What airlines fly to Panama City, Florida?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Panama City, Florida from Buffalo according to our data. American Airlines is the first choice among our users, with 51% of people opting to fly with this airline when traveling to Panama City, Florida. Keep in mind that there are 3 different airlines that fly to Panama City, Florida on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Buffalo to Panama City NW Florida Beaches?

American Airlines and United Airlines are the most popular carriers operating from Buffalo to Panama City NW Florida Beaches

When did momondo last update prices for flights from Buffalo Airport to Panama City NW Florida Beaches Airport?

Prices for flights from Buffalo Airport to Panama City NW Florida Beaches Airport were last updated today.

How many operators does momondo search for flights from Buffalo Airport to Panama City NW Florida Beaches Airport?

The number of operators available for flights from Buffalo Airport to Panama City NW Florida Beaches Airport is 3 as of September 2026.

How old do you have to be to fly from Buffalo Airport to Panama City NW Florida Beaches Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Panama City NW Florida Beaches Airport.

What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$339 Cheap Flights from Buffalo to Panama City, Florida in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to Panama City

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:28 am - 12:42 pmBUF Buffalo-ECP Panama City NW Florida Beaches

8h 14m1 stop Washington, D.C. Reagan-National

4:32 pm - 11:52 pmECP Panama City NW Florida Beaches-BUF Buffalo

6h 20m1 stop Charlotte Douglas

$339American Airlines

Tue, Feb 2 - Tue, Feb 16

7:53 pm - 11:53 pmBUF Buffalo-ECP Panama City NW Florida Beaches

5h 00m1 stop Charlotte Douglas

8:05 am - 3:34 pmECP Panama City NW Florida Beaches-BUF Buffalo

6h 29m1 stop Charlotte Douglas

$339American Airlines

Sat, Oct 24 - Tue, Oct 27

9:30 am - 3:30 pmBUF Buffalo-ECP Panama City NW Florida Beaches

7h 00m1 stop Nashville Intl

7:55 am - 3:15 pmECP Panama City NW Florida Beaches-BUF Buffalo

6h 20m1 stop Nashville Intl

$339Southwest

Tue, Oct 27 - Tue, Nov 3

6:15 am - 3:30 pmBUF Buffalo-ECP Panama City NW Florida Beaches

10h 15m2 stops Baltimore/Washington Nashville Intl

7:55 am - 3:15 pmECP Panama City NW Florida Beaches-BUF Buffalo

6h 20m1 stop Nashville Intl

$344Southwest

Tue, Oct 27 - Tue, Nov 3

5:28 am - 12:41 pmBUF Buffalo-ECP Panama City NW Florida Beaches

8h 13m1 stop Washington, D.C. Reagan-National

12:02 pm - 6:10 pmECP Panama City NW Florida Beaches-BUF Buffalo

5h 08m1 stop Charlotte Douglas

$350American Airlines

Mon, Feb 1 - Mon, Feb 8

6:15 am - 3:30 pmBUF Buffalo-ECP Panama City NW Florida Beaches

10h 15m2 stops Baltimore/Washington Nashville Intl

7:55 am - 8:50 pmECP Panama City NW Florida Beaches-BUF Buffalo

11h 55m2 stops Nashville Intl Chicago Midway

$355Southwest

Tue, Oct 27 - Tue, Nov 3

6:30 am - 1:17 pmBUF Buffalo-ECP Panama City NW Florida Beaches

7h 47m1 stop Chicago O'Hare Intl

8:50 am - 9:17 pmECP Panama City NW Florida Beaches-BUF Buffalo

11h 27m2 stops Houston George Bush Intcntl Newark

$357United Airlines

Fri, Jan 8 - Sat, Jan 16

6:00 am - 9:07 amBUF Buffalo-ECP Panama City NW Florida Beaches

4h 07m1 stop Atlanta Hartsfield-Jackson

6:00 am - 11:06 amECP Panama City NW Florida Beaches-BUF Buffalo

4h 06m1 stop Atlanta Hartsfield-Jackson

$361Delta

Tue, Nov 3 - Tue, Nov 10

6:00 am - 4:17 pmBUF Buffalo-ECP Panama City NW Florida Beaches

11h 17m2 stops Newark Houston George Bush Intcntl

8:50 am - 11:01 pmECP Panama City NW Florida Beaches-BUF Buffalo

13h 11m2 stops Houston George Bush Intcntl Newark

$362United Airlines

Fri, Jan 8 - Sat, Jan 16

5:20 pm - 11:18 pmBUF Buffalo-ECP Panama City NW Florida Beaches

6h 58m1 stop Atlanta Hartsfield-Jackson

5:37 pm - 11:59 pmECP Panama City NW Florida Beaches-BUF Buffalo

5h 22m1 stop Atlanta Hartsfield-Jackson

$409Delta

Thu, Oct 29 - Sun, Nov 1

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Delta flights from Buffalo to Panama City, Florida

