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Cheap flights from Detroit Metropolitan Wayne County Airport to Panama City from $160

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Panama City departing on 7/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:43 pm - 10:40 pm
DTW
-
ECP
4h 57m
1 stop
American Airlines Logo
5:48 pm - 11:32 pm
ECP
-
DTW
4h 44m
1 stop
$301American Airlines
Thu, Aug 20 - Mon, Aug 24
United Airlines Logo
8:50 am - 1:24 pm
DTW
-
ECP
5h 34m
1 stop
United Airlines Logo
10:25 am - 6:38 pm
ECP
-
DTW
7h 13m
1 stop
$303United Airlines
Tue, Jul 7 - Sat, Jul 11
American Airlines Logo
7:30 am - 11:12 am
DTW
-
ECP
4h 42m
1 stop
American Airlines Logo
6:40 am - 2:10 pm
ECP
-
DTW
6h 30m
1 stop
$316American Airlines
Fri, Aug 21 - Tue, Aug 25
American Airlines Logo
1:41 pm - 6:22 pm
DTW
-
ECP
5h 41m
1 stop
American Airlines Logo
4:17 pm - 12:41 am
ECP
-
DTW
7h 24m
1 stop
$318American Airlines
Fri, Jul 17 - Tue, Jul 21
Delta Logo
7:40 pm - 11:37 pm
DTW
-
ECP
4h 57m
1 stop
Delta Logo
5:03 pm - 12:59 am
ECP
-
DTW
6h 56m
1 stop
$319Delta
Wed, Jul 15 - Wed, Jul 22
Delta Logo
9:25 am - 12:42 pm
DTW
-
ECP
4h 17m
1 stop
Delta Logo
4:28 pm - 10:19 pm
ECP
-
DTW
4h 51m
1 stop
$321Delta
Sat, Sep 5 - Mon, Sep 14
United Airlines Logo
6:00 am - 1:24 pm
DTW
-
ECP
8h 24m
2 stops
United Airlines Logo
10:25 am - 6:38 pm
ECP
-
DTW
7h 13m
1 stop
$324United Airlines
Sat, Jul 4 - Wed, Jul 8
Delta Logo
7:35 pm - 11:37 pm
DTW
-
ECP
5h 02m
1 stop
Delta Logo
5:03 pm - 12:59 am
ECP
-
DTW
6h 56m
1 stop
$329Delta
Thu, Jul 9 - Mon, Jul 20
Southwest Logo
1:25 pm - 7:45 pm
DTW
-
ECP
7h 20m
2 stops
Southwest Logo
6:20 pm - 12:10 am
ECP
-
DTW
4h 50m
1 stop
$330Southwest
Tue, Jul 14 - Thu, Jul 16
American Airlines Logo
6:00 am - 10:28 am
DTW
-
ECP
5h 28m
1 stop
American Airlines Logo
6:54 pm - 12:41 am
ECP
-
DTW
4h 47m
1 stop
$331American Airlines
Wed, Jul 1 - Tue, Jul 7

American Airlines flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to Panama City, Florida flight tickets
American Airlines
Aug 20
DTW6:43 pmDetroit Metropolitan Wayne County
4h 57m
1 stop
ECP10:40 pmPanama City NW Florida Beaches
Aug 24
ECP5:48 pmPanama City NW Florida Beaches
4h 44m
1 stop
DTW11:32 pmDetroit Metropolitan Wayne County
$301
American Airlines
Jul 15
DTW6:00 amDetroit Metropolitan Wayne County
5h 27m
1 stop
ECP10:27 amPanama City NW Florida Beaches
Jul 22
ECP7:05 amPanama City NW Florida Beaches
7h 26m
1 stop
DTW3:31 pmDetroit Metropolitan Wayne County
$303
American Airlines
Jul 17
DTW1:41 pmDetroit Metropolitan Wayne County
5h 41m
1 stop
ECP6:22 pmPanama City NW Florida Beaches
Jul 21
ECP4:17 pmPanama City NW Florida Beaches
7h 24m
1 stop
DTW12:41 amDetroit Metropolitan Wayne County
$318

