Cheap flights from South Carolina to Louisville from $46

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Louisville departing on 9/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Breeze Airways Logo
7:05 am - 8:58 amCHS-SDF
1h 53mnonstop
Breeze Airways Logo
8:52 pm - 10:28 pmSDF-CHS
1h 36mnonstop
$97Breeze Airways
Find Deal
Fri, Sep 26 - Mon, Sep 29
Breeze Airways Logo
7:05 am - 8:52 amCHS-SDF
1h 47mnonstop
Breeze Airways Logo
8:35 pm - 10:11 pmSDF-CHS
1h 36mnonstop
$103Breeze Airways
Find Deal
Fri, Aug 22 - Mon, Aug 25
 Logo
10:10 am - 10:04 pmCHS-SDF
11h 54m1 stop
 Logo
8:52 pm - 10:28 pmSDF-CHS
1h 36mnonstop
Fri, Sep 26 - Mon, Sep 29
Southwest Logo
7:00 am - 1:15 pmCHS-SDF
6h 15m1 stop
Southwest Logo
1:05 pm - 8:35 pmSDF-CHS
7h 30m1 stop
$171Southwest
Find Deal
Tue, Nov 11 - Tue, Nov 18
Southwest Logo
6:00 am - 2:45 pmCHS-SDF
8h 45m2 stops
Southwest Logo
1:05 pm - 8:35 pmSDF-CHS
7h 30m1 stop
$176Southwest
Find Deal
Tue, Nov 11 - Tue, Nov 18
Spirit Airlines Logo
8:30 pm - 11:45 pmMYR-SDF
27h 15m1 stop
Spirit Airlines Logo
6:00 am - 12:24 pmSDF-MYR
6h 24m1 stop
$181Spirit Airlines
Find Deal
Thu, Nov 13 - Sat, Nov 15
United Airlines Logo
5:34 pm - 10:24 pmGSP-SDF
4h 50m1 stop
United Airlines Logo
9:55 am - 2:16 pmSDF-GSP
4h 21m1 stop
$192United Airlines
Find Deal
Mon, Sep 22 - Tue, Sep 23
Spirit Airlines Logo
7:26 pm - 6:53 pmMYR-SDF
23h 27m1 stop
Spirit Airlines Logo
2:46 pm - 7:53 pmSDF-MYR
5h 07m1 stop
$200Spirit Airlines
Find Deal
Thu, Aug 28 - Sun, Aug 31
 Logo
12:08 pm - 10:04 pmCHS-SDF
9h 56m1 stop
 Logo
8:52 pm - 10:28 pmSDF-CHS
1h 36mnonstop
Thu, Sep 18 - Mon, Sep 22
United Airlines Logo
12:34 pm - 5:16 pmGSP-SDF
4h 42m1 stop
United Airlines Logo
10:55 am - 10:00 pmSDF-GSP
11h 05m2 stops
$262United Airlines
Find Deal
Mon, Aug 25 - Wed, Sep 3

Delta flights from South Carolina to Louisville

Our best Delta deals on South Carolina to Louisville flight tickets
Delta
Oct 21
MYR6:00 amMyrtle Beach Intl
3h 56m
1 stop
SDF9:56 amLouisville Intl
Oct 23
SDF8:15 pmLouisville Intl
3h 44m
1 stop
MYR11:59 pmMyrtle Beach Intl
Delta
Nov 7
CHS6:55 pmCharleston
5h 04m
1 stop
SDF11:59 pmLouisville Intl
Nov 15
SDF6:00 amLouisville Intl
5h 24m
1 stop
CHS11:24 amCharleston
Delta
Oct 4
GSP5:30 amGreenville
3h 57m
1 stop
SDF9:27 amLouisville Intl
Oct 5
SDF7:33 pmLouisville Intl
4h 19m
1 stop
GSP11:52 pmGreenville

American Airlines flights from South Carolina to Louisville

Our best American Airlines deals on South Carolina to Louisville flight tickets
American Airlines
Nov 10
SAV7:22 pmSavannah/Hilton Head
4h 37m
1 stop
SDF11:59 pmLouisville Intl
Nov 15
SDF3:38 pmLouisville Intl
6h 01m
1 stop
SAV9:39 pmSavannah/Hilton Head
American Airlines
Aug 30
CLT4:24 pmCharlotte Douglas
21h 48m
1 stop
SDF2:12 pmLouisville Intl
Aug 31
SDF3:43 pmLouisville Intl
1h 42m
CLT5:25 pmCharlotte Douglas
American Airlines
Sep 11
GSP8:37 pmGreenville
3h 22m
1 stop
SDF11:59 pmLouisville Intl
Sep 13
SDF5:32 pmLouisville Intl
5h 26m
2 stops
GSP10:58 pmGreenville

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from South Carolina to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 9/26

