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Cheap flights from Des Moines to Florida from $45

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Florida departing on 3/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Florida

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
3:32 pm - 7:46 pm
DSM
-
FLL
3h 14mnonstop
Allegiant Air Logo
8:36 pm - 11:12 pm
FLL
-
DSM
3h 36mnonstop
$100Allegiant Air
Sun, Feb 15 - Thu, Feb 19
Allegiant Air Logo
3:22 pm - 7:23 pm
DSM
-
PGD
3h 01mnonstop
Allegiant Air Logo
8:48 pm - 11:07 pm
PGD
-
DSM
3h 19mnonstop
$103Allegiant Air
Sat, Jan 3 - Thu, Jan 22
Southwest Logo
6:10 am - 5:50 pm
DSM
-
MIA
10h 40m1 stop
Southwest Logo
6:25 am - 11:30 am
MIA
-
DSM
6h 05m1 stop
$213Southwest
Sat, Feb 28 - Sat, Mar 7
Delta Logo
12:25 pm - 11:13 pm
DSM
-
PNS
10h 48m2 stops
Delta Logo
6:00 am - 10:41 am
PNS
-
DSM
4h 41m1 stop
$222Delta
Sat, Jan 17 - Tue, Jan 20
Delta Logo
5:16 pm - 12:51 am
DSM
-
MIA
6h 35m1 stop
Delta Logo
10:29 am - 4:28 pm
MIA
-
DSM
6h 59m1 stop
$237Delta
Tue, Feb 3 - Tue, Feb 10
Southwest Logo
8:35 am - 7:10 pm
DSM
-
SRQ
9h 35m1 stop
Southwest Logo
7:55 am - 11:25 am
SRQ
-
DSM
4h 30m1 stop
$237Southwest
Tue, Jan 20 - Tue, Jan 27
United Airlines Logo
5:30 am - 3:08 pm
DSM
-
SRQ
8h 38m1 stop
United Airlines Logo
9:15 am - 8:34 pm
SRQ
-
DSM
12h 19m2 stops
$242United Airlines
Sat, Jan 10 - Sat, Jan 17
United Airlines Logo
8:00 am - 5:15 pm
DSM
-
MIA
8h 15m1 stop
United Airlines Logo
6:20 am - 4:28 pm
MIA
-
DSM
11h 08m2 stops
$242United Airlines
Wed, Jan 21 - Sat, Jan 24
American Airlines Logo
7:10 am - 2:17 pm
DSM
-
MIA
6h 07m1 stop
American Airlines Logo
8:39 pm - 11:29 pm
MIA
-
DSM
3h 50mnonstop
$247American Airlines
Wed, Feb 4 - Wed, Feb 11
American Airlines Logo
6:07 am - 2:17 pm
DSM
-
MIA
7h 10m1 stop
American Airlines Logo
8:39 pm - 11:29 pm
MIA
-
DSM
3h 50mnonstop
$248American Airlines
Wed, Feb 4 - Wed, Feb 11

Southwest flights from Des Moines to Florida

Our best Southwest deals on Des Moines to Florida flight tickets
Southwest
Feb 28
DSM6:10 amDes Moines
10h 40m
1 stop
MIA5:50 pmMiami
Mar 7
MIA6:25 amMiami
6h 05m
1 stop
DSM11:30 amDes Moines
$213
Find similar
Southwest
Jan 20
DSM8:35 amDes Moines
9h 35m
1 stop
SRQ7:10 pmSarasota Bradenton Intl
Jan 27
SRQ7:55 amSarasota Bradenton Intl
4h 30m
1 stop
DSM11:25 amDes Moines
$237
Find similar
Southwest
Feb 2
DSM3:20 pmDes Moines
4h 50m
1 stop
TPA9:10 pmTampa
Feb 5
TPA7:15 amTampa
4h 35m
1 stop
DSM10:50 amDes Moines
$261
Find similar

American Airlines flights from Des Moines to Florida

Our best American Airlines deals on Des Moines to Florida flight tickets
American Airlines
Feb 3
DSM11:42 amDes Moines
6h 07m
1 stop
TPA6:49 pmTampa
Feb 10
TPA5:14 pmTampa
5h 57m
1 stop
DSM10:11 pmDes Moines
$235
Find similar
American Airlines
Feb 4
DSM11:35 amDes Moines
8h 24m
1 stop
FLL8:59 pmFort Lauderdale
Feb 11
FLL5:47 pmFort Lauderdale
6h 36m
1 stop
DSM11:23 pmDes Moines
$237
Find similar
American Airlines
Feb 4
DSM7:10 amDes Moines
6h 07m
1 stop
MIA2:17 pmMiami
Feb 11
MIA8:39 pmMiami
3h 50m
DSM11:29 pmDes Moines
$247
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Des Moines to Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesFort Lauderdale

