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Cheap flights from South Carolina to Louisville from $53

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Louisville departing on 8/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
6:16 pm - 7:55 pm
SAV
-
SDF
1h 39mnonstop
Allegiant Air Logo
8:45 pm - 10:19 pm
SDF
-
SAV
1h 34mnonstop
$82Allegiant Air
Thu, Aug 13 - Sun, Aug 16
Allegiant Air Logo
6:16 pm - 7:55 pm
SAV
-
SDF
1h 39mnonstop
Allegiant Air Logo
8:45 pm - 10:19 pm
SDF
-
SAV
1h 34mnonstop
$84Allegiant Air
Thu, Aug 13 - Sun, Aug 16
Breeze Airways Logo
6:10 am - 8:02 am
CHS
-
SDF
1h 52mnonstop
Breeze Airways Logo
7:59 pm - 9:34 pm
SDF
-
CHS
1h 35mnonstop
$122Breeze Airways
Fri, Oct 23 - Mon, Oct 26
Breeze Airways Logo
6:10 am - 8:02 am
CHS
-
SDF
1h 52mnonstop
Breeze Airways Logo
7:59 pm - 9:34 pm
SDF
-
CHS
1h 35mnonstop
$128Breeze Airways
Fri, Oct 23 - Mon, Oct 26
Multiple Airlines Logo
6:16 pm - 7:55 pm
SAV
-
SDF
1h 39mnonstop
Multiple Airlines Logo
6:55 pm - 12:22 pm
SDF
-
SAV
17h 27m
1 stop
$138Multiple Airlines
Thu, Aug 13 - Sun, Aug 16
Multiple Airlines Logo
6:16 pm - 7:55 pm
SAV
-
SDF
1h 39mnonstop
Multiple Airlines Logo
6:55 pm - 12:22 pm
SDF
-
SAV
17h 27m
1 stop
$148Multiple Airlines
Thu, Aug 13 - Sun, Aug 16
American Airlines Logo
3:27 pm - 9:31 pm
HHH
-
SDF
6h 04m
1 stop
American Airlines Logo
6:05 am - 11:09 am
SDF
-
HHH
5h 04m
1 stop
$261American Airlines
Wed, Aug 19 - Tue, Aug 25
Delta Logo
6:00 am - 10:19 am
CAE
-
SDF
4h 19m
1 stop
Delta Logo
11:04 am - 5:11 pm
SDF
-
CAE
6h 07m
1 stop
$271Delta
Sat, Sep 26 - Tue, Sep 29
American Airlines Logo
5:19 pm - 9:31 pm
GSP
-
SDF
4h 12m
1 stop
American Airlines Logo
2:36 pm - 8:46 pm
SDF
-
GSP
6h 10m
1 stop
$273American Airlines
Tue, Aug 11 - Tue, Aug 25
Delta Logo
1:59 pm - 7:30 pm
CAE
-
SDF
5h 31m
1 stop
Delta Logo
7:05 am - 1:14 pm
SDF
-
CAE
6h 09m
1 stop
$280Delta
Sat, Sep 26 - Fri, Oct 2

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Allegiant Air flights from South Carolina to Louisville

Our best Allegiant Air deals on South Carolina to Louisville flight tickets
Allegiant Air
Aug 1
MYR8:57 amMyrtle Beach Intl
1h 34m
SDF10:31 amLouisville Intl
Aug 15
SDF1:11 pmLouisville Intl
1h 32m
MYR2:43 pmMyrtle Beach Intl
$80
Allegiant Air
Aug 13
SAV6:16 pmSavannah/Hilton Head
1h 39m
SDF7:55 pmLouisville Intl
Aug 16
SDF8:45 pmLouisville Intl
1h 34m
SAV10:19 pmSavannah/Hilton Head
$82
Allegiant Air
Aug 13
SAV6:16 pmSavannah/Hilton Head
1h 39m
SDF7:55 pmLouisville Intl
Aug 16
SDF8:45 pmLouisville Intl
1h 34m
SAV10:19 pmSavannah/Hilton Head
$84

Southwest flights from South Carolina to Louisville

Our best Southwest deals on South Carolina to Louisville flight tickets
Southwest
Oct 23
CHS8:05 pmCharleston
4h 05m
1 stop
SDF12:10 amLouisville Intl
Oct 26
SDF8:20 amLouisville Intl
9h 40m
2 stops
CHS6:00 pmCharleston
$242
Southwest
Aug 11
GSP7:00 amGreenville
8h 15m
2 stops
SDF3:15 pmLouisville Intl
Aug 25
SDF7:05 amLouisville Intl
5h 20m
1 stop
GSP12:25 pmGreenville
$278
Southwest
Aug 11
GSP7:00 amGreenville
8h 15m
2 stops
SDF3:15 pmLouisville Intl
Aug 25
SDF1:15 pmLouisville Intl
7h 40m
2 stops
GSP8:55 pmGreenville
$283

