Cheap flights from Knoxville to Denver from $46

The cheapest month to fly to Denver from Knoxville is in November. Flight prices, which tend to average around $247, are often lower during this time because this is during the off-season. If you don’t want to visit Denver in November, then you should wait until September to fly from Knoxville, when ticket prices are also cheap, with an average price of $259.

The cheapest day to depart on your flight to Denver is on a Sunday when prices can be found for as low as $324. This is often the case because there is less demand to fly during this day of the week. The most expensive day to fly to Denver is Wednesday, with ticket prices averaging around $454.

The cheapest time of day to fly to Denver is at noon when flights can be purchased for as low as $217. Flights in the morning are often more expensive with an average ticket price of $449.

Fly from Knoxville McGhee Tyson to Denver Intl for the best Knoxville McGhee Tyson - Denver Intl flight prices

You are more likely to see cheaper flights to Denver from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Denver for around $303 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Denver from Knoxville for as low as $239 on momondo.

There are 4 cabin classes available to choose from on Knoxville to Denver flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

United Airlines and Southwest are the most popular carriers operating from Knoxville McGhee Tyson to Denver Intl

United Airlines, Allegiant Air and American Airlines are the top three most popular airlines that fly to Denver from Knoxville according to our data. United Airlines is the first choice among our users, with 41% of people opting to fly with this airline when traveling to Denver. Keep in mind that there are 6 different airlines that fly to Denver on a routine basis, so you have a few additional options to choose from.

As of August 2026, 2 flights take off from Knoxville and land in Denver each day. The most common flight departure time for this route is 4:00PM, with 57% of daily flights taking off in the afternoon.

As of August 2026, there are 17 flights per week flying from Knoxville to Denver. The most common day of the week flights depart is Wed, with 24% of flights taking off on this day.