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Cheap flights from Knoxville to Gainesville from $347

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Gainesville departing on 9/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Knoxville to Gainesville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 9:31 am
TYS
-
GNV
3h 31m
1 stop
Delta Logo
6:57 pm - 11:55 pm
GNV
-
TYS
4h 58m
1 stop
$347Delta
Tue, Sep 8 - Tue, Sep 15
Delta Logo
6:00 am - 9:18 am
TYS
-
GNV
3h 18m
1 stop
Delta Logo
7:01 pm - 11:52 pm
GNV
-
TYS
4h 51m
1 stop
$353Delta
Sat, Aug 1 - Tue, Aug 4
Delta Logo
12:06 pm - 6:13 pm
TYS
-
GNV
6h 07m
1 stop
Delta Logo
7:00 pm - 11:59 pm
GNV
-
TYS
4h 59m
1 stop
$359Delta
Fri, Oct 16 - Mon, Oct 19
Delta Logo
7:25 pm - 10:45 pm
TYS
-
GNV
3h 20m
1 stop
Delta Logo
6:03 am - 11:01 am
GNV
-
TYS
4h 58m
1 stop
$399Delta
Fri, Oct 9 - Sun, Oct 11
Delta Logo
12:06 pm - 6:13 pm
TYS
-
GNV
6h 07m
1 stop
Delta Logo
10:05 am - 5:36 pm
GNV
-
TYS
7h 31m
1 stop
$433Delta
Fri, Oct 16 - Sun, Oct 18
American Airlines Logo
6:05 pm - 9:51 pm
TYS
-
GNV
3h 46m
1 stop
American Airlines Logo
6:00 am - 3:22 pm
GNV
-
TYS
9h 22m
2 stops
$436American Airlines
Tue, Sep 8 - Tue, Sep 15
American Airlines Logo
8:05 pm - 12:16 am
TYS
-
GNV
4h 11m
1 stop
American Airlines Logo
6:00 am - 3:42 pm
GNV
-
TYS
9h 42m
2 stops
$442American Airlines
Sat, Aug 1 - Tue, Aug 4
Delta Logo
5:40 am - 9:28 am
TYS
-
GNV
3h 48m
1 stop
Delta Logo
6:33 am - 11:10 am
GNV
-
TYS
4h 37m
1 stop
$447Delta
Fri, Jul 17 - Tue, Jul 21
American Airlines Logo
4:52 pm - 10:26 pm
TYS
-
GNV
5h 34m
1 stop
American Airlines Logo
7:34 pm - 11:55 pm
GNV
-
TYS
4h 21m
1 stop
$482American Airlines
Fri, Oct 9 - Mon, Oct 12
American Airlines Logo
8:05 pm - 12:16 am
TYS
-
GNV
4h 11m
1 stop
American Airlines Logo
6:00 am - 12:34 pm
GNV
-
TYS
6h 34m
2 stops
$486American Airlines
Fri, Jul 17 - Tue, Jul 21

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Delta flights from Knoxville to Gainesville

Our best Delta deals on Knoxville to Gainesville flight tickets
Delta
Sep 8
TYS6:00 amKnoxville McGhee Tyson
3h 31m
1 stop
GNV9:31 amGainesville Regional
Sep 15
GNV6:57 pmGainesville Regional
4h 58m
1 stop
TYS11:55 pmKnoxville McGhee Tyson
$347
Delta
Aug 1
TYS6:00 amKnoxville McGhee Tyson
3h 18m
1 stop
GNV9:18 amGainesville Regional
Aug 4
GNV7:01 pmGainesville Regional
4h 51m
1 stop
TYS11:52 pmKnoxville McGhee Tyson
$353
Delta
Oct 16
TYS5:45 amKnoxville McGhee Tyson
3h 34m
1 stop
GNV9:19 amGainesville Regional
Oct 17
GNV1:29 pmGainesville Regional
4h 07m
1 stop
TYS5:36 pmKnoxville McGhee Tyson
$359

