Cheap flights from Greenville to Detroit from $105

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Detroit departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:43 pm - 11:46 pm
GSP
-
DTW
30h 03m
1 stop
Multiple Airlines Logo
5:09 pm - 9:48 am
DTW
-
GSP
16h 39m
2 stops
$225Multiple Airlines
Mon, Apr 13 - Sat, Apr 18
Multiple Airlines Logo
5:43 pm - 9:23 am
GSP
-
DTW
15h 40m
1 stop
Multiple Airlines Logo
8:43 pm - 7:38 pm
DTW
-
GSP
22h 55m
2 stops
$252Multiple Airlines
Mon, Apr 13 - Thu, Apr 16
Multiple Airlines Logo
5:43 pm - 11:46 pm
GSP
-
DTW
30h 03m
1 stop
Multiple Airlines Logo
5:25 pm - 9:48 am
DTW
-
GSP
16h 23m
1 stop
$257Multiple Airlines
Mon, Apr 13 - Sat, Apr 18
Multiple Airlines Logo
5:43 pm - 9:23 am
GSP
-
DTW
15h 40m
1 stop
Multiple Airlines Logo
7:05 pm - 3:04 pm
DTW
-
GSP
19h 59m
2 stops
$262Multiple Airlines
Mon, Apr 13 - Wed, Apr 15
Multiple Airlines Logo
5:43 pm - 12:46 am
GSP
-
DTW
7h 03m
1 stop
Multiple Airlines Logo
10:10 pm - 8:07 pm
DTW
-
GSP
21h 57m
1 stop
$269Multiple Airlines
Fri, Apr 17 - Sun, Apr 19
Multiple Airlines Logo
5:43 pm - 12:46 am
GSP
-
DTW
7h 03m
1 stop
Multiple Airlines Logo
10:10 pm - 8:07 pm
DTW
-
GSP
21h 57m
1 stop
$284Multiple Airlines
Fri, Apr 17 - Sun, Apr 19
Multiple Airlines Logo
5:43 pm - 12:39 am
GSP
-
DTW
6h 56m
1 stop
Multiple Airlines Logo
6:59 pm - 8:07 pm
DTW
-
GSP
25h 08m
1 stop
$286Multiple Airlines
Fri, Apr 10 - Sun, Apr 12
Multiple Airlines Logo
5:43 pm - 11:46 pm
GSP
-
DTW
30h 03m
1 stop
Multiple Airlines Logo
12:57 pm - 7:38 pm
DTW
-
GSP
6h 41m
1 stop
$293Multiple Airlines
Mon, Apr 13 - Fri, Apr 17
Multiple Airlines Logo
5:43 pm - 9:23 am
GSP
-
DTW
15h 40m
1 stop
Multiple Airlines Logo
8:43 pm - 7:38 pm
DTW
-
GSP
22h 55m
2 stops
$297Multiple Airlines
Mon, Apr 13 - Thu, Apr 16
Multiple Airlines Logo
5:43 pm - 12:46 am
GSP
-
DTW
7h 03m
1 stop
Multiple Airlines Logo
5:09 pm - 4:53 pm
DTW
-
GSP
23h 44m
2 stops
$302Multiple Airlines
Fri, Apr 17 - Sun, Apr 19

Southwest flights from Greenville to Detroit

Our best Southwest deals on Greenville to Detroit flight tickets
Southwest
Apr 14
GSP5:05 pmGreenville
4h 30m
1 stop
DTW9:35 pmDetroit Metropolitan Wayne County
Apr 21
DTW4:10 pmDetroit Metropolitan Wayne County
5h 30m
1 stop
GSP9:40 pmGreenville
$359
Southwest
Apr 14
GSP12:50 pmGreenville
9h 40m
2 stops
DTW10:30 pmDetroit Metropolitan Wayne County
Apr 21
DTW4:10 pmDetroit Metropolitan Wayne County
5h 30m
1 stop
GSP9:40 pmGreenville
$364
Southwest
Apr 30
GSP6:25 pmGreenville
3h 55m
1 stop
DTW10:20 pmDetroit Metropolitan Wayne County
May 6
DTW6:10 amDetroit Metropolitan Wayne County
6h 00m
1 stop
GSP12:10 pmGreenville
$367

United Airlines flights from Greenville to Detroit

Our best United Airlines deals on Greenville to Detroit flight tickets
United Airlines
Apr 4
GSP5:41 pmGreenville
4h 36m
1 stop
DTW10:17 pmDetroit Metropolitan Wayne County
Apr 8
DTW6:00 amDetroit Metropolitan Wayne County
5h 54m
1 stop
GSP11:54 amGreenville
$559
United Airlines
Apr 2
GSP5:41 pmGreenville
7h 35m
1 stop
DTW1:16 amDetroit Metropolitan Wayne County
Apr 7
DTW12:11 pmDetroit Metropolitan Wayne County
6h 48m
2 stops
GSP6:59 pmGreenville
$564
United Airlines
Mar 26
GSP6:30 amGreenville
11h 37m
2 stops
DTW6:07 pmDetroit Metropolitan Wayne County
Mar 29
DTW5:50 amDetroit Metropolitan Wayne County
5h 54m
1 stop
GSP11:44 amGreenville
$664

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 21, 2026.
Use the filters below to find and compare flights from Greenville to Detroit that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Mon 4/13