Our best Delta deals on Buffalo to Panama City, Florida flight tickets

Delta

Nov 3

BUF6:00 amBuffalo

4h 07m

1 stop

ECP9:07 amPanama City NW Florida Beaches

Nov 10

ECP6:00 amPanama City NW Florida Beaches

4h 06m

1 stop

BUF11:06 amBuffalo

$361

Delta

Oct 29

BUF5:20 pmBuffalo

6h 58m

1 stop

ECP11:18 pmPanama City NW Florida Beaches

Nov 1

ECP5:37 pmPanama City NW Florida Beaches

5h 22m

1 stop

BUF11:59 pmBuffalo

$409

Delta

Oct 30

BUF6:00 amBuffalo

6h 43m

1 stop

ECP11:43 amPanama City NW Florida Beaches

Nov 1

ECP5:37 pmPanama City NW Florida Beaches

5h 22m

1 stop

BUF11:59 pmBuffalo

$422

United Airlines flights from Buffalo to Panama City, Florida

Our best United Airlines deals on Buffalo to Panama City, Florida flight tickets

United Airlines

Oct 24

BUF10:46 amBuffalo

5h 28m

1 stop

ECP3:14 pmPanama City NW Florida Beaches

Oct 28

ECP9:06 amPanama City NW Florida Beaches

12h 53m

2 stops

BUF10:59 pmBuffalo

$444

United Airlines

Oct 24

BUF10:46 amBuffalo

12h 32m

2 stops

ECP10:18 pmPanama City NW Florida Beaches

Oct 28

ECP9:06 amPanama City NW Florida Beaches

12h 53m

2 stops

BUF10:59 pmBuffalo

$450

United Airlines

Oct 24

BUF10:46 amBuffalo

5h 28m

1 stop

ECP3:14 pmPanama City NW Florida Beaches

Oct 28

ECP11:30 amPanama City NW Florida Beaches

10h 29m

2 stops

BUF10:59 pmBuffalo

$484

momondo Fare Finder

Use the filters below to find and compare flights from Buffalo to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloPanama City

BUF Buffalo - ECP Panama City NW Florida Beaches

BUFECP

Buffalo

Tue 2/2

5:28 am-12:42 pm

1 stop8h 14m

Panama City NW Florida Beaches

Tue 2/16

4:32 pm-11:52 pm

1 stop6h 20m

$339

BuffaloPanama City

BUF Buffalo - ECP Panama City NW Florida Beaches

BUFECP

Buffalo

Sat 10/24

7:53 pm-11:53 pm

1 stop5h 00m

Panama City NW Florida Beaches

Tue 10/27

8:05 am-3:34 pm

1 stop6h 29m

$339

BuffaloPanama City

BUF Buffalo - ECP Panama City NW Florida Beaches

BUFECP

Buffalo

Tue 10/27

9:30 am-3:30 pm

1 stop7h 00m

Panama City NW Florida Beaches

Tue 11/3

7:55 am-3:15 pm

1 stop6h 20m

$339

BuffaloPanama City

BUF Buffalo - ECP Panama City NW Florida Beaches

BUFECP

Buffalo

Tue 10/27

6:15 am-3:30 pm

2 stops10h 15m

Panama City NW Florida Beaches

Tue 11/3

7:55 am-3:15 pm

1 stop6h 20m

$344

BuffaloPanama City

BUF Buffalo - ECP Panama City NW Florida Beaches

BUFECP

Buffalo

Mon 2/1

5:28 am-12:41 pm

1 stop8h 13m

Panama City NW Florida Beaches

Mon 2/8

12:02 pm-6:10 pm

1 stop5h 08m

$350

BuffaloPanama City

BUF Buffalo - ECP Panama City NW Florida Beaches

BUFECP

Buffalo

Tue 10/27

6:15 am-3:30 pm

2 stops10h 15m

Panama City NW Florida Beaches

Tue 11/3

7:55 am-8:50 pm

2 stops11h 55m

$355

BuffaloPanama City

BUF Buffalo - ECP Panama City NW Florida Beaches

BUFECP

Buffalo

Fri 1/8

6:30 am-1:17 pm

1 stop7h 47m

Panama City NW Florida Beaches

Sat 1/16

8:50 am-9:17 pm

2 stops11h 27m

$357

Quickest round-trip

BuffaloPanama City

BUF Buffalo - ECP Panama City NW Florida Beaches

BUFECP

Buffalo

Tue 11/3

6:00 am-9:07 am

1 stop4h 07m

Panama City NW Florida Beaches

Tue 11/10

6:00 am-11:06 am

1 stop4h 06m

$361

BuffaloPanama City

BUF Buffalo - ECP Panama City NW Florida Beaches

BUFECP

Buffalo

Fri 1/8

6:00 am-4:17 pm

2 stops11h 17m

Panama City NW Florida Beaches

Sat 1/16

8:50 am-11:01 pm

2 stops13h 11m

$362

BuffaloPanama City

BUF Buffalo - ECP Panama City NW Florida Beaches

BUFECP

Buffalo

Thu 10/29

5:20 pm-11:18 pm

1 stop6h 58m

Panama City NW Florida Beaches

Sun 11/1

5:37 pm-11:59 pm

1 stop5h 22m

$409

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first

How to get the cheapest flight ticket from Buffalo to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Buffalo and Panama City, Florida?

