What is the cheapest airline that flies from Greenville to Detroit Metropolitan Wayne County?

American Airlines, Southwest, and Delta are the most popular carriers operating from Greenville to Detroit Metropolitan Wayne County

What airlines fly to Detroit Metropolitan Wayne County Airport?

American Airlines, Delta and Spirit Airlines are the top three most popular airlines that fly to Detroit Metropolitan Wayne County Airport from Greenville according to our data. American Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to Detroit Metropolitan Wayne County Airport. Keep in mind that there are 5 different airlines that fly to Detroit Metropolitan Wayne County Airport on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?

Prices for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport were last updated today.

How many operators does momondo search for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?

The number of operators available for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport is 3 as of October 2025.

How old do you have to be to fly from Greenville Airport to Detroit Metropolitan Wayne County Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Detroit Metropolitan Wayne County Airport.

What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$103 Cheap Flights from Greenville to Detroit Metropolitan Wayne County Airport in 2025/26

Q: How many flights depart from Greenville to Detroit Metropolitan Wayne County Airport on average per day?

11 flights are operational daily from Greenville to Detroit Metropolitan Wayne County Airport as of October 2025. The most popular departure time for this route is 11:00AM, with 70% of flights per day taking off at noon.

Q: How many flights depart from Greenville to Detroit Metropolitan Wayne County Airport on average per week?

The number of flights available between Greenville and Detroit Metropolitan Wayne County Airport is 80 per week as of October 2025. The most frequent departure day is Mon, with 15% of weekly flights leaving on this day.

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8:03 pm - 8:20 amGSP-DTW

12h 17m1 stop

8:30 pm - 7:23 pmDTW-GSP

22h 53m1 stop

$192Multiple Airlines

Find Deal

Fri, Dec 5 - Sun, Dec 7

4:00 pm - 8:20 amGSP-DTW

16h 20m1 stop

5:58 pm - 8:49 pmDTW-GSP

26h 51m1 stop

$209Multiple Airlines

Find Deal

Thu, Dec 4 - Sun, Dec 7

4:00 pm - 8:20 amGSP-DTW

16h 20m1 stop

5:58 pm - 8:49 pmDTW-GSP

26h 51m1 stop

$216Multiple Airlines

Find Deal

Thu, Dec 4 - Sun, Dec 14

9:34 pm - 10:17 amGSP-DTW

12h 43m1 stop

5:20 am - 3:42 pmDTW-GSP

10h 22m1 stop

$238Multiple Airlines

Find Deal

Sat, Nov 22 - Thu, Nov 27

8:03 pm - 11:42 amGSP-DTW

15h 39m1 stop

6:15 am - 9:14 pmDTW-GSP

14h 59m1 stop

$240Multiple Airlines

Find Deal

Fri, Dec 5 - Sun, Dec 7

4:45 pm - 10:35 pmGSP-DTW

5h 50m1 stop

5:25 am - 10:40 amDTW-GSP

5h 15m1 stop

$270Southwest

Find Deal

Wed, Dec 31 - Wed, Jan 7

7:47 am - 6:15 pmGSP-DTW

10h 28m1 stop

7:00 am - 6:22 pmDTW-GSP

11h 22m1 stop

$345American Airlines

Find Deal

Sat, Nov 15 - Sat, Nov 22

7:45 am - 2:52 pmGSP-DTW

7h 07m1 stop

5:33 am - 4:25 pmDTW-GSP

10h 52m1 stop

$354American Airlines

Find Deal

Sat, Nov 22 - Thu, Nov 27

8:10 am - 3:00 pmGSP-DTW

6h 50m1 stop

5:40 am - 10:00 amDTW-GSP

4h 20m1 stop

$355Southwest

Find Deal

Sat, Dec 6 - Mon, Dec 8

8:10 am - 3:00 pmGSP-DTW

6h 50m1 stop

5:40 am - 4:05 pmDTW-GSP

10h 25m2 stops

$360Southwest

Find Deal

Sat, Dec 6 - Mon, Dec 8

Southwest flights from Greenville to Detroit Metropolitan Wayne County Airport

Our best Southwest deals on Greenville to Detroit Metropolitan Wayne County Airport flight tickets

