What is the cheapest airline that flies from Knoxville McGhee Tyson to Florida Keys?

Allegiant Air, Southwest, and Frontier are the most popular carriers operating from Knoxville McGhee Tyson to Florida Keys

What airlines fly to Florida Keys?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to Florida Keys from Knoxville according to our data. Allegiant Air is the first choice among our users, with 74% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

How many flights depart from Knoxville to Florida Keys on average per week?

As of July 2026, there are 16 flights per week flying from Knoxville to Florida Keys. The most common day of the week flights depart is Thu, with 19% of flights taking off on this day.

How many flights depart from Knoxville to Florida Keys on average per day?

As of July 2026, there are 2 flights per day flying from Knoxville to Florida Keys. The most common time of day flights depart is 7:00AM, with 100% of flights taking off at noon.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Florida Keys?

Prices for flights from Knoxville McGhee Tyson Airport to Florida Keys refresh daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Florida Keys?

As of July 2026, there are 4 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Florida Keys.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Florida Keys?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The travel and health documents required for your trip to Florida Keys can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florida Keys. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$46 Cheap Flights from Knoxville to Florida Keys in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:30 am - 9:41 am

TYS

EYW

2h 11mnonstop

10:31 am - 12:46 pm

EYW

TYS

2h 15mnonstop

$65Allegiant Air

Mon, Aug 3 - Fri, Aug 7

7:30 am - 9:41 am

TYS

EYW

2h 11mnonstop

10:31 am - 12:46 pm

EYW

TYS

2h 15mnonstop

$71Allegiant Air

Mon, Aug 3 - Fri, Aug 7

7:30 am - 9:41 am

TYS

EYW

2h 11mnonstop

10:31 am - 12:46 pm

EYW

TYS

2h 15mnonstop

$75Allegiant Air

Mon, Aug 3 - Fri, Aug 7

7:30 am - 9:41 am

TYS

EYW

2h 11mnonstop

10:31 am - 12:46 pm

EYW

TYS

2h 15mnonstop

$77Allegiant Air

Fri, Aug 7 - Fri, Aug 14

7:30 am - 9:41 am

TYS

EYW

2h 11mnonstop

10:31 am - 12:46 pm

EYW

TYS

2h 15mnonstop

$84Allegiant Air

Mon, Aug 3 - Fri, Aug 7

7:30 am - 9:41 am

TYS

EYW

2h 11mnonstop

10:31 am - 12:46 pm

EYW

TYS

2h 15mnonstop

$91Allegiant Air

Fri, Aug 7 - Fri, Aug 14

1:26 pm - 4:22 pm

TYS

MIA

26h 56m

1 stop

5:28 pm - 4:25 pm

MIA

TYS

46h 57m

2 stops

$215Multiple Airlines

Fri, Aug 21 - Fri, Aug 28

8:19 pm - 5:51 am

TYS

MIA

9h 32m

1 stop

6:00 am - 7:24 pm

MIA

TYS

13h 24m

1 stop

$240Frontier

Mon, Aug 10 - Wed, Aug 12

8:19 pm - 5:51 am

TYS

MIA

9h 32m

1 stop

6:00 am - 7:24 pm

MIA

TYS

13h 24m

1 stop

$255Frontier

Mon, Aug 10 - Wed, Aug 12

8:19 pm - 5:51 am

TYS

MIA

9h 32m

1 stop

6:00 am - 7:24 pm

MIA

TYS

13h 24m

1 stop

$257Frontier

Fri, Aug 7 - Mon, Aug 10

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American Airlines flights from Knoxville to Florida Keys

