How long does it take to fly to Greenville?

Flight times from Iowa to Greenville vary, but if you’re flying out of Des Moines and flying into Charlotte (one of the most popular routes), then the duration is 2h 14m on average. Another popular route from Iowa to Greenville is flying from Cedar Rapids to Charlotte, which will take roughly 2h 23m. Keep in mind that layovers or delays could extend your travel time.

What airlines fly to Greenville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Greenville from Iowa according to our data. American Airlines is the first choice among our users, with 74% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 4 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Iowa to Greenville?

Allegiant Air, Delta, and Southwest are the most popular carriers operating from Iowa to Greenville

When did momondo last update prices for flights from Iowa to Greenville Airport?

Prices for flights from Iowa to Greenville Airport were last updated today.

How many operators does momondo search for flights from Iowa to Greenville Airport?

There are 3 operators available for flights from Iowa to Greenville Airport as of November 2026.

How old do you have to be to fly from Iowa to Greenville Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Greenville Airport.

What documentation or ID do you need to fly to Greenville Airport?

The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$148 Cheap Flights from Iowa to Greenville in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Iowa to Greenville

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

10:57 am - 4:51 pmDSM Des Moines-GSP Greenville

4h 54m1 stop Charlotte Douglas

7:10 am - 2:48 pmGSP Greenville-DSM Des Moines

8h 38m1 stop Dallas/Fort Worth

$325American Airlines

Thu, Jan 21 - Sat, Jan 23

8:07 am - 1:15 pmDSM Des Moines-GSP Greenville

4h 08m1 stop Charlotte Douglas

5:21 pm - 11:03 pmGSP Greenville-DSM Des Moines

6h 42m1 stop Charlotte Douglas

$325American Airlines

Sat, Jan 23 - Sat, Jan 23

12:52 pm - 11:34 pmDSM Des Moines-GSP Greenville

9h 42m2 stops Chicago O'Hare Intl Newark

6:30 am - 12:17 pmGSP Greenville-DSM Des Moines

6h 47m1 stop Chicago O'Hare Intl

$330United Airlines

Thu, Jan 21 - Sat, Jan 23

12:25 pm - 6:14 pmDSM Des Moines-GSP Greenville

4h 49m1 stop Detroit Metropolitan Wayne County

7:10 am - 11:27 amGSP Greenville-DSM Des Moines

5h 17m1 stop Detroit Metropolitan Wayne County

$347Delta

Tue, Feb 23 - Wed, Mar 3

11:32 am - 7:05 pmDSM Des Moines-GSP Greenville

6h 33m1 stop Atlanta Hartsfield-Jackson

5:37 am - 10:45 amGSP Greenville-DSM Des Moines

6h 08m1 stop Atlanta Hartsfield-Jackson

$347Delta

Tue, Feb 23 - Tue, Mar 2

1:55 pm - 8:02 pmCID Cedar Rapids-GSP Greenville

5h 07m1 stop Chicago O'Hare Intl

11:42 am - 5:48 pmGSP Greenville-CID Cedar Rapids

7h 06m1 stop Chicago O'Hare Intl

$349American Airlines

Fri, Jan 1 - Fri, Jan 8

6:15 am - 2:22 pmDSM Des Moines-GSP Greenville

7h 07m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

12:35 pm - 9:28 pmGSP Greenville-DSM Des Moines

9h 53m2 stops Newark Chicago O'Hare Intl

$370United Airlines

Thu, Jan 21 - Sat, Jan 23

7:00 am - 6:10 pmDSM Des Moines-GSP Greenville

10h 10m2 stops Denver Intl Nashville Intl

2:50 pm - 10:05 pmGSP Greenville-DSM Des Moines

8h 15m2 stops Baltimore/Washington Chicago Midway

$387Southwest

Mon, Dec 7 - Mon, Dec 14

7:30 am - 12:15 pmDSM Des Moines-GSP Greenville

3h 45m1 stop Nashville Intl

7:15 am - 10:10 amGSP Greenville-DSM Des Moines

3h 55m1 stop Nashville Intl

$397Southwest

Sun, Feb 21 - Wed, Mar 3

1:15 pm - 8:59 pmDSM Des Moines-GSP Greenville

6h 44m1 stop Chicago O'Hare Intl

6:30 am - 10:37 amGSP Greenville-DSM Des Moines

5h 07m1 stop Chicago O'Hare Intl

$425United Airlines

Mon, Dec 7 - Wed, Dec 9

Cheap last minute flights

Enter your travel dates to find the best prices.

