Cheap flights from St. Louis to Panama City from $114
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Panama City departing on 12/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Fly from
Fly to
Route
Depart
Return
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Wed 1/6
10:27 am-5:17 pm
1 stop6h 50m
Panama City NW Florida Beaches
Wed 1/13
7:09 am-2:55 pm
1 stop7h 46m
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Mon 11/9
10:37 am-5:09 pm
1 stop6h 32m
Panama City NW Florida Beaches
Sat 11/14
4:04 pm-11:33 pm
1 stop7h 29m
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Sat 1/9
6:00 am-11:04 am
1 stop5h 04m
Panama City NW Florida Beaches
Mon 2/1
7:05 pm-11:39 pm
1 stop4h 34m
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Mon 12/14
10:35 am-5:18 pm
1 stop6h 43m
Panama City NW Florida Beaches
Wed 12/16
12:13 pm-6:26 pm
1 stop6h 13m
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Mon 11/9
5:40 am-10:45 am
1 stop5h 05m
Panama City NW Florida Beaches
Sat 11/14
7:50 am-2:10 pm
2 stops6h 20m
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Wed 1/6
1:17 pm-9:40 pm
2 stops8h 23m
Panama City NW Florida Beaches
Wed 1/13
2:10 pm-9:37 pm
1 stop7h 27m
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Mon 12/14
3:00 pm-9:38 pm
1 stop6h 38m
Panama City NW Florida Beaches
Wed 12/16
1:30 pm-10:59 pm
2 stops9h 29m
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Sat 10/31
12:00 pm-3:22 pm
1 stop3h 22m
Panama City NW Florida Beaches
Sat 11/7
6:00 am-9:42 am
1 stop3h 42m
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Sat 10/31
10:47 am-3:22 pm
1 stop4h 35m
Panama City NW Florida Beaches
Thu 11/5
6:00 am-10:51 am
1 stop4h 51m
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Tue 11/3
4:15 pm-8:30 pm
1 stop4h 15m
Panama City NW Florida Beaches
Fri 11/6
5:55 pm-9:20 pm
1 stop3h 25m
See travel insights to Panama City from
How to get the cheapest flight ticket from St. Louis to Panama City, Florida
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the typical price of a round-trip flight between St. Louis and Panama City, Florida?
Prices are currently typical for flights on this route.
Typical prices usually range from $287 to $466.The lowest price recently found on this route was $305.
What is the cheapest month to fly to Panama City, Florida?
The cheapest month to fly to Panama City, Florida from St. Louis is in November. Flight prices, which tend to average around $236, are often lower during this time because this is during the off-season. The month of December is another great option to travel to Panama City, Florida, with average flight prices from St. Louis averaging around $302.
What is the cheapest day to depart on your flight to Panama City, Florida?
Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $364. On the other hand, Sunday is the most expensive day to depart from St. Louis because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $573.
What is the cheapest Lambert-St Louis to Panama City NW Florida Beaches flight route?
Fly from Lambert-St Louis to Panama City NW Florida Beaches for the best Lambert-St Louis - Panama City NW Florida Beaches flight prices
How far in advance should I book a flight from St. Louis to Panama City, Florida?
You are more likely to see cheaper flights to Panama City, Florida from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $368 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from St. Louis for as low as $332 on momondo.
What cabin class options are available on St. Louis to Panama City, Florida flights?
There is only 1 cabin class available to choose from on St. Louis to Panama City, Florida flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.
Can stopping save me money on St. Louis to Panama City, Florida flights?
You could potentially save up to 43% on your flight if you consider stops on a St. Louis to Panama City, Florida flight.
What is the cheapest airline that flies from Lambert-St Louis to Panama City NW Florida Beaches?
Delta, United Airlines, and Southwest are the most popular carriers operating from Lambert-St Louis to Panama City NW Florida Beaches
What airlines fly to Panama City, Florida?
Southwest, Allegiant Air and Delta are the top three most popular airlines that fly to Panama City, Florida from St. Louis according to our data. Southwest is the first choice among our users, with 37% of people opting to fly with this airline when traveling to Panama City, Florida. Keep in mind that there are 4 different airlines that fly to Panama City, Florida on a routine basis, so you have a few additional options to choose from.
When to book flights from St. Louis to Panama City, Florida
Cheap St. Louis to Panama City, Florida (STL to ECP) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from St. Louis to Panama City, Florida
Frequently asked questions about flying from St. Louis to Panama City, Florida
How far is Lambert-St Louis to Panama City NW Florida Beaches by plane?
The straight-line distance from Lambert-St Louis to Panama City NW Florida Beaches is 639.0 mi. 1h 45m is a normal flight duration for this route.
When did momondo last update prices for flights from Lambert-St Louis Airport to Panama City NW Florida Beaches Airport?
Prices for flights from Lambert-St Louis Airport to Panama City NW Florida Beaches Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Lambert-St Louis Airport to Panama City NW Florida Beaches Airport?
As of October 2026, there are 3 operators available to choose from for flights from Lambert-St Louis Airport to Panama City NW Florida Beaches Airport.
How old do you have to be to fly from Lambert-St Louis Airport to Panama City NW Florida Beaches Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Panama City NW Florida Beaches Airport.
What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?
The necessary travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from St. Louis to Panama City, Florida?
Based on momondo bookings for flights between St. Louis and Panama City, Florida, the leading plane model is Boeing 737 MAX 8, making up 52.38% of the total bookings. Other popular models include Boeing 737 with 14.29%, Boeing 737-700 Passenger/BBJ1 (winglets) with 9.52%, and Boeing 737-800 Passenger/BBJ2 (winglets) with 9.52%.
What is the most popular airline from St. Louis to Panama City, Florida?
Based on momondo bookings for flights between St. Louis and Panama City, Florida, the leading airline is Southwest, making up 57% of the total bookings. Other popular airlines include Delta with 31% and American Airlines with 13%.
Best airlines flying from St. Louis to Panama City, Florida
Compare and see reviews for airlines that fly from St. Louis to Panama City, Florida with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $196 | Free Cancellation | Rating 7.8 8,645 reviews | |||
| PriceFrom $226 | Free Cancellation | Rating 7.0 12,145 reviews | |||
| PriceFrom $266 | Free Cancellation | Rating 7.9 4,222 reviews |
Southwest Flights From St. Louis to Panama City, Florida
The lowest priced Southwest flight from St. Louis to Panama City, Florida from the last 72 hours was $266. Generally, Southwest has 5 flights on this route every week with an average price of $430. Southwest is rated 7.9/10 by our users.
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Why should I use momondo to find a flight deal from St. Louis to Panama City?
momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from St. Louis to Panama City. Millions of users trust and use momondo every year so you are in good hands.
Can I find flights from St. Louis to Panama City with flexible booking policies on momondo?
Flights from St. Louis to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.
How can momondo help me find flights from St. Louis to Panama City?
momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from St. Louis to Panama City.
I’m not ready to book a flight from St. Louis to Panama City right now. Can momondo alert me if prices change?
Yes. momondo can track prices for St. Louis to Panama City flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.