What is the cheapest airline that flies from Des Moines to Indiana?

United Airlines, Southwest, and Delta are the most popular carriers operating from Des Moines to Indiana

What airlines fly to Indiana?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Indiana from Des Moines according to our data. American Airlines is the first choice among our users, with 41% of people opting to fly with this airline when traveling to Indiana. Keep in mind that there are 3 different airlines that fly to Indiana on a routine basis, so you have a few additional options to choose from.

How many flights depart from Des Moines to Indiana on average per week?

97 flights are operational weekly from Des Moines to Indiana as of February 2026. The most popular departure day for this route is Tue, with 38% of flights per week taking off on this day.

When did momondo last update prices for flights from Des Moines Airport to Indiana?

Prices for flights from Des Moines Airport to Indiana refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Indiana?

There are 3 operators available for flights from Des Moines Airport to Indiana as of February 2026.

How old do you have to be to fly from Des Moines Airport to Indiana?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Indiana.

What documentation or ID do you need to fly to Indiana?

The necessary travel and health documents for your Indiana trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$61 Cheap Flights from Des Moines to Indiana in 2026

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Find the cheapest flights from Des Moines to Indiana

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:44 pm - 9:17 pm

DSM

ORD

1h 33mnonstop

10:18 pm - 11:40 pm

ORD

DSM

1h 22mnonstop

$131American Airlines

Sat, Mar 7 - Sat, Mar 14

7:44 pm - 9:19 pm

DSM

ORD

1h 35mnonstop

4:54 pm - 6:19 pm

ORD

DSM

1h 25mnonstop

$151American Airlines

Wed, Apr 1 - Sat, Apr 4

2:04 pm - 3:41 pm

DSM

ORD

1h 37mnonstop

11:50 am - 1:23 pm

ORD

DSM

1h 33mnonstop

$157United Airlines

Tue, Mar 10 - Tue, Mar 17

3:40 pm - 4:55 pm

DSM

MDW

1h 15mnonstop

8:50 pm - 10:10 pm

MDW

DSM

1h 20mnonstop

$157Southwest

Wed, Apr 1 - Tue, Apr 7

6:55 am - 1:25 pm

DSM

MDW

6h 30m

1 stop

9:30 am - 3:42 pm

MDW

DSM

6h 12m

1 stop

$167Delta

Wed, Apr 1 - Sat, Apr 4

6:55 am - 11:35 am

DSM

ORD

4h 40m

1 stop

12:15 pm - 3:42 pm

ORD

DSM

3h 27m

1 stop

$167Delta

Wed, Apr 1 - Sat, Apr 4

6:55 pm - 8:31 pm

DSM

ORD

1h 36mnonstop

8:10 pm - 9:41 pm

ORD

DSM

1h 31mnonstop

$170United Airlines

Sat, Feb 28 - Mon, Mar 2

6:40 am - 4:10 pm

DSM

MDW

9h 30m

2 stops

8:50 pm - 10:10 pm

MDW

DSM

1h 20mnonstop

$172Southwest

Wed, Apr 1 - Tue, Apr 7

8:21 pm - 7:38 pm

DSM

IND

22h 17m

1 stop

8:33 pm - 7:16 pm

IND

DSM

23h 43m

1 stop

$287Frontier

Wed, Mar 11 - Sun, Mar 15

7:45 pm - 11:42 pm

DSM

CVG

26h 57m

1 stop

1:07 pm - 7:04 pm

CVG

DSM

30h 57m

2 stops

$319Frontier

Sun, Feb 22 - Thu, Feb 26

United Airlines flights from Des Moines to Indiana

Our best United Airlines deals on Des Moines to Indiana flight tickets

United Airlines

Mar 10

DSM2:04 pmDes Moines

1h 37m

ORD3:41 pmChicago O'Hare Intl

Mar 17

ORD11:50 amChicago O'Hare Intl

1h 33m

DSM1:23 pmDes Moines

$157

United Airlines

Feb 28

DSM6:55 pmDes Moines

1h 36m

ORD8:31 pmChicago O'Hare Intl

Mar 2

ORD8:10 pmChicago O'Hare Intl

1h 31m

DSM9:41 pmDes Moines

$170

United Airlines

Apr 10

DSM3:21 pmDes Moines

1h 32m

ORD4:53 pmChicago O'Hare Intl

Apr 13

ORD9:22 pmChicago O'Hare Intl

1h 37m

DSM10:59 pmDes Moines

$181

American Airlines flights from Des Moines to Indiana

Our best American Airlines deals on Des Moines to Indiana flight tickets

American Airlines

Mar 7

DSM7:44 pmDes Moines

1h 33m

ORD9:17 pmChicago O'Hare Intl

Mar 14

ORD10:18 pmChicago O'Hare Intl

1h 22m

DSM11:40 pmDes Moines

$131

American Airlines

Apr 1

DSM7:44 pmDes Moines

1h 35m

ORD9:19 pmChicago O'Hare Intl

Apr 4

ORD4:54 pmChicago O'Hare Intl

1h 25m

DSM6:19 pmDes Moines

$151

American Airlines

Feb 28

DSM7:44 pmDes Moines

1h 33m

ORD9:17 pmChicago O'Hare Intl

Mar 2

ORD7:37 amChicago O'Hare Intl

1h 24m

DSM9:01 amDes Moines

$152

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Sat 3/7

7:44 pm-9:17 pm

Nonstop1h 33m

Chicago O'Hare Intl

Sat 3/14

10:18 pm-11:40 pm

Nonstop1h 22m

$131