12:46 pm - 7:53 amDSM Des Moines-GSP Greenville

18h 07m1 stop Orlando Sanford Intl

8:47 pm - 9:30 amGSP Greenville-DSM Des Moines

37h 43m2 stops Tampa Nashville Intl

$541Multiple Airlines

Wed, Nov 11 - Wed, Nov 18

4:15 pm - 8:13 amDSM Des Moines-GSP Greenville

14h 58m1 stop Fort Lauderdale

8:04 pm - 9:45 pmGSP Greenville-DSM Des Moines

26h 41m1 stop Fort Myers SW Florida Intl

$558Multiple Airlines

Thu, Nov 12 - Sun, Nov 15

4:15 pm - 8:13 amDSM Des Moines-GSP Greenville

14h 58m1 stop Fort Lauderdale

4:02 pm - 7:35 pmGSP Greenville-DSM Des Moines

28h 33m2 stops Orlando Denver Intl

$623Multiple Airlines

Thu, Nov 12 - Sun, Nov 15

11:09 am - 6:55 pmDSM Des Moines-GSP Greenville

6h 46m1 stop Charlotte Douglas

3:35 pm - 10:36 pmGSP Greenville-DSM Des Moines

8h 01m1 stop Washington, D.C. Reagan-National

$742American Airlines

Wed, Nov 11 - Wed, Nov 18

7:00 am - 6:10 pmDSM Des Moines-GSP Greenville

10h 10m2 stops Denver Intl Nashville Intl

2:50 pm - 10:05 pmGSP Greenville-DSM Des Moines

8h 15m2 stops Baltimore/Washington Chicago Midway

$752Southwest

Wed, Nov 11 - Wed, Nov 18

3:14 pm - 8:58 pmCID Cedar Rapids-GSP Greenville

4h 44m1 stop Chicago O'Hare Intl

10:42 am - 10:24 amGSP Greenville-CID Cedar Rapids

24h 42m1 stop Chicago O'Hare Intl

$763United Airlines

Mon, Nov 16 - Fri, Nov 20

10:00 am - 7:01 pmCID Cedar Rapids-GSP Greenville

8h 01m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

10:42 am - 10:24 amGSP Greenville-CID Cedar Rapids

24h 42m1 stop Chicago O'Hare Intl

$768United Airlines

Mon, Nov 16 - Fri, Nov 20

3:14 pm - 8:58 pmCID Cedar Rapids-GSP Greenville

4h 44m1 stop Chicago O'Hare Intl

10:42 am - 10:24 amGSP Greenville-CID Cedar Rapids

24h 42m1 stop Chicago O'Hare Intl

$778United Airlines

Mon, Nov 16 - Fri, Nov 20

6:00 am - 7:01 pmCID Cedar Rapids-GSP Greenville

12h 01m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

10:42 am - 10:24 amGSP Greenville-CID Cedar Rapids

24h 42m1 stop Chicago O'Hare Intl

$783United Airlines

Mon, Nov 16 - Fri, Nov 20

5:30 am - 7:01 pmDSM Des Moines-GSP Greenville

12h 31m2 stops Denver Intl Washington, D.C. Dulles Intl

10:26 am - 9:55 pmGSP Greenville-DSM Des Moines

12h 29m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$808United Airlines

Thu, Nov 12 - Sun, Nov 15

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American Airlines flights from Iowa to Greenville

