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Cheap flights from Greenville to Detroit from $78

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Detroit departing on 10/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Greenville to Detroit

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:03 pm - 11:27 pmGSP  Greenville-DTW Detroit Metropolitan Wayne County
28h 24m2 stops Tampa Fort Lauderdale
Multiple Airlines Logo
4:23 pm - 5:14 pmDTW  Detroit Metropolitan Wayne County-GSP Greenville
24h 51m1 stop Fort Lauderdale
$155Multiple Airlines
Mon, Sep 14 - Mon, Sep 21
Multiple Airlines Logo
7:03 pm - 11:27 pmGSP  Greenville-DTW Detroit Metropolitan Wayne County
28h 24m2 stops Tampa Fort Lauderdale
Multiple Airlines Logo
4:23 pm - 5:14 pmDTW  Detroit Metropolitan Wayne County-GSP Greenville
24h 51m1 stop Fort Lauderdale
$156Multiple Airlines
Mon, Sep 14 - Mon, Sep 21
Multiple Airlines Logo
2:38 pm - 11:27 pmGSP  Greenville-DTW Detroit Metropolitan Wayne County
8h 49m1 stop Fort Lauderdale
Multiple Airlines Logo
4:23 pm - 5:14 pmDTW  Detroit Metropolitan Wayne County-GSP Greenville
24h 51m1 stop Fort Lauderdale
$159Multiple Airlines
Thu, Oct 1 - Mon, Oct 5
Multiple Airlines Logo
2:38 pm - 11:27 pmGSP  Greenville-DTW Detroit Metropolitan Wayne County
8h 49m1 stop Fort Lauderdale
Multiple Airlines Logo
4:23 pm - 5:14 pmDTW  Detroit Metropolitan Wayne County-GSP Greenville
24h 51m1 stop Fort Lauderdale
$160Multiple Airlines
Thu, Oct 1 - Mon, Oct 5
Multiple Airlines Logo
7:03 pm - 11:27 pmGSP  Greenville-DTW Detroit Metropolitan Wayne County
28h 24m2 stops Tampa Fort Lauderdale
Multiple Airlines Logo
4:23 pm - 6:30 pmDTW  Detroit Metropolitan Wayne County-GSP Greenville
26h 07m1 stop Fort Lauderdale
$161Multiple Airlines
Mon, Sep 14 - Sun, Sep 20
Multiple Airlines Logo
2:38 pm - 11:27 pmGSP  Greenville-DTW Detroit Metropolitan Wayne County
8h 49m1 stop Fort Lauderdale
Multiple Airlines Logo
4:23 pm - 2:00 pmDTW  Detroit Metropolitan Wayne County-GSP Greenville
21h 37m1 stop Fort Lauderdale
$163Multiple Airlines
Thu, Oct 1 - Sun, Oct 4
Multiple Airlines Logo
7:03 pm - 10:43 amGSP  Greenville-DTW Detroit Metropolitan Wayne County
15h 40m1 stop Tampa
Multiple Airlines Logo
4:23 pm - 5:14 pmDTW  Detroit Metropolitan Wayne County-GSP Greenville
24h 51m1 stop Fort Lauderdale
$163Multiple Airlines
Mon, Sep 14 - Mon, Sep 21
Multiple Airlines Logo
2:18 pm - 11:27 pmGSP  Greenville-DTW Detroit Metropolitan Wayne County
9h 09m1 stop Fort Lauderdale
Multiple Airlines Logo
4:23 pm - 2:28 pmDTW  Detroit Metropolitan Wayne County-GSP Greenville
22h 05m1 stop Fort Lauderdale
$164Multiple Airlines
Fri, Sep 18 - Sun, Sep 20
Delta Logo
7:00 am - 8:52 amGSP  Greenville-DTW Detroit Metropolitan Wayne County
1h 52mnonstop
Delta Logo
8:05 pm - 9:49 pmDTW  Detroit Metropolitan Wayne County-GSP Greenville
1h 44mnonstop
$399Delta
Tue, Nov 24 - Fri, Nov 27
Delta Logo
7:15 am - 9:01 amGSP  Greenville-DTW Detroit Metropolitan Wayne County
1h 46mnonstop
Delta Logo
8:30 am - 10:24 amDTW  Detroit Metropolitan Wayne County-GSP Greenville
1h 54mnonstop
$399Delta
Tue, Sep 22 - Sun, Sep 27

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Southwest flights from Greenville to Detroit Metropolitan Wayne County Airport