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 23, 2026.
Use the filters below to find and compare flights from South Carolina to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Thu 8/13

6:16 pm-7:55 pm

Nonstop1h 39m

Louisville Intl

Sun 8/16

8:45 pm-10:19 pm

Nonstop1h 34m

$82

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Thu 8/13

6:16 pm-7:55 pm

Nonstop1h 39m

Louisville Intl

Sun 8/16

8:45 pm-10:19 pm

Nonstop1h 34m

$84

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 10/23

6:10 am-8:02 am

Nonstop1h 52m

Louisville Intl

Mon 10/26

7:59 pm-9:34 pm

Nonstop1h 35m

$122

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 10/23

6:10 am-8:02 am

Nonstop1h 52m

Louisville Intl

Mon 10/26

7:59 pm-9:34 pm

Nonstop1h 35m

$128

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Thu 8/13

6:16 pm-7:55 pm

Nonstop1h 39m

Louisville Intl

Sun 8/16

6:55 pm-12:22 pm

1 stop17h 27m

$138

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Thu 8/13

6:16 pm-7:55 pm

Nonstop1h 39m

Louisville Intl

Sun 8/16

6:55 pm-12:22 pm

1 stop17h 27m

$148

Hilton Head IslandLouisville

HHH - SDF

HHHSDF

Hilton Head Island

Wed 8/19

3:27 pm-9:31 pm

1 stop6h 04m

Louisville Intl

Tue 8/25

6:05 am-11:09 am

1 stop5h 04m

$261

ColumbiaLouisville

CAE - SDF

CAESDF

Columbia Metropolitan

Sat 9/26

6:00 am-10:19 am

1 stop4h 19m

Louisville Intl

Tue 9/29

11:04 am-5:11 pm

1 stop6h 07m

$271

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Tue 8/11

5:19 pm-9:31 pm

1 stop4h 12m

Louisville Intl

Tue 8/25

2:36 pm-8:46 pm

1 stop6h 10m

$273

ColumbiaLouisville

CAE - SDF

CAESDF

Columbia Metropolitan

Sat 9/26

1:59 pm-7:30 pm

1 stop5h 31m

Louisville Intl

Fri 10/2

7:05 am-1:14 pm

1 stop6h 09m

$280

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Louisville from

How to get the cheapest flight ticket from South Carolina to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Louisville?

If you are unable to visit Louisville during the month of January, then departing from South Carolina during the month February is also very affordable. Most momondo users find prices during this month for around $313.

What is the cheapest day to depart on your flight to Louisville?

On average, the least expensive day to fly to Louisville from South Carolina is on a Monday. momondo users have found tickets for Monday departures for as low as $202. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from South Carolina to Louisville on a Friday will generally be more expensive and average around $291. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest South Carolina to Louisville Intl flight route?

Fly from Charleston to Louisville Intl for the best South Carolina - Louisville Intl flight prices

What cabin class options are available on South Carolina to Louisville flights?

There are 2 cabin classes available to choose from on South Carolina to Louisville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Louisville flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Louisville.

Cheap South Carolina to Louisville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Louisville

Best Price Found

$123

Fastest flight time

1h 34m

Direct flights

Every day

Airports in Louisville

1 airport
The best flight deal from South Carolina to Louisville found on momondo in the last 72 hours is $123
The fastest flight from South Carolina to Louisville takes 1h 34m
Direct flights go from South Carolina to Louisville every day.
There is 1 airport in Louisville. From South Carolina there are direct flights to Louisville Intl (SDF).
Search flight deals

Frequently asked questions about flying from South Carolina to Louisville

  • When did momondo last update prices for flights from South Carolina to Louisville Intl Airport?

    Prices for flights from South Carolina to Louisville Intl Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Louisville Intl Airport?

  • How old do you have to be to fly from South Carolina to Louisville Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The required travel and health documents for your Louisville Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Louisville Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from South Carolina to Louisville?

Best airlines flying from South Carolina to Louisville

Compare and see reviews for airlines that fly from South Carolina to Louisville with momondo
Airline
Rating
Free Cancellation
Price
Breeze AirwaysPriceFrom $51Free CancellationRating
8.2
300 reviews
Search Breeze Airways flights
DeltaPriceFrom $128Free CancellationRating
7.8
8,480 reviews
Search Delta flights
American AirlinesPriceFrom $196Free CancellationRating
7.1
11,833 reviews
Search American Airlines flights

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
Jeffersonville
West Baden Springs
Bardstown
New Albany
Shepherdsville
Elizabeth
Corydon
Charlestown
Brandenburg
Georgetown
Springfield

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Louisville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Louisville. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Louisville with flexible booking policies on momondo?

All flight searches from South Carolina to Louisville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Louisville?

Once you have performed a search for South Carolina to Louisville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Louisville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from South Carolina to Louisville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Louisville and let you know when they change.

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