What is the cheapest airline that flies from South Carolina to Indianapolis?

Frontier, Spirit Airlines, and Allegiant Air are the most popular carriers operating from South Carolina to Indianapolis

How many flights depart from South Carolina to Indianapolis on average per week?

As of November 2025, 27 flights take off from South Carolina and land in Indianapolis each week. The most common flight departure day for this route is Tue, with 22% of weekly flights taking off on this day.

How long does it take to fly to Indianapolis?

Flight times from South Carolina to Indianapolis vary, but if you’re flying out of Charleston and flying into Cincinnati (one of the most popular routes), then the duration is 1h 41m on average. Another popular route from South Carolina to Indianapolis is flying from Columbia to Cincinnati, which will take roughly 3h 21m. Keep in mind that layovers or delays could extend your travel time.

What airlines fly to Indianapolis?

American Airlines, Delta and Allegiant Air are the top three most popular airlines that fly to Indianapolis from South Carolina according to our data. American Airlines is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Indianapolis. Keep in mind that there are 7 different airlines that fly to Indianapolis on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from South Carolina to Indianapolis Airport?

Prices for flights from South Carolina to Indianapolis Airport refresh daily.

How many operators does momondo search for flights from South Carolina to Indianapolis Airport?

The number of operators available for flights from South Carolina to Indianapolis Airport is 7 as of November 2025.

How old do you have to be to fly from South Carolina to Indianapolis Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Indianapolis Airport.

What documentation or ID do you need to fly to Indianapolis Airport?

The required travel and health documents for your Indianapolis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Indianapolis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$81 Cheap Flights from South Carolina to Indianapolis in 2025/26

