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Cheap flights from South Carolina to Louisville from $39

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Louisville departing on 5/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
3:54 pm - 8:48 pm
CHS
-
SDF
4h 54m
1 stop
Breeze Airways Logo
8:28 pm - 10:06 pm
SDF
-
CHS
1h 38mnonstop
$152Breeze Airways
Fri, Jun 5 - Mon, Jun 8
Breeze Airways Logo
7:00 am - 8:46 am
CHS
-
SDF
1h 46mnonstop
Breeze Airways Logo
8:28 pm - 10:06 pm
SDF
-
CHS
1h 38mnonstop
$178Breeze Airways
Fri, Jun 5 - Mon, Jun 8
Multiple Airlines Logo
7:47 pm - 9:49 am
CHS
-
SDF
14h 02m
1 stop
Multiple Airlines Logo
8:28 pm - 10:06 pm
SDF
-
CHS
1h 38mnonstop
$183Multiple Airlines
Thu, Aug 20 - Mon, Aug 24
Multiple Airlines Logo
8:45 am - 10:24 am
SAV
-
SDF
1h 39mnonstop
Multiple Airlines Logo
12:20 pm - 1:55 pm
SDF
-
SAV
25h 35m
1 stop
$204Multiple Airlines
Sun, Jun 21 - Wed, Jun 24
Spirit Airlines Logo
3:55 pm - 11:14 am
CLT
-
SDF
19h 19m
1 stop
Spirit Airlines Logo
12:42 pm - 8:21 am
SDF
-
CLT
19h 39m
1 stop
$238Spirit Airlines
Tue, Mar 24 - Tue, Mar 31
American Airlines Logo
5:20 am - 8:38 am
GSP
-
SDF
3h 18m
1 stop
American Airlines Logo
6:00 am - 11:01 am
SDF
-
GSP
5h 01m
1 stop
$249American Airlines
Wed, Apr 22 - Sat, Apr 25
Delta Logo
5:34 am - 9:28 am
CAE
-
SDF
3h 54m
1 stop
Delta Logo
6:00 am - 9:18 am
SDF
-
CAE
3h 18m
1 stop
$249Delta
Thu, Mar 26 - Sun, Mar 29
Spirit Airlines Logo
7:17 pm - 11:41 am
CLT
-
SDF
16h 24m
1 stop
Spirit Airlines Logo
12:36 pm - 11:47 pm
SDF
-
CLT
11h 11m
1 stop
$250Spirit Airlines
Sun, Apr 19 - Fri, Apr 24
Delta Logo
5:33 am - 11:58 am
SAV
-
SDF
6h 25m
1 stop
Delta Logo
5:35 pm - 10:11 pm
SDF
-
SAV
4h 36m
1 stop
$257Delta
Tue, Apr 7 - Thu, Apr 9
American Airlines Logo
4:28 pm - 9:28 pm
GSP
-
SDF
5h 00m
1 stop
American Airlines Logo
6:00 am - 11:01 am
SDF
-
GSP
5h 01m
1 stop
$262American Airlines
Sat, Apr 18 - Mon, Apr 20

Breeze Airways flights from South Carolina to Louisville

Our best Breeze Airways deals on South Carolina to Louisville flight tickets
Breeze Airways
Jun 5
CHS3:54 pmCharleston
4h 54m
1 stop
SDF8:48 pmLouisville Intl
Jun 8
SDF8:28 pmLouisville Intl
1h 38m
CHS10:06 pmCharleston
$152
Breeze Airways
Jun 5
CHS3:54 pmCharleston
4h 54m
1 stop
SDF8:48 pmLouisville Intl
Jun 8
SDF8:28 pmLouisville Intl
1h 38m
CHS10:06 pmCharleston
$154
Breeze Airways
Jun 5
CHS7:00 amCharleston
1h 46m
SDF8:46 amLouisville Intl
Jun 8
SDF8:28 pmLouisville Intl
1h 38m
CHS10:06 pmCharleston
$178

Spirit Airlines flights from South Carolina to Louisville

Our best Spirit Airlines deals on South Carolina to Louisville flight tickets
Spirit Airlines
Mar 24
CLT3:55 pmCharlotte Douglas
19h 19m
1 stop
SDF11:14 amLouisville Intl
Mar 31
SDF12:42 pmLouisville Intl
19h 39m
1 stop
CLT8:21 amCharlotte Douglas
$238
Spirit Airlines
Apr 19
CLT7:17 pmCharlotte Douglas
16h 24m
1 stop
SDF11:41 amLouisville Intl
Apr 24
SDF12:36 pmLouisville Intl
11h 11m
1 stop
CLT11:47 pmCharlotte Douglas
$250
Spirit Airlines
Apr 30
CLT11:12 amCharlotte Douglas
5h 53m
1 stop
SDF5:05 pmLouisville Intl
May 4
SDF12:36 pmLouisville Intl
21h 38m
1 stop
CLT10:14 amCharlotte Douglas
$261

