Cheap flights from Colorado to Indianapolis from $135

In general, October is the cheapest month to fly from Colorado to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $251. If you are unable to visit Indianapolis during the month of October, then departing from Colorado during the month February is also very affordable. Most momondo users find prices during this month for around $276.

Our data shows that Thursday is the least expensive day to fly to Indianapolis. Tickets to fly out on this day can be as low as $285. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Indianapolis on Monday is $421.

Flying to Indianapolis from Colorado in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $273 when looking at flights departing in the afternoon. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are $417 on average. Flights to Indianapolis from Colorado in the evening are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from Denver Intl to Indianapolis for the best Colorado - Indianapolis flight prices

You are more likely to see cheaper flights to Indianapolis from Colorado when booking weeks ahead of your departure date. In general, you can expect to find flights to Indianapolis for around $318 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Indianapolis from Colorado for as low as $227 on momondo.

There are 4 cabin classes available to choose from on Colorado to Indianapolis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Frontier, Southwest, and United Airlines are the most popular carriers operating from Colorado to Indianapolis

Frontier, United Airlines and Southwest are the top three most popular airlines that fly to Indianapolis from Colorado according to our data. Frontier is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Indianapolis. Keep in mind that there are 6 different airlines that fly to Indianapolis on a routine basis, so you have a few additional options to choose from.

As of August 2026, 6 flights take off from Colorado and land in Indianapolis each day. The most common flight departure time for this route is 3:00PM, with 55% of daily flights taking off in the afternoon.

As of August 2026, 44 flights take off from Colorado and land in Indianapolis each week. The most common flight departure day for this route is Sun, with 25% of weekly flights taking off on this day.