How long does it take to fly to St. Louis?

Flight times from South Carolina to St. Louis vary, but if you’re flying out of Charleston and flying into St. Louis (one of the most popular routes), then the duration is 2h 05m on average. Another popular route from South Carolina to St. Louis is flying from Columbia to St. Louis, which will take roughly 3h 34m. Keep in mind that layovers or delays could extend your travel time.

How many flights depart from South Carolina to St. Louis on average per day?

As of September 2025, there are 7 flights per day flying from South Carolina to St. Louis. The most common time of day flights depart is 11:00AM, with 77% of flights taking off at noon.

What airlines fly to St. Louis?

Delta, American Airlines and Southwest are the top three most popular airlines that fly to St. Louis from South Carolina according to our data. Delta is the first choice among our users, with 42% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 3 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

How many flights depart from South Carolina to St. Louis on average per week?

51 flights are operational weekly from South Carolina to St. Louis as of September 2025. The most popular departure day for this route is Thu, with 24% of flights per week taking off on this day.

What is the cheapest airline that flies from South Carolina to Lambert-St Louis?

Frontier, United Airlines, and Spirit Airlines are the most popular carriers operating from South Carolina to Lambert-St Louis

When did momondo last update prices for flights from South Carolina to Lambert-St Louis Airport?

Prices for flights from South Carolina to Lambert-St Louis Airport were last updated today.

How many operators does momondo search for flights from South Carolina to Lambert-St Louis Airport?

As of September 2025, there are 4 operators available to choose from for flights from South Carolina to Lambert-St Louis Airport.

How old do you have to be to fly from South Carolina to Lambert-St Louis Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Lambert-St Louis Airport.

What documentation or ID do you need to fly to Lambert-St Louis Airport?

The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$72 Cheap Flights from South Carolina to St. Louis in 2025/26

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Find the cheapest flights from South Carolina to St. Louis

