Cheap flights from Greenville to Detroit from $106
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Detroit departing on 1/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Not ready to book? to track prices.Southwest flights from Greenville to Detroit Metropolitan Wayne County Airport
Our best Southwest deals on Greenville to Detroit Metropolitan Wayne County Airport flight tickets
Delta flights from Greenville to Detroit Metropolitan Wayne County Airport
Our best Delta deals on Greenville to Detroit Metropolitan Wayne County Airport flight tickets
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Use the filters below to find and compare flights from Greenville to Detroit Metropolitan Wayne County Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
GreenvilleDetroit
GSP Greenville - DTW Detroit Metropolitan Wayne County
GSPDTW
Greenville
Thu 11/19
8:44 am-11:37 pm
1 stop14h 53m
Detroit Metropolitan Wayne County
Sun 12/6
9:33 pm-8:13 am
1 stop10h 40m
GreenvilleDetroit
GSP Greenville - DTW Detroit Metropolitan Wayne County
GSPDTW
Greenville
Thu 11/19
10:12 am-11:37 pm
2 stops13h 25m
Detroit Metropolitan Wayne County
Sun 12/6
9:33 pm-2:08 pm
1 stop16h 35m
GreenvilleDetroit
GSP Greenville - DTW Detroit Metropolitan Wayne County
GSPDTW
Greenville
Thu 11/12
10:12 am-9:19 am
2 stops23h 07m
Detroit Metropolitan Wayne County
Sun 11/15
4:29 pm-10:51 am
1 stop18h 22m
GreenvilleDetroit
GSP Greenville - DTW Detroit Metropolitan Wayne County
GSPDTW
Greenville
Thu 11/12
10:12 am-5:53 pm
1 stop7h 41m
Detroit Metropolitan Wayne County
Sun 11/15
4:29 pm-8:13 am
1 stop15h 44m
GreenvilleDetroit
GSP Greenville - DTW Detroit Metropolitan Wayne County
GSPDTW
Greenville
Tue 10/27
8:30 am-12:30 pm
1 stop4h 00m
Detroit Metropolitan Wayne County
Wed 10/28
5:35 am-10:05 am
1 stop4h 30m
GreenvilleDetroit
GSP Greenville - DTW Detroit Metropolitan Wayne County
GSPDTW
Greenville
Wed 11/4
7:05 am-1:20 pm
1 stop6h 15m
Detroit Metropolitan Wayne County
Wed 11/11
1:25 pm-6:10 pm
1 stop4h 45m
GreenvilleDetroit
GSP Greenville - DTW Detroit Metropolitan Wayne County
GSPDTW
Greenville
Sat 11/7
8:25 am-1:00 pm
1 stop4h 35m
Detroit Metropolitan Wayne County
Wed 11/18
3:55 pm-7:55 pm
1 stop4h 00m
GreenvilleDetroit
GSP Greenville - DTW Detroit Metropolitan Wayne County
GSPDTW
Greenville
Wed 11/4
7:20 am-9:07 am
Nonstop1h 47m
Detroit Metropolitan Wayne County
Wed 11/11
8:25 am-10:11 am
Nonstop1h 46m
GreenvilleDetroit
GSP Greenville - DTW Detroit Metropolitan Wayne County
GSPDTW
Greenville
Thu 11/12
6:50 pm-8:46 pm
Nonstop1h 56m
Detroit Metropolitan Wayne County
Sat 11/14
10:35 am-12:19 pm
Nonstop1h 44m
GreenvilleDetroit
GSP Greenville - DTW Detroit Metropolitan Wayne County
GSPDTW
Greenville
Fri 10/30
6:57 pm-8:48 pm
Nonstop1h 51m
Detroit Metropolitan Wayne County
Wed 11/11
8:25 am-10:11 am
Nonstop1h 46m
See travel insights to Detroit from
How to get the cheapest flight ticket from Greenville to Detroit Metropolitan Wayne County Airport
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the typical price of a round-trip flight between Greenville and Detroit Metropolitan Wayne County Airport?
Prices are currently low for flights on this route.
Typical prices usually range from $421 to $533.The lowest price recently found on this route was $188.
What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?
The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Greenville is in March. Flight prices, which tend to average around $409, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of March, then book flights to Detroit Metropolitan Wayne County Airport from Greenville during August instead. Flights to Detroit Metropolitan Wayne County Airport in August, while not as cheap as those in March, still average around $429.
What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?
The cheapest day to depart from Greenville to Detroit Metropolitan Wayne County Airport is on a Friday when prices can be found for as low as $460. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Monday is $704.
What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?