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Cheap round-trip flights

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12:17 pm - 7:53 pmCLT-IND

7h 36m1 stop

10:36 am - 9:06 pmIND-CLT

10h 30m1 stop

$162Frontier

Find Deal

Sat, Mar 7 - Mon, Mar 9

2:15 pm - 9:35 pmMYR-IND

7h 20m1 stop

5:30 am - 1:20 pmIND-MYR

7h 50m1 stop

$173Spirit Airlines

Find Deal

Fri, Dec 12 - Mon, Dec 15

10:33 pm - 10:36 amCLT-IND

12h 03m1 stop

12:03 pm - 11:59 pmIND-CLT

11h 56m1 stop

$196Multiple Airlines

Find Deal

Thu, Dec 11 - Sat, Dec 13

8:55 am - 10:58 amCLT-IND

26h 03m1 stop

1:07 pm - 11:59 pmIND-CLT

10h 52m2 stops

$208Multiple Airlines

Find Deal

Tue, Dec 9 - Sat, Dec 13

6:59 pm - 12:06 amCAE-IND

5h 07m1 stop

3:35 pm - 9:28 pmIND-CAE

5h 53m1 stop

$229Delta

Find Deal

Fri, Jan 23 - Mon, Jan 26

5:20 am - 9:33 amGSP-IND

4h 13m1 stop

6:51 am - 12:21 pmIND-GSP

5h 30m1 stop

$235American Airlines

Find Deal

Mon, Mar 2 - Wed, Mar 4

6:50 am - 10:36 amAGS-IND

3h 46m1 stop

3:29 pm - 8:26 pmIND-AGS

4h 57m1 stop

$247Delta

Find Deal

Tue, Feb 10 - Sat, Feb 14

6:35 pm - 11:05 pmGSP-IND

4h 30m1 stop

10:30 am - 5:40 pmIND-GSP

7h 10m2 stops

$263Southwest

Find Deal

Mon, Mar 2 - Wed, Mar 4

3:37 pm - 11:58 pmCAE-IND

8h 21m1 stop

5:32 pm - 12:07 amIND-CAE

6h 35m1 stop

$265American Airlines

Find Deal

Tue, Dec 30 - Thu, Jan 1

10:45 am - 10:50 pmGSP-IND

12h 05m2 stops

10:30 am - 5:40 pmIND-GSP

7h 10m2 stops

$274Southwest

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Mon, Mar 2 - Wed, Mar 4

Delta flights from South Carolina to Indianapolis

Our best Delta deals on South Carolina to Indianapolis flight tickets

Delta

Nov 27

CAE6:38 amColumbia Metropolitan

3h 32m

1 stop

IND10:10 amIndianapolis

Nov 27

IND2:20 pmIndianapolis

4h 44m

1 stop

CAE7:04 pmColumbia Metropolitan

$191

Find similar

Delta

Jan 23

CAE6:59 pmColumbia Metropolitan

5h 07m

1 stop

IND12:06 amIndianapolis

Jan 26

IND3:35 pmIndianapolis

5h 53m

1 stop

CAE9:28 pmColumbia Metropolitan

$229

Find similar

Delta

Nov 27

CAE12:56 pmColumbia Metropolitan

5h 54m

1 stop

IND6:50 pmIndianapolis

Dec 2

IND6:00 amIndianapolis

4h 12m

1 stop

CAE10:12 amColumbia Metropolitan

$245

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American Airlines flights from South Carolina to Indianapolis

Our best American Airlines deals on South Carolina to Indianapolis flight tickets

American Airlines

Mar 2

GSP5:20 amGreenville

4h 13m

1 stop

IND9:33 amIndianapolis

Mar 4

IND6:51 amIndianapolis

5h 30m

1 stop

GSP12:21 pmGreenville

$235

Find similar

American Airlines

Dec 30

CAE3:37 pmColumbia Metropolitan

8h 21m

1 stop

IND11:58 pmIndianapolis

Jan 1

IND5:32 pmIndianapolis

6h 35m

1 stop

CAE12:07 amColumbia Metropolitan

$265

Find similar

American Airlines

Dec 19

CAE5:16 amColumbia Metropolitan

4h 06m

1 stop

IND9:22 amIndianapolis

Dec 24

IND6:03 amIndianapolis

4h 39m

1 stop

CAE10:42 amColumbia Metropolitan

$280

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momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Sat 3/7

12:17 pm-7:53 pm

1 stop7h 36m

Indianapolis

Mon 3/9

10:36 am-9:06 pm

1 stop10h 30m

$162

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 12/12

2:15 pm-9:35 pm

1 stop7h 20m

Indianapolis

Mon 12/15

5:30 am-1:20 pm

1 stop7h 50m

$173

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 12/11

10:33 pm-10:36 am

1 stop12h 03m

Indianapolis

Sat 12/13

12:03 pm-11:59 pm

1 stop11h 56m

$196

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Tue 12/9

8:55 am-10:58 am

1 stop26h 03m

Indianapolis

Sat 12/13

1:07 pm-11:59 pm

2 stops10h 52m

$208

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Fri 1/23

6:59 pm-12:06 am

1 stop5h 07m

Indianapolis

Mon 1/26

3:35 pm-9:28 pm

1 stop5h 53m

$229

GreenvilleIndianapolis

GSP - IND

GSPIND

Greenville

Mon 3/2

5:20 am-9:33 am

1 stop4h 13m

Indianapolis

Wed 3/4

6:51 am-12:21 pm

1 stop5h 30m

$235

AugustaIndianapolis

AGS - IND

AGSIND

Augusta Bush Field

Tue 2/10

6:50 am-10:36 am

1 stop3h 46m

Indianapolis

Sat 2/14

3:29 pm-8:26 pm

1 stop4h 57m

$247

GreenvilleIndianapolis

GSP - IND

GSPIND

Greenville

Mon 3/2

6:35 pm-11:05 pm

1 stop4h 30m

Indianapolis

Wed 3/4

10:30 am-5:40 pm

2 stops7h 10m

$263

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Tue 12/30

3:37 pm-11:58 pm

1 stop8h 21m

Indianapolis

Thu 1/1

5:32 pm-12:07 am

1 stop6h 35m

$265

GreenvilleIndianapolis

GSP - IND

GSPIND

Greenville

Mon 3/2

10:45 am-10:50 pm

2 stops12h 05m

Indianapolis

Wed 3/4

10:30 am-5:40 pm

2 stops7h 10m

$274

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Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Indianapolis?

In general, July is the cheapest month to fly from South Carolina to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $240. If you are unable to visit Indianapolis during the month of July, then departing from South Carolina during the month May is also very affordable. Most momondo users find prices during this month for around $290.

What is the cheapest day to depart on your flight to Indianapolis?

Our data shows that Friday is the least expensive day to fly to Indianapolis. Tickets to fly out on this day can be as low as $146. Be sure to avoid booking your departure on a Tuesday as prices are generally higher than usual. According to our data, the average ticket price to Indianapolis on Tuesday is $309.

What is the cheapest South Carolina to Indianapolis flight route?