Prices are currently typical for flights on this route.

Typical prices usually range from $337 to $402.
The lowest price recently found on this route was $339.

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Buffalo is in August. Flight prices, which tend to average around $340, are often lower during this time because this is during the off-season. The month of October is another great option to travel to Panama City, Florida, with average flight prices from Buffalo averaging around $361.

Can stopping save me money on Buffalo to Panama City, Florida flights?

You could potentially save up to 60% on your flight if you consider stops on a Buffalo to Panama City, Florida flight.

When to book flights from Buffalo to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Buffalo to Panama City, Florida (BUF to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Panama City, Florida

Best Price Found	$404
Fastest flight time	4h 07m
Direct flights	None

The best one-way flight to Panama City, Florida from Buffalo in the past 72 hours is $404. The best round-trip flight deal from Buffalo to Panama City, Florida found on momondo in the last 72 hours is $339.

The fastest flight from Buffalo to Panama City, Florida takes 4h 07m

There are no direct flights from Buffalo to Panama City, Florida. There are no popular flight routes from Buffalo to Panama City, Florida.

Search flight deals

Frequently asked questions about flying from Buffalo to Panama City, Florida

How far is Buffalo to Panama City NW Florida Beaches by plane?
A flight from Buffalo to Panama City NW Florida Beaches will travel around 955.1 mi. By plane, this route typically takes 4h 07m.
When did momondo last update prices for flights from Buffalo Airport to Panama City NW Florida Beaches Airport?
Prices for flights from Buffalo Airport to Panama City NW Florida Beaches Airport were last updated today.
How many operators does momondo search for flights from Buffalo Airport to Panama City NW Florida Beaches Airport?
The number of operators available for flights from Buffalo Airport to Panama City NW Florida Beaches Airport is 3 as of September 2026.
How old do you have to be to fly from Buffalo Airport to Panama City NW Florida Beaches Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Panama City NW Florida Beaches Airport.
What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?
The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Buffalo to Panama City, Florida?
Based on momondo bookings for flights between Buffalo and Panama City, Florida, the leading airline is Delta, making up 55% of the total bookings. Other popular airlines include American Airlines with 34% and Southwest with 11%.

Best airlines flying from Buffalo to Panama City, Florida

Compare and see reviews for airlines that fly from Buffalo to Panama City, Florida with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $229	Free Cancellation	Rating 7.8 8,610 reviews	Search Delta flights
American Airlines	PriceFrom $328	Free Cancellation	Rating 7.0 12,099 reviews	Search American Airlines flights
Southwest	PriceFrom $361	Free Cancellation	Rating 8.0 4,201 reviews	Search Southwest flights

Panama City Beach

Rosemary Beach

Port St. Joe

Seaside

Mexico Beach

Seagrove Beach

Freeport

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Why should I use momondo to find a flight deal from Buffalo to Panama City?

It is quick and easy to find Buffalo to Panama City flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama City that suits you.

Can I find flights from Buffalo to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Buffalo which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Buffalo to Panama City?

Once all potential Buffalo to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Buffalo to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Buffalo are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from Buffalo to Panama City from $339

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Panama City departing on 2/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Delta flights from Buffalo to Panama City, Florida

Our best Delta deals on Buffalo to Panama City, Florida flight tickets

United Airlines flights from Buffalo to Panama City, Florida

Our best United Airlines deals on Buffalo to Panama City, Florida flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Buffalo to Panama City, Florida that are best for you.

See travel insights to Panama City from

How to get the cheapest flight ticket from Buffalo to Panama City, Florida

What is the typical price of a round-trip flight between Buffalo and Panama City, Florida?

What is the cheapest month to fly to Panama City, Florida?

Can stopping save me money on Buffalo to Panama City, Florida flights?

What is the cheapest airline that flies from Buffalo to Panama City NW Florida Beaches?

What airlines fly to Panama City, Florida?

When to book flights from Buffalo to Panama City, Florida

Cheap Buffalo to Panama City, Florida (BUF to ECP) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Buffalo to Panama City, Florida

Best airlines flying from Buffalo to Panama City, Florida

Compare and see reviews for airlines that fly from Buffalo to Panama City, Florida with momondo

Traveling to a place near Panama City?

Why use momondo?

An easier way to manage your Panama City, Florida trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Airlines are sorted and displayed according to clicks in the past 7 days on momondo

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List of cabin classes available on flights landing in Panama City. Availability may vary depending on flight origin and airline.

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