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Cheap flights from Cleveland to Florence from $551

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Florence departing on 8/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Cleveland to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:39 pm - 10:59 pmCLE  Cleveland Hopkins Intl-FLO Florence
4h 20m1 stop Charlotte Douglas
American Airlines Logo
6:22 am - 11:58 amFLO  Florence-CLE Cleveland Hopkins Intl
5h 36m1 stop Charlotte Douglas
$551American Airlines
Tue, Aug 18 - Sat, Aug 22
American Airlines Logo
4:54 pm - 10:59 pmCLE  Cleveland Hopkins Intl-FLO Florence
6h 05m1 stop Charlotte Douglas
American Airlines Logo
6:22 am - 5:06 pmFLO  Florence-CLE Cleveland Hopkins Intl
10h 44m2 stops Charlotte Douglas New York John F Kennedy Intl
$624American Airlines
Tue, Aug 18 - Sat, Aug 22
American Airlines Logo
2:30 pm - 10:59 pmCLE  Cleveland Hopkins Intl-FLO Florence
8h 29m2 stops Washington, D.C. Reagan-National Charlotte Douglas
American Airlines Logo
6:22 am - 4:09 pmFLO  Florence-CLE Cleveland Hopkins Intl
9h 47m2 stops Charlotte Douglas Chicago O'Hare Intl
$705American Airlines
Tue, Aug 18 - Sat, Aug 22
American Airlines Logo
6:39 pm - 10:59 pmCLE  Cleveland Hopkins Intl-FLO Florence
4h 20m1 stop Charlotte Douglas
American Airlines Logo
3:22 pm - 9:00 pmFLO  Florence-CLE Cleveland Hopkins Intl
5h 38m1 stop Charlotte Douglas
$897American Airlines
Tue, Aug 18 - Wed, Aug 19
American Airlines Logo
6:00 am - 2:56 pmCLE  Cleveland Hopkins Intl-FLO Florence
8h 56m2 stops New York LaGuardia Charlotte Douglas
American Airlines Logo
6:22 am - 11:57 amFLO  Florence-CLE Cleveland Hopkins Intl
5h 35m1 stop Charlotte Douglas
$933American Airlines
Tue, Aug 18 - Wed, Aug 19
American Airlines Logo
5:15 am - 2:56 pmCLE  Cleveland Hopkins Intl-FLO Florence
9h 41m2 stops Chicago O'Hare Intl Charlotte Douglas
American Airlines Logo
6:22 am - 2:22 pmFLO  Florence-CLE Cleveland Hopkins Intl
8h 00m2 stops Charlotte Douglas New York John F Kennedy Intl
$970American Airlines
Tue, Aug 18 - Wed, Aug 19

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American Airlines flights from Cleveland to Florence, South Carolina

Our best American Airlines deals on Cleveland to Florence, South Carolina flight tickets
American Airlines
Aug 18
CLE6:39 pmCleveland Hopkins Intl
4h 20m
1 stop
FLO10:59 pmFlorence
Aug 22
FLO6:22 amFlorence
5h 36m
1 stop
CLE11:58 amCleveland Hopkins Intl
$551
American Airlines
Aug 18
CLE4:54 pmCleveland Hopkins Intl
6h 05m
1 stop
FLO10:59 pmFlorence
Aug 22
FLO6:22 amFlorence
10h 44m
2 stops
CLE5:06 pmCleveland Hopkins Intl
$624
American Airlines
Aug 15
CLE9:30 amCleveland Hopkins Intl
5h 26m
1 stop
FLO2:56 pmFlorence
Aug 22
FLO6:22 amFlorence
10h 44m
2 stops
CLE5:06 pmCleveland Hopkins Intl
$629

momondo Fare Finder

 
Customize your flight search to find flights from Cleveland to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Cleveland to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ClevelandFlorence

CLE Cleveland Hopkins Intl - FLO Florence

CLEFLO

Cleveland Hopkins Intl

Tue 8/18

6:39 pm-10:59 pm

1 stop4h 20m

Florence

Sat 8/22

6:22 am-11:58 am

1 stop5h 36m

$551

ClevelandFlorence

CLE Cleveland Hopkins Intl - FLO Florence

CLEFLO

Cleveland Hopkins Intl

Tue 8/18

4:54 pm-10:59 pm

1 stop6h 05m

Florence

Sat 8/22

6:22 am-5:06 pm

2 stops10h 44m

$624

ClevelandFlorence

CLE Cleveland Hopkins Intl - FLO Florence

CLEFLO

Cleveland Hopkins Intl

Tue 8/18

2:30 pm-10:59 pm

2 stops8h 29m

Florence

Sat 8/22

6:22 am-4:09 pm

2 stops9h 47m

$705

ClevelandFlorence

CLE Cleveland Hopkins Intl - FLO Florence

CLEFLO

Cleveland Hopkins Intl

Tue 8/18

6:39 pm-10:59 pm

1 stop4h 20m

Florence

Wed 8/19

3:22 pm-9:00 pm

1 stop5h 38m

$897

ClevelandFlorence

CLE Cleveland Hopkins Intl - FLO Florence

CLEFLO

Cleveland Hopkins Intl

Tue 8/18

6:00 am-2:56 pm

2 stops8h 56m

Florence

Wed 8/19

6:22 am-11:57 am

1 stop5h 35m

$933

ClevelandFlorence

CLE Cleveland Hopkins Intl - FLO Florence

CLEFLO

Cleveland Hopkins Intl

Tue 8/18

5:15 am-2:56 pm

2 stops9h 41m

Florence

Wed 8/19

6:22 am-2:22 pm

2 stops8h 00m

$970

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Cleveland to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

Breeze Airways, American Airlines and Allegiant Air are the top three most popular airlines that fly to Florence, South Carolina from Cleveland according to our data. Breeze Airways is the first choice among our users, with 38% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Cleveland to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Cleveland to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cleveland to Florence, South Carolina (CLE to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Florence, South Carolina

Fastest flight time

6h 05m

Direct flights

None
The fastest flight from Cleveland to Florence, South Carolina takes 6h 05m
There are no direct flights from Cleveland to Florence, South Carolina. There are no popular flight routes from Cleveland to Florence, South Carolina.
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Frequently asked questions about flying from Cleveland to Florence, South Carolina

  • How far is Cleveland Hopkins Intl to Florence by plane?

    There are 515.1 mi between Cleveland Hopkins Intl and Florence. In terms of flight time, this usually takes a little over 6h 05m.

  • When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Florence Airport?

    Prices for flights from Cleveland Hopkins Intl Airport to Florence Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Cleveland Hopkins Intl Airport to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Cleveland Hopkins Intl Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Cleveland.

Can I find flights from Cleveland to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Cleveland with this policy.

How can momondo help me find flights from Cleveland to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Cleveland to Florence.

I’m not ready to book a flight from Cleveland to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Cleveland to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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