What airlines fly to Indiana?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Indiana from Des Moines according to our data. United Airlines is the first choice among our users, with 55% of people opting to fly with this airline when traveling to Indiana. Keep in mind that there are 3 different airlines that fly to Indiana on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to Indiana?

Delta, American Airlines, and Southwest are the most popular carriers operating from Des Moines to Indiana

When did momondo last update prices for flights from Des Moines Airport to Indiana?

Prices for flights from Des Moines Airport to Indiana refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Indiana?

There are 3 operators available for flights from Des Moines Airport to Indiana as of September 2026.

How old do you have to be to fly from Des Moines Airport to Indiana?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Indiana.

What documentation or ID do you need to fly to Indiana?

The necessary travel and health documents for your Indiana trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$102 Cheap Flights from Des Moines to Indiana in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Indiana

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:26 pm - 12:38 amDSM Des Moines-IND Indianapolis

4h 12m1 stop Chicago O'Hare Intl

9:04 pm - 12:19 amIND Indianapolis-DSM Des Moines

4h 15m1 stop Chicago O'Hare Intl

$279American Airlines

Wed, Nov 18 - Mon, Nov 23

6:00 am - 11:32 amDSM Des Moines-IND Indianapolis

4h 32m1 stop Detroit Metropolitan Wayne County

12:12 pm - 4:55 pmIND Indianapolis-DSM Des Moines

5h 43m1 stop Detroit Metropolitan Wayne County

$279Delta

Tue, Oct 20 - Tue, Oct 27

6:45 pm - 11:47 pmDSM Des Moines-IND Indianapolis

4h 02m1 stop Chicago O'Hare Intl

3:11 pm - 7:16 pmIND Indianapolis-DSM Des Moines

5h 05m1 stop Chicago O'Hare Intl

$279United Airlines

Wed, Nov 18 - Mon, Nov 23

11:23 am - 4:23 pmDSM Des Moines-IND Indianapolis

4h 00m1 stop Chicago O'Hare Intl

4:30 pm - 9:55 pmIND Indianapolis-DSM Des Moines

6h 25m1 stop Chicago O'Hare Intl

$279United Airlines

Wed, Nov 18 - Mon, Nov 23

10:57 am - 5:55 pmDSM Des Moines-IND Indianapolis

5h 58m1 stop Minneapolis St Paul

7:00 am - 10:11 amIND Indianapolis-DSM Des Moines

4h 11m1 stop Minneapolis St Paul

$279Delta

Tue, Oct 27 - Thu, Oct 29

6:20 am - 2:15 pmDSM Des Moines-IND Indianapolis

6h 55m1 stop Detroit Metropolitan Wayne County

6:15 pm - 9:24 pmIND Indianapolis-DSM Des Moines

4h 09m1 stop Minneapolis St Paul

$279Delta

Thu, Jan 14 - Mon, Jan 18

5:35 am - 1:55 pmDSM Des Moines-IND Indianapolis

7h 20m2 stops Chicago Midway Nashville Intl

5:55 pm - 11:15 pmIND Indianapolis-DSM Des Moines

6h 20m1 stop Chicago Midway

$284Southwest

Tue, Oct 27 - Thu, Oct 29

6:00 am - 5:30 pmDSM Des Moines-IND Indianapolis

10h 30m2 stops Chicago Midway Atlanta Hartsfield-Jackson

2:55 pm - 10:05 pmIND Indianapolis-DSM Des Moines

8h 10m1 stop Denver Intl

$284Southwest

Wed, Nov 4 - Thu, Nov 5

5:39 am - 12:08 pmDSM Des Moines-IND Indianapolis

5h 29m1 stop Chicago O'Hare Intl

5:36 am - 8:46 amIND Indianapolis-DSM Des Moines

4h 10m1 stop Chicago O'Hare Intl

$318American Airlines

Sun, Nov 1 - Wed, Nov 4

7:26 pm - 12:38 amDSM Des Moines-IND Indianapolis

4h 12m1 stop Chicago O'Hare Intl

1:07 pm - 6:56 pmIND Indianapolis-DSM Des Moines

6h 49m1 stop Chicago O'Hare Intl

$318American Airlines

Sun, Nov 1 - Wed, Nov 4

Cheap last minute flights

Enter your travel dates to find the best prices.

