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Cheap flights from Islip, New York to Santo Domingo from $136

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Islip, New York to Santo Domingo departing on 2/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Islip, New York to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
9:45 am - 6:08 pm
ISP
-
SDQ
8h 23m
1 stop
JetBlue Logo
7:33 pm - 8:55 am
SDQ
-
ISP
13h 22m
1 stop
$437JetBlue
Sat, Mar 21 - Wed, Mar 25
JetBlue Logo
9:45 am - 6:23 pm
ISP
-
SDQ
8h 38m
1 stop
JetBlue Logo
7:33 pm - 8:55 am
SDQ
-
ISP
13h 22m
1 stop
$518JetBlue
Thu, Mar 12 - Mon, Mar 16
JetBlue Logo
5:15 pm - 7:32 am
ISP
-
SDQ
14h 17m
1 stop
JetBlue Logo
8:43 am - 4:30 pm
SDQ
-
ISP
7h 47m
1 stop
$560JetBlue
Thu, Apr 23 - Mon, Apr 27
JetBlue Logo
9:45 am - 5:39 pm
ISP
-
SDQ
7h 54m
1 stop
JetBlue Logo
8:43 am - 4:19 pm
SDQ
-
ISP
7h 36m
1 stop
$594JetBlue
Wed, Mar 25 - Mon, Apr 20
JetBlue Logo
5:15 pm - 7:32 am
ISP
-
SDQ
14h 17m
1 stop
JetBlue Logo
8:43 am - 4:30 pm
SDQ
-
ISP
7h 47m
1 stop
$625JetBlue
Thu, Apr 23 - Mon, Apr 27
JetBlue Logo
8:25 am - 5:40 pm
ISP
-
SDQ
9h 15m
1 stop
JetBlue Logo
10:20 am - 10:35 pm
SDQ
-
ISP
12h 15m
1 stop
$652JetBlue
Sun, Mar 29 - Fri, Apr 3
JetBlue Logo
9:45 am - 6:09 pm
ISP
-
SDQ
8h 24m
1 stop
JetBlue Logo
7:33 pm - 8:55 am
SDQ
-
ISP
13h 22m
1 stop
$656JetBlue
Sat, Mar 14 - Wed, Mar 18
Multiple Airlines Logo
9:59 am - 2:40 am
ISP
-
SDQ
16h 41m
1 stop
Multiple Airlines Logo
2:52 am - 11:10 am
SDQ
-
ISP
32h 18m
2 stops
$684Multiple Airlines
Thu, Apr 2 - Mon, Apr 13
JetBlue Logo
5:15 pm - 7:32 am
ISP
-
SDQ
14h 17m
1 stop
JetBlue Logo
8:43 am - 4:19 pm
SDQ
-
ISP
7h 36m
1 stop
$692JetBlue
Mon, Apr 20 - Fri, Apr 24
JetBlue Logo
9:45 am - 5:39 pm
ISP
-
SDQ
7h 54m
1 stop
JetBlue Logo
10:20 am - 10:35 pm
SDQ
-
ISP
12h 15m
1 stop
$783JetBlue
Wed, Mar 25 - Wed, Apr 1

Frontier flights from Islip, New York to Santo Domingo

Our best Frontier deals on Islip, New York to Santo Domingo flight tickets
Frontier
Feb 11
ISP2:03 pmIslip Long Island
20h 23m
1 stop
SDQ11:26 amSanto Domingo Las Americas
Feb 15
SDQ10:46 amSanto Domingo Las Americas
21h 52m
1 stop
ISP7:38 amIslip Long Island
$574
Frontier
Feb 16
ISP8:23 amIslip Long Island
26h 33m
1 stop
SDQ11:56 amSanto Domingo Las Americas
Feb 24
SDQ1:11 pmSanto Domingo Las Americas
20h 29m
1 stop
ISP8:40 amIslip Long Island
$639
Frontier
Feb 16
ISP8:23 amIslip Long Island
26h 33m
1 stop
SDQ11:56 amSanto Domingo Las Americas
Feb 24
SDQ1:11 pmSanto Domingo Las Americas
20h 29m
1 stop
ISP8:40 amIslip Long Island
$668

