What is the cheapest airline that flies from Knoxville McGhee Tyson to Florida Keys?

Allegiant Air and Southwest are the most popular carriers operating from Knoxville McGhee Tyson to Florida Keys

What airlines fly to Florida Keys?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to Florida Keys from Knoxville according to our data. Allegiant Air is the first choice among our users, with 81% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

How many flights depart from Knoxville to Florida Keys on average per week?

As of September 2026, there are 14 flights per week flying from Knoxville to Florida Keys. The most common day of the week flights depart is Mon, with 14% of flights taking off on this day.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Florida Keys?

Prices for flights from Knoxville McGhee Tyson Airport to Florida Keys refresh daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Florida Keys?

As of September 2026, there are 4 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Florida Keys.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Florida Keys?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The travel and health documents required for your trip to Florida Keys can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florida Keys. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$60 Cheap Flights from Knoxville to Florida Keys in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:00 am - 11:04 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

9:54 am - 12:07 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$76Allegiant Air

Mon, Oct 19 - Fri, Oct 23

9:00 am - 11:04 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

9:54 am - 12:07 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$82Allegiant Air

Mon, Oct 19 - Fri, Oct 23

8:15 am - 10:19 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

10:59 am - 9:44 pmEYW Key West-TYS Knoxville McGhee Tyson

10h 45m1 stop Orlando

$186Multiple Airlines

Mon, Oct 26 - Mon, Nov 2

2:12 pm - 9:24 amTYS Knoxville McGhee Tyson-EYW Key West

43h 12m3 stops Philadelphia Atlanta Hartsfield-Jackson Tampa

11:09 am - 1:22 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$220Multiple Airlines

Mon, Oct 26 - Mon, Nov 2

8:00 am - 8:55 pmTYS Knoxville McGhee Tyson-MIA Miami

12h 55m2 stops Baltimore/Washington Orlando

7:20 am - 5:40 pmMIA Miami-TYS Knoxville McGhee Tyson

10h 20m2 stops Baltimore/Washington Nashville Intl

$303Southwest

Sat, Jan 23 - Sat, Jan 30

7:15 am - 11:25 amTYS Knoxville McGhee Tyson-MIA Miami

4h 10m1 stop Nashville Intl

7:00 am - 4:40 pmMIA Miami-TYS Knoxville McGhee Tyson

9h 40m1 stop Orlando

$308Southwest

Wed, Oct 14 - Wed, Oct 21

6:00 am - 10:55 amTYS Knoxville McGhee Tyson-EYW Key West

4h 55m1 stop Miami

7:57 pm - 12:52 amEYW Key West-TYS Knoxville McGhee Tyson

4h 55m1 stop Miami

$319American Airlines

Mon, Nov 23 - Fri, Nov 27

6:00 am - 9:54 amTYS Knoxville McGhee Tyson-EYW Key West

3h 54m1 stop Miami

5:28 pm - 10:59 pmEYW Key West-TYS Knoxville McGhee Tyson

5h 31m1 stop Miami

$319American Airlines

Tue, Oct 27 - Sat, Oct 31

10:29 am - 5:14 pmTYS Knoxville McGhee Tyson-MIA Miami

6h 45m1 stop Atlanta Hartsfield-Jackson

7:10 am - 1:31 pmMIA Miami-TYS Knoxville McGhee Tyson

6h 21m1 stop Atlanta Hartsfield-Jackson

$421Delta

Wed, Oct 7 - Sat, Oct 17

6:07 pm - 12:57 amTYS Knoxville McGhee Tyson-MIA Miami

6h 50m1 stop Atlanta Hartsfield-Jackson

8:15 am - 1:55 pmMIA Miami-TYS Knoxville McGhee Tyson

5h 40m1 stop Atlanta Hartsfield-Jackson

$421Delta

Wed, Nov 11 - Wed, Nov 18

Cheap last minute flights

Enter your travel dates to find the best prices.