Southwest

Dec 31

GSP4:45 pmGreenville

5h 50m

1 stop

DTW10:35 pmDetroit Metropolitan Wayne County

Jan 7

DTW5:25 amDetroit Metropolitan Wayne County

5h 15m

1 stop

GSP10:40 amGreenville

$270

Find similar

Southwest

Dec 6

GSP8:10 amGreenville

6h 50m

1 stop

DTW3:00 pmDetroit Metropolitan Wayne County

Dec 8

DTW5:40 amDetroit Metropolitan Wayne County

4h 20m

1 stop

GSP10:00 amGreenville

$355

Find similar

Southwest

Dec 6

GSP8:10 amGreenville

6h 50m

1 stop

DTW3:00 pmDetroit Metropolitan Wayne County

Dec 8

DTW5:40 amDetroit Metropolitan Wayne County

10h 25m

2 stops

GSP4:05 pmGreenville

$360

Find similar

American Airlines flights from Greenville to Detroit Metropolitan Wayne County Airport

Our best American Airlines deals on Greenville to Detroit Metropolitan Wayne County Airport flight tickets

American Airlines

Nov 15

GSP7:47 amGreenville

10h 28m

1 stop

DTW6:15 pmDetroit Metropolitan Wayne County

Nov 22

DTW7:00 amDetroit Metropolitan Wayne County

11h 22m

1 stop

GSP6:22 pmGreenville

$345

Find similar

American Airlines

Nov 22

GSP7:45 amGreenville

7h 07m

1 stop

DTW2:52 pmDetroit Metropolitan Wayne County

Nov 27

DTW5:33 amDetroit Metropolitan Wayne County

10h 52m

1 stop

GSP4:25 pmGreenville

$354

Find similar

American Airlines

Nov 1

GSP8:50 amGreenville

6h 37m

2 stops

DTW3:27 pmDetroit Metropolitan Wayne County

Nov 9

DTW6:01 amDetroit Metropolitan Wayne County

4h 02m

1 stop

GSP10:03 amGreenville

$494

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Greenville to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Fri 12/5

