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Cheap flights from Islip, New York to Louisville from $251

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Islip, New York to Louisville departing on 4/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Islip, New York to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
4:30 pm - 11:45 pm
ISP
-
SDF
7h 15m
1 stop
Southwest Logo
5:45 am - 4:30 pm
SDF
-
ISP
10h 45m
1 stop
$280Southwest
Thu, Apr 23 - Mon, Apr 27
Southwest Logo
6:00 am - 3:00 pm
ISP
-
SDF
9h 00m
2 stops
Southwest Logo
5:45 am - 4:30 pm
SDF
-
ISP
10h 45m
1 stop
$333Southwest
Thu, Apr 23 - Mon, Apr 27
Southwest Logo
4:30 pm - 11:45 pm
ISP
-
SDF
7h 15m
1 stop
Southwest Logo
5:50 am - 11:50 am
SDF
-
ISP
6h 00m
1 stop
$338Southwest
Thu, Apr 23 - Sun, Apr 26
Southwest Logo
4:30 pm - 11:45 pm
ISP
-
SDF
7h 15m
1 stop
Southwest Logo
3:50 pm - 11:50 pm
SDF
-
ISP
8h 00m
2 stops
$351Southwest
Thu, Apr 23 - Sun, Apr 26
Southwest Logo
4:30 pm - 11:45 pm
ISP
-
SDF
7h 15m
1 stop
Southwest Logo
4:45 pm - 8:25 pm
SDF
-
ISP
3h 40mnonstop
$356Southwest
Thu, May 21 - Mon, May 25
Southwest Logo
4:30 pm - 11:45 pm
ISP
-
SDF
7h 15m
1 stop
Southwest Logo
4:45 pm - 11:30 pm
SDF
-
ISP
6h 45m
1 stop
$373Southwest
Thu, May 21 - Mon, May 25
Southwest Logo
6:00 am - 12:25 pm
ISP
-
SDF
6h 25m
1 stop
Southwest Logo
10:45 am - 5:15 pm
SDF
-
ISP
6h 30m
1 stop
$383Southwest
Tue, Jul 14 - Thu, Jul 16
Southwest Logo
6:00 am - 3:00 pm
ISP
-
SDF
9h 00m
2 stops
Southwest Logo
2:40 pm - 11:30 pm
SDF
-
ISP
8h 50m
2 stops
$385Southwest
Thu, Apr 23 - Mon, Apr 27
Southwest Logo
2:55 pm - 10:30 pm
ISP
-
SDF
7h 35m
2 stops
Southwest Logo
5:30 pm - 11:40 pm
SDF
-
ISP
6h 10m
1 stop
$388Southwest
Tue, Jul 14 - Thu, Jul 16
Southwest Logo
6:00 am - 3:00 pm
ISP
-
SDF
9h 00m
2 stops
Southwest Logo
3:50 pm - 11:50 pm
SDF
-
ISP
8h 00m
2 stops
$403Southwest
Thu, Apr 23 - Sun, Apr 26

Southwest flights from Islip, New York to Louisville

Our best Southwest deals on Islip, New York to Louisville flight tickets
Southwest
Apr 23
ISP4:30 pmIslip Long Island
7h 15m
1 stop
SDF11:45 pmLouisville Intl
Apr 27
SDF5:45 amLouisville Intl
10h 45m
1 stop
ISP4:30 pmIslip Long Island
$280
Southwest
Apr 23
ISP6:00 amIslip Long Island
9h 00m
2 stops
SDF3:00 pmLouisville Intl
Apr 27
SDF5:45 amLouisville Intl
10h 45m
1 stop
ISP4:30 pmIslip Long Island
$333
Southwest
Apr 23
ISP4:30 pmIslip Long Island
7h 15m
1 stop
SDF11:45 pmLouisville Intl
Apr 26
SDF5:50 amLouisville Intl
6h 00m
1 stop
ISP11:50 amIslip Long Island
$338

