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Cheap flights from Greenville to Detroit from $103

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Detroit departing on 1/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Greenville to Detroit

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:48 am - 11:59 pm
GSP
-
DTW
14h 11m1 stop
Multiple Airlines Logo
3:10 pm - 8:58 am
DTW
-
GSP
17h 48m1 stop
$198Multiple Airlines
Fri, Jan 9 - Sun, Jan 11
Multiple Airlines Logo
9:48 am - 10:08 pm
GSP
-
DTW
12h 20m2 stops
Multiple Airlines Logo
11:00 am - 8:58 am
DTW
-
GSP
21h 58m2 stops
$212Multiple Airlines
Mon, Jan 12 - Thu, Jan 15
Multiple Airlines Logo
4:07 pm - 1:06 pm
GSP
-
DTW
20h 59m1 stop
Multiple Airlines Logo
9:10 pm - 8:07 pm
DTW
-
GSP
22h 57m1 stop
$218Multiple Airlines
Mon, Jan 12 - Thu, Jan 15
Multiple Airlines Logo
4:07 pm - 1:06 pm
GSP
-
DTW
20h 59m1 stop
Multiple Airlines Logo
2:36 pm - 8:58 am
DTW
-
GSP
18h 22m2 stops
$220Multiple Airlines
Mon, Jan 12 - Thu, Jan 15
Multiple Airlines Logo
9:48 am - 10:08 pm
GSP
-
DTW
12h 20m2 stops
Multiple Airlines Logo
11:00 am - 8:58 am
DTW
-
GSP
21h 58m3 stops
$236Multiple Airlines
Mon, Jan 12 - Thu, Jan 15
Multiple Airlines Logo
4:39 pm - 11:41 pm
GSP
-
DTW
7h 02m1 stop
Multiple Airlines Logo
9:10 pm - 8:07 pm
DTW
-
GSP
22h 57m1 stop
$237Multiple Airlines
Fri, Jan 30 - Sun, Feb 1
Multiple Airlines Logo
9:49 pm - 9:46 am
GSP
-
DTW
11h 57m1 stop
Multiple Airlines Logo
6:35 am - 8:59 pm
DTW
-
GSP
14h 24m1 stop
$238Multiple Airlines
Fri, Jan 16 - Mon, Jan 19
Multiple Airlines Logo
4:39 pm - 10:20 am
GSP
-
DTW
17h 41m2 stops
Multiple Airlines Logo
6:36 pm - 8:58 am
DTW
-
GSP
14h 22m1 stop
$249Multiple Airlines
Fri, Jan 30 - Sun, Feb 1
Multiple Airlines Logo
5:17 pm - 11:40 am
GSP
-
DTW
18h 23m2 stops
Multiple Airlines Logo
6:05 am - 8:07 pm
DTW
-
GSP
14h 02m1 stop
$253Multiple Airlines
Thu, Feb 19 - Mon, Feb 23
Multiple Airlines Logo
4:07 pm - 11:59 pm
GSP
-
DTW
7h 52m2 stops
Multiple Airlines Logo
3:10 pm - 8:58 am
DTW
-
GSP
17h 48m1 stop
$254Multiple Airlines
Fri, Jan 9 - Sun, Jan 11

United Airlines flights from Greenville to Detroit Metropolitan Wayne County Airport

Our best United Airlines deals on Greenville to Detroit Metropolitan Wayne County Airport flight tickets
United Airlines
Dec 18
GSP8:34 amGreenville
10h 30m
2 stops
DTW7:04 pmDetroit Metropolitan Wayne County
Dec 22
DTW5:49 amDetroit Metropolitan Wayne County
5h 07m
1 stop
GSP10:56 amGreenville
$624
Find similar
United Airlines
Dec 12
GSP9:05 amGreenville
10h 11m
2 stops
DTW7:16 pmDetroit Metropolitan Wayne County
Dec 14
DTW5:45 amDetroit Metropolitan Wayne County
11h 08m
2 stops
GSP4:53 pmGreenville
$649
Find similar
United Airlines
Dec 10
GSP9:19 amGreenville
9h 34m
2 stops
DTW6:53 pmDetroit Metropolitan Wayne County
Dec 16
DTW5:45 amDetroit Metropolitan Wayne County
8h 32m
1 stop
GSP2:17 pmGreenville
$668
Find similar

Delta flights from Greenville to Detroit Metropolitan Wayne County Airport

Our best Delta deals on Greenville to Detroit Metropolitan Wayne County Airport flight tickets
Delta
Feb 11
GSP6:05 amGreenville
9h 05m
1 stop
DTW3:10 pmDetroit Metropolitan Wayne County
Feb 18
DTW7:00 amDetroit Metropolitan Wayne County
15h 13m
1 stop
GSP10:13 pmGreenville
$395
Find similar
Delta
Jun 6
GSP7:30 amGreenville
9h 29m
1 stop
DTW4:59 pmDetroit Metropolitan Wayne County
Jun 11
DTW8:40 amDetroit Metropolitan Wayne County
1h 48m
GSP10:28 amGreenville
$397
Find similar
Delta
Jan 16
GSP6:34 pmGreenville
1h 54m
DTW8:28 pmDetroit Metropolitan Wayne County
Jan 19
DTW8:39 pmDetroit Metropolitan Wayne County
1h 45m
GSP10:24 pmGreenville
$399
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from Greenville to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Fri 1/9

