What airlines fly to Florida Keys?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to Florida Keys from Knoxville according to our data. Allegiant Air is the first choice among our users, with 56% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

How many flights depart from Knoxville to Florida Keys on average per day?

As of February 2026, there are 2 flights per day flying from Knoxville to Florida Keys. The most common time of day flights depart is 8:00AM, with 100% of flights taking off at noon.

How many flights depart from Knoxville to Florida Keys on average per week?

As of February 2026, there are 16 flights per week flying from Knoxville to Florida Keys. The most common day of the week flights depart is Mon, with 19% of flights taking off on this day.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Florida Keys?

Southwest and Allegiant Air are the most popular carriers operating from Knoxville McGhee Tyson to Florida Keys

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Florida Keys?

Prices for flights from Knoxville McGhee Tyson Airport to Florida Keys refresh daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Florida Keys?

As of February 2026, there are 4 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Florida Keys.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Florida Keys?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The travel and health documents required for your trip to Florida Keys can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florida Keys. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$62 Cheap Flights from Knoxville to Florida Keys in 2026

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Find the cheapest flights from Knoxville to Florida Keys

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One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

8:00 am - 10:11 am

TYS

EYW

2h 11mnonstop

11:01 am - 1:16 pm

EYW

TYS

2h 15mnonstop

$83Allegiant Air

Mon, Mar 23 - Fri, Mar 27

8:00 am - 10:11 am

TYS

EYW

2h 11mnonstop

11:01 am - 1:16 pm

EYW

TYS

2h 15mnonstop

$87Allegiant Air

Mon, Mar 23 - Fri, Mar 27

8:00 am - 10:11 am

TYS

EYW

2h 11mnonstop

11:01 am - 1:16 pm

EYW

TYS

2h 15mnonstop

$88Allegiant Air

Mon, Mar 23 - Fri, Mar 27

8:00 am - 10:11 am

TYS

EYW

2h 11mnonstop

11:01 am - 1:16 pm

EYW

TYS

2h 15mnonstop

$90Allegiant Air

Mon, Mar 23 - Fri, Mar 27

4:28 pm - 5:05 am

TYS

MIA

12h 37m

1 stop

7:00 am - 3:33 pm

MIA

TYS

8h 33m

1 stop

$160Frontier

Thu, Apr 23 - Sun, Apr 26

6:00 am - 8:12 am

TYS

MIA

2h 12mnonstop

9:43 pm - 11:59 pm

MIA

TYS

2h 16mnonstop

$199American Airlines

Tue, Mar 24 - Tue, Mar 31

7:05 am - 12:40 pm

TYS

MIA

5h 35m

1 stop

7:20 am - 7:40 pm

MIA

TYS

12h 20m

2 stops

$204Southwest

Tue, Apr 14 - Tue, Apr 21

7:05 am - 5:30 pm

TYS

MIA

10h 25m

2 stops

7:20 am - 7:40 pm

MIA

TYS

12h 20m

2 stops

$209Southwest

Tue, Apr 14 - Tue, Apr 21

6:30 am - 8:38 am

TYS

MIA

2h 08mnonstop

9:45 pm - 11:59 pm

MIA

TYS

2h 14mnonstop

$215American Airlines

Thu, Apr 9 - Tue, Apr 14

7:10 am - 2:10 pm

TYS

MIA

7h 00m

1 stop

12:01 pm - 4:06 pm

MIA

TYS

4h 05m

1 stop

$219Delta

Tue, Mar 24 - Tue, Mar 31

Southwest flights from Knoxville to Florida Keys

Our best Southwest deals on Knoxville to Florida Keys flight tickets

Southwest

Apr 14

TYS7:05 amKnoxville McGhee Tyson

5h 35m

1 stop

MIA12:40 pmMiami

Apr 21

MIA7:20 amMiami

12h 20m

2 stops

TYS7:40 pmKnoxville McGhee Tyson

$204

Southwest

Apr 14

TYS7:05 amKnoxville McGhee Tyson

10h 25m

2 stops

MIA5:30 pmMiami

Apr 21

MIA7:20 amMiami

12h 20m

2 stops

TYS7:40 pmKnoxville McGhee Tyson

$209

Southwest

Mar 25

TYS7:50 amKnoxville McGhee Tyson

6h 35m

1 stop

MIA2:25 pmMiami

Apr 1

MIA6:55 amMiami

10h 45m

1 stop

TYS5:40 pmKnoxville McGhee Tyson

$214

American Airlines flights from Knoxville to Florida Keys

Our best American Airlines deals on Knoxville to Florida Keys flight tickets

American Airlines

Mar 24

TYS6:00 amKnoxville McGhee Tyson

2h 12m

MIA8:12 amMiami

Mar 31

MIA9:43 pmMiami

2h 16m

TYS11:59 pmKnoxville McGhee Tyson

$199

American Airlines

Apr 9

TYS6:30 amKnoxville McGhee Tyson

2h 08m

MIA8:38 amMiami

Apr 14

MIA9:45 pmMiami

2h 14m

TYS11:59 pmKnoxville McGhee Tyson

$215

American Airlines

Apr 9

TYS2:06 pmKnoxville McGhee Tyson

6h 41m

1 stop

MIA8:47 pmMiami

Apr 14

MIA9:45 pmMiami

2h 14m

TYS11:59 pmKnoxville McGhee Tyson

$225

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Mon 3/23

8:00 am-10:11 am

Nonstop2h 11m

Key West

Fri 3/27

11:01 am-1:16 pm

Nonstop2h 15m

$83

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Mon 3/23

8:00 am-10:11 am

Nonstop2h 11m

Key West

Fri 3/27

11:01 am-1:16 pm

Nonstop2h 15m

$87

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Mon 3/23

8:00 am-10:11 am

