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Cheap flights from South Carolina to Louisville from $59

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Louisville departing on 7/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
6:01 pm - 1:00 pm
CLT
-
SDF
18h 59m1 stop
Spirit Airlines Logo
3:36 pm - 12:40 am
SDF
-
CLT
9h 04m1 stop
$194Spirit Airlines
Do, Feb 5 - So, Feb 8
Delta Logo
2:59 pm - 8:42 pm
CHS
-
SDF
5h 43m1 stop
Delta Logo
9:35 am - 3:28 pm
SDF
-
CHS
5h 53m1 stop
$195Delta
Di, Apr 7 - Di, Apr 14
American Airlines Logo
6:25 am - 9:51 am
SAV
-
SDF
3h 26m1 stop
American Airlines Logo
6:50 pm - 10:54 pm
SDF
-
SAV
4h 04m1 stop
$195American Airlines
Di, Feb 17 - Di, Feb 17
Multiple Airlines Logo
7:43 pm - 2:38 pm
CLT
-
SDF
18h 55m1 stop
Multiple Airlines Logo
9:30 am - 8:26 am
SDF
-
CLT
22h 56m1 stop
$196Multiple Airlines
Mi, Feb 11 - Mo, Feb 16
Multiple Airlines Logo
11:35 am - 1:00 pm
CLT
-
SDF
25h 25m1 stop
Multiple Airlines Logo
3:36 pm - 11:59 pm
SDF
-
CLT
32h 23m2 stops
$198Multiple Airlines
Di, Feb 3 - Di, Feb 10
United Airlines Logo
2:58 pm - 7:43 pm
CHS
-
SDF
4h 45m1 stop
United Airlines Logo
8:29 am - 2:02 pm
SDF
-
CHS
5h 33m1 stop
$206United Airlines
Mi, Jan 28 - Mo, Feb 2
United Airlines Logo
2:58 pm - 10:30 pm
CHS
-
SDF
7h 32m2 stops
United Airlines Logo
2:05 pm - 8:02 pm
SDF
-
CHS
5h 57m1 stop
$211United Airlines
Mi, Jan 28 - Mo, Feb 2
American Airlines Logo
4:35 pm - 10:05 pm
CHS
-
SDF
5h 30m1 stop
American Airlines Logo
7:40 am - 2:25 pm
SDF
-
CHS
6h 45m1 stop
$217American Airlines
Fr, Jan 23 - Mi, Jan 28
Southwest Logo
5:50 pm - 10:40 pm
SAV
-
SDF
4h 50m1 stop
Southwest Logo
8:55 am - 6:25 pm
SDF
-
SAV
9h 30m2 stops
$287Southwest
Sa, Apr 4 - Mi, Apr 8
Southwest Logo
5:40 pm - 10:45 pm
SAV
-
SDF
5h 05m1 stop
Southwest Logo
5:25 am - 10:55 am
SDF
-
SAV
5h 30m1 stop
$298Southwest
Do, Jan 29 - So, Feb 1

Southwest flights from South Carolina to Louisville

Our best Southwest deals on South Carolina to Louisville flight tickets
Southwest
Mar 3
MYR8:15 amMyrtle Beach Intl
8h 35m
2 stops
SDF4:50 pmLouisville Intl
Mar 7
SDF5:30 amLouisville Intl
4h 30m
1 stop
MYR10:00 amMyrtle Beach Intl
$266
Southwest
Mar 3
MYR11:05 amMyrtle Beach Intl
11h 40m
2 stops
SDF10:45 pmLouisville Intl
Mar 7
SDF11:55 amLouisville Intl
7h 40m
2 stops
MYR7:35 pmMyrtle Beach Intl
$272
Southwest
Apr 4
SAV5:50 pmSavannah/Hilton Head
4h 50m
1 stop
SDF10:40 pmLouisville Intl
Apr 8
SDF8:55 amLouisville Intl
9h 30m
2 stops
SAV6:25 pmSavannah/Hilton Head
$287

American Airlines flights from South Carolina to Louisville

Our best American Airlines deals on South Carolina to Louisville flight tickets
American Airlines
Feb 17
SAV6:25 amSavannah/Hilton Head
3h 26m
1 stop
SDF9:51 amLouisville Intl
Feb 17
SDF6:50 pmLouisville Intl
4h 04m
1 stop
SAV10:54 pmSavannah/Hilton Head
$195
American Airlines
Jan 29
CLT10:18 pmCharlotte Douglas
14h 14m
1 stop
SDF12:32 pmLouisville Intl
Jan 30
SDF3:33 pmLouisville Intl
1h 44m
CLT5:17 pmCharlotte Douglas
$213
American Airlines
Jan 23
CHS4:35 pmCharleston
5h 30m
1 stop
SDF10:05 pmLouisville Intl
Jan 28
SDF7:40 amLouisville Intl
6h 45m
1 stop
CHS2:25 pmCharleston
$217

