What airlines fly to Greenville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Greenville from Iowa according to our data. American Airlines is the first choice among our users, with 79% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 3 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

How long does it take to fly to Greenville?

Flight times from Iowa to Greenville vary, but if you’re flying out of Cedar Rapids and flying into Charlotte (one of the most popular routes), then the duration is 2h 11m on average. Another popular route from Iowa to Greenville is flying from Des Moines to Charlotte, which will take roughly 2h 18m. Keep in mind that layovers or delays could extend your travel time.

What is the cheapest airline that flies from Iowa to Greenville?

American Airlines, Delta, and Allegiant Air are the most popular carriers operating from Iowa to Greenville

When did momondo last update prices for flights from Iowa to Greenville Airport?

Prices for flights from Iowa to Greenville Airport were last updated today.

How many operators does momondo search for flights from Iowa to Greenville Airport?

There are 4 operators available for flights from Iowa to Greenville Airport as of August 2025.

How old do you have to be to fly from Iowa to Greenville Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Greenville Airport.

What documentation or ID do you need to fly to Greenville Airport?

The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$105 Cheap Flights from Iowa to Greenville in 2025

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Find the cheapest flights from Iowa to Greenville

Round-trip

One-way

Last minute

Cheap round-trip flights

3:50 pm - 10:00 pmDSM-GSP

5h 10m1 stop

7:44 pm - 11:45 pmGSP-DSM

5h 01m1 stop

$209American Airlines

Find Deal

Tue, Sep 9 - Tue, Sep 16

4:09 pm - 10:27 pmDSM-GSP

5h 18m1 stop

6:33 pm - 11:13 pmGSP-DSM

5h 40m1 stop

$210American Airlines

Find Deal

Tue, Sep 23 - Tue, Sep 30

3:25 pm - 10:46 pmDSM-GSP

6h 21m1 stop

9:35 am - 2:23 pmGSP-DSM

5h 48m1 stop

$237United Airlines

Find Deal

Sat, Sep 13 - Sat, Sep 27

3:25 pm - 10:46 pmDSM-GSP

6h 21m1 stop

6:05 am - 2:23 pmGSP-DSM

9h 18m2 stops

$242United Airlines

Find Deal

Sat, Sep 13 - Sat, Sep 27

3:45 pm - 5:35 pmDSM-GSP

24h 50m1 stop

9:24 pm - 6:00 pmGSP-DSM

21h 36m1 stop

$246Allegiant Air

Find Deal

Sun, Aug 24 - Thu, Aug 28

4:13 pm - 11:34 pmCID-GSP

6h 21m2 stops

5:30 am - 11:30 amGSP-CID

7h 00m2 stops

$259Delta

Find Deal

Tue, Sep 9 - Tue, Sep 16

5:57 am - 11:24 amCID-GSP

4h 27m1 stop

6:13 pm - 10:43 pmGSP-CID

5h 30m1 stop

$271Delta

Find Deal

Tue, Sep 16 - Wed, Sep 17

10:13 am - 1:57 pmCID-GSP

26h 44m1 stop

11:18 am - 10:46 amGSP-CID

24h 28m1 stop

$291Allegiant Air

Find Deal

Thu, Sep 25 - Sun, Sep 28

6:30 am - 7:26 pmDSM-GSP

11h 56m2 stops

9:24 pm - 6:00 pmGSP-DSM

21h 36m1 stop

$300

Find Deal

Sun, Aug 24 - Thu, Aug 28

8:30 am - 8:48 amDSM-GSP

23h 18m3 stops

10:34 am - 9:56 amGSP-DSM

24h 22m2 stops

$571

Find Deal

Sun, Aug 24 - Thu, Aug 28

American Airlines flights from Iowa to Greenville

Our best American Airlines deals on Iowa to Greenville flight tickets

American Airlines

Sep 9

DSM3:50 pmDes Moines

5h 10m

1 stop

GSP10:00 pmGreenville

Sep 16

GSP7:44 pmGreenville

5h 01m

1 stop

DSM11:45 pmDes Moines

$209

Find similar

American Airlines

Sep 23

DSM4:09 pmDes Moines

5h 18m

1 stop

GSP10:27 pmGreenville

Sep 30

GSP6:33 pmGreenville

5h 40m

1 stop

DSM11:13 pmDes Moines

$210

Find similar

American Airlines

Sep 9

DSM1:40 pmDes Moines

8h 18m

2 stops

GSP10:58 pmGreenville

Sep 16

GSP6:33 pmGreenville

5h 40m

1 stop

DSM11:13 pmDes Moines

$214

Find similar

United Airlines flights from Iowa to Greenville

Our best United Airlines deals on Iowa to Greenville flight tickets

United Airlines

Sep 13

DSM3:25 pmDes Moines

6h 21m

1 stop

GSP10:46 pmGreenville

Sep 27

GSP9:35 amGreenville

5h 48m

1 stop

DSM2:23 pmDes Moines

$237

Find similar

United Airlines

Sep 13

DSM3:25 pmDes Moines

6h 21m

1 stop

GSP10:46 pmGreenville

Sep 27

GSP6:05 amGreenville

9h 18m

2 stops

DSM2:23 pmDes Moines

$242

Find similar

United Airlines

Sep 13

DSM8:00 amDes Moines

8h 05m

2 stops

GSP5:05 pmGreenville

Sep 27

GSP6:05 amGreenville

9h 18m

2 stops

DSM2:23 pmDes Moines

$262

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Tue 9/9

3:50 pm-10:00 pm

1 stop5h 10m

Greenville

Tue 9/16

7:44 pm-11:45 pm

