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Cheap flights from Cleveland to Florence from $467

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Florence departing on 2/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Cleveland to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:33 am - 11:08 pm
CLE
-
FLO
12h 35m
2 stops
American Airlines Logo
5:16 am - 3:27 pm
FLO
-
CLE
10h 11m
2 stops
$467American Airlines
Tue, Feb 17 - Sat, Feb 21
American Airlines Logo
6:49 am - 5:21 pm
CLE
-
FLO
10h 32m
2 stops
American Airlines Logo
5:16 am - 9:04 am
FLO
-
CLE
3h 48m
1 stop
$478American Airlines
Tue, Feb 17 - Sat, Feb 21
American Airlines Logo
10:05 am - 3:50 pm
CLE
-
FLO
5h 45m
1 stop
American Airlines Logo
5:24 am - 9:15 am
FLO
-
CLE
3h 51m
1 stop
$495American Airlines
Thu, Apr 9 - Sun, Apr 12
American Airlines Logo
7:42 am - 3:50 pm
CLE
-
FLO
8h 08m
2 stops
American Airlines Logo
5:24 am - 9:15 am
FLO
-
CLE
3h 51m
1 stop
$500American Airlines
Thu, Apr 9 - Sun, Apr 12
American Airlines Logo
1:10 pm - 5:21 pm
CLE
-
FLO
4h 11m
1 stop
American Airlines Logo
6:25 pm - 10:10 pm
FLO
-
CLE
3h 45m
1 stop
$501American Airlines
Tue, Feb 17 - Sat, Feb 21
American Airlines Logo
2:02 pm - 11:53 pm
CLE
-
FLO
9h 51m
2 stops
American Airlines Logo
5:24 am - 1:18 pm
FLO
-
CLE
7h 54m
2 stops
$505American Airlines
Thu, Apr 9 - Sun, Apr 12
American Airlines Logo
6:49 am - 11:08 pm
CLE
-
FLO
16h 19m
2 stops
American Airlines Logo
5:24 am - 9:15 am
FLO
-
CLE
3h 51m
1 stop
$523American Airlines
Tue, Mar 31 - Sat, Apr 11
American Airlines Logo
10:56 am - 11:08 pm
CLE
-
FLO
12h 12m
2 stops
American Airlines Logo
5:24 am - 11:54 am
FLO
-
CLE
6h 30m
2 stops
$528American Airlines
Tue, Mar 31 - Sat, Apr 11
American Airlines Logo
5:55 pm - 11:08 pm
CLE
-
FLO
5h 13m
1 stop
American Airlines Logo
4:16 pm - 9:37 pm
FLO
-
CLE
5h 21m
1 stop
$531American Airlines
Tue, Mar 31 - Sat, Apr 11
American Airlines Logo
11:06 am - 5:21 pm
CLE
-
FLO
6h 15m
1 stop
American Airlines Logo
4:16 pm - 10:00 pm
FLO
-
CLE
5h 44m
1 stop
$555American Airlines
Tue, Mar 31 - Thu, Apr 9

American Airlines flights from Cleveland to Florence, South Carolina

Our best American Airlines deals on Cleveland to Florence, South Carolina flight tickets
American Airlines
Feb 17
CLE10:33 amCleveland Hopkins Intl
12h 35m
2 stops
FLO11:08 pmFlorence
Feb 21
FLO5:16 amFlorence
10h 11m
2 stops
CLE3:27 pmCleveland Hopkins Intl
$467
American Airlines
Feb 17
CLE6:49 amCleveland Hopkins Intl
10h 32m
2 stops
FLO5:21 pmFlorence
Feb 21
FLO5:16 amFlorence
3h 48m
1 stop
CLE9:04 amCleveland Hopkins Intl
$478
American Airlines
Apr 9
CLE10:05 amCleveland Hopkins Intl
5h 45m
1 stop
FLO3:50 pmFlorence
Apr 12
FLO5:24 amFlorence
3h 51m
1 stop
CLE9:15 amCleveland Hopkins Intl
$495

momondo Fare Finder

 
Customize your flight search to find flights from Cleveland to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Cleveland to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 2/17

10:33 am-11:08 pm

2 stops12h 35m

Florence

Sat 2/21

5:16 am-3:27 pm

2 stops10h 11m

$467

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 2/17

6:49 am-5:21 pm

2 stops10h 32m

Florence

Sat 2/21

5:16 am-9:04 am

1 stop3h 48m

$478

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Thu 4/9

10:05 am-3:50 pm

1 stop5h 45m

Florence

Sun 4/12

5:24 am-9:15 am

1 stop3h 51m

$495

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Thu 4/9

7:42 am-3:50 pm

2 stops8h 08m

Florence

Sun 4/12

5:24 am-9:15 am

1 stop3h 51m

$500

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 2/17

1:10 pm-5:21 pm

1 stop4h 11m

Florence

Sat 2/21

6:25 pm-10:10 pm

1 stop3h 45m

$501

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Thu 4/9

2:02 pm-11:53 pm

2 stops9h 51m

Florence

Sun 4/12

5:24 am-1:18 pm

2 stops7h 54m

$505

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 3/31

6:49 am-11:08 pm

2 stops16h 19m

Florence

Sat 4/11

5:24 am-9:15 am

1 stop3h 51m

$523

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 3/31

10:56 am-11:08 pm

2 stops12h 12m

Florence

Sat 4/11

5:24 am-11:54 am

2 stops6h 30m

$528

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 3/31

5:55 pm-11:08 pm

1 stop5h 13m

Florence

Sat 4/11

4:16 pm-9:37 pm

1 stop5h 21m

$531

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 3/31

11:06 am-5:21 pm

1 stop6h 15m

Florence

Thu 4/9

4:16 pm-10:00 pm

1 stop5h 44m

$555

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Cleveland to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

Breeze Airways, American Airlines and Spirit Airlines are the top three most popular airlines that fly to Florence, South Carolina from Cleveland according to our data. Breeze Airways is the first choice among our users, with 32% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Cleveland to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Cleveland to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cleveland to Florence, South Carolina (CLE to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Florence, South Carolina

Fastest flight time

5h 02m

Direct flights

None
The fastest flight from Cleveland to Florence, South Carolina takes 5h 02m
There are no direct flights from Cleveland to Florence, South Carolina. There are no popular flight routes from Cleveland to Florence, South Carolina.
Search flight deals

  • How far is Cleveland Hopkins Intl to Florence by plane?

    There are 515.1 mi between Cleveland Hopkins Intl and Florence. In terms of flight time, this usually takes a little over 5h 02m.

  • When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Florence Airport?

    Prices for flights from Cleveland Hopkins Intl Airport to Florence Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to Florence Airport?

  • How old do you have to be to fly from Cleveland Hopkins Intl Airport to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Cleveland Hopkins Intl Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Cleveland to Florence, South Carolina?

Best airlines flying from Cleveland to Florence, South Carolina

Compare and see reviews for airlines that fly from Cleveland to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $377Free CancellationRating
7.2
11,212 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Cleveland.

Can I find flights from Cleveland to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Cleveland with this policy.

How can momondo help me find flights from Cleveland to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Cleveland to Florence.

I’m not ready to book a flight from Cleveland to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Cleveland to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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