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Cheap flights from Florida to Florence from $279

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Florida to Florence departing on 5/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Florida to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:13 am - 11:08 pm
PBI
-
FLO
12h 55m
2 stops
American Airlines Logo
5:16 am - 5:32 pm
FLO
-
PBI
12h 16m
2 stops
$355American Airlines
Wed, Feb 18 - Sun, Feb 22
American Airlines Logo
7:35 pm - 11:57 pm
TPA
-
FLO
4h 22m
1 stop
American Airlines Logo
6:20 pm - 12:29 am
FLO
-
TPA
6h 09m
1 stop
$407American Airlines
Wed, Mar 11 - Wed, Mar 18
American Airlines Logo
2:18 pm - 11:57 pm
TPA
-
FLO
9h 39m
2 stops
American Airlines Logo
5:16 am - 11:00 am
FLO
-
TPA
5h 44m
1 stop
$412American Airlines
Wed, Mar 11 - Wed, Mar 18
American Airlines Logo
6:40 am - 5:21 pm
MCO
-
FLO
10h 41m
2 stops
American Airlines Logo
5:16 am - 5:05 pm
FLO
-
MCO
11h 49m
2 stops
$414American Airlines
Wed, Feb 18 - Sun, Feb 22
American Airlines Logo
7:00 am - 5:50 pm
TPA
-
FLO
10h 50m
2 stops
American Airlines Logo
5:16 am - 3:04 pm
FLO
-
TPA
9h 48m
2 stops
$417American Airlines
Wed, Mar 11 - Wed, Mar 18
American Airlines Logo
12:00 pm - 5:50 pm
MCO
-
FLO
5h 50m
1 stop
American Airlines Logo
5:16 am - 11:10 am
FLO
-
MCO
5h 54m
1 stop
$431American Airlines
Thu, Mar 19 - Sat, Mar 21
American Airlines Logo
8:44 am - 5:50 pm
MCO
-
FLO
9h 06m
2 stops
American Airlines Logo
5:16 am - 9:28 am
FLO
-
MCO
4h 12m
1 stop
$436American Airlines
Thu, Mar 19 - Sat, Mar 21
American Airlines Logo
4:50 pm - 11:08 pm
TPA
-
FLO
6h 18m
1 stop
American Airlines Logo
5:16 am - 11:00 am
FLO
-
TPA
5h 44m
1 stop
$437American Airlines
Wed, Mar 4 - Wed, Mar 11
American Airlines Logo
2:18 pm - 11:08 pm
TPA
-
FLO
8h 50m
2 stops
American Airlines Logo
5:16 am - 11:00 am
FLO
-
TPA
5h 44m
1 stop
$442American Airlines
Wed, Mar 4 - Wed, Mar 11
American Airlines Logo
9:10 am - 5:21 pm
TPA
-
FLO
8h 11m
2 stops
American Airlines Logo
5:16 am - 3:04 pm
FLO
-
TPA
9h 48m
2 stops
$447American Airlines
Wed, Mar 4 - Wed, Mar 11

American Airlines flights from Florida to Florence, South Carolina

Our best American Airlines deals on Florida to Florence, South Carolina flight tickets
American Airlines
Feb 18
PBI10:13 amPalm Beach Intl
12h 55m
2 stops
FLO11:08 pmFlorence
Feb 22
FLO5:16 amFlorence
12h 16m
2 stops
PBI5:32 pmPalm Beach Intl
$355
American Airlines
Mar 11
TPA7:35 pmTampa
4h 22m
1 stop
FLO11:57 pmFlorence
Mar 18
FLO6:20 pmFlorence
6h 09m
1 stop
TPA12:29 amTampa
$407
American Airlines
Mar 11
TPA2:18 pmTampa
9h 39m
2 stops
FLO11:57 pmFlorence
Mar 18
FLO5:16 amFlorence
5h 44m
1 stop
TPA11:00 amTampa
$412

momondo Fare Finder

 
Customize your flight search to find flights from Florida to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Florida to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

West Palm BeachFlorence

PBI - FLO

PBIFLO

Palm Beach Intl

Wed 2/18

10:13 am-11:08 pm

2 stops12h 55m

Florence

Sun 2/22

5:16 am-5:32 pm

2 stops12h 16m

$355

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Wed 3/11

7:35 pm-11:57 pm

1 stop4h 22m

Florence

Wed 3/18

6:20 pm-12:29 am

1 stop6h 09m

$407

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Wed 3/11

2:18 pm-11:57 pm

2 stops9h 39m

Florence

Wed 3/18

5:16 am-11:00 am

1 stop5h 44m

$412

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Wed 2/18

6:40 am-5:21 pm

2 stops10h 41m

Florence

Sun 2/22

5:16 am-5:05 pm

2 stops11h 49m

$414

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Wed 3/11

7:00 am-5:50 pm

2 stops10h 50m

Florence

Wed 3/18

5:16 am-3:04 pm

2 stops9h 48m

$417

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Thu 3/19

12:00 pm-5:50 pm

1 stop5h 50m

Florence

Sat 3/21

5:16 am-11:10 am

1 stop5h 54m

$431

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Thu 3/19

8:44 am-5:50 pm

2 stops9h 06m

Florence

Sat 3/21

5:16 am-9:28 am

1 stop4h 12m

$436

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Wed 3/4

4:50 pm-11:08 pm

1 stop6h 18m

Florence

Wed 3/11

5:16 am-11:00 am

1 stop5h 44m

$437

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Wed 3/4

2:18 pm-11:08 pm

2 stops8h 50m

Florence

Wed 3/11

5:16 am-11:00 am

1 stop5h 44m

$442

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Wed 3/4

9:10 am-5:21 pm

2 stops8h 11m

Florence

Wed 3/11

5:16 am-3:04 pm

2 stops9h 48m

$447

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Florida to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Florida to Florence, South Carolina flights?

You could potentially save up to 54% on your flight if you consider stops on a Florida to Florence, South Carolina flight.

Cheap Florida to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florida to Florence, South Carolina

Fastest flight time

3h 59m

Direct flights

None
The fastest flight from Florida to Florence, South Carolina takes 3h 59m
There are no direct flights from Florida to Florence, South Carolina. There are no popular flight routes from Florida to Florence, South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Florida to Florence Airport?

    Prices for flights from Florida to Florence Airport were last updated today.

  • How many operators does momondo search for flights from Florida to Florence Airport?

  • How old do you have to be to fly from Florida to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Florida to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Florida to Florence, South Carolina

Compare and see reviews for airlines that fly from Florida to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $410Free CancellationRating
7.2
11,237 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Florida to Florence?

Finding the right flight to Florence from Florida is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florence quick and easy, saving you time and money.

Can I find flights from Florida to Florence with flexible booking policies on momondo?

All flight searches from Florida to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Florida to Florence?

momondo helps you find the best flight between Florida and Florence by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Florida to Florence right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Florence, momondo offers a useful price alert feature which will track prices for flights to Florence from Florida and alert you when they change.

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