What airlines fly to Fort Myers?

Allegiant Air, Delta and American Airlines are the top three most popular airlines that fly to Fort Myers from Knoxville according to our data. Allegiant Air is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Fort Myers. Keep in mind that there are 3 different airlines that fly to Fort Myers on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from Knoxville to Fort Myers?

Charlotte (CLT) has the shortest average layover time for this route: 0h 40m.

Which layover airport has the shortest travel time from Knoxville to Fort Myers?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 3h 47m.

Which airport is the most popular layover for flights between Knoxville and Fort Myers?

Atlanta (ATL) was the most common stop: 60% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Knoxville to Fort Myers?

Flights via Charlotte (CLT) offer the lowest average round-trip price of $305.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Fort Myers SW Florida Intl?

Delta, United Airlines, and American Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Fort Myers SW Florida Intl

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport?

The number of operators available for flights from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport is 2 as of August 2025.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport.

What documentation or ID do you need to fly to Fort Myers SW Florida Intl Airport?

The required travel and health documents for your Fort Myers SW Florida Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Fort Myers SW Florida Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$130 Cheap Flights from Knoxville to Fort Myers (TYS-RSW) in 2025

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Find the cheapest flights from Knoxville to Fort Myers (TYS-RSW)

Round-trip

One-way

Last minute

Cheap round-trip flights

6:36 pm - 12:21 amTYS-RSW

5h 45m1 stop

5:40 pm - 11:44 pmRSW-TYS

6h 04m1 stop

$279Delta

Find Deal

Tue, Dec 30 - Wed, Jan 7

8:15 am - 1:09 pmTYS-RSW

4h 54m1 stop

5:40 pm - 11:44 pmRSW-TYS

6h 04m1 stop

$299Delta

Find Deal

Wed, Dec 31 - Wed, Jan 7

9:50 am - 4:00 pmTYS-RSW

6h 10m1 stop

6:40 pm - 11:59 pmRSW-TYS

5h 19m1 stop

$334United Airlines

Find Deal

Thu, Nov 20 - Sun, Nov 23

5:45 am - 2:19 pmTYS-RSW

8h 34m2 stops

6:40 pm - 11:59 pmRSW-TYS

5h 19m1 stop

$339United Airlines

Find Deal

Thu, Nov 20 - Sun, Nov 23

8:04 pm - 12:27 amTYS-RSW

4h 23m1 stop

7:21 pm - 11:51 pmRSW-TYS

4h 30m1 stop

$415American Airlines

Find Deal

Sun, Nov 2 - Sun, Nov 9

9:15 pm - 9:16 pmTYS-RSW

24h 01m2 stops

4:14 pm - 3:36 pmRSW-TYS

23h 22m3 stops

$474

Find Deal

Thu, Oct 2 - Tue, Oct 7

8:17 pm - 11:32 amTYS-RSW

15h 15m2 stops

9:11 pm - 7:32 pmRSW-TYS

22h 21m2 stops

$512Frontier

Find Deal

Fri, Oct 17 - Thu, Oct 23

9:15 pm - 9:16 pmTYS-RSW

24h 01m3 stops

4:14 pm - 3:36 pmRSW-TYS

23h 22m3 stops

$515

Find Deal

Thu, Oct 2 - Tue, Oct 7

8:17 pm - 11:32 amTYS-RSW

15h 15m2 stops

10:16 pm - 7:32 pmRSW-TYS

21h 16m2 stops

$602Frontier

Find Deal

Fri, Oct 10 - Sun, Oct 12

6:11 pm - 11:33 pmTYS-RSW

5h 22m1 stop

12:00 pm - 7:01 pmRSW-TYS

7h 01m2 stops

$631American Airlines

Find Deal

Fri, Oct 10 - Wed, Oct 15

United Airlines flights from Knoxville to Fort Myers

Our best United Airlines deals on Knoxville to Fort Myers flight tickets

United Airlines

Sep 2

TYS7:00 amKnoxville McGhee Tyson

7h 44m

1 stop

RSW2:44 pmFort Myers SW Florida Intl

Sep 13

RSW6:25 pmFort Myers SW Florida Intl

5h 32m

1 stop