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Wed 4/1

7:44 pm-9:19 pm

Nonstop1h 35m

Chicago O'Hare Intl

Sat 4/4

4:54 pm-6:19 pm

Nonstop1h 25m

$151

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Tue 3/10

2:04 pm-3:41 pm

Nonstop1h 37m

Chicago O'Hare Intl

Tue 3/17

11:50 am-1:23 pm

Nonstop1h 33m

$157

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Wed 4/1

3:40 pm-4:55 pm

Nonstop1h 15m

Chicago Midway

Tue 4/7

8:50 pm-10:10 pm

Nonstop1h 20m

$157

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Wed 4/1

6:55 am-1:25 pm

1 stop6h 30m

Chicago Midway

Sat 4/4

9:30 am-3:42 pm

1 stop6h 12m

$167

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Wed 4/1

6:55 am-11:35 am

1 stop4h 40m

Chicago O'Hare Intl

Sat 4/4

12:15 pm-3:42 pm

1 stop3h 27m

$167

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Sat 2/28

6:55 pm-8:31 pm

Nonstop1h 36m

Chicago O'Hare Intl

Mon 3/2

8:10 pm-9:41 pm

Nonstop1h 31m

$170

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Wed 4/1

6:40 am-4:10 pm

2 stops9h 30m

Chicago Midway

Tue 4/7

8:50 pm-10:10 pm

Nonstop1h 20m

$172

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 3/11

8:21 pm-7:38 pm

1 stop22h 17m

Indianapolis

Sun 3/15

8:33 pm-7:16 pm

1 stop23h 43m

$287

Des MoinesCincinnati

DSM - CVG

DSMCVG

Des Moines

Sun 2/22

7:45 pm-11:42 pm

1 stop26h 57m

Cincinnati Cinci./N. Kentucky

Thu 2/26

1:07 pm-7:04 pm

2 stops30h 57m

$319

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Indiana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Indiana?

The cheapest month to fly to Indiana from Des Moines is in September. Flight prices, which tend to average around $251, are often lower during this time because this is during the off-season. The month of July is another great option to travel to Indiana, with average flight prices from Des Moines averaging around $259.

What is the cheapest day to depart on your flight to Indiana?

Our data shows that Saturday is the least expensive day to fly to Indiana. Tickets to fly out on this day can be as low as $994. On the other hand, Wednesday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,408.

Can stopping save me money on Des Moines to Indiana flights?

You could potentially save up to 52% on your flight if you consider stops on a Des Moines to Indiana flight.

Cheap Des Moines to Indiana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Indiana

Fastest flight time	1h 20m
Direct flights	Every day
Airports in Indiana	94 airports

The fastest flight from Des Moines to Indiana takes 1h 20m

Direct flights go from Des Moines to Indiana every day.

There are 94 airports in Indiana. From Des Moines there are direct flights to Chicago O'Hare Intl (ORD), Chicago Midway (MDW).

Search flight deals

When did momondo last update prices for flights from Des Moines Airport to Indiana?
Prices for flights from Des Moines Airport to Indiana refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Indiana?
There are 3 operators available for flights from Des Moines Airport to Indiana as of February 2026.
How old do you have to be to fly from Des Moines Airport to Indiana?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Indiana.
What documentation or ID do you need to fly to Indiana?
The necessary travel and health documents for your Indiana trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Indiana

Compare and see reviews for airlines that fly from Des Moines to Indiana with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $179	Free Cancellation	Rating 7.9 8,178 reviews	Search Delta flights
United Airlines	PriceFrom $196	Free Cancellation	Rating 7.4 9,269 reviews	Search United Airlines flights
American Airlines	PriceFrom $196	Free Cancellation	Rating 7.2 11,262 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Indiana?

It is quick and easy to find Des Moines to Indiana flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Indiana that suits you.

Can I find flights from Des Moines to Indiana with flexible booking policies on momondo?

Yes. All flights to Indiana from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Indiana?

Once all potential Des Moines to Indiana flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Indiana right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Indiana from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.