12:30 pm - 7:20 pmTYS Knoxville McGhee Tyson-MIA Miami

6h 50m1 stop Orlando

11:35 am - 5:45 pmMIA Miami-TYS Knoxville McGhee Tyson

6h 10m1 stop Nashville Intl

$421Southwest

Sat, Sep 5 - Sat, Sep 12

12:30 pm - 7:20 pmTYS Knoxville McGhee Tyson-MIA Miami

6h 50m1 stop Orlando

2:20 pm - 7:25 pmMIA Miami-TYS Knoxville McGhee Tyson

5h 05m1 stop Baltimore/Washington

$421Southwest

Sat, Sep 5 - Sat, Sep 12

8:55 am - 3:50 pmTYS Knoxville McGhee Tyson-MIA Miami

6h 55m1 stop Baltimore/Washington

12:50 pm - 8:00 pmMIA Miami-TYS Knoxville McGhee Tyson

7h 10m1 stop Baltimore/Washington

$421Southwest

Sun, Sep 6 - Fri, Sep 11

7:40 pm - 9:59 pmTYS Knoxville McGhee Tyson-MIA Miami

2h 19mnonstop

4:30 pm - 6:44 pmMIA Miami-TYS Knoxville McGhee Tyson

2h 14mnonstop

$429American Airlines

Sat, Sep 5 - Sat, Sep 12

7:40 pm - 9:59 pmTYS Knoxville McGhee Tyson-MIA Miami

2h 19mnonstop

4:30 pm - 6:44 pmMIA Miami-TYS Knoxville McGhee Tyson

2h 14mnonstop

$429American Airlines

Sat, Sep 5 - Sat, Sep 12

8:00 am - 11:27 amTYS Knoxville McGhee Tyson-EYW Key West

27h 27m1 stop Orlando Sanford Intl

3:48 pm - 10:44 amEYW Key West-TYS Knoxville McGhee Tyson

18h 56m1 stop Tampa St. Petersburg

$431Multiple Airlines

Thu, Sep 3 - Sat, Sep 5

11:34 am - 4:19 pmTYS Knoxville McGhee Tyson-EYW Key West

4h 45m1 stop Tampa St. Petersburg

3:48 pm - 10:44 amEYW Key West-TYS Knoxville McGhee Tyson

18h 56m1 stop Tampa St. Petersburg

$447Allegiant Air

Thu, Sep 3 - Sat, Sep 5

7:00 am - 4:52 amTYS Knoxville McGhee Tyson-MIA Miami

21h 52m1 stop Denver Intl

8:50 pm - 7:34 pmMIA Miami-TYS Knoxville McGhee Tyson

22h 44m1 stop Philadelphia

$452Multiple Airlines

Sun, Sep 6 - Sun, Sep 13

5:00 pm - 10:00 pmTYS Knoxville McGhee Tyson-MIA Miami

5h 00m1 stop Atlanta Hartsfield-Jackson

8:25 am - 2:40 pmMIA Miami-TYS Knoxville McGhee Tyson

6h 15m1 stop Atlanta Hartsfield-Jackson

$534Delta

Sat, Sep 5 - Fri, Sep 11

8:35 am - 1:00 pmTYS Knoxville McGhee Tyson-MIA Miami

4h 25m1 stop Atlanta Hartsfield-Jackson

6:03 pm - 11:52 pmMIA Miami-TYS Knoxville McGhee Tyson

5h 49m1 stop Atlanta Hartsfield-Jackson

$1,037Delta

Wed, Sep 2 - Wed, Sep 2

Cheap direct flights

Enter your travel dates to find the best prices.

9:00 am - 11:04 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

9:54 am - 12:07 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$76Allegiant Air

Mon, Oct 19 - Fri, Oct 23

9:00 am - 11:04 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

9:54 am - 12:07 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$82Allegiant Air

Mon, Oct 19 - Fri, Oct 23

9:00 am - 11:04 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

9:54 am - 12:07 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$86Allegiant Air

Mon, Oct 19 - Fri, Oct 23

8:15 am - 10:19 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

11:09 am - 1:22 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$90Allegiant Air

Mon, Oct 26 - Mon, Nov 2

9:00 am - 11:04 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

9:54 am - 12:07 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$92Allegiant Air