Nonstop2h 11m

Key West

Fri 3/27

11:01 am-1:16 pm

Nonstop2h 15m

$88

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Mon 3/23

8:00 am-10:11 am

Nonstop2h 11m

Key West

Fri 3/27

11:01 am-1:16 pm

Nonstop2h 15m

$90

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Thu 4/23

4:28 pm-5:05 am

1 stop12h 37m

Miami

Sun 4/26

7:00 am-3:33 pm

1 stop8h 33m

$160

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Tue 3/24

6:00 am-8:12 am

Nonstop2h 12m

Miami

Tue 3/31

9:43 pm-11:59 pm

Nonstop2h 16m

$199

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Tue 4/14

7:05 am-12:40 pm

1 stop5h 35m

Miami

Tue 4/21

7:20 am-7:40 pm

2 stops12h 20m

$204

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Tue 4/14

7:05 am-5:30 pm

2 stops10h 25m

Miami

Tue 4/21

7:20 am-7:40 pm

2 stops12h 20m

$209

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Thu 4/9

6:30 am-8:38 am

Nonstop2h 08m

Miami

Tue 4/14

9:45 pm-11:59 pm

Nonstop2h 14m

$215

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Tue 3/24

7:10 am-2:10 pm

1 stop7h 00m

Miami

Tue 3/31

12:01 pm-4:06 pm

1 stop4h 05m

$219

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of July is another great option to travel to Florida Keys, with average flight prices from Knoxville averaging around $362.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Knoxville to Florida Keys is on a Friday when prices can be found for as low as $502. The most expensive day to fly to Florida Keys is Tuesday, with ticket prices averaging around $599.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the afternoon. momondo users have found flights departing from Knoxville to Florida Keys in the afternoon for as low as $404. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $575.

What is the cheapest Knoxville McGhee Tyson to Florida Keys flight route?

Fly from Knoxville McGhee Tyson to Key West for the best Knoxville McGhee Tyson - Florida Keys flight prices

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $404 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Knoxville for as low as $330 on momondo.

What cabin class options are available on Knoxville McGhee Tyson to Florida Keys flights?

There is only 1 cabin class available to choose from on Knoxville McGhee Tyson to Florida Keys flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Florida Keys.

Cheap Knoxville to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Florida Keys

Fastest flight time	2h 08m
Direct flights	Every day
Airports in Florida Keys	3 airports

The fastest flight from Knoxville to Florida Keys takes 2h 08m

Direct flights go from Knoxville to Florida Keys every day.

There are 3 airports in Florida Keys. From Knoxville there are direct flights to Key West (EYW), Miami (MIA).

Search flight deals

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Florida Keys?
Prices for flights from Knoxville McGhee Tyson Airport to Florida Keys refresh daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Florida Keys?
As of February 2026, there are 4 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Florida Keys.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Florida Keys?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The travel and health documents required for your trip to Florida Keys can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florida Keys. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Knoxville to Florida Keys?
Based on momondo bookings for flights between Knoxville and Florida Keys, the leading plane model is Airbus A320-100/200, making up 36.85% of the total bookings. Other popular models include Boeing 737 MAX 8 with 9.59%, Canadair (Bombardier) Regional Jet 900 with 8.40%, and Canadair (Bombardier) Regional Jet 700 with 6.91%.

Best airlines flying from Knoxville to Florida Keys

Compare and see reviews for airlines that fly from Knoxville to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $84	Free Cancellation	Rating 7.2 715 reviews	Search Allegiant Air flights
American Airlines	PriceFrom $250	Free Cancellation	Rating 7.1 11,367 reviews	Search American Airlines flights
Delta	PriceFrom $268	Free Cancellation	Rating 7.9 8,245 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Florida Keys?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Florida Keys for you.

Can I find flights from Knoxville to Florida Keys with flexible booking policies on momondo?

All flight searches from Knoxville to Florida Keys on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Florida Keys?

momondo provides multiple filters to help you find the best flight to Florida Keys from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Florida Keys right now. Can momondo alert me if prices change?

Price alerts on flights to Florida Keys from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.