8:03 pm-8:20 am

1 stop12h 17m

Detroit Metropolitan Wayne County

Sun 12/7

8:30 pm-7:23 pm

1 stop22h 53m

$192

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Thu 12/4

4:00 pm-8:20 am

1 stop16h 20m

Detroit Metropolitan Wayne County

Sun 12/7

5:58 pm-8:49 pm

1 stop26h 51m

$209

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Thu 12/4

4:00 pm-8:20 am

1 stop16h 20m

Detroit Metropolitan Wayne County

Sun 12/14

5:58 pm-8:49 pm

1 stop26h 51m

$216

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Sat 11/22

9:34 pm-10:17 am

1 stop12h 43m

Detroit Metropolitan Wayne County

Thu 11/27

5:20 am-3:42 pm

1 stop10h 22m

$238

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Fri 12/5

8:03 pm-11:42 am

1 stop15h 39m

Detroit Metropolitan Wayne County

Sun 12/7

6:15 am-9:14 pm

1 stop14h 59m

$240

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Wed 12/31

4:45 pm-10:35 pm

1 stop5h 50m

Detroit Metropolitan Wayne County

Wed 1/7

5:25 am-10:40 am

1 stop5h 15m

$270

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Sat 11/15

7:47 am-6:15 pm

1 stop10h 28m

Detroit Metropolitan Wayne County

Sat 11/22

7:00 am-6:22 pm

1 stop11h 22m

$345

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Sat 11/22

7:45 am-2:52 pm

1 stop7h 07m

Detroit Metropolitan Wayne County

Thu 11/27

5:33 am-4:25 pm

1 stop10h 52m

$354

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Sat 12/6

8:10 am-3:00 pm

1 stop6h 50m

Detroit Metropolitan Wayne County

Mon 12/8

5:40 am-10:00 am

1 stop4h 20m

$355

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Sat 12/6

8:10 am-3:00 pm

1 stop6h 50m

Detroit Metropolitan Wayne County

Mon 12/8

5:40 am-4:05 pm

2 stops10h 25m

$360

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Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Greenville to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Greenville is in May. Flight prices, which tend to average around $366, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of May, then book flights to Detroit Metropolitan Wayne County Airport from Greenville during July instead. Flights to Detroit Metropolitan Wayne County Airport in July, while not as cheap as those in May, still average around $439.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Greenville to Detroit Metropolitan Wayne County Airport is on a Saturday when prices can be found for as low as $433. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Sunday is $734.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Greenville in the morning is the least expensive time of day to depart. momondo users have found prices as low as $466 when looking at flights departing in the morning. Flights to Detroit Metropolitan Wayne County Airport are more costly in the afternoon, with an average ticket price of $733. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Greenville to Detroit Metropolitan Wayne County flight route?

Fly from Greenville to Detroit Metropolitan Wayne County for the best Greenville - Detroit Metropolitan Wayne County flight prices

What cabin class options are available on Greenville to Detroit Metropolitan Wayne County flights?

There are 4 cabin classes available to choose from on Greenville to Detroit Metropolitan Wayne County flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Greenville to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 57% on your flight if you consider stops on a Greenville to Detroit Metropolitan Wayne County Airport flight.

How have Greenville to Detroit Metropolitan Wayne County Airport flight prices changed over time?

As of October 2025, prices for Greenville to Detroit Metropolitan Wayne County Airport flights are approximately 159% more expensive when compared to flights at the same time last year.

When to book flights from Greenville to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Greenville to Detroit Metropolitan Wayne County Airport (GSP to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Detroit Metropolitan Wayne County Airport

Best Price Found	$258
Fastest flight time	1h 47m
Direct flights	Every day

The best one-way flight to Detroit Metropolitan Wayne County Airport from Greenville in the past 72 hours is $258. The best round-trip flight deal from Greenville to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $358.

The fastest flight from Greenville to Detroit Metropolitan Wayne County Airport takes 1h 47m

Direct flights go from Greenville to Detroit Metropolitan Wayne County Airport every day.

Search flight deals

How far is Greenville to Detroit Metropolitan Wayne County by plane?
Greenville and Detroit Metropolitan Wayne County are 511.4 mi apart from one another. By plane, this route typically takes 5h 50m.
When did momondo last update prices for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?
Prices for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport were last updated today.
How many operators does momondo search for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?
The number of operators available for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport is 3 as of October 2025.
How old do you have to be to fly from Greenville Airport to Detroit Metropolitan Wayne County Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Detroit Metropolitan Wayne County Airport.
What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?
The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Greenville to Detroit Metropolitan Wayne County Airport?
momondo data reveals that the most frequently booked plane model on the route from Greenville to Detroit Metropolitan Wayne County Airport is Boeing 717-200, representing 34.55% of all bookings. The subsequent popular models are Canadair (Bombardier) Regional Jet 900 at 30.91%, Canadair (Bombardier) Regional Jet 700 at 12.12%, and Embraer 175 (Enhanced Winglets) at 3.64%.
What is the most popular airline from Greenville to Detroit Metropolitan Wayne County Airport?
Based on momondo bookings for flights between Greenville and Detroit Metropolitan Wayne County Airport, the leading airline is Delta, making up 85% of the total bookings. Other popular airlines include American Airlines with 8% and Southwest with 7%.

Best airlines flying from Greenville to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Greenville to Detroit Metropolitan Wayne County Airport with momondo

Airline	Rating	Free Cancellation	Price
Southwest	PriceFrom $243	Free Cancellation	Rating 8.0 4,239 reviews	Search Southwest flights
American Airlines	PriceFrom $278	Free Cancellation	Rating 7.2 11,024 reviews	Search American Airlines flights
Delta	PriceFrom $397	Free Cancellation	Rating 7.9 7,978 reviews	Search Delta flights

Delta Flights From Greenville to Detroit Metropolitan Wayne County Airport
The lowest priced Delta flight from Greenville to Detroit Metropolitan Wayne County Airport from the last 72 hours was $397. Generally, Delta has 20 flights on this route every week with an average price of $507. Delta is rated 7.9/10 by our users.

