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Cheap flights from Detroit Metropolitan Wayne County Airport to Panama City from $120

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Panama City departing on 2/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:11 am - 12:41 pmDTW-ECP
8h 30m1 stop
American Airlines Logo
5:50 pm - 11:39 pmECP-DTW
4h 49m1 stop
$239American Airlines
Find Deal
Sat, Nov 8 - Tue, Nov 11
American Airlines Logo
5:08 pm - 11:15 pmDTW-ECP
7h 07m1 stop
American Airlines Logo
8:21 am - 7:14 pmECP-DTW
9h 53m2 stops
$244American Airlines
Find Deal
Fri, Nov 14 - Wed, Nov 19
American Airlines Logo
2:16 pm - 11:15 pmDTW-ECP
9h 59m2 stops
American Airlines Logo
12:00 pm - 10:16 pmECP-DTW
9h 16m2 stops
$249American Airlines
Find Deal
Fri, Nov 14 - Wed, Nov 19
Delta Logo
9:25 am - 12:40 pmDTW-ECP
4h 15m1 stop
Delta Logo
7:45 am - 12:36 pmECP-DTW
3h 51m1 stop
$259Delta
Find Deal
Wed, Jan 7 - Tue, Jan 13
United Airlines Logo
5:45 am - 4:03 pmDTW-ECP
11h 18m2 stops
United Airlines Logo
5:00 pm - 11:42 pmECP-DTW
5h 42m1 stop
$264United Airlines
Find Deal
Tue, Nov 4 - Fri, Nov 7
American Airlines Logo
11:09 am - 5:18 pmDTW-ECP
7h 09m2 stops
American Airlines Logo
12:08 pm - 11:21 pmECP-DTW
10h 13m2 stops
$269American Airlines
Find Deal
Fri, Dec 5 - Mon, Dec 8
Southwest Logo
5:25 pm - 9:05 pmDTW-ECP
4h 40m1 stop
Southwest Logo
5:35 pm - 10:20 pmECP-DTW
3h 45m1 stop
$296Southwest
Find Deal
Fri, Nov 7 - Mon, Nov 10
Delta Logo
8:55 am - 2:30 pmDTW-ECP
6h 35m1 stop
Delta Logo
6:00 am - 11:10 amECP-DTW
4h 10m1 stop
$299Delta
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Thu, Oct 30 - Tue, Nov 4
United Airlines Logo
8:15 am - 4:12 pmDTW-ECP
8h 57m1 stop
United Airlines Logo
6:30 am - 3:57 pmECP-DTW
8h 27m1 stop
$309United Airlines
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Wed, Jan 7 - Fri, Jan 16
Southwest Logo
8:10 am - 4:20 pmDTW-ECP
9h 10m2 stops
Southwest Logo
7:20 am - 12:15 pmECP-DTW
3h 55m1 stop
$354Southwest
Find Deal
Sat, Mar 7 - Fri, Mar 13

Southwest flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Our best Southwest deals on Detroit Metropolitan Wayne County Airport to Panama City, Florida flight tickets
Southwest
Nov 7
DTW5:25 pmDetroit Metropolitan Wayne County
4h 40m
1 stop
ECP9:05 pmPanama City NW Florida Beaches
Nov 10
ECP5:35 pmPanama City NW Florida Beaches
3h 45m
1 stop
DTW10:20 pmDetroit Metropolitan Wayne County
$296
Find similar
Southwest
Mar 7
DTW8:10 amDetroit Metropolitan Wayne County
9h 10m
2 stops
ECP4:20 pmPanama City NW Florida Beaches
Mar 13
ECP7:20 amPanama City NW Florida Beaches
3h 55m
1 stop
DTW12:15 pmDetroit Metropolitan Wayne County
$354
Find similar
Southwest
Oct 11
DTW5:35 amDetroit Metropolitan Wayne County
4h 55m
1 stop
ECP9:30 amPanama City NW Florida Beaches
Oct 14
ECP7:45 amPanama City NW Florida Beaches
3h 55m
1 stop
DTW12:40 pmDetroit Metropolitan Wayne County
$448
Find similar

