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Cheap flights from Florida to Florence from $372

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Florida to Florence departing on 11/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Florida to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
4:21 pm - 10:59 pm
MCO
-
FLO
6h 38m
1 stop
American Airlines Logo
3:22 pm - 9:04 pm
FLO
-
MCO
5h 42m
1 stop
$447American Airlines
Tue, Sep 1 - Tue, Sep 8
American Airlines Logo
6:51 pm - 11:57 pm
TPA
-
FLO
5h 06m
1 stop
American Airlines Logo
2:34 pm - 8:27 pm
FLO
-
TPA
5h 53m
1 stop
$447American Airlines
Wed, Oct 14 - Wed, Oct 21
American Airlines Logo
7:57 am - 2:10 pm
MIA
-
FLO
6h 13m
1 stop
American Airlines Logo
3:22 pm - 8:13 pm
FLO
-
MIA
4h 51m
1 stop
$463American Airlines
Tue, Aug 4 - Tue, Aug 11
American Airlines Logo
7:44 am - 2:10 pm
FLL
-
FLO
6h 26m
1 stop
American Airlines Logo
6:22 am - 10:18 am
FLO
-
FLL
3h 56m
1 stop
$477American Airlines
Sat, Aug 1 - Sat, Aug 8
American Airlines Logo
10:12 am - 2:10 pm
TPA
-
FLO
3h 58m
1 stop
American Airlines Logo
2:35 pm - 9:23 pm
FLO
-
TPA
6h 48m
1 stop
$507American Airlines
Tue, Jul 21 - Sat, Jul 25
American Airlines Logo
1:55 pm - 6:07 pm
MCO
-
FLO
4h 12m
1 stop
American Airlines Logo
5:15 am - 5:12 pm
FLO
-
MCO
11h 57m
2 stops
$510American Airlines
Wed, Nov 4 - Sat, Nov 14
American Airlines Logo
11:25 am - 6:07 pm
MIA
-
FLO
6h 42m
1 stop
American Airlines Logo
5:15 am - 9:09 am
FLO
-
MIA
3h 54m
1 stop
$511American Airlines
Wed, Nov 18 - Thu, Nov 26
American Airlines Logo
5:36 pm - 10:59 pm
MCO
-
FLO
5h 23m
1 stop
American Airlines Logo
6:22 am - 12:31 pm
FLO
-
MCO
6h 09m
1 stop
$515American Airlines
Thu, Aug 6 - Mon, Aug 10
American Airlines Logo
9:30 am - 2:56 pm
TPA
-
FLO
5h 26m
1 stop
American Airlines Logo
3:22 pm - 9:21 pm
FLO
-
TPA
5h 59m
1 stop
$515American Airlines
Thu, Aug 6 - Thu, Aug 13
American Airlines Logo
10:12 am - 2:10 pm
TPA
-
FLO
3h 58m
1 stop
American Airlines Logo
3:22 pm - 7:57 pm
FLO
-
TPA
4h 35m
1 stop
$522American Airlines
Sun, Aug 2 - Sat, Aug 8

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American Airlines flights from Florida to Florence, South Carolina

Our best American Airlines deals on Florida to Florence, South Carolina flight tickets
American Airlines
Sep 1
MCO4:21 pmOrlando
6h 38m
1 stop
FLO10:59 pmFlorence
Sep 8
FLO3:22 pmFlorence
5h 42m
1 stop
MCO9:04 pmOrlando
$447
American Airlines
Aug 4
MIA7:57 amMiami
6h 13m
1 stop
FLO2:10 pmFlorence
Aug 11
FLO3:22 pmFlorence
4h 51m
1 stop
MIA8:13 pmMiami
$463
American Airlines
Aug 1
FLL7:44 amFort Lauderdale
6h 26m
1 stop
FLO2:10 pmFlorence
Aug 8
FLO6:22 amFlorence
3h 56m
1 stop
FLL10:18 amFort Lauderdale
$477

momondo Fare Finder

 
Customize your flight search to find flights from Florida to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 9, 2026.
Use the filters below to find and compare flights from Florida to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Tue 9/1

4:21 pm-10:59 pm

1 stop6h 38m

Florence

Tue 9/8

3:22 pm-9:04 pm

1 stop5h 42m

$447

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Wed 10/14

6:51 pm-11:57 pm

1 stop5h 06m

Florence

Wed 10/21

2:34 pm-8:27 pm

1 stop5h 53m

$447

MiamiFlorence

MIA - FLO

MIAFLO

Miami

Tue 8/4

7:57 am-2:10 pm

1 stop6h 13m

Florence

Tue 8/11

3:22 pm-8:13 pm

1 stop4h 51m

$463

Fort LauderdaleFlorence

FLL - FLO

FLLFLO

Fort Lauderdale

Sat 8/1

7:44 am-2:10 pm

1 stop6h 26m

Florence

Sat 8/8

6:22 am-10:18 am

1 stop3h 56m

$477

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Tue 7/21

10:12 am-2:10 pm

1 stop3h 58m

Florence

Sat 7/25

2:35 pm-9:23 pm

1 stop6h 48m

$507

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Wed 11/4

1:55 pm-6:07 pm

1 stop4h 12m

Florence

Sat 11/14

5:15 am-5:12 pm

2 stops11h 57m

$510

MiamiFlorence

MIA - FLO

MIAFLO

Miami

Wed 11/18

11:25 am-6:07 pm

1 stop6h 42m

Florence

Thu 11/26

5:15 am-9:09 am

1 stop3h 54m

$511

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Thu 8/6

5:36 pm-10:59 pm

1 stop5h 23m

Florence

Mon 8/10

6:22 am-12:31 pm

1 stop6h 09m

$515

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Thu 8/6

9:30 am-2:56 pm

1 stop5h 26m

Florence

Thu 8/13

3:22 pm-9:21 pm

1 stop5h 59m

$515
Quickest round-trip

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Sun 8/2

10:12 am-2:10 pm

1 stop3h 58m

Florence

Sat 8/8

3:22 pm-7:57 pm

1 stop4h 35m

$522

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Florida to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Florida to Florence, South Carolina flights?

You could potentially save up to 59% on your flight if you consider stops on a Florida to Florence, South Carolina flight.

Cheap Florida to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florida to Florence, South Carolina

Fastest flight time

3h 56m

Direct flights

None
The fastest flight from Florida to Florence, South Carolina takes 3h 56m
There are no direct flights from Florida to Florence, South Carolina. There are no popular flight routes from Florida to Florence, South Carolina.
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Frequently asked questions about flying from Florida to Florence, South Carolina

  • When did momondo last update prices for flights from Florida to Florence Airport?

    Prices for flights from Florida to Florence Airport were last updated today.

  • How old do you have to be to fly from Florida to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Florida to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Florida to Florence?

Finding the right flight to Florence from Florida is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florence quick and easy, saving you time and money.

Can I find flights from Florida to Florence with flexible booking policies on momondo?

All flight searches from Florida to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Florida to Florence?

momondo helps you find the best flight between Florida and Florence by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Florida to Florence right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Florence, momondo offers a useful price alert feature which will track prices for flights to Florence from Florida and alert you when they change.

An easier way to manage your Florence, South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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