American Airlines flights from Knoxville to Gainesville

Our best American Airlines deals on Knoxville to Gainesville flight tickets
American Airlines
Aug 2
TYS5:00 amKnoxville McGhee Tyson
4h 05m
1 stop
GNV9:05 amGainesville Regional
Aug 8
GNV6:39 pmGainesville Regional
4h 19m
1 stop
TYS10:58 pmKnoxville McGhee Tyson
$373
American Airlines
Sep 8
TYS6:05 pmKnoxville McGhee Tyson
3h 46m
1 stop
GNV9:51 pmGainesville Regional
Sep 15
GNV6:00 amGainesville Regional
9h 22m
2 stops
TYS3:22 pmKnoxville McGhee Tyson
$436
American Airlines
Aug 1
TYS8:05 pmKnoxville McGhee Tyson
4h 11m
1 stop
GNV12:16 amGainesville Regional
Aug 4
GNV6:00 amGainesville Regional
9h 42m
2 stops
TYS3:42 pmKnoxville McGhee Tyson
$442

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 6, 2026.
Use the filters below to find and compare flights from Knoxville to Gainesville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Tue 9/8

6:00 am-9:31 am

1 stop3h 31m

Gainesville Regional

Tue 9/15

6:57 pm-11:55 pm

1 stop4h 58m

$347
Quickest round-trip

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 8/1

6:00 am-9:18 am

1 stop3h 18m

Gainesville Regional

Tue 8/4

7:01 pm-11:52 pm

1 stop4h 51m

$353

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 10/16

12:06 pm-6:13 pm

1 stop6h 07m

Gainesville Regional

Mon 10/19

7:00 pm-11:59 pm

1 stop4h 59m

$359

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 10/9

7:25 pm-10:45 pm

1 stop3h 20m

Gainesville Regional

Sun 10/11

6:03 am-11:01 am

1 stop4h 58m

$399

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 10/16

12:06 pm-6:13 pm

1 stop6h 07m

Gainesville Regional

Sun 10/18

10:05 am-5:36 pm

1 stop7h 31m

$433

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Tue 9/8

6:05 pm-9:51 pm

1 stop3h 46m

Gainesville Regional

Tue 9/15

6:00 am-3:22 pm

2 stops9h 22m

$436

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Sat 8/1

8:05 pm-12:16 am

1 stop4h 11m

Gainesville Regional

Tue 8/4

6:00 am-3:42 pm

2 stops9h 42m

$442

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 7/17

5:40 am-9:28 am

1 stop3h 48m

Gainesville Regional

Tue 7/21

6:33 am-11:10 am

1 stop4h 37m

$447

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 10/9

4:52 pm-10:26 pm

1 stop5h 34m

Gainesville Regional

Mon 10/12

7:34 pm-11:55 pm

1 stop4h 21m

$482

KnoxvilleGainesville

TYS - GNV

TYSGNV

Knoxville McGhee Tyson

Fri 7/17

8:05 pm-12:16 am

1 stop4h 11m

Gainesville Regional

Tue 7/21

6:00 am-12:34 pm

2 stops6h 34m

$486

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Gainesville from

How to get the cheapest flight ticket from Knoxville to Gainesville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Knoxville to Gainesville flights?

You could potentially save up to 23% on your flight if you consider stops on a Knoxville to Gainesville flight.

When to book flights from Knoxville to Gainesville

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Gainesville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Gainesville (TYS to GNV) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Gainesville

Fastest flight time

3h 31m

Direct flights

None
The fastest flight from Knoxville to Gainesville takes 3h 31m
There are no direct flights from Knoxville to Gainesville. There are no popular flight routes from Knoxville to Gainesville.
Search flight deals

Frequently asked questions about flying from Knoxville to Gainesville

  • How far is Knoxville McGhee Tyson to Gainesville Regional by plane?

    The distance between Knoxville McGhee Tyson and Gainesville Regional is about 445.3 mi. Flights usually cover this in 3h 31m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Gainesville Regional Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Gainesville Regional Airport are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Gainesville Regional Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Gainesville Regional Airport.

  • What documentation or ID do you need to fly to Gainesville Regional Airport?

    The required travel and health documents for your Gainesville Regional Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Gainesville Regional Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Gainesville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Gainesville. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Gainesville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Gainesville from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Gainesville?

momondo helps you find the best flight between Knoxville and Gainesville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Gainesville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Gainesville, momondo offers a useful price alert feature which will track prices for flights to Gainesville from Knoxville and alert you when they change.

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