9:48 am-11:59 pm

1 stop14h 11m

Detroit Metropolitan Wayne County

Sun 1/11

3:10 pm-8:58 am

1 stop17h 48m

$198

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Mon 1/12

9:48 am-10:08 pm

2 stops12h 20m

Detroit Metropolitan Wayne County

Thu 1/15

11:00 am-8:58 am

2 stops21h 58m

$212

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Mon 1/12

4:07 pm-1:06 pm

1 stop20h 59m

Detroit Metropolitan Wayne County

Thu 1/15

9:10 pm-8:07 pm

1 stop22h 57m

$218

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Mon 1/12

4:07 pm-1:06 pm

1 stop20h 59m

Detroit Metropolitan Wayne County

Thu 1/15

2:36 pm-8:58 am

2 stops18h 22m

$220

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Mon 1/12

9:48 am-10:08 pm

2 stops12h 20m

Detroit Metropolitan Wayne County

Thu 1/15

11:00 am-8:58 am

3 stops21h 58m

$236

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Fri 1/30

4:39 pm-11:41 pm

1 stop7h 02m

Detroit Metropolitan Wayne County

Sun 2/1

9:10 pm-8:07 pm

1 stop22h 57m

$237

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Fri 1/16

9:49 pm-9:46 am

1 stop11h 57m

Detroit Metropolitan Wayne County

Mon 1/19

6:35 am-8:59 pm

1 stop14h 24m

$238

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Fri 1/30

4:39 pm-10:20 am

2 stops17h 41m

Detroit Metropolitan Wayne County

Sun 2/1

6:36 pm-8:58 am

1 stop14h 22m

$249

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Thu 2/19

5:17 pm-11:40 am

2 stops18h 23m

Detroit Metropolitan Wayne County

Mon 2/23

6:05 am-8:07 pm

1 stop14h 02m

$253

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Fri 1/9

4:07 pm-11:59 pm

2 stops7h 52m

Detroit Metropolitan Wayne County

Sun 1/11

3:10 pm-8:58 am

1 stop17h 48m

$254

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Greenville to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Greenville is in May. Flight prices, which tend to average around $366, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of May, then book flights to Detroit Metropolitan Wayne County Airport from Greenville during July instead. Flights to Detroit Metropolitan Wayne County Airport in July, while not as cheap as those in May, still average around $439.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Greenville to Detroit Metropolitan Wayne County Airport is on a Thursday when prices can be found for as low as $427. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Sunday is $682.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Greenville in the morning is the least expensive time of day to depart. momondo users have found prices as low as $455 when looking at flights departing in the morning. Flights to Detroit Metropolitan Wayne County Airport are more costly in the afternoon, with an average ticket price of $649. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Greenville to Detroit Metropolitan Wayne County flight route?

Fly from Greenville to Detroit Metropolitan Wayne County for the best Greenville - Detroit Metropolitan Wayne County flight prices

What cabin class options are available on Greenville to Detroit Metropolitan Wayne County flights?

There are 4 cabin classes available to choose from on Greenville to Detroit Metropolitan Wayne County flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Greenville to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 20% on your flight if you consider stops on a Greenville to Detroit Metropolitan Wayne County Airport flight.

How have Greenville to Detroit Metropolitan Wayne County Airport flight prices changed over time?

As of December 2025, prices for Greenville to Detroit Metropolitan Wayne County Airport flights are approximately 157% more expensive when compared to flights at the same time last year.

When to book flights from Greenville to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Detroit Metropolitan Wayne County Airport (GSP to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Detroit Metropolitan Wayne County Airport

Best Price Found

$248

Fastest flight time

1h 44m

Direct flights

Tue, Wed, Thu, Fri, Sat and Sun
The best one-way flight to Detroit Metropolitan Wayne County Airport from Greenville in the past 72 hours is $248. The best round-trip flight deal from Greenville to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $419.
The fastest flight from Greenville to Detroit Metropolitan Wayne County Airport takes 1h 44m
Direct flights go from Greenville to Detroit Metropolitan Wayne County Airport on Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
Search flight deals

  • How far is Greenville to Detroit Metropolitan Wayne County by plane?

    Greenville and Detroit Metropolitan Wayne County are 511.4 mi apart from one another. By plane, this route typically takes 1h 52m.

  • When did momondo last update prices for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from Greenville Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Greenville to Detroit Metropolitan Wayne County Airport?

  • What is the most popular airline from Greenville to Detroit Metropolitan Wayne County Airport?

Best airlines flying from Greenville to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Greenville to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $243Free CancellationRating
7.9
4,253 reviews
Search Southwest flights
American AirlinesPriceFrom $278Free CancellationRating
7.2
11,048 reviews
Search American Airlines flights
DeltaPriceFrom $397Free CancellationRating
7.9
8,007 reviews
Search Delta flights

  • Delta Flights From Greenville to Detroit Metropolitan Wayne County Airport

    The lowest priced Delta flight from Greenville to Detroit Metropolitan Wayne County Airport from the last 72 hours was $397. Generally, Delta has 19 flights on this route every week with an average price of $498. Delta is rated 7.9/10 by our users.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Troy
Romulus
Dearborn
Southfield
Monroe
Novi
Livonia
Port Clinton
Port Huron
Roseville
Sterling Heights
Brighton
Ypsilanti
Pontiac
Dundee
Madison Heights
Royal Oak

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Detroit?

It is quick and easy to find Greenville to Detroit flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Detroit that suits you.

Can I find flights from Greenville to Detroit with flexible booking policies on momondo?

Flights from Greenville to Detroit with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Greenville to Detroit?

momondo helps you find the best flight between Greenville and Detroit by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to Detroit right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Greenville to Detroit flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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