Cheap flights from Charlotte to St. Louis from $80

In general, December is the cheapest month to fly from Charlotte to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $299. The month of October is another great option to travel to St. Louis, with average flight prices from Charlotte averaging around $305.

The cheapest day to depart on your flight to St. Louis is on a Saturday when prices can be found for as low as $307. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $513. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

Flying to St. Louis from Charlotte in the morning is the least expensive time of day to depart. momondo users have found prices as low as $341 when looking at flights departing in the morning. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $383 per ticket.

Fly from Charlotte Douglas to Lambert-St Louis for the best Charlotte Douglas - Lambert-St Louis flight prices

You are more likely to see cheaper flights to St. Louis from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $341 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Charlotte for as low as $230 on momondo.

There are 3 cabin classes available to choose from on Charlotte to St. Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 1% on your flight if you consider stops on a Charlotte to St. Louis flight.

As of September 2026, prices for Charlotte to St. Louis flights are approximately 7% cheaper when compared to flights at the same time last year.

Southwest and Delta are the most popular carriers operating from Charlotte Douglas to Lambert-St Louis

American Airlines, Delta and Southwest are the top three most popular airlines that fly to St. Louis from Charlotte according to our data. American Airlines is the first choice among our users, with 67% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 3 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

As of September 2026, there are 2 flights per day flying from Charlotte to St. Louis. The most common time of day flights depart is 9:00PM, with 42% of flights taking off in the afternoon.

20 flights are operational weekly from Charlotte to St. Louis as of September 2026. The most popular departure day for this route is Mon, with 35% of flights per week taking off on this day.