11:29 am - 8:01 pmDSM Des Moines-IND Indianapolis

7h 32m1 stop Denver Intl

8:56 pm - 7:33 pmIND Indianapolis-DSM Des Moines

23h 37m1 stop Denver Intl

$440Frontier

Thu, Sep 24 - Sun, Sep 27

8:30 pm - 3:17 pmDSM Des Moines-IND Indianapolis

17h 47m1 stop Denver Intl

8:56 pm - 7:33 pmIND Indianapolis-DSM Des Moines

23h 37m1 stop Denver Intl

$440Frontier

Fri, Sep 25 - Sun, Sep 27

6:55 pm - 11:59 pmDSM Des Moines-LAF Lafayette Purdue University

4h 04m1 stop Chicago O'Hare Intl

5:45 am - 10:31 amLAF Lafayette Purdue University-DSM Des Moines

5h 46m1 stop Chicago O'Hare Intl

$494United Airlines

Thu, Sep 24 - Mon, Sep 28

6:00 am - 10:57 amDSM Des Moines-SBN South Bend/Michiana

3h 57m1 stop Chicago O'Hare Intl

7:40 pm - 11:35 pmSBN South Bend/Michiana-DSM Des Moines

4h 55m1 stop Chicago O'Hare Intl

$499United Airlines

Fri, Sep 25 - Sun, Sep 27

6:55 pm - 11:59 pmDSM Des Moines-LAF Lafayette Purdue University

4h 04m1 stop Chicago O'Hare Intl

5:45 am - 10:31 amLAF Lafayette Purdue University-DSM Des Moines

5h 46m1 stop Chicago O'Hare Intl

$530United Airlines

Fri, Sep 25 - Mon, Sep 28

9:59 am - 7:45 pmDSM Des Moines-IND Indianapolis

8h 46m1 stop Orlando Sanford Intl

1:25 pm - 2:15 pmIND Indianapolis-DSM Des Moines

25h 50m1 stop Punta Gorda

$659Allegiant Air

Fri, Sep 25 - Sat, Sep 26

1:30 pm - 9:04 pmDSM Des Moines-IND Indianapolis

6h 34m1 stop Charlotte Douglas

8:52 pm - 12:04 amIND Indianapolis-DSM Des Moines

4h 12m1 stop Chicago O'Hare Intl

$667American Airlines

Mon, Sep 28 - Tue, Sep 29

4:14 pm - 10:19 pmDSM Des Moines-IND Indianapolis

5h 05m1 stop Dallas/Fort Worth

6:00 am - 11:12 amIND Indianapolis-DSM Des Moines

6h 12m1 stop Dallas/Fort Worth

$667American Airlines

Fri, Sep 25 - Sun, Sep 27

4:14 pm - 10:19 pmDSM Des Moines-IND Indianapolis

5h 05m1 stop Dallas/Fort Worth

8:53 pm - 12:04 amIND Indianapolis-DSM Des Moines

4h 11m1 stop Chicago O'Hare Intl

$667American Airlines

Tue, Sep 29 - Thu, Oct 1

5:59 pm - 11:05 pmDSM Des Moines-IND Indianapolis

4h 06m1 stop Minneapolis St Paul

2:35 pm - 6:09 pmIND Indianapolis-DSM Des Moines

4h 34m1 stop Atlanta Hartsfield-Jackson

$797Delta

Thu, Sep 24 - Mon, Sep 28

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Southwest flights from Des Moines to Indiana