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated Januar 8, 2026.
Use the filters below to find and compare flights from South Carolina to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Do 2/5

6:01 pm-1:00 pm

1 stop18h 59m

Louisville Intl

So 2/8

3:36 pm-12:40 am

1 stop9h 04m

$194

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Di 4/7

2:59 pm-8:42 pm

1 stop5h 43m

Louisville Intl

Di 4/14

9:35 am-3:28 pm

1 stop5h 53m

$195

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Di 2/17

6:25 am-9:51 am

1 stop3h 26m

Louisville Intl

Di 2/17

6:50 pm-10:54 pm

1 stop4h 04m

$195

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Mi 2/11

7:43 pm-2:38 pm

1 stop18h 55m

Louisville Intl

Mo 2/16

9:30 am-8:26 am

1 stop22h 56m

$196

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Di 2/3

11:35 am-1:00 pm

1 stop25h 25m

Louisville Intl

Di 2/10

3:36 pm-11:59 pm

2 stops32h 23m

$198

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Mi 1/28

2:58 pm-7:43 pm

1 stop4h 45m

Louisville Intl

Mo 2/2

8:29 am-2:02 pm

1 stop5h 33m

$206

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Mi 1/28

2:58 pm-10:30 pm

2 stops7h 32m

Louisville Intl

Mo 2/2

2:05 pm-8:02 pm

1 stop5h 57m

$211

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fr 1/23

4:35 pm-10:05 pm

1 stop5h 30m

Louisville Intl

Mi 1/28

7:40 am-2:25 pm

1 stop6h 45m

$217

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Sa 4/4

5:50 pm-10:40 pm

1 stop4h 50m

Louisville Intl

Mi 4/8

8:55 am-6:25 pm

2 stops9h 30m

$287

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Do 1/29

5:40 pm-10:45 pm

1 stop5h 05m

Louisville Intl

So 2/1

5:25 am-10:55 am

1 stop5h 30m

$298

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Louisville from

How to get the cheapest flight ticket from South Carolina to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Louisville?

On average, the least expensive day to fly to Louisville from South Carolina is on a Thursday. momondo users have found tickets for Thursday departures for as low as $92. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from South Carolina to Louisville on a Friday will generally be more expensive and average around $258. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest South Carolina to Louisville Intl flight route?

Fly from Charleston to Louisville Intl for the best South Carolina - Louisville Intl flight prices

What cabin class options are available on South Carolina to Louisville Intl flights?

There are 2 cabin classes available to choose from on South Carolina to Louisville Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Louisville flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Louisville.

Cheap South Carolina to Louisville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Louisville

Best Price Found

$277

Fastest flight time

1h 30m

Direct flights

Every day

Airports in Louisville

1 airport
The best flight deal from South Carolina to Louisville found on momondo in the last 72 hours is $277
The fastest flight from South Carolina to Louisville takes 1h 30m
Direct flights go from South Carolina to Louisville every day.
There is 1 airport in Louisville. From South Carolina there are direct flights to Louisville Intl (SDF).
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Louisville Intl Airport?

    Prices for flights from South Carolina to Louisville Intl Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Louisville Intl Airport?

  • How old do you have to be to fly from South Carolina to Louisville Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The required travel and health documents for your Louisville Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Louisville Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from South Carolina to Louisville?

Best airlines flying from South Carolina to Louisville

Compare and see reviews for airlines that fly from South Carolina to Louisville with momondo
Airline
Rating
Free Cancellation
Price
Breeze AirwaysPriceFrom $51Free CancellationRating
8.2
255 reviews
Search Breeze Airways flights
DeltaPriceFrom $176Free CancellationRating
7.9
8,029 reviews
Search Delta flights
American AirlinesPriceFrom $196Free CancellationRating
7.2
11,095 reviews
Search American Airlines flights

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
West Baden Springs
Bardstown
Jeffersonville
Shepherdsville
New Albany
Corydon
Elizabeth
Charlestown
Brandenburg
Springfield
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Louisville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Louisville. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Louisville with flexible booking policies on momondo?

All flight searches from South Carolina to Louisville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Louisville?

Once you have performed a search for South Carolina to Louisville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Louisville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from South Carolina to Louisville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Louisville and let you know when they change.

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