Delta flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Our best Delta deals on Detroit Metropolitan Wayne County Airport to Panama City, Florida flight tickets
Delta
Jul 4
DTW5:59 pmDetroit Metropolitan Wayne County
5h 00m
1 stop
ECP9:59 pmPanama City NW Florida Beaches
Jul 8
ECP5:03 pmPanama City NW Florida Beaches
4h 30m
1 stop
DTW10:33 pmDetroit Metropolitan Wayne County
$319
Delta
Jul 9
DTW7:35 pmDetroit Metropolitan Wayne County
5h 02m
1 stop
ECP11:37 pmPanama City NW Florida Beaches
Jul 20
ECP5:03 pmPanama City NW Florida Beaches
6h 56m
1 stop
DTW12:59 amDetroit Metropolitan Wayne County
$329
Delta
Jul 4
DTW5:59 pmDetroit Metropolitan Wayne County
5h 00m
1 stop
ECP9:59 pmPanama City NW Florida Beaches
Jul 7
ECP5:03 pmPanama City NW Florida Beaches
6h 56m
1 stop
DTW12:59 amDetroit Metropolitan Wayne County
$339

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 6, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Thu 8/20

6:43 pm-10:40 pm

1 stop4h 57m

Panama City NW Florida Beaches

Mon 8/24

5:48 pm-11:32 pm

1 stop4h 44m

$301

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 7/7

8:50 am-1:24 pm

1 stop5h 34m

Panama City NW Florida Beaches

Sat 7/11

10:25 am-6:38 pm

1 stop7h 13m

$303

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 8/21

7:30 am-11:12 am

1 stop4h 42m

Panama City NW Florida Beaches

Tue 8/25

6:40 am-2:10 pm

1 stop6h 30m

$316

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 7/17

1:41 pm-6:22 pm

1 stop5h 41m

Panama City NW Florida Beaches

Tue 7/21

4:17 pm-12:41 am

1 stop7h 24m

$318

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 7/15

7:40 pm-11:37 pm

1 stop4h 57m

Panama City NW Florida Beaches

Wed 7/22

5:03 pm-12:59 am

1 stop6h 56m

$319
Quickest round-trip

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 9/5

9:25 am-12:42 pm

1 stop4h 17m

Panama City NW Florida Beaches

Mon 9/14

4:28 pm-10:19 pm

1 stop4h 51m

$321

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 7/4

6:00 am-1:24 pm

2 stops8h 24m

Panama City NW Florida Beaches

Wed 7/8

10:25 am-6:38 pm

1 stop7h 13m

$324

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Thu 7/9

7:35 pm-11:37 pm

1 stop5h 02m

Panama City NW Florida Beaches

Mon 7/20

5:03 pm-12:59 am

1 stop6h 56m

$329

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 7/14

1:25 pm-7:45 pm

2 stops7h 20m

Panama City NW Florida Beaches

Thu 7/16

6:20 pm-12:10 am

1 stop4h 50m

$330

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 7/1

6:00 am-10:28 am

1 stop5h 28m

Panama City NW Florida Beaches

Tue 7/7

6:54 pm-12:41 am

1 stop4h 47m

$331

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit Metropolitan Wayne County Airport and Panama City, Florida?

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Detroit Metropolitan Wayne County Airport is in September. Flight prices, which tend to average around $266, are often lower during this time because this is during the off-season. The month of January is another great option to travel to Panama City, Florida, with average flight prices from Detroit Metropolitan Wayne County Airport averaging around $285.

How far in advance should I book a flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $346 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Detroit Metropolitan Wayne County Airport for as low as $247 on momondo.

How have Detroit Metropolitan Wayne County Airport to Panama City, Florida flight prices changed over time?

As of June 2026, prices for Detroit Metropolitan Wayne County Airport to Panama City, Florida flights are approximately 13% cheaper when compared to flights at the same time last year.

When to book flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Panama City, Florida (DTW to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Fastest flight time

3h 57m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida takes 3h 57m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Panama City, Florida.
Search flight deals

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to Panama City, Florida

  • How far is Detroit Metropolitan Wayne County to Panama City NW Florida Beaches by plane?

    There are 842.6 mi between Detroit Metropolitan Wayne County and Panama City NW Florida Beaches. By plane, this route typically takes 3h 57m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport are updated daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents required for your trip to Panama City NW Florida Beaches Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City NW Florida Beaches Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Detroit Metropolitan Wayne County Airport to Panama City, Florida?

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Panama City, Florida?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $208Free CancellationRating
7.8
8,395 reviews
Search Delta flights
SouthwestPriceFrom $228Free CancellationRating
8.0
4,258 reviews
Search Southwest flights
American AirlinesPriceFrom $237Free CancellationRating
7.1
11,651 reviews
Search American Airlines flights
United AirlinesPriceFrom $238Free CancellationRating
7.4
9,777 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

Finding the right flight to Panama City from Detroit is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

Flights from Detroit to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Detroit to Panama City.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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