Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Knoxville to Fort Myers from $160

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Fort Myers departing on 7/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Knoxville to Fort Myers

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:40 pm - 8:30 pm
TYS
-
RSW
4h 50m
1 stop
American Airlines Logo
3:59 pm - 10:23 pm
RSW
-
TYS
6h 24m
1 stop
$285American Airlines
Di, Jun 30 - Di, Jul 7
American Airlines Logo
5:00 am - 9:07 am
TYS
-
RSW
4h 07m
1 stop
American Airlines Logo
7:41 pm - 11:51 pm
RSW
-
TYS
4h 10m
1 stop
$302American Airlines
Fr, Jul 3 - Mo, Jul 6
Southwest Logo
7:00 am - 1:55 pm
TYS
-
RSW
6h 55m
1 stop
Southwest Logo
10:30 am - 7:50 pm
RSW
-
TYS
9h 20m
2 stops
$307Southwest
Mi, Nov 18 - Mi, Dez 2
American Airlines Logo
10:00 am - 3:09 pm
TYS
-
RSW
5h 09m
1 stop
American Airlines Logo
6:22 am - 10:38 am
RSW
-
TYS
4h 16m
1 stop
$317American Airlines
Mi, Jul 29 - Sa, Aug 1
Southwest Logo
6:40 am - 4:30 pm
TYS
-
RSW
9h 50m
1 stop
Southwest Logo
8:45 am - 7:50 pm
RSW
-
TYS
11h 05m
2 stops
$318Southwest
Fr, Jul 31 - Di, Aug 4
American Airlines Logo
5:00 am - 9:08 am
TYS
-
RSW
4h 08m
1 stop
American Airlines Logo
7:41 pm - 11:51 pm
RSW
-
TYS
4h 10m
1 stop
$319American Airlines
Sa, Jul 4 - Sa, Jul 11
Delta Logo
7:43 pm - 12:23 am
TYS
-
RSW
4h 40m
1 stop
Delta Logo
5:35 am - 9:40 am
RSW
-
TYS
4h 05m
1 stop
$326Delta
Di, Jul 28 - Mo, Aug 3
Southwest Logo
12:40 pm - 10:00 pm
TYS
-
RSW
9h 20m
1 stop
Southwest Logo
8:55 am - 6:35 pm
RSW
-
TYS
9h 40m
1 stop
$330Southwest
Fr, Aug 7 - Fr, Aug 14
Delta Logo
10:26 am - 4:44 pm
TYS
-
RSW
6h 18m
1 stop
Delta Logo
6:45 am - 11:10 am
RSW
-
TYS
4h 25m
1 stop
$331Delta
Fr, Jul 24 - So, Jul 26
Delta Logo
5:40 am - 12:11 pm
TYS
-
RSW
6h 31m
1 stop
Delta Logo
5:35 am - 11:10 am
RSW
-
TYS
5h 35m
1 stop
$341Delta
Mo, Jul 27 - Do, Jul 30

Southwest flights from Knoxville to Fort Myers

Our best Southwest deals on Knoxville to Fort Myers flight tickets
Southwest
Nov 18
TYS7:00 amKnoxville McGhee Tyson
6h 55m
1 stop
RSW1:55 pmFort Myers SW Florida Intl
Dec 2
RSW10:30 amFort Myers SW Florida Intl
9h 20m
2 stops
TYS7:50 pmKnoxville McGhee Tyson
$307
Southwest
Jul 31
TYS6:40 amKnoxville McGhee Tyson
9h 50m
1 stop
RSW4:30 pmFort Myers SW Florida Intl
Aug 4
RSW8:45 amFort Myers SW Florida Intl
11h 05m
2 stops
TYS7:50 pmKnoxville McGhee Tyson
$318
Southwest
Aug 7
TYS12:40 pmKnoxville McGhee Tyson
9h 20m
1 stop
RSW10:00 pmFort Myers SW Florida Intl
Aug 14
RSW8:55 amFort Myers SW Florida Intl
11h 00m
2 stops
TYS7:55 pmKnoxville McGhee Tyson
$330

Delta flights from Knoxville to Fort Myers

Our best Delta deals on Knoxville to Fort Myers flight tickets
Delta
Jul 28
TYS7:43 pmKnoxville McGhee Tyson
4h 40m
1 stop
RSW12:23 amFort Myers SW Florida Intl
Aug 2
RSW5:35 amFort Myers SW Florida Intl
4h 01m
1 stop
TYS9:36 amKnoxville McGhee Tyson
$326
Delta
Jul 24
TYS10:26 amKnoxville McGhee Tyson
6h 18m
1 stop
RSW4:44 pmFort Myers SW Florida Intl
Jul 26
RSW6:45 amFort Myers SW Florida Intl
4h 25m
1 stop
TYS11:10 amKnoxville McGhee Tyson
$331
Delta
Jul 27
TYS5:40 amKnoxville McGhee Tyson
6h 31m
1 stop
RSW12:11 pmFort Myers SW Florida Intl
Jul 31
RSW5:35 amFort Myers SW Florida Intl
4h 01m
1 stop
TYS9:36 amKnoxville McGhee Tyson
$341

