How many flights depart from South Carolina to St. Louis on average per week?

47 flights are operational weekly from South Carolina to St. Louis as of November 2025. The most popular departure day for this route is Thu, with 21% of flights per week taking off on this day.

How long does it take to fly to St. Louis?

Flight times from South Carolina to St. Louis vary, but if you’re flying out of Greenville and flying into St. Louis (one of the most popular routes), then the duration is 3h 53m on average. Another popular route from South Carolina to St. Louis is flying from Myrtle Beach to St. Louis, which will take roughly 4h 11m. Keep in mind that layovers or delays could extend your travel time.

What is the cheapest airline that flies from South Carolina to Lambert-St Louis?

Frontier, Southwest, and Delta are the most popular carriers operating from South Carolina to Lambert-St Louis

How many flights depart from South Carolina to St. Louis on average per day?

As of November 2025, there are 6 flights per day flying from South Carolina to St. Louis. The most common time of day flights depart is 1:00PM, with 100% of flights taking off in the afternoon.

What airlines fly to St. Louis?

Delta, American Airlines and Southwest are the top three most popular airlines that fly to St. Louis from South Carolina according to our data. Delta is the first choice among our users, with 42% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 3 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from South Carolina to Lambert-St Louis Airport?

Prices for flights from South Carolina to Lambert-St Louis Airport were last updated today.

How many operators does momondo search for flights from South Carolina to Lambert-St Louis Airport?

As of November 2025, there are 4 operators available to choose from for flights from South Carolina to Lambert-St Louis Airport.

How old do you have to be to fly from South Carolina to Lambert-St Louis Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Lambert-St Louis Airport.

What documentation or ID do you need to fly to Lambert-St Louis Airport?

The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$47 Cheap Flights from South Carolina to St. Louis in 2025/26