Our best American Airlines deals on Knoxville to Florida Keys flight tickets

American Airlines

Jul 24

TYS6:00 amKnoxville McGhee Tyson

7h 14m

1 stop

EYW1:14 pmKey West

Jul 27

EYW7:33 pmKey West

4h 18m

1 stop

TYS11:51 pmKnoxville McGhee Tyson

$369

American Airlines

Jul 20

TYS11:03 amKnoxville McGhee Tyson

5h 08m

1 stop

EYW4:11 pmKey West

Aug 6

EYW1:41 pmKey West

5h 29m

1 stop

TYS7:10 pmKnoxville McGhee Tyson

$374

American Airlines

Jul 24

TYS6:00 amKnoxville McGhee Tyson

7h 14m

1 stop

EYW1:14 pmKey West

Jul 27

EYW7:33 pmKey West

4h 18m

1 stop

TYS11:51 pmKnoxville McGhee Tyson

$399

Frontier flights from Knoxville to Florida Keys

Our best Frontier deals on Knoxville to Florida Keys flight tickets

Frontier

Aug 10

TYS8:19 pmKnoxville McGhee Tyson

9h 32m

1 stop

MIA5:51 amMiami

Aug 12

MIA6:00 amMiami

13h 24m

1 stop

TYS7:24 pmKnoxville McGhee Tyson

$240

Frontier

Aug 10

TYS8:19 pmKnoxville McGhee Tyson

9h 32m

1 stop

MIA5:51 amMiami

Aug 12

MIA6:00 amMiami

13h 24m

1 stop

TYS7:24 pmKnoxville McGhee Tyson

$255

Frontier

Aug 7

TYS8:19 pmKnoxville McGhee Tyson

9h 32m

1 stop

MIA5:51 amMiami

Aug 10

MIA6:00 amMiami

13h 24m

1 stop

TYS7:24 pmKnoxville McGhee Tyson

$257

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Mon 8/3

7:30 am-9:41 am

Nonstop2h 11m

Key West

Fri 8/7

10:31 am-12:46 pm

Nonstop2h 15m

$65

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Mon 8/3

7:30 am-9:41 am

Nonstop2h 11m

Key West

Fri 8/7

10:31 am-12:46 pm

Nonstop2h 15m

$71

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Mon 8/3

7:30 am-9:41 am

Nonstop2h 11m

Key West

Fri 8/7

10:31 am-12:46 pm

Nonstop2h 15m

$75

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 8/7

7:30 am-9:41 am

Nonstop2h 11m

Key West

Fri 8/14

10:31 am-12:46 pm

Nonstop2h 15m

$77

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Mon 8/3

7:30 am-9:41 am

Nonstop2h 11m

Key West

Fri 8/7

10:31 am-12:46 pm

Nonstop2h 15m

$84

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 8/7

7:30 am-9:41 am

Nonstop2h 11m

Key West

Fri 8/14

10:31 am-12:46 pm

Nonstop2h 15m

$91

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Fri 8/21

1:26 pm-4:22 pm

1 stop26h 56m

Miami

Fri 8/28

5:28 pm-4:25 pm

2 stops46h 57m

$215

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Mon 8/10

8:19 pm-5:51 am

1 stop9h 32m

Miami

Wed 8/12

6:00 am-7:24 pm

1 stop13h 24m

$240

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Mon 8/10

8:19 pm-5:51 am

1 stop9h 32m

Miami

Wed 8/12

6:00 am-7:24 pm

1 stop13h 24m

$255

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Fri 8/7

8:19 pm-5:51 am

1 stop9h 32m

Miami

Mon 8/10

6:00 am-7:24 pm

1 stop13h 24m

$257

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of January is another great option to travel to Florida Keys, with average flight prices from Knoxville averaging around $316.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Knoxville to Florida Keys is on a Friday when prices can be found for as low as $484. The most expensive day to fly to Florida Keys is Monday, with ticket prices averaging around $704.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the afternoon. momondo users have found flights departing from Knoxville to Florida Keys in the afternoon for as low as $397. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $609.

What is the cheapest Knoxville McGhee Tyson to Florida Keys flight route?

Fly from Knoxville McGhee Tyson to Key West for the best Knoxville McGhee Tyson - Florida Keys flight prices

How far in advance should I book a flight from Knoxville to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $410 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Knoxville for as low as $338 on momondo.

What cabin class options are available on Knoxville to Florida Keys flights?

There is only 1 cabin class available to choose from on Knoxville to Florida Keys flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Florida Keys.

Cheap Knoxville to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Florida Keys

Fastest flight time	2h 04m
Direct flights	Every day
Airports in Florida Keys	3 airports

The fastest flight from Knoxville to Florida Keys takes 2h 04m

Direct flights go from Knoxville to Florida Keys every day.

There are 3 airports in Florida Keys. From Knoxville there are direct flights to Key West (EYW), Miami (MIA).

Search flight deals

Frequently asked questions about flying from Knoxville to Florida Keys

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Florida Keys?
Prices for flights from Knoxville McGhee Tyson Airport to Florida Keys refresh daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Florida Keys?
As of July 2026, there are 4 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Florida Keys.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Florida Keys?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The travel and health documents required for your trip to Florida Keys can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florida Keys. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Knoxville to Florida Keys?
Based on momondo bookings for flights between Knoxville and Florida Keys, the leading plane model is Airbus A320-100/200, making up 35.72% of the total bookings. Other popular models include Canadair (Bombardier) Regional Jet 900 with 10.77%, Boeing 737 MAX 8 with 10.28%, and Airbus A319 with 6.98%.

Best airlines flying from Knoxville to Florida Keys

Compare and see reviews for airlines that fly from Knoxville to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $79	Free Cancellation	Rating 7.3 682 reviews	Search Allegiant Air flights
American Airlines	PriceFrom $250	Free Cancellation	Rating 7.1 11,822 reviews	Search American Airlines flights
Delta	PriceFrom $283	Free Cancellation	Rating 7.8 8,474 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Florida Keys?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Florida Keys for you.

Can I find flights from Knoxville to Florida Keys with flexible booking policies on momondo?

All flight searches from Knoxville to Florida Keys on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Florida Keys?

momondo provides multiple filters to help you find the best flight to Florida Keys from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Florida Keys right now. Can momondo alert me if prices change?

Price alerts on flights to Florida Keys from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.