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Cheap flights from Detroit Metropolitan Wayne County Airport to Panama City from $120

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Panama City departing on 4/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
10:00 am - 11:15 am
DTW
-
ECP
2h 15mnonstop
Delta Logo
12:05 pm - 3:37 pm
ECP
-
DTW
2h 32mnonstop
$219Delta
Sat, Jun 27 - Sun, Jul 5
Delta Logo
10:00 am - 11:15 am
DTW
-
ECP
2h 15mnonstop
Delta Logo
6:00 am - 12:33 pm
ECP
-
DTW
5h 33m
1 stop
$229Delta
Sat, Aug 22 - Tue, Aug 25
Southwest Logo
3:40 pm - 7:00 pm
DTW
-
ECP
4h 20m
1 stop
Southwest Logo
7:55 am - 1:05 pm
ECP
-
DTW
4h 10m
1 stop
$233Southwest
Sat, Apr 18 - Sat, Apr 25
United Airlines Logo
6:00 am - 9:48 am
DTW
-
ECP
4h 48m
1 stop
United Airlines Logo
4:57 pm - 11:57 pm
ECP
-
DTW
6h 00m
1 stop
$234United Airlines
Tue, Apr 21 - Tue, Apr 21
Delta Logo
6:17 pm - 11:12 pm
DTW
-
ECP
5h 55m
1 stop
Delta Logo
5:10 pm - 11:39 pm
ECP
-
DTW
5h 29m
1 stop
$239Delta
Sat, Apr 25 - Wed, Apr 29
Southwest Logo
3:40 pm - 7:00 pm
DTW
-
ECP
4h 20m
1 stop
Southwest Logo
9:55 am - 9:25 pm
ECP
-
DTW
10h 30m
2 stops
$244Southwest
Sat, Apr 18 - Sat, Apr 25
Southwest Logo
8:35 am - 5:50 pm
DTW
-
ECP
10h 15m
2 stops
Southwest Logo
9:55 am - 9:25 pm
ECP
-
DTW
10h 30m
2 stops
$249Southwest
Sat, Apr 25 - Sat, May 2
United Airlines Logo
6:15 am - 12:04 pm
DTW
-
ECP
6h 49m
1 stop
United Airlines Logo
10:19 am - 5:31 pm
ECP
-
DTW
6h 12m
1 stop
$259United Airlines
Tue, Mar 24 - Tue, Mar 31
United Airlines Logo
7:31 am - 4:11 pm
DTW
-
ECP
9h 40m
2 stops
United Airlines Logo
10:19 am - 6:18 pm
ECP
-
DTW
6h 59m
1 stop
$264United Airlines
Tue, Mar 24 - Tue, Mar 31
United Airlines Logo
11:00 am - 9:59 pm
DTW
-
ECP
11h 59m
2 stops
United Airlines Logo
2:19 pm - 10:17 pm
ECP
-
DTW
6h 58m
1 stop
$265United Airlines
Mon, Apr 13 - Mon, Apr 20

Southwest flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Our best Southwest deals on Detroit Metropolitan Wayne County Airport to Panama City, Florida flight tickets
Southwest
Apr 18
DTW3:40 pmDetroit Metropolitan Wayne County
4h 20m
1 stop
ECP7:00 pmPanama City NW Florida Beaches
Apr 25
ECP7:55 amPanama City NW Florida Beaches
4h 10m
1 stop
DTW1:05 pmDetroit Metropolitan Wayne County
$233
Southwest
Apr 18
DTW3:40 pmDetroit Metropolitan Wayne County
4h 20m
1 stop
ECP7:00 pmPanama City NW Florida Beaches
Apr 25
ECP9:55 amPanama City NW Florida Beaches
10h 30m
2 stops
DTW9:25 pmDetroit Metropolitan Wayne County
$244
Southwest
Apr 25
DTW8:35 amDetroit Metropolitan Wayne County
10h 15m
2 stops
ECP5:50 pmPanama City NW Florida Beaches
May 2
ECP9:55 amPanama City NW Florida Beaches
10h 30m
2 stops
DTW9:25 pmDetroit Metropolitan Wayne County
$249

