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Cheap flights from Islip, New York to Louisville from $327

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Islip, New York to Louisville departing on 3/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Islip, New York to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
5:55 pm - 12:40 am
ISP
-
SDF
6h 45m
1 stop
Southwest Logo
6:10 am - 4:30 pm
SDF
-
ISP
10h 20m
1 stop
$327Southwest
Mon, Mar 23 - Fri, Mar 27
Southwest Logo
2:00 pm - 10:40 pm
ISP
-
SDF
8h 40m
2 stops
Southwest Logo
6:10 am - 4:30 pm
SDF
-
ISP
10h 20m
1 stop
$333Southwest
Mon, Mar 23 - Fri, Mar 27
Southwest Logo
2:00 pm - 10:40 pm
ISP
-
SDF
8h 40m
2 stops
Southwest Logo
4:30 pm - 11:55 pm
SDF
-
ISP
7h 25m
2 stops
$345Southwest
Mon, Mar 23 - Fri, Mar 27
Southwest Logo
6:00 am - 12:55 pm
ISP
-
SDF
6h 55m
1 stop
Southwest Logo
6:20 am - 11:55 am
SDF
-
ISP
5h 35m
1 stop
$365Southwest
Sat, May 23 - Tue, May 26
Southwest Logo
6:00 am - 3:50 pm
ISP
-
SDF
9h 50m
2 stops
Southwest Logo
6:20 am - 11:55 am
SDF
-
ISP
5h 35m
1 stop
$378Southwest
Sat, May 23 - Tue, May 26
Southwest Logo
6:00 am - 3:50 pm
ISP
-
SDF
9h 50m
2 stops
Southwest Logo
3:30 pm - 10:10 pm
SDF
-
ISP
6h 40m
2 stops
$414Southwest
Sat, May 23 - Tue, May 26

Southwest flights from Islip, New York to Louisville

Our best Southwest deals on Islip, New York to Louisville flight tickets
Southwest
Mar 23
ISP5:55 pmIslip Long Island
6h 45m
1 stop
SDF12:40 amLouisville Intl
Mar 27
SDF6:10 amLouisville Intl
10h 20m
1 stop
ISP4:30 pmIslip Long Island
$327
Southwest
Mar 23
ISP2:00 pmIslip Long Island
8h 40m
2 stops
SDF10:40 pmLouisville Intl
Mar 27
SDF6:10 amLouisville Intl
10h 20m
1 stop
ISP4:30 pmIslip Long Island
$333
Southwest
Mar 23
ISP2:00 pmIslip Long Island
8h 40m
2 stops
SDF10:40 pmLouisville Intl
Mar 27
SDF4:30 pmLouisville Intl
7h 25m
2 stops
ISP11:55 pmIslip Long Island
$345

momondo Fare Finder

 
Customize your flight search to find flights from Islip, New York to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Islip, New York to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Mon 3/23

5:55 pm-12:40 am

1 stop6h 45m

Louisville Intl

Fri 3/27

6:10 am-4:30 pm

1 stop10h 20m

$327

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Mon 3/23

2:00 pm-10:40 pm

2 stops8h 40m

Louisville Intl

Fri 3/27

6:10 am-4:30 pm

1 stop10h 20m

$333

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Mon 3/23

2:00 pm-10:40 pm

2 stops8h 40m

Louisville Intl

Fri 3/27

4:30 pm-11:55 pm

2 stops7h 25m

$345

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Sat 5/23

6:00 am-12:55 pm

1 stop6h 55m

Louisville Intl

Tue 5/26

6:20 am-11:55 am

1 stop5h 35m

$365

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Sat 5/23

6:00 am-3:50 pm

2 stops9h 50m

Louisville Intl

Tue 5/26

6:20 am-11:55 am

1 stop5h 35m

$378

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Sat 5/23

6:00 am-3:50 pm

2 stops9h 50m

Louisville Intl

Tue 5/26

3:30 pm-10:10 pm

2 stops6h 40m

$414

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Louisville from

How to get the cheapest flight ticket from Islip, New York to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Louisville?

On average, the least expensive day to fly to Louisville from Islip, New York is on a Saturday. momondo users have found tickets for Saturday departures for as low as $305. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from Islip, New York to Louisville on a Sunday will generally be more expensive and average around $382. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Louisville?

Our data shows that the cheapest Islip, New York to Louisville flights are usually those with departure times in the afternoon. Our users have found flights to Louisville in the afternoon for as low as $323. At noon is when there is more demand to fly to Louisville, so prices are often more expensive at around $407 per ticket.

When to book flights from Islip, New York to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from Islip, New York to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Islip, New York to Louisville (ISP to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Islip, New York to Louisville

Fastest flight time

6h 55m

Direct flights

None
The fastest flight from Islip, New York to Louisville takes 6h 55m
There are no direct flights from Islip, New York to Louisville. There are no popular flight routes from Islip, New York to Louisville.
Search flight deals

  • How far is Islip Long Island to Louisville Intl by plane?

    The straight-line distance from Islip Long Island to Louisville Intl is 689.3 mi. Flights usually cover this in 6h 55m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Islip Long Island Airport to Louisville Intl Airport?

    Prices for flights from Islip Long Island Airport to Louisville Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Islip Long Island Airport to Louisville Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Islip Long Island Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The required travel and health documents for your Louisville Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Louisville Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
West Baden Springs
Bardstown
Jeffersonville
Shepherdsville
New Albany
Corydon
Elizabeth
Brandenburg
Charlestown
Springfield
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Islip to Louisville?

It is quick and easy to find Islip to Louisville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Louisville that suits you.

Can I find flights from Islip to Louisville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Louisville from Islip with this policy.

How can momondo help me find flights from Islip to Louisville?

Once you have performed a search for Islip to Louisville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Islip to Louisville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Islip to Louisville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Louisville and let you know when they change.

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