DSM - FLL

DSMFLL

Des Moines

Sun 2/15

3:32 pm-7:46 pm

Nonstop3h 14m

Fort Lauderdale

Thu 2/19

8:36 pm-11:12 pm

Nonstop3h 36m

$100

Des MoinesPunta Gorda

DSM - PGD

DSMPGD

Des Moines

Sat 1/3

3:22 pm-7:23 pm

Nonstop3h 01m

Punta Gorda

Thu 1/22

8:48 pm-11:07 pm

Nonstop3h 19m

$103

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Sat 2/28

6:10 am-5:50 pm

1 stop10h 40m

Miami

Sat 3/7

6:25 am-11:30 am

1 stop6h 05m

$213

Des MoinesPensacola

DSM - PNS

DSMPNS

Des Moines

Sat 1/17

12:25 pm-11:13 pm

2 stops10h 48m

Pensacola

Tue 1/20

6:00 am-10:41 am

1 stop4h 41m

$222

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 2/3

5:16 pm-12:51 am

1 stop6h 35m

Miami

Tue 2/10

10:29 am-4:28 pm

1 stop6h 59m

$237

Des MoinesSarasota

DSM - SRQ

DSMSRQ

Des Moines

Tue 1/20

8:35 am-7:10 pm

1 stop9h 35m

Sarasota Bradenton Intl

Tue 1/27

7:55 am-11:25 am

1 stop4h 30m

$237

Des MoinesSarasota

DSM - SRQ

DSMSRQ

Des Moines

Sat 1/10

5:30 am-3:08 pm

1 stop8h 38m

Sarasota Bradenton Intl

Sat 1/17

9:15 am-8:34 pm

2 stops12h 19m

$242

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Wed 1/21

8:00 am-5:15 pm

1 stop8h 15m

Miami

Sat 1/24

6:20 am-4:28 pm

2 stops11h 08m

$242

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Wed 2/4

7:10 am-2:17 pm

1 stop6h 07m

Miami

Wed 2/11

8:39 pm-11:29 pm

Nonstop3h 50m

$247

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Wed 2/4

6:07 am-2:17 pm

1 stop7h 10m

Miami

Wed 2/11

8:39 pm-11:29 pm

Nonstop3h 50m

$248

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Florida from

How to get the cheapest flight ticket from Des Moines to Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida?

In general, June is the cheapest month to fly from Des Moines to Florida. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $321. If you’re not able to fly to Florida in June, then August is your next best option. Flight prices from Des Moines to Florida during August average around $355.

What is the cheapest day to depart on your flight to Florida?

On average, the least expensive day to fly to Florida from Des Moines is on a Thursday. momondo users have found tickets for Thursday departures for as low as $547. However, this price may fluctuate depending on the airline, the season, and holidays. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Florida on Friday is $687.

What is the cheapest time of day to depart on your flight to Florida?

Flying to Florida from Des Moines in the evening is the least expensive time of day to depart. momondo users have found prices as low as $278 when looking at flights departing in the evening. Flights to Florida are more costly in the morning, with an average ticket price of $623. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Des Moines to Florida flight route?

Fly from Des Moines to Fort Myers SW Florida Intl for the best Des Moines - Florida flight prices

How far in advance should I book a flight to Florida?

You are more likely to see cheaper flights to Florida from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida for around $412 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida from Des Moines for as low as $331 on momondo.

What cabin class options are available on Des Moines to Florida flights?

There are 2 cabin classes available to choose from on Des Moines to Florida flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to Florida flights?

No. A direct flight is the cheapest option for a flight between Des Moines to Florida.

Cheap Des Moines to Florida flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Florida

Best Price Found

$45

Fastest flight time

2h 18m

Direct flights

Every day

Airports in Florida

256 airports
The best one-way flight to Florida from Des Moines in the past 72 hours is $45. The best round-trip flight deal from Des Moines to Florida found on momondo in the last 72 hours is $130.
The fastest flight from Des Moines to Florida takes 2h 18m
Direct flights go from Des Moines to Florida every day.
There are 256 airports in Florida. From Des Moines there are direct flights to Sarasota Bradenton Intl (SRQ), Orlando (MCO), Punta Gorda (PGD), Orlando Sanford Intl (SFB).
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Florida?

    Prices for flights from Des Moines Airport to Florida refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Florida?

  • How old do you have to be to fly from Des Moines Airport to Florida?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Florida.

  • What documentation or ID do you need to fly to Florida?

    The necessary travel and health documents for your Florida trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Des Moines to Florida?

Best airlines flying from Des Moines to Florida

Compare and see reviews for airlines that fly from Des Moines to Florida with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $78Free CancellationRating
7.2
701 reviews
Search Allegiant Air flights
FrontierPriceFrom $118Free CancellationRating
5.8
3,075 reviews
Search Frontier flights
DeltaPriceFrom $213Free CancellationRating
7.9
8,014 reviews
Search Delta flights
American AirlinesPriceFrom $216Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
United AirlinesPriceFrom $226Free CancellationRating
7.4
9,105 reviews
Search United Airlines flights
SouthwestPriceFrom $228Free CancellationRating
8.0
4,253 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Florida?

Finding the right flight to Florida from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florida quick and easy, saving you time and money.

Can I find flights from Des Moines to Florida with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Florida flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Florida?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florida from Des Moines.

I’m not ready to book a flight from Des Moines to Florida right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Florida flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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