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Cheap flights from Islip, New York to Santo Domingo from $176

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Islip, New York to Santo Domingo departing on 9/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Islip, New York to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
6:00 am - 3:16 pm
ISP
-
SDQ
9h 16m
1 stop
JetBlue Logo
1:32 pm - 9:35 pm
SDQ
-
ISP
8h 03m
1 stop
$376JetBlue
Sun, Sep 27 - Thu, Oct 1
JetBlue Logo
6:00 am - 3:16 pm
ISP
-
SDQ
9h 16m
1 stop
JetBlue Logo
1:32 pm - 9:35 pm
SDQ
-
ISP
8h 03m
1 stop
$502JetBlue
Sat, Oct 3 - Sat, Oct 10
JetBlue Logo
6:00 am - 3:21 pm
ISP
-
SDQ
9h 21m
1 stop
JetBlue Logo
1:34 pm - 11:27 pm
SDQ
-
ISP
9h 53m
1 stop
$522JetBlue
Thu, Aug 20 - Sun, Aug 23
JetBlue Logo
6:00 am - 3:21 pm
ISP
-
SDQ
9h 21m
1 stop
JetBlue Logo
1:34 pm - 9:34 pm
SDQ
-
ISP
8h 00m
1 stop
$571JetBlue
Thu, Aug 20 - Mon, Aug 24
JetBlue Logo
4:58 pm - 1:10 pm
ISP
-
SDQ
20h 12m
1 stop
JetBlue Logo
1:35 pm - 9:44 pm
SDQ
-
ISP
8h 09m
1 stop
$626JetBlue
Tue, Jul 7 - Tue, Jul 14
Frontier Logo
3:34 pm - 11:03 am
ISP
-
SDQ
19h 29m
2 stops
Frontier Logo
12:18 pm - 9:53 am
SDQ
-
ISP
21h 35m
2 stops
$628Frontier
Sat, Aug 8 - Thu, Aug 13
JetBlue Logo
4:58 pm - 11:59 pm
ISP
-
SDQ
7h 01m
1 stop
JetBlue Logo
1:34 pm - 9:34 pm
SDQ
-
ISP
8h 00m
1 stop
$648JetBlue
Thu, Jul 16 - Wed, Aug 19
JetBlue Logo
4:58 pm - 11:59 pm
ISP
-
SDQ
7h 01m
1 stop
JetBlue Logo
1:34 pm - 9:34 pm
SDQ
-
ISP
8h 00m
1 stop
$657JetBlue
Sun, Jul 19 - Wed, Aug 19
JetBlue Logo
5:00 pm - 11:59 pm
ISP
-
SDQ
6h 59m
1 stop
JetBlue Logo
5:01 am - 10:56 pm
SDQ
-
ISP
17h 55m
1 stop
$665JetBlue
Tue, Jul 14 - Tue, Jul 21
JetBlue Logo
6:00 am - 3:23 pm
ISP
-
SDQ
9h 23m
1 stop
JetBlue Logo
1:34 pm - 10:56 pm
SDQ
-
ISP
9h 22m
1 stop
$668JetBlue
Sat, Jul 18 - Tue, Aug 18

Frontier flights from Islip, New York to Santo Domingo

Our best Frontier deals on Islip, New York to Santo Domingo flight tickets
Frontier
Aug 8
ISP3:34 pmIslip Long Island
19h 29m
2 stops
SDQ11:03 amSanto Domingo Las Americas
Aug 13
SDQ12:18 pmSanto Domingo Las Americas
21h 35m
2 stops
ISP9:53 amIslip Long Island
$628
Frontier
Jul 14
ISP3:34 pmIslip Long Island
19h 29m
2 stops
SDQ11:03 amSanto Domingo Las Americas
Jul 21
SDQ12:18 pmSanto Domingo Las Americas
21h 40m
2 stops
ISP9:58 amIslip Long Island
$707
Frontier
Jul 7
ISP3:34 pmIslip Long Island
19h 29m
2 stops
SDQ11:03 amSanto Domingo Las Americas
Jul 14
SDQ12:18 pmSanto Domingo Las Americas
21h 35m
2 stops
ISP9:53 amIslip Long Island
$709