United Airlines flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Our best United Airlines deals on Detroit Metropolitan Wayne County Airport to Panama City, Florida flight tickets
United Airlines
Apr 21
DTW6:00 amDetroit Metropolitan Wayne County
4h 48m
1 stop
ECP9:48 amPanama City NW Florida Beaches
Apr 21
ECP4:57 pmPanama City NW Florida Beaches
6h 00m
1 stop
DTW11:57 pmDetroit Metropolitan Wayne County
$234
United Airlines
Mar 24
DTW6:15 amDetroit Metropolitan Wayne County
6h 49m
1 stop
ECP12:04 pmPanama City NW Florida Beaches
Mar 31
ECP10:19 amPanama City NW Florida Beaches
6h 12m
1 stop
DTW5:31 pmDetroit Metropolitan Wayne County
$259
United Airlines
Mar 24
DTW7:31 amDetroit Metropolitan Wayne County
9h 40m
2 stops
ECP4:11 pmPanama City NW Florida Beaches
Mar 31
ECP10:19 amPanama City NW Florida Beaches
6h 59m
1 stop
DTW6:18 pmDetroit Metropolitan Wayne County
$264

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 2, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 6/27

10:00 am-11:15 am

Nonstop2h 15m

Panama City NW Florida Beaches

Sun 7/5

12:05 pm-3:37 pm

Nonstop2h 32m

$219

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 8/22

10:00 am-11:15 am

Nonstop2h 15m

Panama City NW Florida Beaches

Tue 8/25

6:00 am-12:33 pm

1 stop5h 33m

$229

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 4/18

3:40 pm-7:00 pm

1 stop4h 20m

Panama City NW Florida Beaches

Sat 4/25

7:55 am-1:05 pm

1 stop4h 10m

$233

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 4/21

6:00 am-9:48 am

1 stop4h 48m

Panama City NW Florida Beaches

Tue 4/21

4:57 pm-11:57 pm

1 stop6h 00m

$234

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 4/25

6:17 pm-11:12 pm

1 stop5h 55m

Panama City NW Florida Beaches

Wed 4/29

5:10 pm-11:39 pm

1 stop5h 29m

$239

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 4/18

3:40 pm-7:00 pm

1 stop4h 20m

Panama City NW Florida Beaches

Sat 4/25

9:55 am-9:25 pm

2 stops10h 30m

$244

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 4/25

8:35 am-5:50 pm

2 stops10h 15m

Panama City NW Florida Beaches

Sat 5/2

9:55 am-9:25 pm

2 stops10h 30m

$249

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 3/24

6:15 am-12:04 pm

1 stop6h 49m

Panama City NW Florida Beaches

Tue 3/31

10:19 am-5:31 pm

1 stop6h 12m

$259

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 3/24

7:31 am-4:11 pm

2 stops9h 40m

Panama City NW Florida Beaches

Tue 3/31

10:19 am-6:18 pm

1 stop6h 59m

$264

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Mon 4/13

11:00 am-9:59 pm

2 stops11h 59m

Panama City NW Florida Beaches

Mon 4/20

2:19 pm-10:17 pm

1 stop6h 58m

$265

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Detroit Metropolitan Wayne County Airport is in September. Flight prices, which tend to average around $258, are often lower during this time because this is during the off-season. The month of July is another great option to travel to Panama City, Florida, with average flight prices from Detroit Metropolitan Wayne County Airport averaging around $268.

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $341 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Detroit Metropolitan Wayne County Airport for as low as $241 on momondo.

How have Detroit Metropolitan Wayne County Airport to Panama City, Florida flight prices changed over time?

As of March 2026, prices for Detroit Metropolitan Wayne County Airport to Panama City, Florida flights are approximately 34% more expensive when compared to flights at the same time last year.

When to book flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Panama City, Florida (DTW to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Fastest flight time

2h 15m

Direct flights

Sun

Airports in Panama City, Florida

1 airport
The fastest flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida takes 2h 15m
Direct flights go from Detroit Metropolitan Wayne County Airport to Panama City, Florida on Sunday. There are no airlines offering direct flights.
There is 1 airport in Panama City, Florida. From Detroit Metropolitan Wayne County Airport there are direct flights to Panama City NW Florida Beaches (ECP).
Search flight deals

  • How far is Detroit Metropolitan Wayne County to Panama City NW Florida Beaches by plane?

    There are 842.6 mi between Detroit Metropolitan Wayne County and Panama City NW Florida Beaches. By plane, this route typically takes 2h 15m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport are updated daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents required for your trip to Panama City NW Florida Beaches Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City NW Florida Beaches Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Detroit Metropolitan Wayne County Airport to Panama City, Florida?

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Panama City, Florida?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
8,237 reviews
Search Delta flights
American AirlinesPriceFrom $228Free CancellationRating
7.1
11,369 reviews
Search American Airlines flights
SouthwestPriceFrom $228Free CancellationRating
8.0
4,306 reviews
Search Southwest flights
United AirlinesPriceFrom $238Free CancellationRating
7.4
9,375 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

Finding the right flight to Panama City from Detroit is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

Flights from Detroit to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Detroit to Panama City.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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