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 28, 2026.
Use the filters below to find and compare flights from South Carolina to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 6/5

3:54 pm-8:48 pm

1 stop4h 54m

Louisville Intl

Mon 6/8

8:28 pm-10:06 pm

Nonstop1h 38m

$152

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 6/5

7:00 am-8:46 am

Nonstop1h 46m

Louisville Intl

Mon 6/8

8:28 pm-10:06 pm

Nonstop1h 38m

$178

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Thu 8/20

7:47 pm-9:49 am

1 stop14h 02m

Louisville Intl

Mon 8/24

8:28 pm-10:06 pm

Nonstop1h 38m

$183

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Sun 6/21

8:45 am-10:24 am

Nonstop1h 39m

Louisville Intl

Wed 6/24

12:20 pm-1:55 pm

1 stop25h 35m

$204

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Tue 3/24

3:55 pm-11:14 am

1 stop19h 19m

Louisville Intl

Tue 3/31

12:42 pm-8:21 am

1 stop19h 39m

$238

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Wed 4/22

5:20 am-8:38 am

1 stop3h 18m

Louisville Intl

Sat 4/25

6:00 am-11:01 am

1 stop5h 01m

$249

ColumbiaLouisville

CAE - SDF

CAESDF

Columbia Metropolitan

Thu 3/26

5:34 am-9:28 am

1 stop3h 54m

Louisville Intl

Sun 3/29

6:00 am-9:18 am

1 stop3h 18m

$249

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Sun 4/19

7:17 pm-11:41 am

1 stop16h 24m

Louisville Intl

Fri 4/24

12:36 pm-11:47 pm

1 stop11h 11m

$250

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Tue 4/7

5:33 am-11:58 am

1 stop6h 25m

Louisville Intl

Thu 4/9

5:35 pm-10:11 pm

1 stop4h 36m

$257

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Sat 4/18

4:28 pm-9:28 pm

1 stop5h 00m

Louisville Intl

Mon 4/20

6:00 am-11:01 am

1 stop5h 01m

$262

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Louisville from

How to get the cheapest flight ticket from South Carolina to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Louisville?

If you are unable to visit Louisville during the month of July, then departing from South Carolina during the month August is also very affordable. Most momondo users find prices during this month for around $236.

What is the cheapest day to depart on your flight to Louisville?

On average, the least expensive day to fly to Louisville from South Carolina is on a Thursday. momondo users have found tickets for Thursday departures for as low as $92. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from South Carolina to Louisville on a Friday will generally be more expensive and average around $258. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest South Carolina to Louisville Intl flight route?

Fly from Charleston to Louisville Intl for the best South Carolina - Louisville Intl flight prices

What cabin class options are available on South Carolina to Louisville Intl flights?

There are 2 cabin classes available to choose from on South Carolina to Louisville Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Louisville flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Louisville.

Cheap South Carolina to Louisville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Louisville

Fastest flight time

1h 30m

Direct flights

Every day

Airports in Louisville

1 airport
The fastest flight from South Carolina to Louisville takes 1h 30m
Direct flights go from South Carolina to Louisville every day.
There is 1 airport in Louisville. From South Carolina there are direct flights to Louisville Intl (SDF).
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Louisville Intl Airport?

    Prices for flights from South Carolina to Louisville Intl Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Louisville Intl Airport?

  • How old do you have to be to fly from South Carolina to Louisville Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The required travel and health documents for your Louisville Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Louisville Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from South Carolina to Louisville?

Best airlines flying from South Carolina to Louisville

Compare and see reviews for airlines that fly from South Carolina to Louisville with momondo
Airline
Rating
Free Cancellation
Price
Breeze AirwaysPriceFrom $49Free CancellationRating
8.1
271 reviews
Search Breeze Airways flights
DeltaPriceFrom $125Free CancellationRating
7.9
8,245 reviews
Search Delta flights
American AirlinesPriceFrom $196Free CancellationRating
7.1
11,367 reviews
Search American Airlines flights

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
West Baden Springs
Bardstown
Jeffersonville
Shepherdsville
New Albany
Corydon
Elizabeth
Brandenburg
Charlestown
Springfield
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Louisville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Louisville. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Louisville with flexible booking policies on momondo?

All flight searches from South Carolina to Louisville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Louisville?

Once you have performed a search for South Carolina to Louisville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Louisville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from South Carolina to Louisville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Louisville and let you know when they change.

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