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Cheap flights from Detroit Metropolitan Wayne County Airport to Panama City from $106

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Panama City departing on 5/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:34 pm - 10:51 pm
DTW
-
ECP
5h 17m
1 stop
Delta Logo
6:00 am - 10:54 am
ECP
-
DTW
3h 54m
1 stop
$319Delta
Sat, Jun 6 - Sat, Jun 13
Delta Logo
4:30 pm - 11:28 pm
DTW
-
ECP
7h 58m
1 stop
Delta Logo
6:00 am - 11:14 am
ECP
-
DTW
4h 14m
1 stop
$323Delta
Thu, Jun 4 - Tue, Jun 9
Southwest Logo
1:25 pm - 9:10 pm
DTW
-
ECP
8h 45m
2 stops
Southwest Logo
5:25 pm - 10:25 pm
ECP
-
DTW
4h 00m
1 stop
$324Southwest
Tue, Jun 9 - Tue, Jun 16
Southwest Logo
4:10 pm - 6:55 pm
DTW
-
ECP
3h 45m
1 stop
Southwest Logo
12:05 pm - 6:20 pm
ECP
-
DTW
5h 15m
1 stop
$327Southwest
Wed, May 6 - Wed, May 13
Southwest Logo
1:40 pm - 8:25 pm
DTW
-
ECP
7h 45m
2 stops
Southwest Logo
2:25 pm - 10:50 pm
ECP
-
DTW
7h 25m
2 stops
$329Southwest
Tue, Jun 2 - Tue, Jun 9
Southwest Logo
4:10 pm - 6:55 pm
DTW
-
ECP
3h 45m
1 stop
Southwest Logo
12:05 pm - 10:30 pm
ECP
-
DTW
9h 25m
2 stops
$332Southwest
Wed, May 6 - Wed, May 13
Southwest Logo
1:25 pm - 9:10 pm
DTW
-
ECP
8h 45m
2 stops
Southwest Logo
7:00 am - 7:30 pm
ECP
-
DTW
11h 30m
2 stops
$335Southwest
Tue, Jun 9 - Tue, Jun 16
American Airlines Logo
6:00 am - 10:28 am
DTW
-
ECP
5h 28m
1 stop
American Airlines Logo
6:45 pm - 12:33 am
ECP
-
DTW
4h 48m
1 stop
$339American Airlines
Tue, May 26 - Sun, May 31
American Airlines Logo
5:29 pm - 11:40 pm
DTW
-
ECP
7h 11m
2 stops
American Airlines Logo
3:48 pm - 11:53 pm
ECP
-
DTW
7h 05m
1 stop
$344American Airlines
Tue, May 26 - Sun, May 31
United Airlines Logo
11:00 am - 8:03 pm
DTW
-
ECP
10h 03m
2 stops
United Airlines Logo
2:05 pm - 10:19 pm
ECP
-
DTW
7h 14m
1 stop
$349United Airlines
Fri, Aug 7 - Mon, Aug 10

Southwest flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Our best Southwest deals on Detroit Metropolitan Wayne County Airport to Panama City, Florida flight tickets
Southwest
Jun 9
DTW1:25 pmDetroit Metropolitan Wayne County
8h 45m
2 stops
ECP9:10 pmPanama City NW Florida Beaches
Jun 16
ECP5:25 pmPanama City NW Florida Beaches
4h 00m
1 stop
DTW10:25 pmDetroit Metropolitan Wayne County
$324
Southwest
May 6
DTW4:10 pmDetroit Metropolitan Wayne County
3h 45m
1 stop
ECP6:55 pmPanama City NW Florida Beaches
May 13
ECP12:05 pmPanama City NW Florida Beaches
5h 15m
1 stop
DTW6:20 pmDetroit Metropolitan Wayne County
$327
Southwest
Jun 2
DTW1:40 pmDetroit Metropolitan Wayne County
7h 45m
2 stops
ECP8:25 pmPanama City NW Florida Beaches
Jun 9
ECP2:25 pmPanama City NW Florida Beaches
7h 25m
2 stops
DTW10:50 pmDetroit Metropolitan Wayne County
$329