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated Juni 6, 2026.
Use the filters below to find and compare flights from Knoxville to Fort Myers that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Di 6/30

3:40 pm-8:30 pm

1 stop4h 50m

Fort Myers SW Florida Intl

Di 7/7

3:59 pm-10:23 pm

1 stop6h 24m

$285
Quickest round-trip

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Fr 7/3

5:00 am-9:07 am

1 stop4h 07m

Fort Myers SW Florida Intl

Mo 7/6

7:41 pm-11:51 pm

1 stop4h 10m

$302

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Mi 11/18

7:00 am-1:55 pm

1 stop6h 55m

Fort Myers SW Florida Intl

Mi 12/2

10:30 am-7:50 pm

2 stops9h 20m

$307

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Mi 7/29

10:00 am-3:09 pm

1 stop5h 09m

Fort Myers SW Florida Intl

Sa 8/1

6:22 am-10:38 am

1 stop4h 16m

$317

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Fr 7/31

6:40 am-4:30 pm

1 stop9h 50m

Fort Myers SW Florida Intl

Di 8/4

8:45 am-7:50 pm

2 stops11h 05m

$318

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Sa 7/4

5:00 am-9:08 am

1 stop4h 08m

Fort Myers SW Florida Intl

Sa 7/11

7:41 pm-11:51 pm

1 stop4h 10m

$319

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Di 7/28

7:43 pm-12:23 am

1 stop4h 40m

Fort Myers SW Florida Intl

Mo 8/3

5:35 am-9:40 am

1 stop4h 05m

$326

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Fr 8/7

12:40 pm-10:00 pm

1 stop9h 20m

Fort Myers SW Florida Intl

Fr 8/14

8:55 am-6:35 pm

1 stop9h 40m

$330

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Fr 7/24

10:26 am-4:44 pm

1 stop6h 18m

Fort Myers SW Florida Intl

So 7/26

6:45 am-11:10 am

1 stop4h 25m

$331

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Mo 7/27

5:40 am-12:11 pm

1 stop6h 31m

Fort Myers SW Florida Intl

Do 7/30

5:35 am-11:10 am

1 stop5h 35m

$341

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Fort Myers from

How to get the cheapest flight ticket from Knoxville to Fort Myers

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Fort Myers?

What is the cheapest month to fly to Fort Myers?

In general, February is the cheapest month to fly from Knoxville to Fort Myers. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $180. If you are unable to visit Fort Myers during the month of February, then departing from Knoxville during the month August is also very affordable. Most momondo users find prices during this month for around $253.

Can stopping save me money on Knoxville to Fort Myers flights?

You could potentially save up to 37% on your flight if you consider stops on a Knoxville to Fort Myers flight.

How have Knoxville to Fort Myers flight prices changed over time?

As of June 2026, prices for Knoxville to Fort Myers flights are approximately 25% cheaper when compared to flights at the same time last year.

When to book flights from Knoxville to Fort Myers

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Fort Myers according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Fort Myers (TYS to RSW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Fort Myers

Fastest flight time

4h 03m

Direct flights

None
The fastest flight from Knoxville to Fort Myers takes 4h 03m
There are no direct flights from Knoxville to Fort Myers. There are no popular flight routes from Knoxville to Fort Myers.
Search flight deals

Frequently asked questions about flying from Knoxville to Fort Myers

  • How far is Knoxville McGhee Tyson to Fort Myers SW Florida Intl by plane?

    Fort Myers SW Florida Intl is 654.7 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 4h 03m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport.

  • What documentation or ID do you need to fly to Fort Myers SW Florida Intl Airport?

    The required travel and health documents for your Fort Myers SW Florida Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Fort Myers SW Florida Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Fort Myers?

Best airlines flying from Knoxville to Fort Myers

Compare and see reviews for airlines that fly from Knoxville to Fort Myers with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,651 reviews
Search American Airlines flights
DeltaPriceFrom $253Free CancellationRating
7.8
8,395 reviews
Search Delta flights

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Fort Myers Beach
Sanibel
Cape Coral
Captiva
Estero
Boca Grande
Lehigh Acres
North Fort Myers

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Fort Myers?

It is quick and easy to find Knoxville to Fort Myers flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Fort Myers that suits you.

Can I find flights from Knoxville to Fort Myers with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Fort Myers flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Fort Myers?

Once you have performed a search for Knoxville to Fort Myers flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to Fort Myers right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Fort Myers flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Fort Myers trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mo 7/6
Mo 7/13
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States