How many flights depart from Des Moines to Indiana on average per week?

229 flights are operational weekly from Des Moines to Indiana as of July 2026. The most popular departure day for this route is Tue, with 21% of flights per week taking off on this day.

What airlines fly to Indiana?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Indiana from Des Moines according to our data. United Airlines is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Indiana. Keep in mind that there are 3 different airlines that fly to Indiana on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to Indiana?

Allegiant Air, Southwest, and United Airlines are the most popular carriers operating from Des Moines to Indiana

When did momondo last update prices for flights from Des Moines Airport to Indiana?

Prices for flights from Des Moines Airport to Indiana refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Indiana?

There are 3 operators available for flights from Des Moines Airport to Indiana as of July 2026.

How old do you have to be to fly from Des Moines Airport to Indiana?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Indiana.

What documentation or ID do you need to fly to Indiana?

The necessary travel and health documents for your Indiana trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$101 Cheap Flights from Des Moines to Indiana in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Indiana

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:58 pm - 7:29 am

DSM

ORD

17h 31m

1 stop

7:25 am - 7:57 pm

ORD

DSM

12h 32m

1 stop

$207Multiple Airlines

Sun, Sep 6 - Thu, Sep 10

1:58 pm - 1:30 pm

DSM

ORD

23h 32m

1 stop

7:25 am - 7:57 pm

ORD

DSM

12h 32m

1 stop

$226Multiple Airlines

Thu, Sep 10 - Thu, Sep 17

1:58 pm - 1:30 pm

DSM

ORD

23h 32m

1 stop

7:25 am - 7:57 pm

ORD

DSM

12h 32m

1 stop

$230Multiple Airlines

Thu, Sep 10 - Thu, Sep 17

7:52 pm - 9:30 pm

DSM

ORD

1h 38mnonstop

7:15 am - 8:54 am

ORD

DSM

1h 39mnonstop

$236American Airlines

Mon, Oct 5 - Thu, Oct 15

7:58 pm - 9:47 pm

DSM

ORD

1h 49mnonstop

3:50 pm - 5:26 pm

ORD

DSM

1h 36mnonstop

$236American Airlines

Thu, Sep 10 - Thu, Sep 17

7:49 pm - 9:37 pm

DSM

ORD

1h 48mnonstop

8:26 am - 9:56 am

ORD

DSM

1h 30mnonstop

$236American Airlines

Thu, Aug 20 - Mon, Aug 24

11:32 am - 1:15 pm

DSM

ORD

1h 43mnonstop

10:45 am - 12:20 pm

ORD

DSM

1h 35mnonstop

$237United Airlines

Thu, Aug 20 - Mon, Aug 24

11:36 am - 1:15 pm

DSM

ORD

1h 39mnonstop

10:00 pm - 11:35 pm

ORD

DSM

1h 35mnonstop

$237United Airlines

Thu, Sep 24 - Mon, Sep 28

2:46 pm - 6:19 pm

DSM

MDW

3h 33m

1 stop

9:59 am - 4:48 pm

MDW

DSM

6h 49m

1 stop

$257Delta

Mon, Sep 21 - Tue, Sep 22

6:00 am - 11:31 am

DSM

IND

4h 31m

1 stop

12:26 pm - 4:48 pm

IND

DSM

5h 22m

1 stop

$273Delta

Thu, Sep 17 - Wed, Sep 23

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

American Airlines flights from Des Moines to Indiana

Our best American Airlines deals on Des Moines to Indiana flight tickets

American Airlines

Sep 10

DSM7:58 pmDes Moines

1h 49m

ORD9:47 pmChicago O'Hare Intl

Sep 17

ORD3:50 pmChicago O'Hare Intl

1h 36m

DSM5:26 pmDes Moines

$238

American Airlines

Sep 8

DSM6:55 amDes Moines

1h 50m

ORD8:45 amChicago O'Hare Intl

Sep 15

ORD6:59 amChicago O'Hare Intl

1h 40m

DSM8:39 amDes Moines

$239

American Airlines

Aug 28

DSM7:49 pmDes Moines

1h 48m

ORD9:37 pmChicago O'Hare Intl

Aug 29

ORD11:54 amChicago O'Hare Intl

1h 31m

DSM1:25 pmDes Moines

$269

United Airlines flights from Des Moines to Indiana

Our best United Airlines deals on Des Moines to Indiana flight tickets

United Airlines

Aug 29

DSM6:00 amDes Moines

1h 36m

ORD7:36 amChicago O'Hare Intl

Aug 29

ORD7:55 pmChicago O'Hare Intl

1h 28m

DSM9:23 pmDes Moines

$237

United Airlines

Oct 26

DSM8:00 amDes Moines

1h 40m

ORD9:40 amChicago O'Hare Intl

Oct 30

ORD9:25 pmChicago O'Hare Intl

1h 25m

DSM10:50 pmDes Moines

$242

United Airlines

Aug 18

DSM3:20 pmDes Moines

5h 40m

1 stop

IND10:00 pmIndianapolis

Aug 29

IND2:00 pmIndianapolis

4h 28m

1 stop

DSM5:28 pmDes Moines

$279

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Sun 9/6

1:58 pm-7:29 am

1 stop17h 31m

Chicago O'Hare Intl