Our best Southwest deals on Greenville to Detroit Metropolitan Wayne County Airport flight tickets
Southwest
Aug 20
GSP6:55 pmGreenville
3h 40m
1 stop
DTW10:35 pmDetroit Metropolitan Wayne County
Aug 25
DTW6:00 amDetroit Metropolitan Wayne County
6h 25m
1 stop
GSP12:25 pmGreenville
$447
Southwest
Aug 20
GSP7:00 amGreenville
8h 10m
2 stops
DTW3:10 pmDetroit Metropolitan Wayne County
Aug 23
DTW3:15 pmDetroit Metropolitan Wayne County
7h 25m
2 stops
GSP10:40 pmGreenville
$509
Southwest
Aug 10
GSP1:05 pmGreenville
9h 10m
2 stops
DTW10:15 pmDetroit Metropolitan Wayne County
Aug 29
DTW6:35 amDetroit Metropolitan Wayne County
5h 40m
2 stops
GSP12:15 pmGreenville
$522

Delta flights from Greenville to Detroit Metropolitan Wayne County Airport

Our best Delta deals on Greenville to Detroit Metropolitan Wayne County Airport flight tickets
Delta
Aug 20
GSP7:15 amGreenville
1h 47m
DTW9:02 amDetroit Metropolitan Wayne County
Aug 25
DTW7:45 pmDetroit Metropolitan Wayne County
1h 41m
GSP9:26 pmGreenville
$469
Delta
Aug 20
GSP5:20 pmGreenville
5h 13m
1 stop
DTW10:33 pmDetroit Metropolitan Wayne County
Aug 25
DTW7:45 pmDetroit Metropolitan Wayne County
1h 41m
GSP9:26 pmGreenville
$479
Delta
Aug 10
GSP7:15 amGreenville
1h 47m
DTW9:02 amDetroit Metropolitan Wayne County
Aug 29
DTW10:10 amDetroit Metropolitan Wayne County
1h 41m
GSP11:51 amGreenville
$539

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Greenville to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleDetroit

