Cheap flights from South Carolina to Portland from $68

The cheapest month to fly to Portland, Maine from South Carolina is in April. Flight prices, which tend to average around $261, are often lower during this time because this is during the off-season. If you aren’t able to travel to Portland, Maine during the month of April, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $269.

On average, the least expensive day to fly to Portland, Maine from South Carolina is on a Tuesday. momondo users have found tickets for Tuesday departures for as low as $152. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Monday is the most expensive day to depart from South Carolina because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $298.

At noon is the cheapest time of day to fly from South Carolina to Portland, Maine when you can find flight prices for as low as $183. Flying to Portland, Maine at noon is an ideal time because this is during off-peak travel hours. Try not to purchase tickets in the afternoon because they tend to be around $216. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Charleston to Portland for the best South Carolina - Portland flight prices

You are more likely to see cheaper flights to Portland, Maine from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Portland, Maine for around $287 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Portland, Maine from South Carolina for as low as $213 on momondo.

There are 2 cabin classes available to choose from on South Carolina to Portland, Maine flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Breeze Airways, Delta, and United Airlines are the most popular carriers operating from South Carolina to Portland

American Airlines, JetBlue and Delta are the top three most popular airlines that fly to Portland, Maine from South Carolina according to our data. American Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Portland, Maine. Keep in mind that there are 6 different airlines that fly to Portland, Maine on a routine basis, so you have a few additional options to choose from.

As of September 2026, 5 flights take off from South Carolina and land in Portland, Maine each week. The most common flight departure day for this route is Mon, with 40% of weekly flights taking off on this day.

The flight from South Carolina to Portland, Maine depends on which airports you’re departing and arriving from and whether or not you have a layover. If you fly from Myrtle Beach (a popular airport in South Carolina) to Boston (the most popular airport in Portland, Maine), then the flight time is 2h 14m on average. If you fly from Charleston (another popular airport in South Carolina) to Boston, then the average flight time is 2h 14m.