7:05 am-8:58 am

Nonstop1h 53m

Louisville Intl

Mon 9/29

8:52 pm-10:28 pm

Nonstop1h 36m

$97

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 8/22

7:05 am-8:52 am

Nonstop1h 47m

Louisville Intl

Mon 8/25

8:35 pm-10:11 pm

Nonstop1h 36m

$103

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 9/26

10:10 am-10:04 pm

1 stop11h 54m

Louisville Intl

Mon 9/29

8:52 pm-10:28 pm

Nonstop1h 36m

$142

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Tue 11/11

7:00 am-1:15 pm

1 stop6h 15m

Louisville Intl

Tue 11/18

1:05 pm-8:35 pm

1 stop7h 30m

$171

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Tue 11/11

6:00 am-2:45 pm

2 stops8h 45m

Louisville Intl

Tue 11/18

1:05 pm-8:35 pm

1 stop7h 30m

$176

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Thu 11/13

8:30 pm-11:45 pm

1 stop27h 15m

Louisville Intl

Sat 11/15

6:00 am-12:24 pm

1 stop6h 24m

$181

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Mon 9/22

5:34 pm-10:24 pm

1 stop4h 50m

Louisville Intl

Tue 9/23

9:55 am-2:16 pm

1 stop4h 21m

$192

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Thu 8/28

7:26 pm-6:53 pm

1 stop23h 27m

Louisville Intl

Sun 8/31

2:46 pm-7:53 pm

1 stop5h 07m

$200

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Thu 9/18

12:08 pm-10:04 pm

1 stop9h 56m

Louisville Intl

Mon 9/22

8:52 pm-10:28 pm

Nonstop1h 36m

$201

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Mon 8/25

12:34 pm-5:16 pm

1 stop4h 42m

Louisville Intl

Wed 9/3

10:55 am-10:00 pm

2 stops11h 05m

$262

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Louisville from

How to get the cheapest flight ticket from South Carolina to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Louisville?

If you are unable to visit Louisville during the month of August, then departing from South Carolina during the month July is also very affordable. Most momondo users find prices during this month for around $203.

What is the cheapest day to depart on your flight to Louisville?

On average, the least expensive day to fly to Louisville from South Carolina is on a Thursday. momondo users have found tickets for Thursday departures for as low as $92. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from South Carolina to Louisville on a Friday will generally be more expensive and average around $222. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Louisville?

Our data shows that the cheapest South Carolina to Louisville flights are usually those with departure times in the morning. Our users have found flights to Louisville in the morning for as low as $207. In the afternoon is when there is more demand to fly to Louisville, so prices are often more expensive at around $338 per ticket.

What is the cheapest South Carolina to Louisville Intl flight route?

Fly from Charleston to Louisville Intl for the best South Carolina - Louisville Intl flight prices

How far in advance should I book a flight to Louisville?

You are more likely to see cheaper flights to Louisville from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Louisville for around $303 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Louisville from South Carolina for as low as $164 on momondo.

What cabin class options are available on South Carolina to Louisville Intl flights?

There are 1 cabin classes available to choose from on South Carolina to Louisville Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Louisville flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Louisville.

Cheap South Carolina to Louisville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Louisville

Best Price Found

$46

Fastest flight time

1h 25m

Direct flights

Every day

Airports in Louisville

1 airport
The best one-way flight to Louisville from South Carolina in the past 72 hours is $46. The best round-trip flight deal from South Carolina to Louisville found on momondo in the last 72 hours is $97.
The fastest flight from South Carolina to Louisville takes 1h 25m
Direct flights go from South Carolina to Louisville every day.
There is 1 airport near Louisville: Louisville Intl (SDF)
  • When did momondo last update prices for flights from South Carolina to Louisville Intl Airport?

    Prices for flights from South Carolina to Louisville Intl Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Louisville Intl Airport?

  • How old do you have to be to fly from South Carolina to Louisville Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The required travel and health documents for your Louisville Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Louisville Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from South Carolina to Louisville?

Best airlines flying from South Carolina to Louisville

Compare and see reviews for airlines that fly from South Carolina to Louisville with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $31Free CancellationRating
6.3
8,055 reviews
Search Spirit Airlines flights
Breeze AirwaysPriceFrom $91Free CancellationRating
8.0
191 reviews
Search Breeze Airways flights
DeltaPriceFrom $176Free CancellationRating
8.0
7,985 reviews
Search Delta flights
American AirlinesPriceFrom $198Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $233Free CancellationRating
7.4
8,917 reviews
Search United Airlines flights

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
West Baden Springs
Bardstown
Jeffersonville
Shepherdsville
New Albany
Elizabeth
Corydon
Charlestown
Springfield
Brandenburg
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Louisville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Louisville. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Louisville with flexible booking policies on momondo?

All flight searches from South Carolina to Louisville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Louisville?

Once you have performed a search for South Carolina to Louisville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Louisville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from South Carolina to Louisville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Louisville and let you know when they change.

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1 adult
Tue 8/12
Tue 8/19

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