JetBlue flights from Islip, New York to Santo Domingo

Our best JetBlue deals on Islip, New York to Santo Domingo flight tickets
JetBlue
Sep 27
ISP6:00 amIslip Long Island
9h 16m
1 stop
SDQ3:16 pmSanto Domingo Las Americas
Oct 1
SDQ1:32 pmSanto Domingo Las Americas
8h 03m
1 stop
ISP9:35 pmIslip Long Island
$376
JetBlue
Oct 3
ISP6:00 amIslip Long Island
9h 16m
1 stop
SDQ3:16 pmSanto Domingo Las Americas
Oct 10
SDQ1:32 pmSanto Domingo Las Americas
8h 03m
1 stop
ISP9:35 pmIslip Long Island
$502
JetBlue
Aug 20
ISP6:00 amIslip Long Island
9h 21m
1 stop
SDQ3:21 pmSanto Domingo Las Americas
Aug 23
SDQ1:34 pmSanto Domingo Las Americas
9h 53m
1 stop
ISP11:27 pmIslip Long Island
$522

momondo Fare Finder

 
Customize your flight search to find flights from Islip, New York to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 24, 2026.
Use the filters below to find and compare flights from Islip, New York to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Sun 9/27

6:00 am-3:16 pm

1 stop9h 16m

Santo Domingo Las Americas

Thu 10/1

1:32 pm-9:35 pm

1 stop8h 03m

$376

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Sat 10/3

6:00 am-3:16 pm

1 stop9h 16m

Santo Domingo Las Americas

Sat 10/10

1:32 pm-9:35 pm

1 stop8h 03m

$502

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Thu 8/20

6:00 am-3:21 pm

1 stop9h 21m

Santo Domingo Las Americas

Sun 8/23

1:34 pm-11:27 pm

1 stop9h 53m

$522

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Thu 8/20

6:00 am-3:21 pm

1 stop9h 21m

Santo Domingo Las Americas

Mon 8/24

1:34 pm-9:34 pm

1 stop8h 00m

$571

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Tue 7/7

4:58 pm-1:10 pm

1 stop20h 12m

Santo Domingo Las Americas

Tue 7/14

1:35 pm-9:44 pm

1 stop8h 09m

$626

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Sat 8/8

3:34 pm-11:03 am

2 stops19h 29m

Santo Domingo Las Americas

Thu 8/13

12:18 pm-9:53 am

2 stops21h 35m

$628
Quickest round-trip

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Thu 7/16

4:58 pm-11:59 pm

1 stop7h 01m

Santo Domingo Las Americas

Wed 8/19

1:34 pm-9:34 pm

1 stop8h 00m

$648

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Sun 7/19

4:58 pm-11:59 pm

1 stop7h 01m

Santo Domingo Las Americas

Wed 8/19

1:34 pm-9:34 pm

1 stop8h 00m

$657

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Tue 7/14

5:00 pm-11:59 pm

1 stop6h 59m

Santo Domingo Las Americas

Tue 7/21

5:01 am-10:56 pm

1 stop17h 55m

$665

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Sat 7/18

6:00 am-3:23 pm

1 stop9h 23m

Santo Domingo Las Americas

Tue 8/18

1:34 pm-10:56 pm

1 stop9h 22m

$668

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Islip, New York to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Monday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $456. The most expensive day to fly to Santo Domingo is Saturday, with ticket prices averaging around $485.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the evening when flights can be purchased for as low as $455. Try not to purchase tickets in the afternoon because they tend to be around $508. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Islip, New York to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Islip, New York to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Islip, New York to Santo Domingo (ISP to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Islip, New York to Santo Domingo

Fastest flight time

6h 22m

Direct flights

None
The fastest flight from Islip, New York to Santo Domingo takes 6h 22m
There are no direct flights from Islip, New York to Santo Domingo. There are no popular flight routes from Islip, New York to Santo Domingo.
Search flight deals

Frequently asked questions about flying from Islip, New York to Santo Domingo

  • How far is Islip Long Island to Santo Domingo Las Americas by plane?

    There are 1548.2 mi between Islip Long Island and Santo Domingo Las Americas. In terms of flight time, this usually takes a little over 6h 22m.

  • When did momondo last update prices for flights from Islip Long Island Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Islip Long Island Airport to Santo Domingo Las Americas Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Islip Long Island Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Islip Long Island Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Islip to Santo Domingo?

It is quick and easy to find Islip to Santo Domingo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santo Domingo that suits you.

Can I find flights from Islip to Santo Domingo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Islip to Santo Domingo flights to just show those with flexible booking policies.

How can momondo help me find flights from Islip to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from Islip.

I’m not ready to book a flight from Islip to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Islip to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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