Breeze Airways flights from Islip, New York to Louisville

Our best Breeze Airways deals on Islip, New York to Louisville flight tickets
Breeze Airways
Sep 4
ISP2:28 pmIslip Long Island
18h 08m
1 stop
SDF8:36 amLouisville Intl
Sep 7
SDF8:28 pmLouisville Intl
14h 48m
2 stops
ISP11:16 amIslip Long Island
$580
Breeze Airways
Sep 24
ISP7:45 pmIslip Long Island
12h 17m
2 stops
SDF8:02 amLouisville Intl
Sep 28
SDF9:22 pmLouisville Intl
13h 58m
2 stops
ISP11:20 amIslip Long Island
$635
Breeze Airways
Sep 23
ISP12:00 pmIslip Long Island
44h 02m
3 stops
SDF8:02 amLouisville Intl
Sep 28
SDF9:22 pmLouisville Intl
13h 58m
2 stops
ISP11:20 amIslip Long Island
$716

momondo Fare Finder

 
Customize your flight search to find flights from Islip, New York to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 31, 2026.
Use the filters below to find and compare flights from Islip, New York to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Thu 4/23

4:30 pm-11:45 pm

1 stop7h 15m

Louisville Intl

Mon 4/27

5:45 am-4:30 pm

1 stop10h 45m

$280

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Thu 4/23

6:00 am-3:00 pm

2 stops9h 00m

Louisville Intl

Mon 4/27

5:45 am-4:30 pm

1 stop10h 45m

$333

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Thu 4/23

4:30 pm-11:45 pm

1 stop7h 15m

Louisville Intl

Sun 4/26

5:50 am-11:50 am

1 stop6h 00m

$338

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Thu 4/23

4:30 pm-11:45 pm

1 stop7h 15m

Louisville Intl

Sun 4/26

3:50 pm-11:50 pm

2 stops8h 00m

$351
Quickest round-trip

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Thu 5/21

4:30 pm-11:45 pm

1 stop7h 15m

Louisville Intl

Mon 5/25

4:45 pm-8:25 pm

Nonstop3h 40m

$356

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Thu 5/21

4:30 pm-11:45 pm

1 stop7h 15m

Louisville Intl

Mon 5/25

4:45 pm-11:30 pm

1 stop6h 45m

$373

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Tue 7/14

6:00 am-12:25 pm

1 stop6h 25m

Louisville Intl

Thu 7/16

10:45 am-5:15 pm

1 stop6h 30m

$383

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Thu 4/23

6:00 am-3:00 pm

2 stops9h 00m

Louisville Intl

Mon 4/27

2:40 pm-11:30 pm

2 stops8h 50m

$385

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Tue 7/14

2:55 pm-10:30 pm

2 stops7h 35m

Louisville Intl

Thu 7/16

5:30 pm-11:40 pm

1 stop6h 10m

$388

IslipLouisville

ISP - SDF

ISPSDF

Islip Long Island

Thu 4/23

6:00 am-3:00 pm

2 stops9h 00m

Louisville Intl

Sun 4/26

3:50 pm-11:50 pm

2 stops8h 00m

$403

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Louisville from

How to get the cheapest flight ticket from Islip, New York to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Louisville?

On average, the least expensive day to fly to Louisville from Islip, New York is on a Saturday. momondo users have found tickets for Saturday departures for as low as $310. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from Islip, New York to Louisville on a Sunday will generally be more expensive and average around $454. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Louisville?

Our data shows that the cheapest Islip, New York to Louisville flights are usually those with departure times in the evening. Our users have found flights to Louisville in the evening for as low as $336. At noon is when there is more demand to fly to Louisville, so prices are often more expensive at around $401 per ticket.

When to book flights from Islip, New York to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from Islip, New York to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Islip, New York to Louisville (ISP to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Islip, New York to Louisville

Fastest flight time

6h 10m

Direct flights

None
The fastest flight from Islip, New York to Louisville takes 6h 10m
There are no direct flights from Islip, New York to Louisville. There are no popular flight routes from Islip, New York to Louisville.
Search flight deals

  • How far is Islip Long Island to Louisville Intl by plane?

    The straight-line distance from Islip Long Island to Louisville Intl is 689.3 mi. Flights usually cover this in 6h 10m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Islip Long Island Airport to Louisville Intl Airport?

    Prices for flights from Islip Long Island Airport to Louisville Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Islip Long Island Airport to Louisville Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Islip Long Island Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The required travel and health documents for your Louisville Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Louisville Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
West Baden Springs
Bardstown
Jeffersonville
New Albany
Shepherdsville
Corydon
Brandenburg
Elizabeth
Charlestown
Springfield
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Islip to Louisville?

It is quick and easy to find Islip to Louisville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Louisville that suits you.

Can I find flights from Islip to Louisville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Louisville from Islip with this policy.

How can momondo help me find flights from Islip to Louisville?

Once you have performed a search for Islip to Louisville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Islip to Louisville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Islip to Louisville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Louisville and let you know when they change.

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