Our best Southwest deals on Des Moines to Indiana flight tickets

Southwest

Oct 27

DSM5:35 amDes Moines

7h 20m

2 stops

IND1:55 pmIndianapolis

Oct 29

IND5:55 pmIndianapolis

6h 20m

1 stop

DSM11:15 pmDes Moines

$284

Southwest

Nov 4

DSM6:00 amDes Moines

10h 30m

2 stops

IND5:30 pmIndianapolis

Nov 5

IND2:25 pmIndianapolis

9h 40m

2 stops

DSM11:05 pmDes Moines

$289

Southwest

Nov 18

DSM6:00 amDes Moines

10h 30m

2 stops

IND5:30 pmIndianapolis

Nov 23

IND5:30 pmIndianapolis

6h 35m

1 stop

DSM11:05 pmDes Moines

$302

Delta flights from Des Moines to Indiana

Our best Delta deals on Des Moines to Indiana flight tickets

Delta

Oct 23

DSM5:50 pmDes Moines

5h 15m

1 stop

IND12:05 amIndianapolis

Oct 26

IND4:59 pmIndianapolis

4h 41m

1 stop

DSM8:40 pmDes Moines

$297

Delta

Oct 23

DSM5:50 pmDes Moines

5h 15m

1 stop

IND12:05 amIndianapolis

Oct 26

IND4:59 pmIndianapolis

4h 41m

1 stop

DSM8:40 pmDes Moines

$315

Delta

Nov 1

DSM6:00 amDes Moines

4h 32m

1 stop

IND11:32 amIndianapolis

Nov 4

IND12:12 pmIndianapolis

5h 43m

1 stop

DSM4:55 pmDes Moines

$318

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

Des MoinesIndianapolis

DSM Des Moines - IND Indianapolis

DSMIND

Des Moines

Wed 11/18

7:26 pm-12:38 am

1 stop4h 12m

Indianapolis

Mon 11/23

9:04 pm-12:19 am

1 stop4h 15m

$279

Des MoinesIndianapolis

DSM Des Moines - IND Indianapolis

DSMIND

Des Moines

Tue 10/20

6:00 am-11:32 am

1 stop4h 32m

Indianapolis

Tue 10/27

12:12 pm-4:55 pm

1 stop5h 43m

$279

Des MoinesIndianapolis

DSM Des Moines - IND Indianapolis

DSMIND

Des Moines

Wed 11/18

6:45 pm-11:47 pm

1 stop4h 02m

Indianapolis

Mon 11/23

3:11 pm-7:16 pm

1 stop5h 05m

$279

Des MoinesIndianapolis

DSM Des Moines - IND Indianapolis

DSMIND

Des Moines

Wed 11/18

11:23 am-4:23 pm

1 stop4h 00m

Indianapolis

Mon 11/23

4:30 pm-9:55 pm

1 stop6h 25m

$279

Des MoinesIndianapolis

DSM Des Moines - IND Indianapolis

DSMIND

Des Moines

Tue 10/27

10:57 am-5:55 pm

1 stop5h 58m

Indianapolis

Thu 10/29

7:00 am-10:11 am

1 stop4h 11m

$279

Des MoinesIndianapolis

DSM Des Moines - IND Indianapolis

DSMIND

Des Moines

Thu 1/14

6:20 am-2:15 pm

1 stop6h 55m

Indianapolis

Mon 1/18

6:15 pm-9:24 pm

1 stop4h 09m

$279

Des MoinesIndianapolis

DSM Des Moines - IND Indianapolis

DSMIND

Des Moines

Tue 10/27

5:35 am-1:55 pm

2 stops7h 20m

Indianapolis

Thu 10/29

5:55 pm-11:15 pm

1 stop6h 20m

$284

Des MoinesIndianapolis

DSM Des Moines - IND Indianapolis

DSMIND

Des Moines

Wed 11/4

6:00 am-5:30 pm

2 stops10h 30m

Indianapolis

Thu 11/5

2:55 pm-10:05 pm

1 stop8h 10m

$284

Des MoinesIndianapolis

DSM Des Moines - IND Indianapolis

DSMIND

Des Moines

Sun 11/1

5:39 am-12:08 pm

1 stop5h 29m

Indianapolis

Wed 11/4

5:36 am-8:46 am

1 stop4h 10m

$318

Des MoinesIndianapolis

DSM Des Moines - IND Indianapolis

DSMIND

Des Moines

Sun 11/1

7:26 pm-12:38 am

1 stop4h 12m

Indianapolis

Wed 11/4

1:07 pm-6:56 pm

1 stop6h 49m

$318

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Indiana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Indiana?

The cheapest month to fly to Indiana from Des Moines is in December. Flight prices, which tend to average around $308, are often lower during this time because this is during the off-season. The month of February is another great option to travel to Indiana, with average flight prices from Des Moines averaging around $308.

Can stopping save me money on Des Moines to Indiana flights?

You could potentially save up to 18% on your flight if you consider stops on a Des Moines to Indiana flight.

Cheap Des Moines to Indiana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Indiana

Best Price Found	$102
Fastest flight time	1h 20m
Direct flights	None

The best one-way flight to Indiana from Des Moines in the past 72 hours is $102. The best round-trip flight deal from Des Moines to Indiana found on momondo in the last 72 hours is $279.

The fastest flight from Des Moines to Indiana takes 1h 20m

There are no direct flights from Des Moines to Indiana. There are no popular flight routes from Des Moines to Indiana.

Search flight deals

Frequently asked questions about flying from Des Moines to Indiana

When did momondo last update prices for flights from Des Moines Airport to Indiana?
Prices for flights from Des Moines Airport to Indiana refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Indiana?
There are 3 operators available for flights from Des Moines Airport to Indiana as of September 2026.
How old do you have to be to fly from Des Moines Airport to Indiana?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Indiana.
What documentation or ID do you need to fly to Indiana?
The necessary travel and health documents for your Indiana trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Indiana

Compare and see reviews for airlines that fly from Des Moines to Indiana with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $272	Free Cancellation	Rating 7.4 10,226 reviews	Search United Airlines flights
Delta	PriceFrom $272	Free Cancellation	Rating 7.8 8,591 reviews	Search Delta flights
American Airlines	PriceFrom $276	Free Cancellation	Rating 7.0 12,075 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Indiana?

It is quick and easy to find Des Moines to Indiana flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Indiana that suits you.

Can I find flights from Des Moines to Indiana with flexible booking policies on momondo?

Yes. All flights to Indiana from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Indiana?

Once all potential Des Moines to Indiana flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Indiana right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Indiana from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.