Cheap flights from Chicago to Charleston from $107

The cheapest month to fly to Charleston from Chicago is in February. Flight prices, which tend to average around $101, are often lower during this time because this is during the off-season. The month of January is another great option to travel to Charleston, with average flight prices from Chicago averaging around $104.

The cheapest day to depart from Chicago to Charleston is on a Tuesday. Travelers who choose to depart for Charleston on a Tuesday will often find tickets for as low as $342. The most expensive day to fly to Charleston is Sunday, with ticket prices averaging around $400.

The cheapest time of day to fly to Charleston is at noon when flights can be purchased for as low as $373. In the morning is when there is more demand to fly to Charleston, so prices are often more expensive at around $385 per ticket.

Fly from Chicago O'Hare Intl to Charleston for the best Chicago - Charleston flight prices

You are more likely to see cheaper flights to Charleston from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Charleston for around $380 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Charleston from Chicago for as low as $329 on momondo.

There are 4 cabin classes available to choose from on Chicago to Charleston flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Southwest, Delta, and United Airlines are the most popular carriers operating from Chicago to Charleston

United Airlines, American Airlines and Southwest are the top three most popular airlines that fly to Charleston from Chicago according to our data. United Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Charleston. Keep in mind that there are 4 different airlines that fly to Charleston on a routine basis, so you have a few additional options to choose from.

Atlanta (ATL) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Atlanta (ATL) offer the lowest average round-trip price of $284.

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 4h 30m.

Charlotte (CLT) has the shortest average layover time for this route: 0h 57m.

As of July 2026, 15 flights take off from Chicago and land in Charleston each day. The most common flight departure time for this route is 6:00PM, with 45% of daily flights taking off at noon.

As of July 2026, there are 107 flights per week flying from Chicago to Charleston. The most common day of the week flights depart is Thu, with 20% of flights taking off on this day.