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Cheap flights from South Carolina to Santo Domingo from $114

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Santo Domingo departing on 12/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
7:00 am - 3:35 pmCLT-SDQ
7h 35m1 stop
Spirit Airlines Logo
4:40 pm - 12:40 amSDQ-CLT
9h 00m1 stop
$292Spirit Airlines
Find Deal
jue., ene. 29 - lun., feb. 2
Spirit Airlines Logo
5:45 am - 5:50 pmCLT-SDQ
11h 05m1 stop
Spirit Airlines Logo
6:55 pm - 12:59 amSDQ-CLT
7h 04m1 stop
$306Spirit Airlines
Find Deal
jue., ene. 29 - mar., feb. 10
American Airlines Logo
6:00 am - 12:28 pmCHS-SDQ
5h 28m1 stop
American Airlines Logo
6:23 pm - 8:45 amSDQ-CHS
15h 22m1 stop
$318American Airlines
Find Deal
jue., dic. 4 - jue., dic. 11
American Airlines Logo
7:56 pm - 12:15 pmCHS-SDQ
15h 19m1 stop
American Airlines Logo
1:28 pm - 11:13 pmSDQ-CHS
10h 45m2 stops
$322American Airlines
Find Deal
lun., dic. 1 - vie., dic. 12
Multiple Airlines Logo
8:28 am - 4:26 pmSAV-SDQ
30h 58m1 stop
Multiple Airlines Logo
4:35 pm - 11:03 pmSDQ-SAV
7h 28m1 stop
$323Multiple Airlines
Find Deal
mar., nov. 18 - vie., nov. 21
Multiple Airlines Logo
9:49 pm - 3:23 pmCHS-SDQ
16h 34m1 stop
Multiple Airlines Logo
7:10 pm - 11:00 amSDQ-CHS
16h 50m1 stop
$351Multiple Airlines
Find Deal
jue., dic. 4 - jue., dic. 11
JetBlue Logo
2:43 pm - 2:22 amCHS-SDQ
10h 39m1 stop
JetBlue Logo
4:10 am - 1:48 pmSDQ-CHS
10h 38m1 stop
$386JetBlue
Find Deal
jue., dic. 4 - mié., dic. 10
JetBlue Logo
4:43 pm - 2:17 pmCHS-SDQ
21h 34m1 stop
JetBlue Logo
10:59 pm - 11:19 amSDQ-CHS
12h 20m1 stop
$425JetBlue
Find Deal
sáb., mar. 14 - sáb., mar. 21
Delta Logo
12:00 pm - 11:59 pmCHS-SDQ
10h 59m1 stop
Delta Logo
7:05 am - 5:12 pmSDQ-CHS
11h 07m1 stop
$444Delta
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mar., mar. 3 - jue., mar. 5
Delta Logo
7:30 am - 11:59 pmCHS-SDQ
15h 29m2 stops
Delta Logo
8:00 pm - 11:20 amSDQ-CHS
16h 20m1 stop
$448Delta
Find Deal
mar., mar. 3 - jue., mar. 5

Spirit Airlines flights from South Carolina to Santo Domingo

Our best Spirit Airlines deals on South Carolina to Santo Domingo flight tickets
Spirit Airlines
Jan 29
CLT7:00 amCharlotte Douglas
7h 35m
1 stop
SDQ3:35 pmSanto Domingo Las Americas
Feb 2
SDQ4:40 pmSanto Domingo Las Americas
9h 00m
1 stop
CLT12:40 amCharlotte Douglas
$292
Find similar
Spirit Airlines
Jan 29
CLT5:45 amCharlotte Douglas
11h 05m
1 stop
SDQ5:50 pmSanto Domingo Las Americas
Feb 10
SDQ6:55 pmSanto Domingo Las Americas
7h 04m
1 stop
CLT12:59 amCharlotte Douglas
$306
Find similar
Spirit Airlines
Feb 4
CLT7:00 amCharlotte Douglas
7h 35m
1 stop
SDQ3:35 pmSanto Domingo Las Americas
Feb 7
SDQ4:40 pmSanto Domingo Las Americas
9h 00m
1 stop
CLT12:40 amCharlotte Douglas
$309
Find similar