TYS11:57 pmKnoxville McGhee Tyson

$328

Find similar

United Airlines

Nov 20

TYS9:50 amKnoxville McGhee Tyson

6h 10m

1 stop

RSW4:00 pmFort Myers SW Florida Intl

Nov 23

RSW6:40 pmFort Myers SW Florida Intl

5h 19m

1 stop

TYS11:59 pmKnoxville McGhee Tyson

$334

Find similar

United Airlines

Nov 20

TYS5:45 amKnoxville McGhee Tyson

8h 34m

2 stops

RSW2:19 pmFort Myers SW Florida Intl

Nov 23

RSW6:40 pmFort Myers SW Florida Intl

5h 19m

1 stop

TYS11:59 pmKnoxville McGhee Tyson

$339

Find similar

Delta flights from Knoxville to Fort Myers

Our best Delta deals on Knoxville to Fort Myers flight tickets

Delta

Dec 30

TYS6:36 pmKnoxville McGhee Tyson

5h 45m

1 stop

RSW12:21 amFort Myers SW Florida Intl

Jan 7

RSW5:40 pmFort Myers SW Florida Intl

6h 04m

1 stop

TYS11:44 pmKnoxville McGhee Tyson

$279

Find similar

Delta

Dec 31

TYS8:15 amKnoxville McGhee Tyson

4h 54m

1 stop

RSW1:09 pmFort Myers SW Florida Intl

Jan 7

RSW5:40 pmFort Myers SW Florida Intl

6h 04m

1 stop

TYS11:44 pmKnoxville McGhee Tyson

$299

Find similar

Delta

Oct 2

TYS5:45 amKnoxville McGhee Tyson

4h 02m

1 stop

RSW9:47 amFort Myers SW Florida Intl

Oct 7

RSW8:14 amFort Myers SW Florida Intl

5h 28m

1 stop

TYS1:42 pmKnoxville McGhee Tyson

$313

Find similar

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Tue 12/30

6:36 pm-12:21 am

1 stop5h 45m

Fort Myers SW Florida Intl

Wed 1/7

5:40 pm-11:44 pm

1 stop6h 04m

$279

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Wed 12/31

8:15 am-1:09 pm

1 stop4h 54m

Fort Myers SW Florida Intl

Wed 1/7

5:40 pm-11:44 pm

1 stop6h 04m

$299

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Thu 11/20

9:50 am-4:00 pm

1 stop6h 10m

Fort Myers SW Florida Intl

Sun 11/23

6:40 pm-11:59 pm

1 stop5h 19m

$334

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Thu 11/20

5:45 am-2:19 pm

2 stops8h 34m

Fort Myers SW Florida Intl

Sun 11/23

6:40 pm-11:59 pm

1 stop5h 19m

$339

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Sun 11/2

8:04 pm-12:27 am

1 stop4h 23m

Fort Myers SW Florida Intl

Sun 11/9

7:21 pm-11:51 pm

1 stop4h 30m

$415

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Thu 10/2

9:15 pm-9:16 pm

2 stops24h 01m

Fort Myers SW Florida Intl

Tue 10/7

4:14 pm-3:36 pm

3 stops23h 22m

$474

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Fri 10/17

8:17 pm-11:32 am

2 stops15h 15m

Fort Myers SW Florida Intl

Thu 10/23

9:11 pm-7:32 pm

2 stops22h 21m

$512

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Thu 10/2

9:15 pm-9:16 pm

3 stops24h 01m

Fort Myers SW Florida Intl

Tue 10/7

4:14 pm-3:36 pm

3 stops23h 22m

$515

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Fri 10/10

8:17 pm-11:32 am

2 stops15h 15m

Fort Myers SW Florida Intl

Sun 10/12

10:16 pm-7:32 pm

2 stops21h 16m

$602

KnoxvilleFort Myers

TYS - RSW

TYSRSW

Knoxville McGhee Tyson

Fri 10/10

6:11 pm-11:33 pm

1 stop5h 22m

Fort Myers SW Florida Intl

Wed 10/15

12:00 pm-7:01 pm

2 stops7h 01m

$631

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Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Fort Myers

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Fort Myers?

In general, September is the cheapest month to fly from Knoxville to Fort Myers. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $251. If you are unable to visit Fort Myers during the month of September, then departing from Knoxville during the month January is also very affordable. Most momondo users find prices during this month for around $283.

