Cheap flights from Iowa to Panama City from $119

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Panama City departing on 8/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Delta Logo
5:12 pm - 11:03 pmDSM-ECP
5h 51m1 stop
Delta Logo
6:00 am - 10:40 amECP-DSM
4h 40m1 stop
$237Delta
Find Deal
Sat, Sep 13 - Sat, Sep 20
Delta Logo
6:10 pm - 11:03 pmOMA-ECP
4h 53m1 stop
Delta Logo
4:46 pm - 9:17 pmECP-OMA
4h 31m1 stop
$237Delta
Find Deal
Wed, Sep 17 - Wed, Sep 24
Delta Logo
5:12 pm - 11:06 pmDSM-ECP
5h 54m1 stop
Delta Logo
7:10 am - 1:27 pmECP-DSM
6h 17m1 stop
$239Delta
Find Deal
Wed, Sep 3 - Wed, Sep 10
Delta Logo
6:37 pm - 11:10 pmOMA-ECP
4h 33m1 stop
Delta Logo
5:32 pm - 11:59 pmECP-OMA
6h 27m1 stop
$239Delta
Find Deal
Tue, Oct 7 - Tue, Oct 14
Southwest Logo
1:45 pm - 6:50 pmOMA-ECP
5h 05m1 stop
Southwest Logo
6:35 am - 3:25 pmECP-OMA
8h 50m1 stop
$244Southwest
Find Deal
Tue, Sep 9 - Mon, Sep 15
American Airlines Logo
11:38 am - 10:53 pmOMA-ECP
11h 15m2 stops
American Airlines Logo
3:41 pm - 11:59 pmECP-OMA
8h 18m2 stops
$249American Airlines
Find Deal
Tue, Oct 7 - Wed, Oct 15
Southwest Logo
5:25 am - 1:55 pmDSM-ECP
8h 30m2 stops
Southwest Logo
1:30 pm - 11:35 pmECP-DSM
10h 05m2 stops
$251Southwest
Find Deal
Sat, Dec 13 - Thu, Dec 18
American Airlines Logo
6:46 am - 5:30 pmOMA-ECP
10h 44m2 stops
American Airlines Logo
5:25 pm - 11:01 pmECP-OMA
5h 36m1 stop
$257American Airlines
Find Deal
Wed, Aug 27 - Fri, Aug 29
United Airlines Logo
8:00 am - 1:03 pmOMA-ECP
5h 03m1 stop
United Airlines Logo
6:30 am - 4:18 pmECP-OMA
9h 48m2 stops
$312United Airlines
Find Deal
Mon, Sep 1 - Sat, Sep 6
United Airlines Logo
8:00 am - 1:03 pmOMA-ECP
5h 03m1 stop
United Airlines Logo
6:30 am - 4:18 pmECP-OMA
9h 48m2 stops
$314United Airlines
Find Deal
Mon, Sep 1 - Sat, Sep 6

Delta flights from Iowa to Panama City, Florida

Our best Delta deals on Iowa to Panama City, Florida flight tickets
Delta
Sep 13
DSM5:12 pmDes Moines
5h 51m
1 stop
ECP11:03 pmPanama City NW Florida Beaches
Sep 20
ECP6:00 amPanama City NW Florida Beaches
4h 40m
1 stop
DSM10:40 amDes Moines
Delta
Sep 3
DSM5:12 pmDes Moines
5h 54m
1 stop
ECP11:06 pmPanama City NW Florida Beaches
Sep 10
ECP7:10 amPanama City NW Florida Beaches
6h 17m
1 stop
DSM1:27 pmDes Moines
Delta
Sep 13
DSM2:49 pmDes Moines
8h 14m
2 stops
ECP11:03 pmPanama City NW Florida Beaches
Sep 20
ECP5:02 pmPanama City NW Florida Beaches
5h 35m
1 stop
DSM10:37 pmDes Moines

Southwest flights from Iowa to Panama City, Florida

Our best Southwest deals on Iowa to Panama City, Florida flight tickets
Southwest
Sep 9
OMA1:45 pmOmaha Eppley Airfield
5h 05m
1 stop
ECP6:50 pmPanama City NW Florida Beaches
Sep 15
ECP6:35 amPanama City NW Florida Beaches
8h 50m
1 stop
OMA3:25 pmOmaha Eppley Airfield
Southwest
Dec 13
DSM5:25 amDes Moines
8h 30m
2 stops
ECP1:55 pmPanama City NW Florida Beaches
Dec 18
ECP1:30 pmPanama City NW Florida Beaches
10h 05m
2 stops
DSM11:35 pmDes Moines
Southwest
Sep 9
OMA6:10 amOmaha Eppley Airfield
6h 20m
2 stops
ECP12:30 pmPanama City NW Florida Beaches
Sep 15
ECP6:35 amPanama City NW Florida Beaches
8h 50m
1 stop
OMA3:25 pmOmaha Eppley Airfield