Thu 9/10

7:25 am-7:57 pm

1 stop12h 32m

$207

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Thu 9/10

1:58 pm-1:30 pm

1 stop23h 32m

Chicago O'Hare Intl

Thu 9/17

7:25 am-7:57 pm

1 stop12h 32m

$226

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Thu 9/10

1:58 pm-1:30 pm

1 stop23h 32m

Chicago O'Hare Intl

Thu 9/17

7:25 am-7:57 pm

1 stop12h 32m

$230

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Mon 10/5

7:52 pm-9:30 pm

Nonstop1h 38m

Chicago O'Hare Intl

Thu 10/15

7:15 am-8:54 am

Nonstop1h 39m

$236

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Thu 9/10

7:58 pm-9:47 pm

Nonstop1h 49m

Chicago O'Hare Intl

Thu 9/17

3:50 pm-5:26 pm

Nonstop1h 36m

$236

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Thu 8/20

7:49 pm-9:37 pm

Nonstop1h 48m

Chicago O'Hare Intl

Mon 8/24

8:26 am-9:56 am

Nonstop1h 30m

$236

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Thu 8/20

11:32 am-1:15 pm

Nonstop1h 43m

Chicago O'Hare Intl

Mon 8/24

10:45 am-12:20 pm

Nonstop1h 35m

$237

Quickest round-trip

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Thu 9/24

11:36 am-1:15 pm

Nonstop1h 39m

Chicago O'Hare Intl

Mon 9/28

10:00 pm-11:35 pm

Nonstop1h 35m

$237

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Mon 9/21

2:46 pm-6:19 pm

1 stop3h 33m

Chicago Midway

Tue 9/22

9:59 am-4:48 pm

1 stop6h 49m

$257

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 9/17

6:00 am-11:31 am

1 stop4h 31m

Indianapolis

Wed 9/23

12:26 pm-4:48 pm

1 stop5h 22m

$273

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Indiana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Indiana?

The cheapest month to fly to Indiana from Des Moines is in December. Flight prices, which tend to average around $308, are often lower during this time because this is during the off-season. The month of February is another great option to travel to Indiana, with average flight prices from Des Moines averaging around $308.

Can stopping save me money on Des Moines to Indiana flights?

You could potentially save up to 12% on your flight if you consider stops on a Des Moines to Indiana flight.

Cheap Des Moines to Indiana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Indiana

Fastest flight time	1h 20m
Direct flights	Every day
Airports in Indiana	94 airports

The fastest flight from Des Moines to Indiana takes 1h 20m

Direct flights go from Des Moines to Indiana every day.

There are 94 airports in Indiana. From Des Moines there are direct flights to Chicago O'Hare Intl (ORD), Chicago Midway (MDW).

Search flight deals

Frequently asked questions about flying from Des Moines to Indiana

When did momondo last update prices for flights from Des Moines Airport to Indiana?
Prices for flights from Des Moines Airport to Indiana refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Indiana?
There are 3 operators available for flights from Des Moines Airport to Indiana as of July 2026.
How old do you have to be to fly from Des Moines Airport to Indiana?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Indiana.
What documentation or ID do you need to fly to Indiana?
The necessary travel and health documents for your Indiana trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Indiana

Compare and see reviews for airlines that fly from Des Moines to Indiana with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $216	Free Cancellation	Rating 7.8 8,482 reviews	Search Delta flights
American Airlines	PriceFrom $254	Free Cancellation	Rating 7.1 11,839 reviews	Search American Airlines flights
United Airlines	PriceFrom $272	Free Cancellation	Rating 7.4 10,046 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Indiana?

It is quick and easy to find Des Moines to Indiana flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Indiana that suits you.

Can I find flights from Des Moines to Indiana with flexible booking policies on momondo?

Yes. All flights to Indiana from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Indiana?

Once all potential Des Moines to Indiana flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Indiana right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Indiana from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.