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Cheap round-trip flights

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10:45 am - 10:33 pmCLT-STL

12h 48m1 stop

3:30 pm - 9:50 amSTL-CLT

17h 20m1 stop

$119Frontier

Find Deal

Tue, Dec 9 - Tue, Dec 16

9:20 pm - 10:33 pmCLT-STL

26h 13m1 stop

3:30 pm - 9:38 pmSTL-CLT

5h 08m1 stop

$120Frontier

Find Deal

Mon, Dec 8 - Thu, Dec 11

12:55 pm - 2:05 pmCLT-STL

2h 10mnonstop

4:15 pm - 7:00 pmSTL-CLT

1h 45mnonstop

$181Southwest

Find Deal

Thu, Dec 11 - Sun, Dec 14

5:50 pm - 9:00 pmCLT-STL

4h 10m1 stop

2:30 pm - 5:15 pmSTL-CLT

1h 45mnonstop

$191Southwest

Find Deal

Wed, Jan 21 - Mon, Jan 26

10:33 pm - 10:33 pmCLT-STL

25h 00m1 stop

2:47 pm - 11:59 pmSTL-CLT

8h 12m1 stop

$194Multiple Airlines

Find Deal

Thu, Dec 4 - Sun, Dec 7

5:30 am - 10:45 amCLT-STL

6h 15m1 stop

11:51 am - 5:34 pmSTL-CLT

4h 43m1 stop

$201Delta

Find Deal

Wed, Apr 29 - Wed, May 13

2:59 pm - 10:33 pmCHS-STL

8h 34m1 stop

12:04 pm - 8:54 pmSTL-CHS

31h 50m2 stops

$203Multiple Airlines

Find Deal

Thu, Dec 4 - Thu, Dec 11

7:00 am - 12:25 pmCAE-STL

6h 25m1 stop

10:13 am - 4:22 pmSTL-CAE

5h 09m1 stop

$211Delta

Find Deal

Wed, Feb 18 - Sat, Feb 21

5:33 pm - 6:43 pmCLT-STL

2h 10mnonstop

5:54 pm - 8:49 pmSTL-CLT

1h 55mnonstop

$217American Airlines

Find Deal

Wed, Dec 10 - Wed, Dec 17

6:26 pm - 7:30 pmCLT-STL

2h 04mnonstop

6:35 pm - 9:30 pmSTL-CLT

1h 55mnonstop

$240American Airlines

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Mon, Dec 29 - Sat, Jan 3

Frontier flights from South Carolina to St. Louis

Our best Frontier deals on South Carolina to St. Louis flight tickets

Frontier

Dec 9

CLT10:45 amCharlotte Douglas

12h 48m

1 stop

STL10:33 pmLambert-St Louis

Dec 16

STL3:30 pmLambert-St Louis

17h 20m

1 stop

CLT9:50 amCharlotte Douglas

$119

Find similar

Frontier

Dec 8

CLT9:20 pmCharlotte Douglas

26h 13m

1 stop

STL10:33 pmLambert-St Louis

Dec 11

STL3:30 pmLambert-St Louis

5h 08m

1 stop

CLT9:38 pmCharlotte Douglas

$120

Find similar

Frontier

Dec 3

CLT10:45 amCharlotte Douglas

12h 48m

1 stop

STL10:33 pmLambert-St Louis

Dec 10

STL3:30 pmLambert-St Louis

21h 11m

1 stop

CLT1:41 pmCharlotte Douglas

$121

Find similar

Delta flights from South Carolina to St. Louis

Our best Delta deals on South Carolina to St. Louis flight tickets

Delta

Apr 29

CLT5:30 amCharlotte Douglas

6h 15m

1 stop

STL10:45 amLambert-St Louis

May 13

STL11:51 amLambert-St Louis

4h 43m

1 stop

CLT5:34 pmCharlotte Douglas

$201

Find similar

Delta

Feb 18

CAE7:00 amColumbia Metropolitan

6h 25m

1 stop

STL12:25 pmLambert-St Louis

Feb 21

STL10:13 amLambert-St Louis

5h 09m

1 stop

CAE4:22 pmColumbia Metropolitan

$211

Find similar

Delta

Nov 24

CAE12:56 pmColumbia Metropolitan

6h 39m

1 stop

STL6:35 pmLambert-St Louis

Dec 1

STL7:02 pmLambert-St Louis

3h 29m

1 stop

CAE11:31 pmColumbia Metropolitan

$230

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Fly from

Fly to

Route

Depart

Return

Price

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 12/9

10:45 am-10:33 pm

1 stop12h 48m

Lambert-St Louis

Tue 12/16

3:30 pm-9:50 am

1 stop17h 20m

$119

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Mon 12/8

9:20 pm-10:33 pm

1 stop26h 13m

Lambert-St Louis

Thu 12/11

3:30 pm-9:38 pm

1 stop5h 08m

$120

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 12/11

12:55 pm-2:05 pm

Nonstop2h 10m

Lambert-St Louis

Sun 12/14

4:15 pm-7:00 pm

Nonstop1h 45m

$181

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 1/21

5:50 pm-9:00 pm

1 stop4h 10m

Lambert-St Louis

Mon 1/26

2:30 pm-5:15 pm

Nonstop1h 45m

$191

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 12/4

10:33 pm-10:33 pm

1 stop25h 00m

Lambert-St Louis

Sun 12/7

2:47 pm-11:59 pm

1 stop8h 12m

$194

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 4/29

5:30 am-10:45 am

1 stop6h 15m

Lambert-St Louis

Wed 5/13

11:51 am-5:34 pm

1 stop4h 43m

$201

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 12/4

2:59 pm-10:33 pm

1 stop8h 34m

Lambert-St Louis

Thu 12/11

12:04 pm-8:54 pm

2 stops31h 50m

$203

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Wed 2/18

7:00 am-12:25 pm

1 stop6h 25m

Lambert-St Louis

Sat 2/21

10:13 am-4:22 pm

1 stop5h 09m

$211

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 12/10

5:33 pm-6:43 pm

Nonstop2h 10m

Lambert-St Louis

Wed 12/17

5:54 pm-8:49 pm

Nonstop1h 55m

$217

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Mon 12/29

6:26 pm-7:30 pm

Nonstop2h 04m

Lambert-St Louis

Sat 1/3

6:35 pm-9:30 pm

Nonstop1h 55m

$240

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How to get the cheapest flight ticket from South Carolina to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to St. Louis?

In general, September is the cheapest month to fly from South Carolina to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $308. The month of August is another great option to travel to St. Louis, with average flight prices from South Carolina averaging around $342.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Thursday when prices can be found for as low as $336. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $646. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from South Carolina in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $388 when looking at flights departing in the afternoon. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $606 per ticket.

What is the cheapest South Carolina to Lambert-St Louis flight route?

Fly from Charleston to Lambert-St Louis for the best South Carolina - Lambert-St Louis flight prices

How far in advance should I book a flight to St. Louis?

You are more likely to see cheaper flights to St. Louis from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $398 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from South Carolina for as low as $331 on momondo.

What cabin class options are available on South Carolina to Lambert-St Louis flights?

There is only 1 cabin class available to choose from on South Carolina to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to St. Louis flights?