Mon, Oct 19 - Fri, Oct 30

7:00 am - 9:04 amTYS Knoxville McGhee Tyson-EYW Key West

2h 04mnonstop

11:09 am - 1:22 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 13mnonstop

$113Allegiant Air

Fri, Oct 30 - Mon, Nov 2

11:00 am - 1:12 pmTYS Knoxville McGhee Tyson-EYW Key West

2h 12mnonstop

2:02 pm - 4:19 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 17mnonstop

$226Allegiant Air

Fri, Dec 4 - Fri, Dec 11

2:34 pm - 4:46 pmTYS Knoxville McGhee Tyson-EYW Key West

2h 12mnonstop

5:36 pm - 7:53 pmEYW Key West-TYS Knoxville McGhee Tyson

2h 17mnonstop

$234Allegiant Air

Fri, Feb 5 - Mon, Feb 8

6:00 am - 8:16 amTYS Knoxville McGhee Tyson-MIA Miami

2h 16mnonstop

8:50 pm - 10:59 pmMIA Miami-TYS Knoxville McGhee Tyson

2h 09mnonstop

$399American Airlines

Wed, Oct 14 - Wed, Oct 21

6:00 am - 8:16 amTYS Knoxville McGhee Tyson-MIA Miami

2h 16mnonstop

10:54 am - 1:09 pmMIA Miami-TYS Knoxville McGhee Tyson

2h 15mnonstop

$401American Airlines

Sat, Oct 17 - Sat, Oct 24

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Southwest flights from Knoxville to Florida Keys