1 stop5h 01m

$209

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Tue 9/23

4:09 pm-10:27 pm

1 stop5h 18m

Greenville

Tue 9/30

6:33 pm-11:13 pm

1 stop5h 40m

$210

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Sat 9/13

3:25 pm-10:46 pm

1 stop6h 21m

Greenville

Sat 9/27

9:35 am-2:23 pm

1 stop5h 48m

$237

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Sat 9/13

3:25 pm-10:46 pm

1 stop6h 21m

Greenville

Sat 9/27

6:05 am-2:23 pm

2 stops9h 18m

$242

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Sun 8/24

3:45 pm-5:35 pm

1 stop24h 50m

Greenville

Thu 8/28

9:24 pm-6:00 pm

1 stop21h 36m

$246

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Tue 9/9

4:13 pm-11:34 pm

2 stops6h 21m

Greenville

Tue 9/16

5:30 am-11:30 am

2 stops7h 00m

$259

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Tue 9/16

5:57 am-11:24 am

1 stop4h 27m

Greenville

Wed 9/17

6:13 pm-10:43 pm

1 stop5h 30m

$271

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Thu 9/25

10:13 am-1:57 pm

1 stop26h 44m

Greenville

Sun 9/28

11:18 am-10:46 am

1 stop24h 28m

$291

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Sun 8/24

6:30 am-7:26 pm

2 stops11h 56m

Greenville

Thu 8/28

9:24 pm-6:00 pm

1 stop21h 36m

$300

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Sun 8/24

8:30 am-8:48 am

3 stops23h 18m

Greenville

Thu 8/28

10:34 am-9:56 am

2 stops24h 22m

$571

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Iowa to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Greenville?

The month of January is another great option to travel to Greenville, with average flight prices from Iowa averaging around $333.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Friday is the cheapest day to fly to Greenville from Iowa. The lowest ticket price found for a Friday departure recently was $349. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $608. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the afternoon. Flights from Iowa to Greenville during this time can be as low as $373. Flights to Greenville are more costly in the morning, with an average ticket price of $437. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Cheap Iowa to Greenville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Greenville

Best Price Found	$105
Fastest flight time	3h 55m
Direct flights	None
Airports in Greenville	1 airport

The best one-way flight to Greenville from Iowa in the past 72 hours is $105. The best round-trip flight deal from Iowa to Greenville found on momondo in the last 72 hours is $209.

The fastest flight from Iowa to Greenville takes 3h 55m

There are no direct flights from Iowa to Greenville. Popular non-direct routes for this connection are Des Moines Airport - Greenville Airport, Omaha Eppley Airfield Airport - Greenville Airport and Cedar Rapids Airport - Greenville Airport.

There is 1 airport near Greenville: Greenville (GSP)

Search flight deals

When did momondo last update prices for flights from Iowa to Greenville Airport?
Prices for flights from Iowa to Greenville Airport were last updated today.
How many operators does momondo search for flights from Iowa to Greenville Airport?
There are 4 operators available for flights from Iowa to Greenville Airport as of August 2025.
How old do you have to be to fly from Iowa to Greenville Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Greenville Airport.
What documentation or ID do you need to fly to Greenville Airport?
The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Iowa to Greenville

Compare and see reviews for airlines that fly from Iowa to Greenville with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $232	Free Cancellation	Rating 8.0 7,979 reviews	Search Delta flights
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
United Airlines	PriceFrom $271	Free Cancellation	Rating 7.4 8,920 reviews	Search United Airlines flights

Anderson

Simpsonville

Greenwood

Seneca

Greer

Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from Iowa.

Can I find flights from Iowa to Greenville with flexible booking policies on momondo?

All flight searches from Iowa to Greenville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Iowa to Greenville?

momondo provides multiple filters to help you find the best flight to Greenville from Iowa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Iowa to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Iowa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.