You could potentially save up to 17% on your flight if you consider stops on a South Carolina to St. Louis flight.

Cheap South Carolina to St. Louis flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to St. Louis

Fastest flight time	1h 56m
Direct flights	Every day
Airports in St. Louis	1 airport

The fastest flight from South Carolina to St. Louis takes 1h 56m

Direct flights go from South Carolina to St. Louis every day.

There is 1 airport near St. Louis: Lambert-St Louis (STL)

Search flight deals

When did momondo last update prices for flights from South Carolina to Lambert-St Louis Airport?
Prices for flights from South Carolina to Lambert-St Louis Airport were last updated today.
How many operators does momondo search for flights from South Carolina to Lambert-St Louis Airport?
As of November 2025, there are 4 operators available to choose from for flights from South Carolina to Lambert-St Louis Airport.
How old do you have to be to fly from South Carolina to Lambert-St Louis Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Lambert-St Louis Airport.
What documentation or ID do you need to fly to Lambert-St Louis Airport?
The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from South Carolina to St. Louis?
momondo data reveals that the most frequently booked plane model on the route from South Carolina to St. Louis is Boeing 737-700 Passenger/BBJ1 (winglets), representing 21.88% of all bookings. The subsequent popular models are Boeing 737-900 Passenger/BBJ3 (winglets) at 12.50%, Boeing 737 MAX 8 at 9.38%, and Embraer 175 (Enhanced Winglets) at 6.25%.

Best airlines flying from South Carolina to St. Louis

Compare and see reviews for airlines that fly from South Carolina to St. Louis with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $168	Free Cancellation	Rating 7.9 8,001 reviews	Search Delta flights
American Airlines	PriceFrom $243	Free Cancellation	Rating 7.2 11,040 reviews	Search American Airlines flights
Southwest	PriceFrom $287	Free Cancellation	Rating 8.0 4,241 reviews	Search Southwest flights

St. Charles

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Hermann

Fairview Heights

Florissant

Maryland Heights

O'Fallon

Wentzville

Fenton

Collinsville

St. Peters

Alton

Farmington

Festus

Glencoe

Edwardsville

Clayton

Eureka

Litchfield

Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to St. Louis?

Once all potential South Carolina to St. Louis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to St. Louis right now. Can momondo alert me if prices change?

Price alerts on flights to St. Louis from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from South Carolina to St. Louis from $47

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to St. Louis departing on 12/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from South Carolina to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

What is the cheapest day to depart on your flight to St. Louis?

What is the cheapest time of day to depart on your flight to St. Louis?

What is the cheapest South Carolina to Lambert-St Louis flight route?

Fly from Charleston to Lambert-St Louis for the best South Carolina - Lambert-St Louis flight prices

How far in advance should I book a flight to St. Louis?

What cabin class options are available on South Carolina to Lambert-St Louis flights?

There is only 1 cabin class available to choose from on South Carolina to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to St. Louis flights?

You could potentially save up to 17% on your flight if you consider stops on a South Carolina to St. Louis flight.

What is the cheapest airline that flies from South Carolina to Lambert-St Louis?

Frontier, Southwest, and Delta are the most popular carriers operating from South Carolina to Lambert-St Louis

What airlines fly to St. Louis?

How many flights depart from South Carolina to St. Louis on average per day?

As of November 2025, there are 6 flights per day flying from South Carolina to St. Louis. The most common time of day flights depart is 1:00PM, with 100% of flights taking off in the afternoon.

How many flights depart from South Carolina to St. Louis on average per week?

47 flights are operational weekly from South Carolina to St. Louis as of November 2025. The most popular departure day for this route is Thu, with 21% of flights per week taking off on this day.

How long does it take to fly to St. Louis?

Cheap South Carolina to St. Louis flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to St. Louis

Fastest flight time

Direct flights

Airports in St. Louis

When did momondo last update prices for flights from South Carolina to Lambert-St Louis Airport?

How many operators does momondo search for flights from South Carolina to Lambert-St Louis Airport?

How old do you have to be to fly from South Carolina to Lambert-St Louis Airport?

What documentation or ID do you need to fly to Lambert-St Louis Airport?

What is the most popular plane model from South Carolina to St. Louis?

Best airlines flying from South Carolina to St. Louis

Compare and see reviews for airlines that fly from South Carolina to St. Louis with momondo

Traveling to a place near St. Louis?

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to St. Louis?

Can I find flights from South Carolina to St. Louis with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to St. Louis?

I’m not ready to book a flight from South Carolina to St. Louis right now. Can momondo alert me if prices change?

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Missouri