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Cheap flights from Florida to Florence from $362

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Florida to Florence departing on 11/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Florida to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:33 pm - 10:53 pmMIA-FLO
5h 20m1 stop
American Airlines Logo
10:28 am - 3:22 pmFLO-MIA
4h 54m1 stop
$403American Airlines
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Wed, Dec 3 - Wed, Dec 10
American Airlines Logo
6:29 am - 10:02 amMCO-FLO
3h 33m1 stop
American Airlines Logo
11:13 am - 4:17 pmFLO-MCO
5h 04m1 stop
$411American Airlines
Find Deal
Fri, Apr 24 - Sat, May 2
American Airlines Logo
8:02 pm - 11:41 pmMCO-FLO
3h 39m1 stop
American Airlines Logo
2:33 pm - 10:10 pmFLO-MCO
7h 37m2 stops
$416American Airlines
Find Deal
Fri, Apr 24 - Sat, May 2
American Airlines Logo
6:36 pm - 10:53 pmSRQ-FLO
4h 17m1 stop
American Airlines Logo
6:15 am - 12:30 pmFLO-SRQ
6h 15m1 stop
$417American Airlines
Find Deal
Tue, Dec 2 - Tue, Dec 9
American Airlines Logo
1:15 pm - 10:53 pmMIA-FLO
9h 38m2 stops
American Airlines Logo
10:28 am - 5:40 pmFLO-MIA
7h 12m1 stop
$435American Airlines
Find Deal
Wed, Dec 3 - Wed, Dec 10
American Airlines Logo
8:02 pm - 11:38 pmSRQ-FLO
3h 36m1 stop
American Airlines Logo
11:09 am - 6:09 pmFLO-SRQ
7h 00m1 stop
$467American Airlines
Find Deal
Tue, Mar 24 - Sat, Mar 28
American Airlines Logo
8:37 am - 2:05 pmMCO-FLO
5h 28m1 stop
American Airlines Logo
5:13 am - 9:52 amFLO-MCO
4h 39m1 stop
$467American Airlines
Find Deal
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
6:30 am - 2:05 pmSRQ-FLO
7h 35m2 stops
American Airlines Logo
5:13 am - 10:50 amFLO-SRQ
5h 37m1 stop
$472American Airlines
Find Deal
Tue, Mar 24 - Sat, Mar 28
American Airlines Logo
1:33 pm - 11:38 pmMCO-FLO
10h 05m2 stops
American Airlines Logo
2:30 pm - 6:01 pmFLO-MCO
3h 31m1 stop
$472American Airlines
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Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
8:27 am - 2:05 pmRSW-FLO
5h 38m1 stop
American Airlines Logo
5:13 am - 9:11 amFLO-RSW
3h 58m1 stop
$475American Airlines
Find Deal
Thu, Mar 26 - Sun, Mar 29

American Airlines flights from Florida to Florence, South Carolina

Our best American Airlines deals on Florida to Florence, South Carolina flight tickets
American Airlines
Dec 3
MIA5:33 pmMiami
5h 20m
1 stop
FLO10:53 pmFlorence
Dec 10
FLO10:28 amFlorence
4h 54m
1 stop
MIA3:22 pmMiami
$403
Find similar
American Airlines
Apr 24
MCO6:29 amOrlando
3h 33m
1 stop
FLO10:02 amFlorence
May 2
FLO11:13 amFlorence
5h 04m
1 stop
MCO4:17 pmOrlando
$411
Find similar
American Airlines
Apr 24
MCO8:02 pmOrlando
3h 39m
1 stop
FLO11:41 pmFlorence
May 2
FLO2:33 pmFlorence
7h 37m
2 stops
MCO10:10 pmOrlando
$416
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Florida to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Florida to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MiamiFlorence

MIA - FLO

MIAFLO

Miami

Wed 12/3

5:33 pm-10:53 pm

1 stop5h 20m

Florence

Wed 12/10

10:28 am-3:22 pm

1 stop4h 54m

$403

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Fri 4/24

6:29 am-10:02 am

1 stop3h 33m

Florence

Sat 5/2

11:13 am-4:17 pm

1 stop5h 04m

$411

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Fri 4/24

8:02 pm-11:41 pm

1 stop3h 39m

Florence

Sat 5/2

2:33 pm-10:10 pm

2 stops7h 37m

$416

SarasotaFlorence

SRQ - FLO

SRQFLO

Sarasota Bradenton Intl

Tue 12/2

6:36 pm-10:53 pm

1 stop4h 17m

Florence

Tue 12/9

6:15 am-12:30 pm

1 stop6h 15m

$417

MiamiFlorence

MIA - FLO

MIAFLO

Miami

Wed 12/3

1:15 pm-10:53 pm

2 stops9h 38m

Florence

Wed 12/10

10:28 am-5:40 pm

1 stop7h 12m

$435

SarasotaFlorence

SRQ - FLO

SRQFLO

Sarasota Bradenton Intl

Tue 3/24

8:02 pm-11:38 pm

1 stop3h 36m

Florence

Sat 3/28

11:09 am-6:09 pm

1 stop7h 00m

$467

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Wed 3/25

8:37 am-2:05 pm

1 stop5h 28m

Florence

Sat 3/28

5:13 am-9:52 am

1 stop4h 39m

$467

SarasotaFlorence

SRQ - FLO

SRQFLO

Sarasota Bradenton Intl

Tue 3/24

6:30 am-2:05 pm

2 stops7h 35m

Florence

Sat 3/28

5:13 am-10:50 am

1 stop5h 37m

$472

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Wed 3/25

1:33 pm-11:38 pm

2 stops10h 05m

Florence

Sat 3/28

2:30 pm-6:01 pm

1 stop3h 31m

$472

Fort MyersFlorence

RSW - FLO

RSWFLO

Fort Myers SW Florida Intl

Thu 3/26

8:27 am-2:05 pm

1 stop5h 38m

Florence

Sun 3/29

5:13 am-9:11 am

1 stop3h 58m

$475

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Florida to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence, South Carolina?

On average, the least expensive day to fly to Florence, South Carolina from Florida is on a Monday. momondo users have found tickets for Monday departures for as low as $516. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Saturday is the most expensive day to depart from Florida because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $630.

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is in the evening. momondo users have found flights departing from Florida to Florence, South Carolina in the evening for as low as $464. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $582 per ticket.

Cheap Florida to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florida to Florence, South Carolina

Direct flights

None
There are no direct flights from Florida to Florence, South Carolina. There are no popular flight routes from Florida to Florence, South Carolina.
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  • When did momondo last update prices for flights from Florida to Florence Airport?

    Prices for flights from Florida to Florence Airport were last updated today.

  • How many operators does momondo search for flights from Florida to Florence Airport?

  • How old do you have to be to fly from Florida to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Florida to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Florida to Florence, South Carolina

Compare and see reviews for airlines that fly from Florida to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $371Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Florida to Florence?

Finding the right flight to Florence from Florida is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florence quick and easy, saving you time and money.

Can I find flights from Florida to Florence with flexible booking policies on momondo?

All flight searches from Florida to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Florida to Florence?

momondo helps you find the best flight between Florida and Florence by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Florida to Florence right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Florence, momondo offers a useful price alert feature which will track prices for flights to Florence from Florida and alert you when they change.

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