JetBlue flights from Islip, New York to Santo Domingo

Our best JetBlue deals on Islip, New York to Santo Domingo flight tickets
JetBlue
Mar 21
ISP9:45 amIslip Long Island
8h 23m
1 stop
SDQ6:08 pmSanto Domingo Las Americas
Mar 25
SDQ7:33 pmSanto Domingo Las Americas
13h 22m
1 stop
ISP8:55 amIslip Long Island
$437
JetBlue
Mar 12
ISP9:45 amIslip Long Island
8h 38m
1 stop
SDQ6:23 pmSanto Domingo Las Americas
Mar 16
SDQ7:33 pmSanto Domingo Las Americas
13h 22m
1 stop
ISP8:55 amIslip Long Island
$518
JetBlue
Apr 23
ISP5:15 pmIslip Long Island
14h 17m
1 stop
SDQ7:32 amSanto Domingo Las Americas
Apr 27
SDQ8:43 amSanto Domingo Las Americas
7h 47m
1 stop
ISP4:30 pmIslip Long Island
$560

momondo Fare Finder

 
Customize your flight search to find flights from Islip, New York to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 10, 2026.
Use the filters below to find and compare flights from Islip, New York to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Sat 3/21

9:45 am-6:08 pm

1 stop8h 23m

Santo Domingo Las Americas

Wed 3/25

7:33 pm-8:55 am

1 stop13h 22m

$437

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Thu 3/12

9:45 am-6:23 pm

1 stop8h 38m

Santo Domingo Las Americas

Mon 3/16

7:33 pm-8:55 am

1 stop13h 22m

$518

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Thu 4/23

5:15 pm-7:32 am

1 stop14h 17m

Santo Domingo Las Americas

Mon 4/27

8:43 am-4:30 pm

1 stop7h 47m

$560

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Wed 3/25

9:45 am-5:39 pm

1 stop7h 54m

Santo Domingo Las Americas

Mon 4/20

8:43 am-4:19 pm

1 stop7h 36m

$594

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Thu 4/23

5:15 pm-7:32 am

1 stop14h 17m

Santo Domingo Las Americas

Mon 4/27

8:43 am-4:30 pm

1 stop7h 47m

$625

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Sun 3/29

8:25 am-5:40 pm

1 stop9h 15m

Santo Domingo Las Americas

Fri 4/3

10:20 am-10:35 pm

1 stop12h 15m

$652

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Sat 3/14

9:45 am-6:09 pm

1 stop8h 24m

Santo Domingo Las Americas

Wed 3/18

7:33 pm-8:55 am

1 stop13h 22m

$656

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Thu 4/2

9:59 am-2:40 am

1 stop16h 41m

Santo Domingo Las Americas

Mon 4/13

2:52 am-11:10 am

2 stops32h 18m

$684

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Mon 4/20

5:15 pm-7:32 am

1 stop14h 17m

Santo Domingo Las Americas

Fri 4/24

8:43 am-4:19 pm

1 stop7h 36m

$692

IslipSanto Domingo

ISP - SDQ

ISPSDQ

Islip Long Island

Wed 3/25

9:45 am-5:39 pm

1 stop7h 54m

Santo Domingo Las Americas

Wed 4/1

10:20 am-10:35 pm

1 stop12h 15m

$783

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Islip, New York to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Monday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $448. The most expensive day to fly to Santo Domingo is Saturday, with ticket prices averaging around $472.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is at noon when flights can be purchased for as low as $445. Try not to purchase tickets in the afternoon because they tend to be around $496. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Islip, New York to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Islip, New York to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Islip, New York to Santo Domingo (ISP to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Islip, New York to Santo Domingo

Fastest flight time

8h 23m

Direct flights

None
The fastest flight from Islip, New York to Santo Domingo takes 8h 23m
There are no direct flights from Islip, New York to Santo Domingo. There are no popular flight routes from Islip, New York to Santo Domingo.
Search flight deals

  • How far is Islip Long Island to Santo Domingo Las Americas by plane?

    There are 1548.2 mi between Islip Long Island and Santo Domingo Las Americas. In terms of flight time, this usually takes a little over 8h 23m.

  • When did momondo last update prices for flights from Islip Long Island Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Islip Long Island Airport to Santo Domingo Las Americas Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Islip Long Island Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Islip Long Island Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Islip to Santo Domingo?

It is quick and easy to find Islip to Santo Domingo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santo Domingo that suits you.

Can I find flights from Islip to Santo Domingo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Islip to Santo Domingo flights to just show those with flexible booking policies.

How can momondo help me find flights from Islip to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from Islip.

I’m not ready to book a flight from Islip to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Islip to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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