American Airlines flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to Panama City, Florida flight tickets
American Airlines
May 26
DTW6:00 amDetroit Metropolitan Wayne County
5h 28m
1 stop
ECP10:28 amPanama City NW Florida Beaches
May 31
ECP6:45 pmPanama City NW Florida Beaches
4h 48m
1 stop
DTW12:33 amDetroit Metropolitan Wayne County
$339
American Airlines
May 26
DTW5:29 pmDetroit Metropolitan Wayne County
7h 11m
2 stops
ECP11:40 pmPanama City NW Florida Beaches
May 31
ECP3:48 pmPanama City NW Florida Beaches
7h 05m
1 stop
DTW11:53 pmDetroit Metropolitan Wayne County
$344
American Airlines
Jun 6
DTW4:53 pmDetroit Metropolitan Wayne County
7h 47m
2 stops
ECP11:40 pmPanama City NW Florida Beaches
Jun 13
ECP3:48 pmPanama City NW Florida Beaches
5h 37m
1 stop
DTW10:25 pmDetroit Metropolitan Wayne County
$354

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 20, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 6/6

6:34 pm-10:51 pm

1 stop5h 17m

Panama City NW Florida Beaches

Sat 6/13

6:00 am-10:54 am

1 stop3h 54m

$319

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Thu 6/4

4:30 pm-11:28 pm

1 stop7h 58m

Panama City NW Florida Beaches

Tue 6/9

6:00 am-11:14 am

1 stop4h 14m

$323

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 6/9

1:25 pm-9:10 pm

2 stops8h 45m

Panama City NW Florida Beaches

Tue 6/16

5:25 pm-10:25 pm

1 stop4h 00m

$324
Quickest round-trip

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 5/6

4:10 pm-6:55 pm

1 stop3h 45m

Panama City NW Florida Beaches

Wed 5/13

12:05 pm-6:20 pm

1 stop5h 15m

$327

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 6/2

1:40 pm-8:25 pm

2 stops7h 45m

Panama City NW Florida Beaches

Tue 6/9

2:25 pm-10:50 pm

2 stops7h 25m

$329

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 5/6

4:10 pm-6:55 pm

1 stop3h 45m

Panama City NW Florida Beaches

Wed 5/13

12:05 pm-10:30 pm

2 stops9h 25m

$332

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 6/9

1:25 pm-9:10 pm

2 stops8h 45m

Panama City NW Florida Beaches

Tue 6/16

7:00 am-7:30 pm

2 stops11h 30m

$335

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 5/26

6:00 am-10:28 am

1 stop5h 28m

Panama City NW Florida Beaches

Sun 5/31

6:45 pm-12:33 am

1 stop4h 48m

$339

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 5/26

5:29 pm-11:40 pm

2 stops7h 11m

Panama City NW Florida Beaches

Sun 5/31

3:48 pm-11:53 pm

1 stop7h 05m

$344

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 8/7

11:00 am-8:03 pm

2 stops10h 03m

Panama City NW Florida Beaches

Mon 8/10

2:05 pm-10:19 pm

1 stop7h 14m

$349

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit Metropolitan Wayne County Airport and Panama City, Florida?

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Detroit Metropolitan Wayne County Airport is in September. Flight prices, which tend to average around $258, are often lower during this time because this is during the off-season. The month of July is another great option to travel to Panama City, Florida, with average flight prices from Detroit Metropolitan Wayne County Airport averaging around $277.

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $342 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Detroit Metropolitan Wayne County Airport for as low as $247 on momondo.

How have Detroit Metropolitan Wayne County Airport to Panama City, Florida flight prices changed over time?

As of April 2026, prices for Detroit Metropolitan Wayne County Airport to Panama City, Florida flights are approximately 21% more expensive when compared to flights at the same time last year.

When to book flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Panama City, Florida (DTW to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Fastest flight time

2h 15m

Direct flights

Mon and Sun

Airports in Panama City, Florida

1 airport
The fastest flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida takes 2h 15m
Direct flights go from Detroit Metropolitan Wayne County Airport to Panama City, Florida on Monday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Panama City, Florida. From Detroit Metropolitan Wayne County Airport there are direct flights to Panama City NW Florida Beaches (ECP).
Search flight deals

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to Panama City, Florida

  • How far is Detroit Metropolitan Wayne County to Panama City NW Florida Beaches by plane?

    There are 842.6 mi between Detroit Metropolitan Wayne County and Panama City NW Florida Beaches. By plane, this route typically takes 2h 15m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport are updated daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents required for your trip to Panama City NW Florida Beaches Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City NW Florida Beaches Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Detroit Metropolitan Wayne County Airport to Panama City, Florida?

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Panama City, Florida?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
8,422 reviews
Search Delta flights
American AirlinesPriceFrom $237Free CancellationRating
7.1
11,625 reviews
Search American Airlines flights
United AirlinesPriceFrom $238Free CancellationRating
7.4
9,607 reviews
Search United Airlines flights
SouthwestPriceFrom $238Free CancellationRating
8.0
4,330 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

Finding the right flight to Panama City from Detroit is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

Flights from Detroit to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Detroit to Panama City.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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