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Cheap flights from Islip, New York to Santo Domingo from $124

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Islip, New York to Santo Domingo departing on 4/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Islip, New York to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
5:25 pm - 7:32 am
ISP
-
SDQ
14h 07m
1 stop
JetBlue Logo
8:45 am - 5:44 pm
SDQ
-
ISP
8h 59m
1 stop
$529JetBlue
Wed, Apr 29 - Wed, May 20
JetBlue Logo
6:40 pm - 7:32 am
ISP
-
SDQ
12h 52m
1 stop
JetBlue Logo
8:45 am - 5:44 pm
SDQ
-
ISP
8h 59m
1 stop
$540JetBlue
Wed, May 13 - Wed, May 20
Frontier Logo
6:43 pm - 11:05 am
ISP
-
SDQ
16h 22m
2 stops
Frontier Logo
12:10 pm - 10:05 am
SDQ
-
ISP
21h 55m
2 stops
$548Frontier
Wed, May 27 - Sat, May 30
Frontier Logo
3:35 pm - 11:05 am
ISP
-
SDQ
19h 30m
2 stops
Frontier Logo
12:10 pm - 10:05 am
SDQ
-
ISP
21h 55m
2 stops
$586Frontier
Thu, May 14 - Thu, May 21
JetBlue Logo
5:15 pm - 7:31 am
ISP
-
SDQ
14h 16m
1 stop
JetBlue Logo
8:43 am - 4:18 pm
SDQ
-
ISP
7h 35m
1 stop
$598JetBlue
Fri, Apr 17 - Tue, Apr 21
JetBlue Logo
8:59 pm - 12:28 pm
ISP
-
SDQ
15h 29m
1 stop
JetBlue Logo
9:20 am - 11:35 am
SDQ
-
ISP
26h 15m
1 stop
$606JetBlue
Thu, May 14 - Thu, May 21
JetBlue Logo
7:00 am - 6:31 pm
ISP
-
SDQ
11h 31m
1 stop
JetBlue Logo
8:43 am - 4:18 pm
SDQ
-
ISP
7h 35m
1 stop
$610JetBlue
Sun, Apr 12 - Thu, Apr 16
JetBlue Logo
6:40 pm - 7:32 am
ISP
-
SDQ
12h 52m
1 stop
JetBlue Logo
8:45 am - 5:44 pm
SDQ
-
ISP
8h 59m
1 stop
$619JetBlue
Fri, May 8 - Tue, May 12
JetBlue Logo
6:40 pm - 7:32 am
ISP
-
SDQ
12h 52m
1 stop
JetBlue Logo
8:45 am - 5:44 pm
SDQ
-
ISP
8h 59m
1 stop
$638JetBlue
Sat, May 9 - Wed, May 13
JetBlue Logo
6:40 pm - 7:32 am
ISP
-
SDQ
12h 52m
1 stop
JetBlue Logo
8:45 am - 5:44 pm
SDQ
-
ISP
8h 59m
1 stop
$661JetBlue
Thu, May 7 - Tue, May 12

JetBlue flights from Islip, New York to Santo Domingo

Our best JetBlue deals on Islip, New York to Santo Domingo flight tickets
JetBlue
Apr 29
ISP5:25 pmIslip Long Island
14h 07m
1 stop
SDQ7:32 amSanto Domingo Las Americas
May 20
SDQ8:45 amSanto Domingo Las Americas
8h 59m
1 stop
ISP5:44 pmIslip Long Island
$529
JetBlue
May 13
ISP6:40 pmIslip Long Island
12h 52m
1 stop
SDQ7:32 amSanto Domingo Las Americas
May 20
SDQ8:45 amSanto Domingo Las Americas
8h 59m
1 stop
ISP5:44 pmIslip Long Island
$540
JetBlue
Apr 17
ISP5:15 pmIslip Long Island
14h 16m
1 stop
SDQ7:31 amSanto Domingo Las Americas
Apr 21
SDQ8:43 amSanto Domingo Las Americas
7h 35m
1 stop
ISP4:18 pmIslip Long Island
$598

