Cheap flights from Indiana to Panama City from $104

The cheapest month to fly to Panama City, Florida from Indiana is in February. Flight prices, which tend to average around $353, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Panama City, Florida, with average flight prices from Indiana averaging around $360.

Our data shows that Sunday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $399. On the other hand, Saturday is the most expensive day to depart from Indiana because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $429.

Fly from Indianapolis to Panama City NW Florida Beaches for the best Indiana - Panama City NW Florida Beaches flight prices

You are more likely to see cheaper flights to Panama City, Florida from Indiana when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $383 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Indiana for as low as $317 on momondo.

There is only 1 cabin class available to choose from on Indiana to Panama City, Florida flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 19% on your flight if you consider stops on a Indiana to Panama City, Florida flight.

Delta, Southwest, and United Airlines are the most popular carriers operating from Indiana to Panama City NW Florida Beaches

Delta, American Airlines and Allegiant Air are the top three most popular airlines that fly to Panama City, Florida from Indiana according to our data. Delta is the first choice among our users, with 42% of people opting to fly with this airline when traveling to Panama City, Florida. Keep in mind that there are 5 different airlines that fly to Panama City, Florida on a routine basis, so you have a few additional options to choose from.

The number of flights available between Indiana and Panama City, Florida is 2 per day as of August 2026. The most frequent departure time is 7:00AM, with 100% of daily flights leaving at noon.

The number of flights available between Indiana and Panama City, Florida is 16 per week as of August 2026. The most frequent departure day is Mon, with 19% of weekly flights leaving on this day.