Cheap flights from Des Moines to Pennsylvania from $33

The month of August is, on average, the cheapest month to fly to Pennsylvania from Des Moines, with most prices found around $295. If you don’t want to visit Pennsylvania in August, then you should wait until May to fly from Des Moines, when ticket prices are also cheap, with an average price of $318.

The cheapest day to depart on your flight to Pennsylvania is on a Thursday when prices can be found for as low as $346. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $616. These prices are subject to change though, so be sure to set up a Price Alert for flights to Pennsylvania.

Our most recent data shows that the best time of day to fly to Pennsylvania is in the afternoon. Flights from Des Moines to Pennsylvania during this time can be as low as $124. In contrast, the most expensive time of day to depart to Pennsylvania is at noon when prices are around $744.

Fly from Des Moines to Philadelphia for the best Des Moines - Pennsylvania flight prices

You are more likely to see cheaper flights to Pennsylvania from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Pennsylvania for around $347 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Pennsylvania from Des Moines for as low as $200 on momondo.

There are 4 cabin classes available to choose from on Des Moines to Pennsylvania flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Allegiant Air, Delta, and Southwest are the most popular carriers operating from Des Moines to Pennsylvania

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Pennsylvania from Des Moines according to our data. American Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Pennsylvania. Keep in mind that there are 6 different airlines that fly to Pennsylvania on a routine basis, so you have a few additional options to choose from.

The number of flights available between Des Moines and Pennsylvania is 3 per day as of July 2026. The most frequent departure time is 1:00PM, with 53% of daily flights leaving in the afternoon.

25 flights are operational weekly from Des Moines to Pennsylvania as of July 2026. The most popular departure day for this route is Thu, with 32% of flights per week taking off on this day.