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

7:00 am - 12:35 pmCHS-STL

6h 35m1 stop

6:00 am - 2:12 pmSTL-CHS

7h 12m1 stop

$197Delta

Find Deal

Wed, Oct 22 - Sun, Oct 26

2:35 pm - 7:30 pmCAE-STL

5h 55m1 stop

9:14 am - 2:05 pmSTL-CAE

3h 51m1 stop

$212American Airlines

Find Deal

Sat, Oct 18 - Sat, Oct 25

6:30 am - 10:49 amCLT-STL

5h 19m1 stop

6:30 am - 2:10 pmSTL-CLT

6h 40m2 stops

$222United Airlines

Find Deal

Wed, Oct 15 - Wed, Oct 22

9:15 pm - 12:15 amCLT-STL

4h 00m1 stop

5:05 pm - 7:50 pmSTL-CLT

1h 45mnonstop

$227Southwest

Find Deal

Sat, Dec 27 - Tue, Dec 30

2:01 pm - 9:06 amCLT-STL

20h 05m2 stops

9:32 pm - 1:50 pmSTL-CLT

15h 18m2 stops

$230Frontier

Find Deal

Fri, Oct 3 - Mon, Oct 6

11:52 am - 10:37 amSAV-STL

23h 45m2 stops

10:57 am - 10:12 amSTL-SAV

22h 15m1 stop

$230Multiple Airlines

Find Deal

Wed, Oct 22 - Sun, Oct 26

4:20 pm - 10:05 pmCLT-STL

6h 45m1 stop

2:05 pm - 11:20 pmSTL-CLT

8h 15m2 stops

$232Southwest

Find Deal

Wed, Oct 15 - Mon, Oct 27

10:19 am - 6:10 pmCLT-STL

8h 51m1 stop

7:52 pm - 9:55 amSTL-CLT

37h 03m2 stops

$233Multiple Airlines

Find Deal

Sat, Oct 11 - Tue, Oct 14

2:53 pm - 11:57 pmCAE-STL

10h 04m2 stops

5:00 am - 10:25 amSTL-CAE

4h 25m1 stop

$264United Airlines

Find Deal

Wed, Oct 1 - Sun, Oct 5

5:34 pm - 9:07 amCLT-STL

16h 33m1 stop

7:52 pm - 9:08 amSTL-CLT

36h 16m2 stops

$292Frontier

Find Deal

Fri, Oct 10 - Tue, Oct 14

Delta flights from South Carolina to St. Louis

Our best Delta deals on South Carolina to St. Louis flight tickets

Delta

Oct 22

CHS7:00 amCharleston

6h 35m

1 stop

STL12:35 pmLambert-St Louis

Oct 26

STL6:00 amLambert-St Louis

7h 12m

1 stop

CHS2:12 pmCharleston

$197

Find similar

Delta

Oct 11

CLT5:25 pmCharlotte Douglas

4h 08m

1 stop

STL8:33 pmLambert-St Louis

Oct 14

STL9:10 amLambert-St Louis

6h 30m

1 stop

CLT4:40 pmCharlotte Douglas

$217

Find similar

Delta

Nov 25

CLT6:00 amCharlotte Douglas

4h 46m

1 stop

STL9:46 amLambert-St Louis

Nov 27

STL6:40 amLambert-St Louis

7h 10m

1 stop

CLT2:50 pmCharlotte Douglas

$237

Find similar

American Airlines flights from South Carolina to St. Louis

Our best American Airlines deals on South Carolina to St. Louis flight tickets

American Airlines

Oct 18

CAE2:35 pmColumbia Metropolitan

5h 55m

1 stop

STL7:30 pmLambert-St Louis

Oct 25

STL9:14 amLambert-St Louis

3h 51m

1 stop

CAE2:05 pmColumbia Metropolitan

$212

Find similar

American Airlines

Oct 18

CAE5:59 pmColumbia Metropolitan

6h 55m

2 stops

STL11:54 pmLambert-St Louis

Oct 25

STL6:00 amLambert-St Louis

7h 05m

2 stops

CAE2:05 pmColumbia Metropolitan

$223

Find similar

American Airlines

Oct 11

CLT7:15 amCharlotte Douglas

2h 01m

STL8:16 amLambert-St Louis

Oct 14

STL6:00 amLambert-St Louis

5h 32m

1 stop

CLT12:32 pmCharlotte Douglas

$231

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Wed 10/22

7:00 am-12:35 pm

1 stop6h 35m

Lambert-St Louis

Sun 10/26

6:00 am-2:12 pm

1 stop7h 12m

$197

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Sat 10/18

2:35 pm-7:30 pm

1 stop5h 55m

Lambert-St Louis

Sat 10/25

9:14 am-2:05 pm

1 stop3h 51m

$212

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 10/15

6:30 am-10:49 am

1 stop5h 19m

Lambert-St Louis

Wed 10/22

6:30 am-2:10 pm

2 stops6h 40m

$222

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 12/27

9:15 pm-12:15 am

1 stop4h 00m

Lambert-St Louis

Tue 12/30

5:05 pm-7:50 pm

Nonstop1h 45m

$227

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Fri 10/3

2:01 pm-9:06 am

2 stops20h 05m

Lambert-St Louis

Mon 10/6

9:32 pm-1:50 pm

2 stops15h 18m

$230

SavannahSt. Louis

SAV - STL

SAVSTL

Savannah/Hilton Head

Wed 10/22

11:52 am-10:37 am

2 stops23h 45m

Lambert-St Louis

Sun 10/26

10:57 am-10:12 am

1 stop22h 15m

$230

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 10/15

4:20 pm-10:05 pm

1 stop6h 45m

Lambert-St Louis

Mon 10/27

2:05 pm-11:20 pm

2 stops8h 15m

$232

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 10/11

10:19 am-6:10 pm

1 stop8h 51m

Lambert-St Louis

Tue 10/14

7:52 pm-9:55 am

2 stops37h 03m

$233

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Wed 10/1

2:53 pm-11:57 pm

2 stops10h 04m

Lambert-St Louis

Sun 10/5

5:00 am-10:25 am

1 stop4h 25m

$264

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Fri 10/10

5:34 pm-9:07 am

1 stop16h 33m

Lambert-St Louis

Tue 10/14

7:52 pm-9:08 am

2 stops36h 16m

$292

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to St. Louis?

In general, September is the cheapest month to fly from South Carolina to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $337. The month of August is another great option to travel to St. Louis, with average flight prices from South Carolina averaging around $342.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Thursday when prices can be found for as low as $336. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $646. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from South Carolina in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $388 when looking at flights departing in the afternoon. In the evening is when there is more demand to fly to St. Louis, so prices are often more expensive at around $400 per ticket.

What is the cheapest South Carolina to Lambert-St Louis flight route?

Fly from Charleston to Lambert-St Louis for the best South Carolina - Lambert-St Louis flight prices

How far in advance should I book a flight to St. Louis?

You are more likely to see cheaper flights to St. Louis from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $397 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from South Carolina for as low as $331 on momondo.

What cabin class options are available on South Carolina to Lambert-St Louis flights?

There is only 1 cabin class available to choose from on South Carolina to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to St. Louis flights?

You could potentially save up to 33% on your flight if you consider stops on a South Carolina to St. Louis flight.

Cheap South Carolina to St. Louis flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to St. Louis

Best Price Found	$199
Fastest flight time	1h 56m
Direct flights	Every day
Airports in St. Louis	1 airport

The best one-way flight to St. Louis from South Carolina in the past 72 hours is $199. The best round-trip flight deal from South Carolina to St. Louis found on momondo in the last 72 hours is $277.