Our best Southwest deals on Knoxville to Florida Keys flight tickets

Southwest

Oct 14

TYS7:15 amKnoxville McGhee Tyson

4h 10m

1 stop

MIA11:25 amMiami

Oct 21

MIA7:00 amMiami

9h 40m

1 stop

TYS4:40 pmKnoxville McGhee Tyson

$308

Southwest

Oct 24

TYS2:55 pmKnoxville McGhee Tyson

7h 15m

2 stops

MIA10:10 pmMiami

Oct 31

MIA6:25 amMiami

9h 05m

2 stops

TYS3:30 pmKnoxville McGhee Tyson

$313

Southwest

Oct 14

TYS7:15 amKnoxville McGhee Tyson

10h 15m

2 stops

MIA5:30 pmMiami

Oct 21

MIA7:00 amMiami

9h 40m

1 stop

TYS4:40 pmKnoxville McGhee Tyson

$314

American Airlines flights from Knoxville to Florida Keys

Our best American Airlines deals on Knoxville to Florida Keys flight tickets

American Airlines

Sep 9

TYS7:00 amKnoxville McGhee Tyson

2h 15m

MIA9:15 amMiami

Sep 12

MIA4:30 pmMiami

2h 14m

TYS6:44 pmKnoxville McGhee Tyson

$401

American Airlines

Sep 9

TYS8:18 amKnoxville McGhee Tyson

7h 16m

1 stop

MIA3:34 pmMiami

Sep 12

MIA8:54 pmMiami

2h 13m

TYS11:07 pmKnoxville McGhee Tyson

$411

American Airlines

Sep 5

TYS7:40 pmKnoxville McGhee Tyson

2h 19m

MIA9:59 pmMiami

Sep 12

MIA4:30 pmMiami

2h 14m

TYS6:44 pmKnoxville McGhee Tyson

$429

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Mon 10/19

9:00 am-11:04 am

Nonstop2h 04m

Key West

Fri 10/23

9:54 am-12:07 pm

Nonstop2h 13m

$76

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Mon 10/19

9:00 am-11:04 am

Nonstop2h 04m

Key West

Fri 10/23

9:54 am-12:07 pm

Nonstop2h 13m

$82

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Mon 10/26

8:15 am-10:19 am

Nonstop2h 04m

Key West

Mon 11/2

10:59 am-9:44 pm

1 stop10h 45m

$186

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Mon 10/26

2:12 pm-9:24 am

3 stops43h 12m

Key West

Mon 11/2

11:09 am-1:22 pm

Nonstop2h 13m

$220

KnoxvilleMiami

TYS Knoxville McGhee Tyson - MIA Miami

TYSMIA

Knoxville McGhee Tyson

Sat 1/23

8:00 am-8:55 pm

2 stops12h 55m

Miami

Sat 1/30

7:20 am-5:40 pm

2 stops10h 20m

$303

KnoxvilleMiami

TYS Knoxville McGhee Tyson - MIA Miami

TYSMIA

Knoxville McGhee Tyson

Wed 10/14

7:15 am-11:25 am

1 stop4h 10m

Miami

Wed 10/21

7:00 am-4:40 pm

1 stop9h 40m

$308

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Mon 11/23

6:00 am-10:55 am

1 stop4h 55m

Key West

Fri 11/27

7:57 pm-12:52 am

1 stop4h 55m

$319

KnoxvilleKey West

TYS Knoxville McGhee Tyson - EYW Key West

TYSEYW

Knoxville McGhee Tyson

Tue 10/27

6:00 am-9:54 am

1 stop3h 54m

Key West

Sat 10/31

5:28 pm-10:59 pm

1 stop5h 31m

$319

KnoxvilleMiami

TYS Knoxville McGhee Tyson - MIA Miami

TYSMIA

Knoxville McGhee Tyson

Wed 10/7

10:29 am-5:14 pm

1 stop6h 45m

Miami

Sat 10/17

7:10 am-1:31 pm

1 stop6h 21m

$421

KnoxvilleMiami

TYS Knoxville McGhee Tyson - MIA Miami

TYSMIA

Knoxville McGhee Tyson

Wed 11/11

6:07 pm-12:57 am

1 stop6h 50m

Miami

Wed 11/18

8:15 am-1:55 pm

1 stop5h 40m

$421

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of February is another great option to travel to Florida Keys, with average flight prices from Knoxville averaging around $297.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Knoxville to Florida Keys is on a Friday when prices can be found for as low as $516. The most expensive day to fly to Florida Keys is Monday, with ticket prices averaging around $719.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the afternoon. momondo users have found flights departing from Knoxville to Florida Keys in the afternoon for as low as $397. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $626.

What is the cheapest Knoxville McGhee Tyson to Florida Keys flight route?

Fly from Knoxville McGhee Tyson to Key West for the best Knoxville McGhee Tyson - Florida Keys flight prices

How far in advance should I book a flight from Knoxville to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $415 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Knoxville for as low as $322 on momondo.

What cabin class options are available on Knoxville to Florida Keys flights?

There is only 1 cabin class available to choose from on Knoxville to Florida Keys flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Florida Keys.

Cheap Knoxville to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Florida Keys

Best Price Found	$60
Fastest flight time	2h 04m
Direct flights	Every day
Airports in Florida Keys	3 airports

The best one-way flight to Florida Keys from Knoxville in the past 72 hours is $60. The best round-trip flight deal from Knoxville to Florida Keys found on momondo in the last 72 hours is $76.

The fastest flight from Knoxville to Florida Keys takes 2h 04m

Direct flights go from Knoxville to Florida Keys every day.

There are 3 airports in Florida Keys. From Knoxville there are direct flights to Key West (EYW), Miami (MIA).

Search flight deals

Frequently asked questions about flying from Knoxville to Florida Keys

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Florida Keys?
Prices for flights from Knoxville McGhee Tyson Airport to Florida Keys refresh daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Florida Keys?
As of September 2026, there are 4 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Florida Keys.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Florida Keys?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The travel and health documents required for your trip to Florida Keys can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florida Keys. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Knoxville to Florida Keys?
Based on momondo bookings for flights between Knoxville and Florida Keys, the leading plane model is Airbus A320-100/200, making up 34.79% of the total bookings. Other popular models include Boeing 737 MAX 8 with 12.93%, Canadair (Bombardier) Regional Jet 900 with 9.95%, and Canadair (Bombardier) Regional Jet 700 with 6.87%.

Best airlines flying from Knoxville to Florida Keys

Compare and see reviews for airlines that fly from Knoxville to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $71	Free Cancellation	Rating 7.3 676 reviews		Search Allegiant Air flights
American Airlines	PriceFrom $250	Free Cancellation	Rating 7.1 12,026 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Florida Keys?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Florida Keys for you.

Can I find flights from Knoxville to Florida Keys with flexible booking policies on momondo?

All flight searches from Knoxville to Florida Keys on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Florida Keys?

momondo provides multiple filters to help you find the best flight to Florida Keys from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Florida Keys right now. Can momondo alert me if prices change?

Price alerts on flights to Florida Keys from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.