How to get the cheapest flight ticket from Knoxville to Gainesville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Gainesville?

The cheapest day to depart on your flight to Gainesville is on a Tuesday when prices can be found for as low as $430. This is often the case because there is less demand to fly during this day of the week. Flights from Knoxville to Gainesville on a Friday will generally be more expensive and average around $550. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Gainesville?

In the morning is the cheapest time of day to fly from Knoxville to Gainesville when you can find flight prices for as low as $477. Flying to Gainesville in the morning is an ideal time because this is during off-peak travel hours. Flights to Gainesville are more costly in the afternoon, with an average ticket price of $488. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Knoxville McGhee Tyson to Gainesville Regional flight route?

Fly from Knoxville McGhee Tyson to Gainesville Regional for the best Knoxville McGhee Tyson - Gainesville Regional flight prices

What cabin class options are available on Knoxville McGhee Tyson to Gainesville Regional flights?

There is only 1 cabin class available to choose from on Knoxville McGhee Tyson to Gainesville Regional flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Gainesville flights?

You could potentially save up to 19% on your flight if you consider stops on a Knoxville to Gainesville flight.

When to book flights from Knoxville to Gainesville

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Gainesville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Gainesville (TYS to GNV) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Gainesville

Fastest flight time

3h 44m

Direct flights

None
The fastest flight from Knoxville to Gainesville takes 3h 44m
There are no direct flights from Knoxville to Gainesville. There are no popular flight routes from Knoxville to Gainesville.
Search flight deals

  • How far is Knoxville McGhee Tyson to Gainesville Regional by plane?

    The distance between Knoxville McGhee Tyson and Gainesville Regional is about 445.3 mi. Flights usually cover this in 3h 44m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Gainesville Regional Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Gainesville Regional Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Gainesville Regional Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Gainesville Regional Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Gainesville Regional Airport.

  • What documentation or ID do you need to fly to Gainesville Regional Airport?

    The required travel and health documents for your Gainesville Regional Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Gainesville Regional Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Gainesville?

Best airlines flying from Knoxville to Gainesville

Compare and see reviews for airlines that fly from Knoxville to Gainesville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $228Free CancellationRating
7.9
8,011 reviews
Search Delta flights

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua
Trenton

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Gainesville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Gainesville. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Gainesville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Gainesville from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Gainesville?

momondo helps you find the best flight between Knoxville and Gainesville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Gainesville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Gainesville, momondo offers a useful price alert feature which will track prices for flights to Gainesville from Knoxville and alert you when they change.

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