Cheap flights from Charlotte to Buffalo from $104

If you aren’t able to travel during the month of April, then book flights to Buffalo from Charlotte during May instead. Flights to Buffalo in May, while not as cheap as those in April, still average around $357.

Our data shows that Tuesday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $385. Flights from Charlotte to Buffalo on a Sunday will generally be more expensive and average around $492. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

In the afternoon is the cheapest time of day to fly from Charlotte to Buffalo when you can find flight prices for as low as $396. Flying to Buffalo in the afternoon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Buffalo, so prices are often more expensive at around $422 per ticket.

Fly from Charlotte Douglas to Buffalo for the best Charlotte Douglas - Buffalo flight prices

You are more likely to see cheaper flights to Buffalo from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to Buffalo for around $402 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Buffalo from Charlotte for as low as $258 on momondo.

There are 2 cabin classes available to choose from on Charlotte to Buffalo flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 26% on your flight if you consider stops on a Charlotte to Buffalo flight.

As of November 2026, prices for Charlotte to Buffalo flights are approximately 700% more expensive when compared to flights at the same time last year.

Frontier is the most popular carrier operating from Charlotte Douglas to Buffalo

American Airlines, Avelo Airlines and Southwest are the top three most popular airlines that fly to Buffalo from Charlotte according to our data. American Airlines is the first choice among our users, with 75% of people opting to fly with this airline when traveling to Buffalo. Keep in mind that there are 6 different airlines that fly to Buffalo on a routine basis, so you have a few additional options to choose from.

Washington, D.C. (DCA) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Orlando (MCO) offer the lowest average round-trip price of $161.

Flights connecting via Washington, D.C. (DCA) have the shortest average one-way travel time: 7h 25m.

Washington, D.C. (DCA) has the shortest average layover time for this route: 4h 25m.

The number of flights available between Charlotte and Buffalo is 3 per day as of November 2026. The most frequent departure time is 9:00AM, with 42% of daily flights leaving in the afternoon.

As of November 2026, 21 flights take off from Charlotte and land in Buffalo each week. The most common flight departure day for this route is Thu, with 19% of weekly flights taking off on this day.