Our best American Airlines deals on Iowa to Greenville flight tickets

American Airlines

Jan 21

DSM10:57 amDes Moines

4h 54m

1 stop

GSP4:51 pmGreenville

Jan 23

GSP7:10 amGreenville

8h 38m

1 stop

DSM2:48 pmDes Moines

$325

American Airlines

Jan 1

CID1:55 pmCedar Rapids

5h 07m

1 stop

GSP8:02 pmGreenville

Jan 8

GSP11:42 amGreenville

7h 06m

1 stop

CID5:48 pmCedar Rapids

$349

American Airlines

Dec 10

DSM7:14 amDes Moines

7h 56m

1 stop

GSP4:10 pmGreenville

Dec 13

GSP5:17 pmGreenville

6h 48m

1 stop

DSM11:05 pmDes Moines

$359

United Airlines flights from Iowa to Greenville

Our best United Airlines deals on Iowa to Greenville flight tickets

United Airlines

Jan 21

DSM12:52 pmDes Moines

9h 42m

2 stops

GSP11:34 pmGreenville

Jan 23

GSP6:30 amGreenville

6h 47m

1 stop

DSM12:17 pmDes Moines

$330

United Airlines

Jan 21

DSM6:15 amDes Moines

7h 07m

2 stops

GSP2:22 pmGreenville

Jan 23

GSP12:35 pmGreenville

9h 53m

2 stops

DSM9:28 pmDes Moines

$370

United Airlines

Dec 7

DSM1:15 pmDes Moines

6h 44m

1 stop

GSP8:59 pmGreenville

Dec 9

GSP6:30 amGreenville

5h 07m

1 stop

DSM10:37 amDes Moines

$425

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesGreenville

DSM Des Moines - GSP Greenville

DSMGSP

Des Moines

Thu 1/21

10:57 am-4:51 pm

1 stop4h 54m

Greenville

Sat 1/23

7:10 am-2:48 pm

1 stop8h 38m

$325

Des MoinesGreenville

DSM Des Moines - GSP Greenville

DSMGSP

Des Moines

Sat 1/23

8:07 am-1:15 pm

1 stop4h 08m

Greenville

Sat 1/23

5:21 pm-11:03 pm

1 stop6h 42m

$325

Des MoinesGreenville

DSM Des Moines - GSP Greenville

DSMGSP

Des Moines

Thu 1/21

12:52 pm-11:34 pm

2 stops9h 42m

Greenville

Sat 1/23

6:30 am-12:17 pm

1 stop6h 47m

$330

Des MoinesGreenville

DSM Des Moines - GSP Greenville

DSMGSP

Des Moines

Tue 2/23

12:25 pm-6:14 pm

1 stop4h 49m

Greenville

Wed 3/3

7:10 am-11:27 am

1 stop5h 17m

$347

Des MoinesGreenville

DSM Des Moines - GSP Greenville

DSMGSP

Des Moines

Tue 2/23

11:32 am-7:05 pm

1 stop6h 33m

Greenville

Tue 3/2

5:37 am-10:45 am

1 stop6h 08m

$347

Cedar RapidsGreenville

CID Cedar Rapids - GSP Greenville

CIDGSP

Cedar Rapids

Fri 1/1

1:55 pm-8:02 pm

1 stop5h 07m

Greenville

Fri 1/8

11:42 am-5:48 pm

1 stop7h 06m

$349

Des MoinesGreenville

DSM Des Moines - GSP Greenville

DSMGSP

Des Moines

Thu 1/21

6:15 am-2:22 pm

2 stops7h 07m

Greenville

Sat 1/23

12:35 pm-9:28 pm

2 stops9h 53m

$370

Des MoinesGreenville

DSM Des Moines - GSP Greenville

DSMGSP

Des Moines

Mon 12/7

7:00 am-6:10 pm

2 stops10h 10m

Greenville

Mon 12/14

2:50 pm-10:05 pm

2 stops8h 15m

$387

Quickest round-trip

Des MoinesGreenville

DSM Des Moines - GSP Greenville

DSMGSP

Des Moines

Sun 2/21

7:30 am-12:15 pm

1 stop3h 45m

Greenville

Wed 3/3

7:15 am-10:10 am

1 stop3h 55m

$397

Des MoinesGreenville

DSM Des Moines - GSP Greenville

DSMGSP

Des Moines

Mon 12/7

1:15 pm-8:59 pm

1 stop6h 44m

Greenville

Wed 12/9

6:30 am-10:37 am

1 stop5h 07m

$425

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Iowa to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Greenville?

The month of September is another great option to travel to Greenville, with average flight prices from Iowa averaging around $308.

Cheap Iowa to Greenville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Greenville

Best Price Found	$148
Fastest flight time	4h 17m
Direct flights	None

The best one-way flight to Greenville from Iowa in the past 72 hours is $148. The best round-trip flight deal from Iowa to Greenville found on momondo in the last 72 hours is $325.

The fastest flight from Iowa to Greenville takes 4h 17m

There are no direct flights from Iowa to Greenville. There are no popular flight routes from Iowa to Greenville.

Search flight deals

Frequently asked questions about flying from Iowa to Greenville

When did momondo last update prices for flights from Iowa to Greenville Airport?
Prices for flights from Iowa to Greenville Airport were last updated today.
How many operators does momondo search for flights from Iowa to Greenville Airport?
There are 3 operators available for flights from Iowa to Greenville Airport as of November 2026.
How old do you have to be to fly from Iowa to Greenville Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Greenville Airport.
What documentation or ID do you need to fly to Greenville Airport?
The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Iowa to Greenville

Compare and see reviews for airlines that fly from Iowa to Greenville with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $260	Free Cancellation	Rating 7.3 10,471 reviews	Search United Airlines flights
American Airlines	PriceFrom $268	Free Cancellation	Rating 7.0 12,224 reviews	Search American Airlines flights
Delta	PriceFrom $316	Free Cancellation	Rating 7.8 8,700 reviews	Search Delta flights

Anderson

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Simpsonville

Greer

Duncan

Seneca

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from Iowa.

Can I find flights from Iowa to Greenville with flexible booking policies on momondo?

All flight searches from Iowa to Greenville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Iowa to Greenville?

momondo provides multiple filters to help you find the best flight to Greenville from Iowa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Iowa to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Iowa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from Iowa to Greenville from $148

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Greenville departing on 11/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Why use momondo?

An easier way to manage your Greenville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

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