Cheap flights from Indiana to Key West from $45

In general, May is the cheapest month to fly from Indiana to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $210. If you are unable to visit Key West during the month of May, then departing from Indiana during the month July is also very affordable. Most momondo users find prices during this month for around $243.

On average, the least expensive day to fly to Key West from Indiana is on a Tuesday. momondo users have found tickets for Tuesday departures for as low as $204. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Indiana to Key West for around $565.

According to our data, the cheapest time of day to fly to Key West is at noon. momondo users have found flights departing from Indiana to Key West at noon for as low as $219. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Key West are more costly in the afternoon, with an average ticket price of $757. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Indianapolis to Key West for the best Indiana - Key West flight prices

You are more likely to see cheaper flights to Key West from Indiana when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $332 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Indiana for as low as $239 on momondo.

There is only 1 cabin class available to choose from on Indiana to Key West flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Allegiant Air, Spirit Airlines, and Breeze Airways are the most popular carriers operating from Indiana to Key West

American Airlines, Allegiant Air and Delta are the top three most popular airlines that fly to Key West from Indiana according to our data. American Airlines is the first choice among our users, with 41% of people opting to fly with this airline when traveling to Key West. Keep in mind that there are 5 different airlines that fly to Key West on a routine basis, so you have a few additional options to choose from.

As of April 2026, 33 flights take off from Indiana and land in Key West each week. The most common flight departure day for this route is Sat, with 18% of weekly flights taking off on this day.

If you’re flying from a popular airport in Indiana, such as Indianapolis or Fort Wayne, and flying into Key West, then you can expect flight times to average 2h 35m and 4h 46m, respectively.