The fastest flight from South Carolina to St. Louis takes 1h 56m

Direct flights go from South Carolina to St. Louis every day.

There is 1 airport near St. Louis: Lambert-St Louis (STL)

Search flight deals

When did momondo last update prices for flights from South Carolina to Lambert-St Louis Airport?
Prices for flights from South Carolina to Lambert-St Louis Airport were last updated today.
How many operators does momondo search for flights from South Carolina to Lambert-St Louis Airport?
As of September 2025, there are 4 operators available to choose from for flights from South Carolina to Lambert-St Louis Airport.
How old do you have to be to fly from South Carolina to Lambert-St Louis Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Lambert-St Louis Airport.
What documentation or ID do you need to fly to Lambert-St Louis Airport?
The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from South Carolina to St. Louis?
momondo data reveals that the most frequently booked plane model on the route from South Carolina to St. Louis is Boeing 737-700 Passenger/BBJ1 (winglets), representing 43.75% of all bookings. The subsequent popular models are Boeing 737 MAX 8 at 10.42%, Boeing 737-900 Passenger/BBJ3 (winglets) at 8.33%, and Embraer 175 (Enhanced Winglets) at 4.17%.

Best airlines flying from South Carolina to St. Louis

Compare and see reviews for airlines that fly from South Carolina to St. Louis with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $168	Free Cancellation	Rating 7.9 7,964 reviews	Search Delta flights
American Airlines	PriceFrom $243	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Southwest	PriceFrom $286	Free Cancellation	Rating 8.0 4,242 reviews	Search Southwest flights

St. Charles

Chesterfield

Hermann

Fairview Heights

Florissant

Maryland Heights

O'Fallon

Fenton

Collinsville

Wentzville

Alton

St. Peters

Farmington

Festus

Glencoe

Clayton

Edwardsville

Eureka

Litchfield

Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to St. Louis?

Once all potential South Carolina to St. Louis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to St. Louis right now. Can momondo alert me if prices change?

Price alerts on flights to St. Louis from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your St. Louis trip

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Cheap flights from South Carolina to St. Louis from $72

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to St. Louis departing on 10/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Find the cheapest flights from South Carolina to St. Louis

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Delta flights from South Carolina to St. Louis

Our best Delta deals on South Carolina to St. Louis flight tickets

American Airlines flights from South Carolina to St. Louis

Our best American Airlines deals on South Carolina to St. Louis flight tickets

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Use the filters below to find and compare flights from South Carolina to St. Louis that are best for you.

See travel insights to St. Louis from

How to get the cheapest flight ticket from South Carolina to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

What is the cheapest day to depart on your flight to St. Louis?

What is the cheapest time of day to depart on your flight to St. Louis?

What is the cheapest South Carolina to Lambert-St Louis flight route?

Fly from Charleston to Lambert-St Louis for the best South Carolina - Lambert-St Louis flight prices

How far in advance should I book a flight to St. Louis?

What cabin class options are available on South Carolina to Lambert-St Louis flights?

There is only 1 cabin class available to choose from on South Carolina to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to St. Louis flights?

You could potentially save up to 33% on your flight if you consider stops on a South Carolina to St. Louis flight.

What is the cheapest airline that flies from South Carolina to Lambert-St Louis?

Frontier, United Airlines, and Spirit Airlines are the most popular carriers operating from South Carolina to Lambert-St Louis

What airlines fly to St. Louis?

How many flights depart from South Carolina to St. Louis on average per day?

As of September 2025, there are 7 flights per day flying from South Carolina to St. Louis. The most common time of day flights depart is 11:00AM, with 77% of flights taking off at noon.

How many flights depart from South Carolina to St. Louis on average per week?

51 flights are operational weekly from South Carolina to St. Louis as of September 2025. The most popular departure day for this route is Thu, with 24% of flights per week taking off on this day.

How long does it take to fly to St. Louis?

Cheap South Carolina to St. Louis flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to St. Louis

Best Price Found

Fastest flight time

Direct flights

Airports in St. Louis

When did momondo last update prices for flights from South Carolina to Lambert-St Louis Airport?

How many operators does momondo search for flights from South Carolina to Lambert-St Louis Airport?

How old do you have to be to fly from South Carolina to Lambert-St Louis Airport?

What documentation or ID do you need to fly to Lambert-St Louis Airport?

What is the most popular plane model from South Carolina to St. Louis?

Best airlines flying from South Carolina to St. Louis

Compare and see reviews for airlines that fly from South Carolina to St. Louis with momondo

Traveling to a place near St. Louis?

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to St. Louis?

Can I find flights from South Carolina to St. Louis with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to St. Louis?

I’m not ready to book a flight from South Carolina to St. Louis right now. Can momondo alert me if prices change?

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Missouri