What is the cheapest day to depart on your flight to Fort Myers?

The cheapest day to depart from Knoxville to Fort Myers is on a Wednesday when prices can be found for as low as $283. Flights from Knoxville to Fort Myers on a Sunday will generally be more expensive and average around $496. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Fort Myers?

The cheapest time of day to fly to Fort Myers is in the evening when flights can be purchased for as low as $286. Flights in the morning are often more expensive with an average ticket price of $358.

How have Knoxville to Fort Myers flight prices changed over time?

When to book flights from Knoxville to Fort Myers

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Fort Myers according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Fort Myers (TYS to RSW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Fort Myers

Direct flights	None

There are no direct flights from Knoxville to Fort Myers. There are no popular flight routes from Knoxville to Fort Myers.

Search flight deals

How far is Knoxville McGhee Tyson to Fort Myers SW Florida Intl by plane?
Fort Myers SW Florida Intl is 654.7 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 4h 02m.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport?
The number of operators available for flights from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport is 2 as of August 2025.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport.
What documentation or ID do you need to fly to Fort Myers SW Florida Intl Airport?
The required travel and health documents for your Fort Myers SW Florida Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Fort Myers SW Florida Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Knoxville to Fort Myers?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Knoxville to Fort Myers is American Airlines (58% of total bookings). The next most popular airline is Delta (42%).

Best airlines flying from Knoxville to Fort Myers

Compare and see reviews for airlines that fly from Knoxville to Fort Myers with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $223	Free Cancellation	Rating 7.9 7,981 reviews		Search Delta flights
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 10,000 reviews		Search American Airlines flights

Sanibel

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Cape Coral

Captiva

Estero

North Fort Myers

Boca Grande

Lehigh Acres

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Why should I use momondo to find a flight deal from Knoxville to Fort Myers?

It is quick and easy to find Knoxville to Fort Myers flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Fort Myers that suits you.

Can I find flights from Knoxville to Fort Myers with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Fort Myers flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Fort Myers?

Once you have performed a search for Knoxville to Fort Myers flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to Fort Myers right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Fort Myers flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Fort Myers trip

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Cheap flights from Knoxville to Fort Myers from $130

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Fort Myers departing on 10/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Knoxville to Fort Myers

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Fort Myers?

What is the cheapest day to depart on your flight to Fort Myers?

What is the cheapest time of day to depart on your flight to Fort Myers?

The cheapest time of day to fly to Fort Myers is in the evening when flights can be purchased for as low as $286. Flights in the morning are often more expensive with an average ticket price of $358.

How have Knoxville to Fort Myers flight prices changed over time?

What is the cheapest airline that flies from Knoxville McGhee Tyson to Fort Myers SW Florida Intl?

Delta, United Airlines, and American Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Fort Myers SW Florida Intl

What airlines fly to Fort Myers?

Which airport is the most popular layover for flights between Knoxville and Fort Myers?

Atlanta (ATL) was the most common stop: 60% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Knoxville to Fort Myers?

Flights via Charlotte (CLT) offer the lowest average round-trip price of $305.

Which layover airport has the shortest travel time from Knoxville to Fort Myers?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 3h 47m.

Which layover airport has the shortest connection time from Knoxville to Fort Myers?

Charlotte (CLT) has the shortest average layover time for this route: 0h 40m.

When to book flights from Knoxville to Fort Myers

Cheap Knoxville to Fort Myers (TYS to RSW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Fort Myers

Direct flights

How far is Knoxville McGhee Tyson to Fort Myers SW Florida Intl by plane?

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport?

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport?

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Fort Myers SW Florida Intl Airport?

What documentation or ID do you need to fly to Fort Myers SW Florida Intl Airport?

What is the most popular airline from Knoxville to Fort Myers?

Best airlines flying from Knoxville to Fort Myers

Compare and see reviews for airlines that fly from Knoxville to Fort Myers with momondo

Traveling to a place near Fort Myers?

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Fort Myers?

Can I find flights from Knoxville to Fort Myers with flexible booking policies on momondo?

How can momondo help me find flights from Knoxville to Fort Myers?

I’m not ready to book a flight from Knoxville to Fort Myers right now. Can momondo alert me if prices change?

An easier way to manage your Fort Myers trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Florida