Frontier flights from Islip, New York to Santo Domingo

Our best Frontier deals on Islip, New York to Santo Domingo flight tickets
Frontier
Apr 9
ISP8:36 pmIslip Long Island
13h 31m
1 stop
SDQ10:07 amSanto Domingo Las Americas
Apr 12
SDQ9:20 pmSanto Domingo Las Americas
17h 51m
2 stops
ISP3:11 pmIslip Long Island
$485
Frontier
Apr 3
ISP6:40 pmIslip Long Island
19h 50m
1 stop
SDQ2:30 pmSanto Domingo Las Americas
Apr 10
SDQ11:12 amSanto Domingo Las Americas
23h 18m
1 stop
ISP10:30 amIslip Long Island
$529
Frontier
May 27
ISP6:43 pmIslip Long Island
16h 22m
2 stops
SDQ11:05 amSanto Domingo Las Americas
May 30
SDQ12:10 pmSanto Domingo Las Americas
21h 55m
2 stops
ISP10:05 amIslip Long Island
$548

momondo Fare Finder

 
Customize your flight search to find flights from Islip, New York to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 31, 2026.
Use the filters below to find and compare flights from Islip, New York to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Wed 4/29

5:25 pm-7:32 am

1 stop14h 07m

Santo Domingo Las Americas

Wed 5/20

8:45 am-5:44 pm

1 stop8h 59m

$529

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Wed 5/13

6:40 pm-7:32 am

1 stop12h 52m

Santo Domingo Las Americas

Wed 5/20

8:45 am-5:44 pm

1 stop8h 59m

$540

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Wed 5/27

6:43 pm-11:05 am

2 stops16h 22m

Santo Domingo Las Americas

Sat 5/30

12:10 pm-10:05 am

2 stops21h 55m

$548

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Thu 5/14

3:35 pm-11:05 am

2 stops19h 30m

Santo Domingo Las Americas

Thu 5/21

12:10 pm-10:05 am

2 stops21h 55m

$586

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Fri 4/17

5:15 pm-7:31 am

1 stop14h 16m

Santo Domingo Las Americas

Tue 4/21

8:43 am-4:18 pm

1 stop7h 35m

$598

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Thu 5/14

8:59 pm-12:28 pm

1 stop15h 29m

Santo Domingo Las Americas

Thu 5/21

9:20 am-11:35 am

1 stop26h 15m

$606
Quickest round-trip

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Sun 4/12

7:00 am-6:31 pm

1 stop11h 31m

Santo Domingo Las Americas

Thu 4/16

8:43 am-4:18 pm

1 stop7h 35m

$610

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Fri 5/8

6:40 pm-7:32 am

1 stop12h 52m

Santo Domingo Las Americas

Tue 5/12

8:45 am-5:44 pm

1 stop8h 59m

$619

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Sat 5/9

6:40 pm-7:32 am

1 stop12h 52m

Santo Domingo Las Americas

Wed 5/13

8:45 am-5:44 pm

1 stop8h 59m

$638

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Thu 5/7

6:40 pm-7:32 am

1 stop12h 52m

Santo Domingo Las Americas

Tue 5/12

8:45 am-5:44 pm

1 stop8h 59m

$661

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Islip, New York to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Monday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $445. The most expensive day to fly to Santo Domingo is Saturday, with ticket prices averaging around $475.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the morning when flights can be purchased for as low as $454. Try not to purchase tickets in the afternoon because they tend to be around $500. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Islip, New York to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Islip, New York to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Islip, New York to Santo Domingo (ISP to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Islip, New York to Santo Domingo

Fastest flight time

9h 15m

Direct flights

None
The fastest flight from Islip, New York to Santo Domingo takes 9h 15m
There are no direct flights from Islip, New York to Santo Domingo. There are no popular flight routes from Islip, New York to Santo Domingo.
Search flight deals

  • How far is Islip Long Island to Santo Domingo Las Americas by plane?

    There are 1548.2 mi between Islip Long Island and Santo Domingo Las Americas. In terms of flight time, this usually takes a little over 9h 15m.

  • When did momondo last update prices for flights from Islip Long Island Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Islip Long Island Airport to Santo Domingo Las Americas Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Islip Long Island Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Islip Long Island Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Islip to Santo Domingo?

It is quick and easy to find Islip to Santo Domingo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santo Domingo that suits you.

Can I find flights from Islip to Santo Domingo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Islip to Santo Domingo flights to just show those with flexible booking policies.

How can momondo help me find flights from Islip to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from Islip.

I’m not ready to book a flight from Islip to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Islip to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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