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Cheap flights from Cleveland to Florence from $427

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Florence departing on 7/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Cleveland to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:34 am - 11:37 pm
CLE
-
FLO
13h 03m
2 stops
American Airlines Logo
2:35 pm - 11:59 pm
FLO
-
CLE
9h 24m
2 stops
$427American Airlines
Tue, Jul 28 - Tue, Aug 4
American Airlines Logo
7:31 pm - 11:37 pm
CLE
-
FLO
4h 06m
1 stop
American Airlines Logo
2:35 pm - 6:39 pm
FLO
-
CLE
4h 04m
1 stop
$481American Airlines
Tue, Jul 28 - Tue, Aug 4
American Airlines Logo
7:31 pm - 11:37 pm
CLE
-
FLO
4h 06m
1 stop
American Airlines Logo
5:17 am - 4:34 pm
FLO
-
CLE
11h 17m
2 stops
$488American Airlines
Tue, Jul 28 - Mon, Aug 3
American Airlines Logo
10:34 am - 11:37 pm
CLE
-
FLO
13h 03m
2 stops
American Airlines Logo
5:17 am - 4:34 pm
FLO
-
CLE
11h 17m
2 stops
$495American Airlines
Mon, Jul 13 - Sun, Jul 19
American Airlines Logo
9:45 am - 10:58 pm
CLE
-
FLO
13h 13m
2 stops
American Airlines Logo
2:36 pm - 6:52 pm
FLO
-
CLE
4h 16m
1 stop
$514American Airlines
Sat, Oct 3 - Sun, Oct 4
American Airlines Logo
8:06 am - 2:10 pm
CLE
-
FLO
6h 04m
1 stop
American Airlines Logo
5:17 am - 11:12 am
FLO
-
CLE
5h 55m
1 stop
$518American Airlines
Tue, Jul 28 - Mon, Aug 3
American Airlines Logo
10:34 am - 11:37 pm
CLE
-
FLO
13h 03m
2 stops
American Airlines Logo
5:17 am - 11:12 am
FLO
-
CLE
5h 55m
1 stop
$525American Airlines
Mon, Jul 13 - Sun, Jul 19
American Airlines Logo
1:25 pm - 10:58 pm
CLE
-
FLO
9h 33m
2 stops
American Airlines Logo
5:09 am - 3:30 pm
FLO
-
CLE
10h 21m
2 stops
$530American Airlines
Sat, Oct 3 - Sun, Oct 4
American Airlines Logo
10:34 am - 11:37 pm
CLE
-
FLO
13h 03m
2 stops
American Airlines Logo
5:17 am - 4:34 pm
FLO
-
CLE
11h 17m
2 stops
$621American Airlines
Tue, Jul 28 - Sun, Aug 2
American Airlines Logo
7:31 pm - 11:37 pm
CLE
-
FLO
4h 06m
1 stop
American Airlines Logo
2:35 pm - 6:39 pm
FLO
-
CLE
4h 04m
1 stop
$639American Airlines
Mon, Jul 13 - Sun, Jul 19

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American Airlines flights from Cleveland to Florence, South Carolina

Our best American Airlines deals on Cleveland to Florence, South Carolina flight tickets
American Airlines
Jul 28
CLE10:34 amCleveland Hopkins Intl
13h 03m
2 stops
FLO11:37 pmFlorence
Aug 4
FLO2:35 pmFlorence
9h 24m
2 stops
CLE11:59 pmCleveland Hopkins Intl
$427
American Airlines
Jul 28
CLE7:31 pmCleveland Hopkins Intl
4h 06m
1 stop
FLO11:37 pmFlorence
Aug 4
FLO2:35 pmFlorence
4h 04m
1 stop
CLE6:39 pmCleveland Hopkins Intl
$481
American Airlines
Jul 28
CLE7:31 pmCleveland Hopkins Intl
4h 06m
1 stop
FLO11:37 pmFlorence
Aug 3
FLO5:17 amFlorence
11h 17m
2 stops
CLE4:34 pmCleveland Hopkins Intl
$488

momondo Fare Finder

 
Customize your flight search to find flights from Cleveland to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 17, 2026.
Use the filters below to find and compare flights from Cleveland to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 7/28

10:34 am-11:37 pm

2 stops13h 03m

Florence

Tue 8/4

2:35 pm-11:59 pm

2 stops9h 24m

$427
Quickest round-trip

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 7/28

7:31 pm-11:37 pm

1 stop4h 06m

Florence

Tue 8/4

2:35 pm-6:39 pm

1 stop4h 04m

$481

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 7/28

7:31 pm-11:37 pm

1 stop4h 06m

Florence

Mon 8/3

5:17 am-4:34 pm

2 stops11h 17m

$488

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Mon 7/13

10:34 am-11:37 pm

2 stops13h 03m

Florence

Sun 7/19

5:17 am-4:34 pm

2 stops11h 17m

$495

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Sat 10/3

9:45 am-10:58 pm

2 stops13h 13m

Florence

Sun 10/4

2:36 pm-6:52 pm

1 stop4h 16m

$514

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 7/28

8:06 am-2:10 pm

1 stop6h 04m

Florence

Mon 8/3

5:17 am-11:12 am

1 stop5h 55m

$518

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Mon 7/13

10:34 am-11:37 pm

2 stops13h 03m

Florence

Sun 7/19

5:17 am-11:12 am

1 stop5h 55m

$525

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Sat 10/3

1:25 pm-10:58 pm

2 stops9h 33m

Florence

Sun 10/4

5:09 am-3:30 pm

2 stops10h 21m

$530

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 7/28

10:34 am-11:37 pm

2 stops13h 03m

Florence

Sun 8/2

5:17 am-4:34 pm

2 stops11h 17m

$621

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Mon 7/13

7:31 pm-11:37 pm

1 stop4h 06m

Florence

Sun 7/19

2:35 pm-6:39 pm

1 stop4h 04m

$639

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Cleveland to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

Breeze Airways, American Airlines and Allegiant Air are the top three most popular airlines that fly to Florence, South Carolina from Cleveland according to our data. Breeze Airways is the first choice among our users, with 38% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Cleveland to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Cleveland to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cleveland to Florence, South Carolina (CLE to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Florence, South Carolina

Fastest flight time

13h 03m

Direct flights

None
The fastest flight from Cleveland to Florence, South Carolina takes 13h 03m
There are no direct flights from Cleveland to Florence, South Carolina. There are no popular flight routes from Cleveland to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Cleveland to Florence, South Carolina

  • How far is Cleveland Hopkins Intl to Florence by plane?

    There are 515.1 mi between Cleveland Hopkins Intl and Florence. In terms of flight time, this usually takes a little over 13h 03m.

  • When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Florence Airport?

    Prices for flights from Cleveland Hopkins Intl Airport to Florence Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Cleveland Hopkins Intl Airport to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Cleveland Hopkins Intl Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Cleveland.

Can I find flights from Cleveland to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Cleveland with this policy.

How can momondo help me find flights from Cleveland to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Cleveland to Florence.

I’m not ready to book a flight from Cleveland to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Cleveland to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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