Delta flights from South Carolina to Santo Domingo

Our best Delta deals on South Carolina to Santo Domingo flight tickets
Delta
Mar 3
CHS12:00 pmCharleston
10h 59m
1 stop
SDQ11:59 pmSanto Domingo Las Americas
Mar 5
SDQ7:05 amSanto Domingo Las Americas
11h 07m
1 stop
CHS5:12 pmCharleston
$444
Find similar
Delta
Mar 3
CHS7:30 amCharleston
15h 29m
2 stops
SDQ11:59 pmSanto Domingo Las Americas
Mar 5
SDQ8:00 pmSanto Domingo Las Americas
16h 20m
1 stop
CHS11:20 amCharleston
$448
Find similar
Delta
Mar 3
GSP6:49 amGreenville
6h 26m
1 stop
SDQ2:15 pmSanto Domingo Las Americas
Mar 6
SDQ7:05 amSanto Domingo Las Americas
15h 35m
2 stops
GSP9:40 pmGreenville
$522
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from South Carolina to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

jue. 1/29

7:00 am-3:35 pm

1 stop7h 35m

Santo Domingo Las Americas

lun. 2/2

4:40 pm-12:40 am

1 stop9h 00m

$292

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

jue. 1/29

5:45 am-5:50 pm

1 stop11h 05m

Santo Domingo Las Americas

mar. 2/10

6:55 pm-12:59 am

1 stop7h 04m

$306

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

jue. 12/4

6:00 am-12:28 pm

1 stop5h 28m

Santo Domingo Las Americas

jue. 12/11

6:23 pm-8:45 am

1 stop15h 22m

$318

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

lun. 12/1

7:56 pm-12:15 pm

1 stop15h 19m

Santo Domingo Las Americas

vie. 12/12

1:28 pm-11:13 pm

2 stops10h 45m

$322

SavannahSanto Domingo

SAV - SDQ

SAVSDQ

Savannah/Hilton Head

mar. 11/18

8:28 am-4:26 pm

1 stop30h 58m

Santo Domingo Las Americas

vie. 11/21

4:35 pm-11:03 pm

1 stop7h 28m

$323

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

jue. 12/4

9:49 pm-3:23 pm

1 stop16h 34m

Santo Domingo Las Americas

jue. 12/11

7:10 pm-11:00 am

1 stop16h 50m

$351

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

jue. 12/4

2:43 pm-2:22 am

1 stop10h 39m

Santo Domingo Las Americas

mié. 12/10

4:10 am-1:48 pm

1 stop10h 38m

$386

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

sáb. 3/14

4:43 pm-2:17 pm

1 stop21h 34m

Santo Domingo Las Americas

sáb. 3/21

10:59 pm-11:19 am

1 stop12h 20m

$425

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

mar. 3/3

12:00 pm-11:59 pm

1 stop10h 59m

Santo Domingo Las Americas

jue. 3/5

7:05 am-5:12 pm

1 stop11h 07m

$444

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

mar. 3/3

7:30 am-11:59 pm

2 stops15h 29m

Santo Domingo Las Americas

jue. 3/5

8:00 pm-11:20 am

1 stop16h 20m

$448

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from South Carolina to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in November, then you should wait until January to fly from South Carolina, when ticket prices are also cheap, with an average price of $410.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Wednesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $391. The most expensive day to fly to Santo Domingo is Monday, with ticket prices averaging around $760.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is at noon when flights can be purchased for as low as $257. Try not to purchase tickets in the afternoon because they tend to be around $637. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on South Carolina to Santo Domingo flights?

You could potentially save up to 39% on your flight if you consider stops on a South Carolina to Santo Domingo flight.

Cheap South Carolina to Santo Domingo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Santo Domingo

Direct flights

None
There are no direct flights from South Carolina to Santo Domingo. There are no popular flight routes from South Carolina to Santo Domingo.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Santo Domingo Las Americas Airport?

    Prices for flights from South Carolina to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from South Carolina to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Santo Domingo

Compare and see reviews for airlines that fly from South Carolina to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $327Free CancellationRating
6.3
8,122 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $338Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
DeltaPriceFrom $420Free CancellationRating
7.9
8,001 reviews
Search Delta flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Santo Domingo?

It is quick and easy to find South Carolina to Santo Domingo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santo Domingo that suits you.

Can I find flights from South Carolina to Santo Domingo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to Santo Domingo flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from South Carolina.

I’m not ready to book a flight from South Carolina to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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