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 5, 2025.
Use the filters below to find and compare flights from Iowa to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPanama City

DSM - ECP

DSMECP

Des Moines

Sat 9/13

5:12 pm-11:03 pm

1 stop5h 51m

Panama City NW Florida Beaches

Sat 9/20

6:00 am-10:40 am

1 stop4h 40m

$237

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Wed 9/17

6:10 pm-11:03 pm

1 stop4h 53m

Panama City NW Florida Beaches

Wed 9/24

4:46 pm-9:17 pm

1 stop4h 31m

$237

Des MoinesPanama City

DSM - ECP

DSMECP

Des Moines

Wed 9/3

5:12 pm-11:06 pm

1 stop5h 54m

Panama City NW Florida Beaches

Wed 9/10

7:10 am-1:27 pm

1 stop6h 17m

$239

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Tue 10/7

6:37 pm-11:10 pm

1 stop4h 33m

Panama City NW Florida Beaches

Tue 10/14

5:32 pm-11:59 pm

1 stop6h 27m

$239

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Tue 9/9

1:45 pm-6:50 pm

1 stop5h 05m

Panama City NW Florida Beaches

Mon 9/15

6:35 am-3:25 pm

1 stop8h 50m

$244

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Tue 10/7

11:38 am-10:53 pm

2 stops11h 15m

Panama City NW Florida Beaches

Wed 10/15

3:41 pm-11:59 pm

2 stops8h 18m

$249

Des MoinesPanama City

DSM - ECP

DSMECP

Des Moines

Sat 12/13

5:25 am-1:55 pm

2 stops8h 30m

Panama City NW Florida Beaches

Thu 12/18

1:30 pm-11:35 pm

2 stops10h 05m

$251

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Wed 8/27

6:46 am-5:30 pm

2 stops10h 44m

Panama City NW Florida Beaches

Fri 8/29

5:25 pm-11:01 pm

1 stop5h 36m

$257

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Mon 9/1

8:00 am-1:03 pm

1 stop5h 03m

Panama City NW Florida Beaches

Sat 9/6

6:30 am-4:18 pm

2 stops9h 48m

$312

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Mon 9/1

8:00 am-1:03 pm

1 stop5h 03m

Panama City NW Florida Beaches

Sat 9/6

6:30 am-4:18 pm

2 stops9h 48m

$314

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Iowa to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Iowa is in September. Flight prices, which tend to average around $316, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Panama City, Florida, with average flight prices from Iowa averaging around $348.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $358. On the other hand, Sunday is the most expensive day to depart from Iowa because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $466.

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Iowa when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $438 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Iowa for as low as $305 on momondo.

Can stopping save me money on Iowa to Panama City, Florida flights?

You could potentially save up to 6% on your flight if you consider stops on a Iowa to Panama City, Florida flight.

Cheap Iowa to Panama City, Florida flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Panama City, Florida

Best Price Found

$119

Fastest flight time

3h 58m

Direct flights

None

Airports in Panama City, Florida

1 airport
The best one-way flight to Panama City, Florida from Iowa in the past 72 hours is $119. The best round-trip flight deal from Iowa to Panama City, Florida found on momondo in the last 72 hours is $237.
The fastest flight from Iowa to Panama City, Florida takes 3h 58m
There are no direct flights from Iowa to Panama City, Florida. Popular non-direct routes for this connection are Des Moines Airport - Panama City NW Florida Beaches Airport, Omaha Eppley Airfield Airport - Panama City NW Florida Beaches Airport and Cedar Rapids Airport - Panama City NW Florida Beaches Airport.
There is 1 airport near Panama City, Florida: Panama City NW Florida Beaches (ECP)

  • When did momondo last update prices for flights from Iowa to Panama City NW Florida Beaches Airport?

    Prices for flights from Iowa to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Iowa to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Iowa to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Iowa to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents you'll need for your trip to Panama City NW Florida Beaches Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.


Best airlines flying from Iowa to Panama City, Florida

Compare and see reviews for airlines that fly from Iowa to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $248Free CancellationRating
8.0
7,985 reviews
Search Delta flights
United AirlinesPriceFrom $253Free CancellationRating
7.4
8,916 reviews
Search United Airlines flights
SouthwestPriceFrom $351Free CancellationRating
8.0
4,246 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Iowa.

Can I find flights from Iowa to Panama City with flexible booking policies on momondo?

All flight searches from Iowa to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Iowa to Panama City?

Once all potential Iowa to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Iowa to Panama City right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Iowa to Panama City flights. All you need is a valid email address and we will do the rest; it is that quick and easy.


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1 adult
Sun 8/10
Sun 8/17

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