Delta flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Our best Delta deals on Detroit Metropolitan Wayne County Airport to Panama City, Florida flight tickets
Delta
Jan 7
DTW9:25 amDetroit Metropolitan Wayne County
4h 15m
1 stop
ECP12:40 pmPanama City NW Florida Beaches
Jan 13
ECP7:45 amPanama City NW Florida Beaches
3h 51m
1 stop
DTW12:36 pmDetroit Metropolitan Wayne County
$259
Find similar
Delta
Oct 30
DTW8:55 amDetroit Metropolitan Wayne County
6h 35m
1 stop
ECP2:30 pmPanama City NW Florida Beaches
Nov 4
ECP6:00 amPanama City NW Florida Beaches
4h 10m
1 stop
DTW11:10 amDetroit Metropolitan Wayne County
$299
Find similar
Delta
Feb 5
DTW5:20 amDetroit Metropolitan Wayne County
4h 00m
1 stop
ECP8:20 amPanama City NW Florida Beaches
Feb 8
ECP6:00 amPanama City NW Florida Beaches
4h 01m
1 stop
DTW11:01 amDetroit Metropolitan Wayne County
$306
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 7, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 11/8

5:11 am-12:41 pm

1 stop8h 30m

Panama City NW Florida Beaches

Tue 11/11

5:50 pm-11:39 pm

1 stop4h 49m

$239

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 11/14

5:08 pm-11:15 pm

1 stop7h 07m

Panama City NW Florida Beaches

Wed 11/19

8:21 am-7:14 pm

2 stops9h 53m

$244

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 11/14

2:16 pm-11:15 pm

2 stops9h 59m

Panama City NW Florida Beaches

Wed 11/19

12:00 pm-10:16 pm

2 stops9h 16m

$249

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 1/7

9:25 am-12:40 pm

1 stop4h 15m

Panama City NW Florida Beaches

Tue 1/13

7:45 am-12:36 pm

1 stop3h 51m

$259

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Tue 11/4

5:45 am-4:03 pm

2 stops11h 18m

Panama City NW Florida Beaches

Fri 11/7

5:00 pm-11:42 pm

1 stop5h 42m

$264

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 12/5

11:09 am-5:18 pm

2 stops7h 09m

Panama City NW Florida Beaches

Mon 12/8

12:08 pm-11:21 pm

2 stops10h 13m

$269

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Fri 11/7

5:25 pm-9:05 pm

1 stop4h 40m

Panama City NW Florida Beaches

Mon 11/10

5:35 pm-10:20 pm

1 stop3h 45m

$296

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Thu 10/30

8:55 am-2:30 pm

1 stop6h 35m

Panama City NW Florida Beaches

Tue 11/4

6:00 am-11:10 am

1 stop4h 10m

$299

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Wed 1/7

8:15 am-4:12 pm

1 stop8h 57m

Panama City NW Florida Beaches

Fri 1/16

6:30 am-3:57 pm

1 stop8h 27m

$309

DetroitPanama City

DTW - ECP

DTWECP

Detroit Metropolitan Wayne County

Sat 3/7

8:10 am-4:20 pm

2 stops9h 10m

Panama City NW Florida Beaches

Fri 3/13

7:20 am-12:15 pm

1 stop3h 55m

$354

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Detroit Metropolitan Wayne County Airport is in September. Flight prices, which tend to average around $262, are often lower during this time because this is during the off-season. The month of July is another great option to travel to Panama City, Florida, with average flight prices from Detroit Metropolitan Wayne County Airport averaging around $268.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $309. On the other hand, Friday is the most expensive day to depart from Detroit Metropolitan Wayne County Airport because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $436.

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $356 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Detroit Metropolitan Wayne County Airport for as low as $295 on momondo.

How have Detroit Metropolitan Wayne County Airport to Panama City, Florida flight prices changed over time?

As of October 2025, prices for Detroit Metropolitan Wayne County Airport to Panama City, Florida flights are approximately 42% cheaper when compared to flights at the same time last year.

When to book flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Panama City, Florida (DTW to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Direct flights

None
There are no direct flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Panama City, Florida.
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  • How far is Detroit Metropolitan Wayne County to Panama City NW Florida Beaches by plane?

    There are 842.6 mi between Detroit Metropolitan Wayne County and Panama City NW Florida Beaches. By plane, this route typically takes 3h 56m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport are updated daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents required for your trip to Panama City NW Florida Beaches Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City NW Florida Beaches Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Panama City, Florida?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Panama City, Florida

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $206Free CancellationRating
7.9
7,969 reviews
Search Delta flights
SouthwestPriceFrom $238Free CancellationRating
8.0
4,233 reviews
Search Southwest flights
American AirlinesPriceFrom $258Free CancellationRating
7.2
11,041 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

Finding the right flight to Panama City from Detroit is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

Flights from Detroit to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Detroit to Panama City.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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