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Sterling Heights

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Brighton

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Pontiac

Madison Heights

Dundee

Royal Oak

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Detroit?

It is quick and easy to find Greenville to Detroit flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Detroit that suits you.

Can I find flights from Greenville to Detroit with flexible booking policies on momondo?

Flights from Greenville to Detroit with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Greenville to Detroit?

momondo helps you find the best flight between Greenville and Detroit by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to Detroit right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Greenville to Detroit flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Detroit Metropolitan Wayne County Airport trip

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Detroit Metropolitan Wayne County Airport flight routes

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Cheap flights from Greenville to Detroit from $103

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Detroit departing on 12/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Southwest flights from Greenville to Detroit Metropolitan Wayne County Airport

Our best Southwest deals on Greenville to Detroit Metropolitan Wayne County Airport flight tickets

American Airlines flights from Greenville to Detroit Metropolitan Wayne County Airport

Our best American Airlines deals on Greenville to Detroit Metropolitan Wayne County Airport flight tickets

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Use the filters below to find and compare flights from Greenville to Detroit Metropolitan Wayne County Airport that are best for you.

See travel insights to Detroit from

How to get the cheapest flight ticket from Greenville to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

What is the cheapest Greenville to Detroit Metropolitan Wayne County flight route?

Fly from Greenville to Detroit Metropolitan Wayne County for the best Greenville - Detroit Metropolitan Wayne County flight prices

What cabin class options are available on Greenville to Detroit Metropolitan Wayne County flights?

There are 4 cabin classes available to choose from on Greenville to Detroit Metropolitan Wayne County flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Greenville to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 57% on your flight if you consider stops on a Greenville to Detroit Metropolitan Wayne County Airport flight.

How have Greenville to Detroit Metropolitan Wayne County Airport flight prices changed over time?

As of October 2025, prices for Greenville to Detroit Metropolitan Wayne County Airport flights are approximately 159% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Greenville to Detroit Metropolitan Wayne County?

American Airlines, Southwest, and Delta are the most popular carriers operating from Greenville to Detroit Metropolitan Wayne County

What airlines fly to Detroit Metropolitan Wayne County Airport?

How many flights depart from Greenville to Detroit Metropolitan Wayne County Airport on average per day?

11 flights are operational daily from Greenville to Detroit Metropolitan Wayne County Airport as of October 2025. The most popular departure time for this route is 11:00AM, with 70% of flights per day taking off at noon.

How many flights depart from Greenville to Detroit Metropolitan Wayne County Airport on average per week?

The number of flights available between Greenville and Detroit Metropolitan Wayne County Airport is 80 per week as of October 2025. The most frequent departure day is Mon, with 15% of weekly flights leaving on this day.

When to book flights from Greenville to Detroit Metropolitan Wayne County Airport

Cheap Greenville to Detroit Metropolitan Wayne County Airport (GSP to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Detroit Metropolitan Wayne County Airport

Best Price Found

Fastest flight time

Direct flights

How far is Greenville to Detroit Metropolitan Wayne County by plane?

When did momondo last update prices for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?

How many operators does momondo search for flights from Greenville Airport to Detroit Metropolitan Wayne County Airport?

How old do you have to be to fly from Greenville Airport to Detroit Metropolitan Wayne County Airport?

What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

What is the most popular plane model from Greenville to Detroit Metropolitan Wayne County Airport?

What is the most popular airline from Greenville to Detroit Metropolitan Wayne County Airport?

Best airlines flying from Greenville to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Greenville to Detroit Metropolitan Wayne County Airport with momondo

Delta Flights From Greenville to Detroit Metropolitan Wayne County Airport

Traveling to a place near Detroit?

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Detroit?

Can I find flights from Greenville to Detroit with flexible booking policies on momondo?

How can momondo help me find flights from Greenville to Detroit?

I’m not ready to book a flight from Greenville to Detroit right now. Can momondo alert me if prices change?

An easier way to manage your Detroit Metropolitan Wayne County Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Detroit

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo