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Cheap flights from Greenville to Detroit from $145

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Detroit departing on 9/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Greenville to Detroit (GSP-DTW)

Cheap round-trip flights

Logo
3:40 pm - 8:00 amGSP-DTW
16h 20m1 stop
Logo
7:05 am - 8:20 pmDTW-GSP
13h 15m1 stop
$200
Find Deal
vie., oct. 3 - lun., oct. 6
Logo
2:47 pm - 8:00 amGSP-DTW
17h 13m1 stop
Logo
9:39 am - 2:17 pmDTW-GSP
28h 38m2 stops
$272
Find Deal
vie., sep. 12 - dom., sep. 14
Southwest Logo
8:25 am - 12:30 pmGSP-DTW
4h 05m1 stop
Southwest Logo
5:25 am - 9:55 amDTW-GSP
4h 30m1 stop
$293Southwest
Find Deal
jue., oct. 2 - lun., oct. 6
American Airlines Logo
7:20 am - 5:34 pmGSP-DTW
10h 14m1 stop
American Airlines Logo
1:07 pm - 10:11 pmDTW-GSP
9h 04m1 stop
$298American Airlines
Find Deal
sáb., oct. 18 - sáb., oct. 25
Southwest Logo
8:15 am - 12:45 pmGSP-DTW
4h 30m1 stop
Southwest Logo
5:40 am - 10:00 amDTW-GSP
4h 20m1 stop
$318Southwest
Find Deal
vie., oct. 31 - mar., nov. 4
American Airlines Logo
6:05 am - 4:39 pmGSP-DTW
10h 34m1 stop
American Airlines Logo
1:51 pm - 10:45 pmDTW-GSP
8h 54m1 stop
$345American Airlines
Find Deal
mié., sep. 17 - mar., sep. 23
Delta Logo
7:30 am - 9:18 amGSP-DTW
1h 48mnonstop
Delta Logo
7:54 pm - 9:32 pmDTW-GSP
1h 38mnonstop
$419Delta
Find Deal
jue., oct. 9 - lun., oct. 13
United Airlines Logo
9:35 am - 10:28 pmGSP-DTW
12h 53m1 stop
United Airlines Logo
6:05 pm - 9:11 pmDTW-GSP
27h 06m1 stop
$425United Airlines
Find Deal
jue., oct. 2 - lun., oct. 6
Delta Logo
6:29 pm - 8:29 pmGSP-DTW
2h 00mnonstop
Delta Logo
9:30 pm - 10:18 amDTW-GSP
12h 48m1 stop
$427Delta
Find Deal
mié., dic. 17 - jue., ene. 1
United Airlines Logo
9:35 am - 11:41 pmGSP-DTW
14h 06m1 stop
United Airlines Logo
6:05 pm - 2:11 pmDTW-GSP
20h 06m2 stops
$430United Airlines
Find Deal
jue., oct. 2 - lun., oct. 6

Southwest flights from Greenville to Detroit Metropolitan Wayne County Airport

Our best Southwest deals on Greenville to Detroit Metropolitan Wayne County Airport flight tickets
Southwest
Oct 2
GSP8:25 amGreenville
4h 05m
1 stop
DTW12:30 pmDetroit Metropolitan Wayne County
Oct 6
DTW5:25 amDetroit Metropolitan Wayne County
4h 30m
1 stop
GSP9:55 amGreenville
$293
Find similar
Southwest
Oct 31
GSP8:15 amGreenville
4h 30m
1 stop
DTW12:45 pmDetroit Metropolitan Wayne County
Nov 4
DTW5:40 amDetroit Metropolitan Wayne County
4h 20m
1 stop
GSP10:00 amGreenville
$318
Find similar
Southwest
Oct 31
GSP8:15 amGreenville
4h 30m
1 stop
DTW12:45 pmDetroit Metropolitan Wayne County
Nov 4
DTW5:40 amDetroit Metropolitan Wayne County
10h 25m
2 stops
GSP4:05 pmGreenville
$323
Find similar

American Airlines flights from Greenville to Detroit Metropolitan Wayne County Airport

Our best American Airlines deals on Greenville to Detroit Metropolitan Wayne County Airport flight tickets
American Airlines
Oct 18
GSP7:20 amGreenville
10h 14m
1 stop
DTW5:34 pmDetroit Metropolitan Wayne County
Oct 25
DTW1:07 pmDetroit Metropolitan Wayne County
9h 04m
1 stop
GSP10:11 pmGreenville
$298
Find similar
American Airlines
Sep 17
GSP6:05 amGreenville
10h 34m
1 stop
DTW4:39 pmDetroit Metropolitan Wayne County
Sep 23
DTW1:51 pmDetroit Metropolitan Wayne County
8h 54m
1 stop
GSP10:45 pmGreenville
$345
Find similar
American Airlines
Oct 18
GSP8:25 amGreenville
8h 49m
1 stop
DTW5:14 pmDetroit Metropolitan Wayne County
Oct 21
DTW1:11 pmDetroit Metropolitan Wayne County
8h 39m
1 stop
GSP9:50 pmGreenville
$346
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 3, 2025.
Use the filters below to find and compare flights from Greenville to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

vie. 10/3

3:40 pm-8:00 am

1 stop16h 20m

Detroit Metropolitan Wayne County

lun. 10/6

7:05 am-8:20 pm

1 stop13h 15m

$200

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

vie. 9/12

2:47 pm-8:00 am

1 stop17h 13m

Detroit Metropolitan Wayne County

dom. 9/14

9:39 am-2:17 pm

2 stops28h 38m

$272

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

jue. 10/2

8:25 am-12:30 pm

1 stop4h 05m

Detroit Metropolitan Wayne County

lun. 10/6

5:25 am-9:55 am

1 stop4h 30m

$293

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

sáb. 10/18

7:20 am-5:34 pm

1 stop10h 14m

Detroit Metropolitan Wayne County

sáb. 10/25

1:07 pm-10:11 pm

1 stop9h 04m

$298

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

vie. 10/31

8:15 am-12:45 pm

1 stop4h 30m

Detroit Metropolitan Wayne County

mar. 11/4

5:40 am-10:00 am

1 stop4h 20m

$318

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

mié. 9/17

6:05 am-4:39 pm

1 stop10h 34m

Detroit Metropolitan Wayne County

mar. 9/23

1:51 pm-10:45 pm

1 stop8h 54m

$345

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

jue. 10/9

7:30 am-9:18 am

Nonstop1h 48m

Detroit Metropolitan Wayne County

lun. 10/13

7:54 pm-9:32 pm

Nonstop1h 38m

$419

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

jue. 10/2

9:35 am-10:28 pm

1 stop12h 53m

Detroit Metropolitan Wayne County

lun. 10/6

6:05 pm-9:11 pm

1 stop27h 06m

$425

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

mié. 12/17

6:29 pm-8:29 pm

Nonstop2h 00m

Detroit Metropolitan Wayne County

jue. 1/1

9:30 pm-10:18 am

1 stop12h 48m

$427

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

jue. 10/2

9:35 am-11:41 pm

1 stop14h 06m

Detroit Metropolitan Wayne County

lun. 10/6

6:05 pm-2:11 pm

2 stops20h 06m

$430

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Greenville to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Greenville is in May. Flight prices, which tend to average around $366, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of May, then book flights to Detroit Metropolitan Wayne County Airport from Greenville during July instead. Flights to Detroit Metropolitan Wayne County Airport in July, while not as cheap as those in May, still average around $439.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Greenville to Detroit Metropolitan Wayne County Airport is on a Saturday when prices can be found for as low as $418. Be sure to avoid booking your departure on a Wednesday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Wednesday is $728.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Greenville in the morning is the least expensive time of day to depart. momondo users have found prices as low as $480 when looking at flights departing in the morning. Flights to Detroit Metropolitan Wayne County Airport are more costly in the afternoon, with an average ticket price of $734. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Greenville to Detroit Metropolitan Wayne County flight route?

Fly from Greenville to Detroit Metropolitan Wayne County for the best Greenville - Detroit Metropolitan Wayne County flight prices

How far in advance should I book a flight to Detroit Metropolitan Wayne County Airport?

You are more likely to see cheaper flights to Detroit Metropolitan Wayne County Airport from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to Detroit Metropolitan Wayne County Airport for around $505 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Detroit Metropolitan Wayne County Airport from Greenville for as low as $278 on momondo.

What cabin class options are available on Greenville to Detroit Metropolitan Wayne County flights?

There are 4 cabin classes available to choose from on Greenville to Detroit Metropolitan Wayne County flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Greenville to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 59% on your flight if you consider stops on a Greenville to Detroit Metropolitan Wayne County Airport flight.

How have Greenville to Detroit Metropolitan Wayne County Airport flight prices changed over time?

As of September 2025, prices for Greenville to Detroit Metropolitan Wayne County Airport flights are approximately 25% more expensive when compared to flights at the same time last year.

When to book flights from Greenville to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Detroit Metropolitan Wayne County Airport (GSP to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Detroit Metropolitan Wayne County Airport

Best Price Found

$196

Fastest flight time

1h 45m

Direct flights

Every day
The best one-way flight to Detroit Metropolitan Wayne County Airport from Greenville in the past 72 hours is $196. The best round-trip flight deal from Greenville to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $288.
The fastest flight from Greenville to Detroit Metropolitan Wayne County Airport takes 1h 45m
Direct flights go from Greenville to Detroit Metropolitan Wayne County Airport every day.
Search flight deals

  • How far is Greenville to Detroit Metropolitan Wayne County by plane?

    Greenville and Detroit Metropolitan Wayne County are 511.4 mi apart from one another. By plane, this route typically takes 1h 48m.

  • When did momondo last update prices for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from Greenville Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Greenville to Detroit Metropolitan Wayne County Airport?

  • What is the most popular airline from Greenville to Detroit Metropolitan Wayne County Airport?

Best airlines flying from Greenville to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Greenville to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $278Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $312Free CancellationRating
8.0
4,238 reviews
Search Southwest flights
DeltaPriceFrom $369Free CancellationRating
7.9
7,973 reviews
Search Delta flights

  • Delta Flights From Greenville to Detroit Metropolitan Wayne County Airport

    The lowest priced Delta flight from Greenville to Detroit Metropolitan Wayne County Airport from the last 72 hours was $369. Generally, Delta has 12 flights on this route every week with an average price of $528. Delta is rated 7.9/10 by our users.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Monroe
Southfield
Troy
Novi
Dearborn
Romulus
Livonia
Port Huron
Port Clinton
Sterling Heights
Roseville
Brighton
Ypsilanti
Madison Heights
Pontiac
Belleville
Farmington Hills

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Detroit?

It is quick and easy to find Greenville to Detroit flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Detroit that suits you.

Can I find flights from Greenville to Detroit with flexible booking policies on momondo?

Flights from Greenville to Detroit with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Greenville to Detroit?

momondo helps you find the best flight between Greenville and Detroit by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to Detroit right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Greenville to Detroit flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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