5:43 pm-11:46 pm

1 stop30h 03m

Detroit Metropolitan Wayne County

Sat 4/18

5:09 pm-9:48 am

2 stops16h 39m

$225

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Mon 4/13

5:43 pm-9:23 am

1 stop15h 40m

Detroit Metropolitan Wayne County

Thu 4/16

8:43 pm-7:38 pm

2 stops22h 55m

$252

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Mon 4/13

5:43 pm-11:46 pm

1 stop30h 03m

Detroit Metropolitan Wayne County

Sat 4/18

5:25 pm-9:48 am

1 stop16h 23m

$257

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Mon 4/13

5:43 pm-9:23 am

1 stop15h 40m

Detroit Metropolitan Wayne County

Wed 4/15

7:05 pm-3:04 pm

2 stops19h 59m

$262
Quickest round-trip

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Fri 4/17

5:43 pm-12:46 am

1 stop7h 03m

Detroit Metropolitan Wayne County

Sun 4/19

10:10 pm-8:07 pm

1 stop21h 57m

$269

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Fri 4/17

5:43 pm-12:46 am

1 stop7h 03m

Detroit Metropolitan Wayne County

Sun 4/19

10:10 pm-8:07 pm

1 stop21h 57m

$284

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Fri 4/10

5:43 pm-12:39 am

1 stop6h 56m

Detroit Metropolitan Wayne County

Sun 4/12

6:59 pm-8:07 pm

1 stop25h 08m

$286

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Mon 4/13

5:43 pm-11:46 pm

1 stop30h 03m

Detroit Metropolitan Wayne County

Fri 4/17

12:57 pm-7:38 pm

1 stop6h 41m

$293

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Mon 4/13

5:43 pm-9:23 am

1 stop15h 40m

Detroit Metropolitan Wayne County

Thu 4/16

8:43 pm-7:38 pm

2 stops22h 55m

$297

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Fri 4/17

5:43 pm-12:46 am

1 stop7h 03m

Detroit Metropolitan Wayne County

Sun 4/19

5:09 pm-4:53 pm

2 stops23h 44m

$302

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Greenville to Detroit

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and Detroit?

What is the cheapest month to fly to Detroit?

The cheapest month to fly to Detroit from Greenville is in June. Flight prices, which tend to average around $399, are often lower during this time because this is during the off-season. If you’re not able to fly to Detroit in June, then September is your next best option. Flight prices from Greenville to Detroit during September average around $399.

What is the cheapest day to depart on your flight to Detroit?

On average, the least expensive day to fly to Detroit from Greenville is on a Thursday. momondo users have found tickets for Thursday departures for as low as $451. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Greenville to Detroit for around $637.

What is the cheapest time of day to depart on your flight to Detroit?

In the morning is the cheapest time of day to fly from Greenville to Detroit when you can find flight prices for as low as $466. Flying to Detroit in the morning is an ideal time because this is during off-peak travel hours. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $670 on average. Flights to Detroit from Greenville in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

What is the cheapest Greenville to Detroit flight route?

Fly from Greenville to Detroit Metropolitan Wayne County for the best Greenville - Detroit flight prices

What cabin class options are available on Greenville to Detroit flights?

There are 4 cabin classes available to choose from on Greenville to Detroit flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Greenville to Detroit flights?

You could potentially save up to 41% on your flight if you consider stops on a Greenville to Detroit flight.

When to book flights from Greenville to Detroit

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Detroit according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Detroit (GSP to DTT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Detroit

Best Price Found

$267

Fastest flight time

1h 44m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun

Airports in Detroit

1 airport
The best one-way flight to Detroit from Greenville in the past 72 hours is $267. The best round-trip flight deal from Greenville to Detroit found on momondo in the last 72 hours is $399.
The fastest flight from Greenville to Detroit takes 1h 44m
Direct flights go from Greenville to Detroit on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Detroit. From Greenville there are direct flights to Detroit Metropolitan Wayne County (DTW).
  • How far is Greenville to Detroit by plane?

    Detroit is 518.0 mi away from Greenville. Typically, this will take 1h 44m by plane in normal conditions.

  • When did momondo last update prices for flights from Greenville Airport to Detroit?

    Prices for flights from Greenville Airport to Detroit were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to Detroit?

  • How old do you have to be to fly from Greenville Airport to Detroit?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Detroit.

  • What documentation or ID do you need to fly to Detroit?

    The necessary travel and health documents for your Detroit trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Greenville to Detroit?

  • What is the most popular airline from Greenville to Detroit?

Best airlines flying from Greenville to Detroit

Compare and see reviews for airlines that fly from Greenville to Detroit with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $286Free CancellationRating
7.1
11,488 reviews
Search American Airlines flights
DeltaPriceFrom $399Free CancellationRating
7.9
8,313 reviews
Search Delta flights
  • Delta Flights From Greenville to Detroit

    Across 14 Delta flights from Greenville to Detroit this week, the average price was $474, with the best Delta deals starting from $399 round-trip. 8,313 users have rated Delta on momondo, with an average score of 7.9/10.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Roseville
Port Huron

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Detroit?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Greenville to Detroit. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Greenville to Detroit with flexible booking policies on momondo?

Yes. All flights to Detroit from Greenville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Greenville to Detroit?

Once you have performed a search for Greenville to Detroit flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Greenville to Detroit right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Detroit, momondo offers a useful price alert feature which will track prices for flights to Detroit from Greenville and alert you when they change.

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1 adult
Mon 4/20
Mon 4/27

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