GSP Greenville - DTW Detroit Metropolitan Wayne County

GSPDTW

Greenville

Mon 9/14

7:03 pm-11:27 pm

2 stops28h 24m

Detroit Metropolitan Wayne County

Mon 9/21

4:23 pm-5:14 pm

1 stop24h 51m

$155

GreenvilleDetroit

GSP Greenville - DTW Detroit Metropolitan Wayne County

GSPDTW

Greenville

Mon 9/14

7:03 pm-11:27 pm

2 stops28h 24m

Detroit Metropolitan Wayne County

Mon 9/21

4:23 pm-5:14 pm

1 stop24h 51m

$156

GreenvilleDetroit

GSP Greenville - DTW Detroit Metropolitan Wayne County

GSPDTW

Greenville

Thu 10/1

2:38 pm-11:27 pm

1 stop8h 49m

Detroit Metropolitan Wayne County

Mon 10/5

4:23 pm-5:14 pm

1 stop24h 51m

$159

GreenvilleDetroit

GSP Greenville - DTW Detroit Metropolitan Wayne County

GSPDTW

Greenville

Thu 10/1

2:38 pm-11:27 pm

1 stop8h 49m

Detroit Metropolitan Wayne County

Mon 10/5

4:23 pm-5:14 pm

1 stop24h 51m

$160

GreenvilleDetroit

GSP Greenville - DTW Detroit Metropolitan Wayne County

GSPDTW

Greenville

Mon 9/14

7:03 pm-11:27 pm

2 stops28h 24m

Detroit Metropolitan Wayne County

Sun 9/20

4:23 pm-6:30 pm

1 stop26h 07m

$161

GreenvilleDetroit

GSP Greenville - DTW Detroit Metropolitan Wayne County

GSPDTW

Greenville

Thu 10/1

2:38 pm-11:27 pm

1 stop8h 49m

Detroit Metropolitan Wayne County

Sun 10/4

4:23 pm-2:00 pm

1 stop21h 37m

$163

GreenvilleDetroit

GSP Greenville - DTW Detroit Metropolitan Wayne County

GSPDTW

Greenville

Mon 9/14

7:03 pm-10:43 am

1 stop15h 40m

Detroit Metropolitan Wayne County

Mon 9/21

4:23 pm-5:14 pm

1 stop24h 51m

$163

GreenvilleDetroit

GSP Greenville - DTW Detroit Metropolitan Wayne County

GSPDTW

Greenville

Fri 9/18

2:18 pm-11:27 pm

1 stop9h 09m

Detroit Metropolitan Wayne County

Sun 9/20

4:23 pm-2:28 pm

1 stop22h 05m

$164
Quickest round-trip

GreenvilleDetroit

GSP Greenville - DTW Detroit Metropolitan Wayne County

GSPDTW

Greenville

Tue 11/24

7:00 am-8:52 am

Nonstop1h 52m

Detroit Metropolitan Wayne County

Fri 11/27

8:05 pm-9:49 pm

Nonstop1h 44m

$399

GreenvilleDetroit

GSP Greenville - DTW Detroit Metropolitan Wayne County

GSPDTW

Greenville

Tue 9/22

7:15 am-9:01 am

Nonstop1h 46m

Detroit Metropolitan Wayne County

Sun 9/27

8:30 am-10:24 am

Nonstop1h 54m

$399

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Greenville to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and Detroit Metropolitan Wayne County Airport?

Prices are currently low for flights on this route.

Typical prices usually range from $409 to $689.
The lowest price recently found on this route was $155.

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Greenville is in March. Flight prices, which tend to average around $409, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of March, then book flights to Detroit Metropolitan Wayne County Airport from Greenville during December instead. Flights to Detroit Metropolitan Wayne County Airport in December, while not as cheap as those in March, still average around $439.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Greenville to Detroit Metropolitan Wayne County Airport is on a Saturday when prices can be found for as low as $464. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Monday is $683.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Greenville in the morning is the least expensive time of day to depart. momondo users have found prices as low as $484 when looking at flights departing in the morning. Flights to Detroit Metropolitan Wayne County Airport are more costly in the afternoon, with an average ticket price of $654. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Greenville to Detroit Metropolitan Wayne County flight route?

Fly from Greenville to Detroit Metropolitan Wayne County for the best Greenville - Detroit Metropolitan Wayne County flight prices

What cabin class options are available on Greenville to Detroit Metropolitan Wayne County Airport flights?

There are 4 cabin classes available to choose from on Greenville to Detroit Metropolitan Wayne County Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Greenville to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 54% on your flight if you consider stops on a Greenville to Detroit Metropolitan Wayne County Airport flight.

How have Greenville to Detroit Metropolitan Wayne County Airport flight prices changed over time?

As of August 2026, prices for Greenville to Detroit Metropolitan Wayne County Airport flights are approximately 18% more expensive when compared to flights at the same time last year.

When to book flights from Greenville to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Detroit Metropolitan Wayne County Airport (GSP to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Detroit Metropolitan Wayne County Airport

Best Price Found

$261

Fastest flight time

1h 44m

Direct flights

Every day
The best one-way flight to Detroit Metropolitan Wayne County Airport from Greenville in the past 72 hours is $261. The best round-trip flight deal from Greenville to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $371.
The fastest flight from Greenville to Detroit Metropolitan Wayne County Airport takes 1h 44m
Direct flights go from Greenville to Detroit Metropolitan Wayne County Airport every day.
Search flight deals

Frequently asked questions about flying from Greenville to Detroit Metropolitan Wayne County Airport

  • How far is Greenville to Detroit Metropolitan Wayne County by plane?

    Greenville and Detroit Metropolitan Wayne County are 511.4 mi apart from one another. By plane, this route typically takes 1h 44m.

  • When did momondo last update prices for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from Greenville Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Greenville to Detroit Metropolitan Wayne County Airport?

  • What is the most popular airline from Greenville to Detroit Metropolitan Wayne County Airport?

Best airlines flying from Greenville to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Greenville to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $399Free CancellationRating
7.8
8,491 reviews
Search Delta flights

  • Delta Flights From Greenville to Detroit Metropolitan Wayne County Airport

    The lowest priced Delta flight from Greenville to Detroit Metropolitan Wayne County Airport from the last 72 hours was $399. Generally, Delta has 17 flights on this route every week with an average price of $485. Delta is rated 7.8/10 by our users.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Romulus
Dearborn
Troy
Southfield
Monroe
Livonia
Novi
Roseville
Port Clinton
Sterling Heights
Port Huron
Dundee
Pontiac
Ypsilanti
Belleville
Howell
Farmington Hills

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Detroit?

It is quick and easy to find Greenville to Detroit flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Detroit that suits you.

Can I find flights from Greenville to Detroit with flexible booking policies on momondo?

Flights from Greenville to Detroit with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Greenville to Detroit?

momondo helps you find the best flight between Greenville and Detroit by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to Detroit right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Greenville to Detroit flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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