Flying to Detroit Metropolitan Wayne County Airport from Greenville in the morning is the least expensive time of day to depart. momondo users have found prices as low as $483 when looking at flights departing in the morning. Flights to Detroit Metropolitan Wayne County Airport are more costly in the afternoon, with an average ticket price of $648. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.
What is the cheapest Greenville to Detroit Metropolitan Wayne County flight route?
Fly from Greenville to Detroit Metropolitan Wayne County for the best Greenville - Detroit Metropolitan Wayne County flight prices
What cabin class options are available on Greenville to Detroit Metropolitan Wayne County Airport flights?
There are 4 cabin classes available to choose from on Greenville to Detroit Metropolitan Wayne County Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.
Can stopping save me money on Greenville to Detroit Metropolitan Wayne County Airport flights?
No. A direct flight is the cheapest option for a flight between Greenville to Detroit Metropolitan Wayne County Airport.
What is the cheapest airline that flies from Greenville to Detroit Metropolitan Wayne County?
Southwest is the most popular carrier operating from Greenville to Detroit Metropolitan Wayne County
What airlines fly to Detroit Metropolitan Wayne County Airport?
American Airlines, Delta and Frontier are the top three most popular airlines that fly to Detroit Metropolitan Wayne County Airport from Greenville according to our data. American Airlines is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Detroit Metropolitan Wayne County Airport. Keep in mind that there are 6 different airlines that fly to Detroit Metropolitan Wayne County Airport on a routine basis, so you have a few additional options to choose from.
How many flights depart from Greenville to Detroit Metropolitan Wayne County Airport on average per day?
10 flights are operational daily from Greenville to Detroit Metropolitan Wayne County Airport as of October 2026. The most popular departure time for this route is 7:00AM, with 64% of flights per day taking off at noon.
How many flights depart from Greenville to Detroit Metropolitan Wayne County Airport on average per week?
The number of flights available between Greenville and Detroit Metropolitan Wayne County Airport is 76 per week as of October 2026. The most frequent departure day is Mon, with 16% of weekly flights leaving on this day.
When to book flights from Greenville to Detroit Metropolitan Wayne County Airport
Cheap Greenville to Detroit Metropolitan Wayne County Airport (GSP to DTW) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Greenville to Detroit Metropolitan Wayne County Airport
Frequently asked questions about flying from Greenville to Detroit Metropolitan Wayne County Airport
How far is Greenville to Detroit Metropolitan Wayne County by plane?
Greenville and Detroit Metropolitan Wayne County are 511.4 mi apart from one another. By plane, this route typically takes 1h 47m.
When did momondo last update prices for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?
Prices for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport were last updated today.
How many operators does momondo search for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?
The number of operators available for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport is 2 as of October 2026.
How old do you have to be to fly from Greenville Airport to Detroit Metropolitan Wayne County Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Detroit Metropolitan Wayne County Airport.
What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?
The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Greenville to Detroit Metropolitan Wayne County Airport?
momondo data reveals that the most frequently booked plane model on the route from Greenville to Detroit Metropolitan Wayne County Airport is Boeing 717-200, representing 31.61% of all bookings. The subsequent popular models are Canadair (Bombardier) Regional Jet 700 at 31.03%, Canadair (Bombardier) Regional Jet 900 at 23.56%, and Airbus A320-100/200 at 4.02%.
What is the most popular airline from Greenville to Detroit Metropolitan Wayne County Airport?
Based on momondo bookings for flights between Greenville and Detroit Metropolitan Wayne County Airport, the leading airline is Delta, making up 90% of the total bookings. Other popular airlines include Southwest with 10%.
Best airlines flying from Greenville to Detroit Metropolitan Wayne County Airport
Compare and see reviews for airlines that fly from Greenville to Detroit Metropolitan Wayne County Airport with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $222 | Free Cancellation | Rating 7.9 4,227 reviews | |||
| PriceFrom $399 | Free Cancellation | Rating 7.8 8,653 reviews |
Delta Flights From Greenville to Detroit Metropolitan Wayne County Airport
The lowest priced Delta flight from Greenville to Detroit Metropolitan Wayne County Airport from the last 72 hours was $399. Generally, Delta has 19 flights on this route every week with an average price of $484. Delta is rated 7.8/10 by our users.
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Why should I use momondo to find a flight deal from Greenville to Detroit?
It is quick and easy to find Greenville to Detroit flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Detroit that suits you.
Can I find flights from Greenville to Detroit with flexible booking policies on momondo?
Flights from Greenville to Detroit with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.
How can momondo help me find flights from Greenville to Detroit?
momondo helps you find the best flight between Greenville and Detroit by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.
I’m not ready to book a flight from Greenville to Detroit right now. Can momondo alert me if prices change?
Yes. momondo can track prices for Greenville to Detroit flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.