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Cheap flights from Cleveland to Florence from $444

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Florence departing on 5/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Find the cheapest flights from Cleveland to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:53 pm - 10:00 pm
CLE
-
FLO
6h 07m
1 stop
American Airlines Logo
5:05 am - 11:17 am
FLO
-
CLE
6h 12m
1 stop
$480American Airlines
mié., may. 27 - mié., jun. 3
American Airlines Logo
2:34 pm - 10:00 pm
CLE
-
FLO
7h 26m
2 stops
American Airlines Logo
5:05 am - 11:17 am
FLO
-
CLE
6h 12m
1 stop
$485American Airlines
mié., may. 27 - mié., jun. 3
American Airlines Logo
7:08 am - 2:10 pm
CLE
-
FLO
7h 02m
2 stops
American Airlines Logo
2:35 pm - 10:28 pm
FLO
-
CLE
7h 53m
2 stops
$491American Airlines
mié., may. 27 - mié., jun. 3
American Airlines Logo
10:52 am - 10:42 pm
CLE
-
FLO
11h 50m
2 stops
American Airlines Logo
5:20 am - 9:15 am
FLO
-
CLE
3h 55m
1 stop
$503American Airlines
mar., may. 12 - sáb., may. 16
American Airlines Logo
10:52 am - 10:42 pm
CLE
-
FLO
11h 50m
2 stops
American Airlines Logo
5:20 am - 3:21 pm
FLO
-
CLE
10h 01m
2 stops
$508American Airlines
mar., may. 12 - sáb., may. 16
American Airlines Logo
3:54 pm - 10:00 pm
CLE
-
FLO
6h 06m
1 stop
American Airlines Logo
5:05 am - 11:16 am
FLO
-
CLE
6h 11m
1 stop
$535American Airlines
vie., jun. 26 - lun., jun. 29
American Airlines Logo
8:10 am - 2:10 pm
CLE
-
FLO
6h 00m
1 stop
American Airlines Logo
5:05 am - 2:42 pm
FLO
-
CLE
9h 37m
2 stops
$540American Airlines
vie., jun. 26 - lun., jun. 29
American Airlines Logo
7:06 pm - 10:42 pm
CLE
-
FLO
3h 36m
1 stop
American Airlines Logo
4:16 pm - 9:37 pm
FLO
-
CLE
5h 21m
1 stop
$541American Airlines
mar., may. 12 - sáb., may. 16
American Airlines Logo
7:07 am - 2:10 pm
CLE
-
FLO
7h 03m
2 stops
American Airlines Logo
2:35 pm - 11:56 pm
FLO
-
CLE
9h 21m
2 stops
$545American Airlines
vie., jun. 26 - lun., jun. 29
American Airlines Logo
10:05 am - 3:50 pm
CLE
-
FLO
5h 45m
1 stop
American Airlines Logo
5:20 am - 9:15 am
FLO
-
CLE
3h 55m
1 stop
$619American Airlines
jue., may. 14 - lun., may. 18

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American Airlines flights from Cleveland to Florence, South Carolina

Our best American Airlines deals on Cleveland to Florence, South Carolina flight tickets
American Airlines
May 27
CLE3:53 pmCleveland Hopkins Intl
6h 07m
1 stop
FLO10:00 pmFlorence
Jun 3
FLO5:05 amFlorence
6h 12m
1 stop
CLE11:17 amCleveland Hopkins Intl
$480
American Airlines
May 27
CLE2:34 pmCleveland Hopkins Intl
7h 26m
2 stops
FLO10:00 pmFlorence
Jun 3
FLO5:05 amFlorence
6h 12m
1 stop
CLE11:17 amCleveland Hopkins Intl
$485
American Airlines
May 27
CLE7:08 amCleveland Hopkins Intl
7h 02m
2 stops
FLO2:10 pmFlorence
Jun 3
FLO2:35 pmFlorence
7h 53m
2 stops
CLE10:28 pmCleveland Hopkins Intl
$491

momondo Fare Finder

 
Customize your flight search to find flights from Cleveland to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated mayo 1, 2026.
Use the filters below to find and compare flights from Cleveland to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

mié. 5/27

3:53 pm-10:00 pm

1 stop6h 07m

Florence

mié. 6/3

5:05 am-11:17 am

1 stop6h 12m

$480

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

mié. 5/27

2:34 pm-10:00 pm

2 stops7h 26m

Florence

mié. 6/3

5:05 am-11:17 am

1 stop6h 12m

$485

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

mié. 5/27

7:08 am-2:10 pm

2 stops7h 02m

Florence

mié. 6/3

2:35 pm-10:28 pm

2 stops7h 53m

$491

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

mar. 5/12

10:52 am-10:42 pm

2 stops11h 50m

Florence

sáb. 5/16

5:20 am-9:15 am

1 stop3h 55m

$503

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

mar. 5/12

10:52 am-10:42 pm

2 stops11h 50m

Florence

sáb. 5/16

5:20 am-3:21 pm

2 stops10h 01m

$508

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

vie. 6/26

3:54 pm-10:00 pm

1 stop6h 06m

Florence

lun. 6/29

5:05 am-11:16 am

1 stop6h 11m

$535

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

vie. 6/26

8:10 am-2:10 pm

1 stop6h 00m

Florence

lun. 6/29

5:05 am-2:42 pm

2 stops9h 37m

$540
Quickest round-trip

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

mar. 5/12

7:06 pm-10:42 pm

1 stop3h 36m

Florence

sáb. 5/16

4:16 pm-9:37 pm

1 stop5h 21m

$541

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

vie. 6/26

7:07 am-2:10 pm

2 stops7h 03m

Florence

lun. 6/29

2:35 pm-11:56 pm

2 stops9h 21m

$545

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

jue. 5/14

10:05 am-3:50 pm

1 stop5h 45m

Florence

lun. 5/18

5:20 am-9:15 am

1 stop3h 55m

$619

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Cleveland to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Cleveland Hopkins Intl to Florence?

American Airlines is the most popular carrier operating from Cleveland Hopkins Intl to Florence

What airlines fly to Florence, South Carolina?

Breeze Airways, American Airlines and Allegiant Air are the top three most popular airlines that fly to Florence, South Carolina from Cleveland according to our data. Breeze Airways is the first choice among our users, with 37% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Cleveland to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Cleveland to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cleveland to Florence, South Carolina (CLE to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Florence, South Carolina

Fastest flight time

5h 45m

Direct flights

None
The fastest flight from Cleveland to Florence, South Carolina takes 5h 45m
There are no direct flights from Cleveland to Florence, South Carolina. There are no popular flight routes from Cleveland to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Cleveland to Florence, South Carolina

  • How far is Cleveland Hopkins Intl to Florence by plane?

    There are 515.1 mi between Cleveland Hopkins Intl and Florence. In terms of flight time, this usually takes a little over 5h 45m.

  • When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Florence Airport?

    Prices for flights from Cleveland Hopkins Intl Airport to Florence Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Cleveland Hopkins Intl Airport to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Cleveland Hopkins Intl Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington
Bennettsville
Lake City

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Cleveland.

Can I find flights from Cleveland to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Cleveland with this policy.

How can momondo help me find flights from Cleveland to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Cleveland to Florence.

I’m not ready to book a flight from Cleveland to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Cleveland to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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