Fly from Myrtle Beach Intl to Indianapolis for the best South Carolina - Indianapolis flight prices

How far in advance should I book a flight to Indianapolis?

You are more likely to see cheaper flights to Indianapolis from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Indianapolis for around $358 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Indianapolis from South Carolina for as low as $232 on momondo.

What cabin class options are available on South Carolina to Indianapolis flights?

There is only 1 cabin class available to choose from on South Carolina to Indianapolis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Indianapolis flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Indianapolis.

Cheap South Carolina to Indianapolis flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Indianapolis

Fastest flight time	1h 36m
Direct flights	Every day
Airports in Indianapolis	1 airport

The fastest flight from South Carolina to Indianapolis takes 1h 36m

Direct flights go from South Carolina to Indianapolis every day.

There is 1 airport near Indianapolis: Indianapolis (IND)

Search flight deals

When did momondo last update prices for flights from South Carolina to Indianapolis Airport?
Prices for flights from South Carolina to Indianapolis Airport refresh daily.
How many operators does momondo search for flights from South Carolina to Indianapolis Airport?
The number of operators available for flights from South Carolina to Indianapolis Airport is 7 as of November 2025.
How old do you have to be to fly from South Carolina to Indianapolis Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Indianapolis Airport.
What documentation or ID do you need to fly to Indianapolis Airport?
The required travel and health documents for your Indianapolis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Indianapolis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from South Carolina to Indianapolis?
momondo data reveals that the most frequently booked plane model on the route from South Carolina to Indianapolis is Airbus A320-100/200, representing 66.67% of all bookings. The subsequent popular model is Airbus A319 at 33.33%.

Best airlines flying from South Carolina to Indianapolis

Compare and see reviews for airlines that fly from South Carolina to Indianapolis with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $45	Free Cancellation	Rating 7.2 701 reviews	Search Allegiant Air flights
Spirit Airlines	PriceFrom $146	Free Cancellation	Rating 6.3 8,159 reviews	Search Spirit Airlines flights
Southwest	PriceFrom $189	Free Cancellation	Rating 8.0 4,252 reviews	Search Southwest flights
United Airlines	PriceFrom $190	Free Cancellation	Rating 7.4 9,036 reviews	Search United Airlines flights
Delta	PriceFrom $216	Free Cancellation	Rating 7.9 7,997 reviews	Search Delta flights
American Airlines	PriceFrom $228	Free Cancellation	Rating 7.2 11,046 reviews	Search American Airlines flights

Terre Haute

Bloomington

Kokomo

Muncie

Anderson

Plainfield

Greenwood

Noblesville

Fishers

Carmel

Shelbyville

West Lafayette

Seymour

Franklin

Speedway

Crawfordsville

Brownsburg

Greenfield

Westfield

Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Indianapolis?

It is quick and easy to find South Carolina to Indianapolis flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Indianapolis that suits you.

Can I find flights from South Carolina to Indianapolis with flexible booking policies on momondo?

Yes. All flights to Indianapolis from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Indianapolis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Indianapolis from South Carolina.

I’m not ready to book a flight from South Carolina to Indianapolis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Indianapolis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from South Carolina to Indianapolis from $81

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Indianapolis departing on 2/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Delta flights from South Carolina to Indianapolis

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Use the filters below to find and compare flights from South Carolina to Indianapolis that are best for you.

See travel insights to Indianapolis from

How to get the cheapest flight ticket from South Carolina to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Indianapolis?

What is the cheapest day to depart on your flight to Indianapolis?

What is the cheapest South Carolina to Indianapolis flight route?

Fly from Myrtle Beach Intl to Indianapolis for the best South Carolina - Indianapolis flight prices

How far in advance should I book a flight to Indianapolis?

What cabin class options are available on South Carolina to Indianapolis flights?

There is only 1 cabin class available to choose from on South Carolina to Indianapolis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Indianapolis flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Indianapolis.

What is the cheapest airline that flies from South Carolina to Indianapolis?

Frontier, Spirit Airlines, and Allegiant Air are the most popular carriers operating from South Carolina to Indianapolis

What airlines fly to Indianapolis?

How many flights depart from South Carolina to Indianapolis on average per week?

As of November 2025, 27 flights take off from South Carolina and land in Indianapolis each week. The most common flight departure day for this route is Tue, with 22% of weekly flights taking off on this day.

How long does it take to fly to Indianapolis?

Cheap South Carolina to Indianapolis flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Indianapolis

Fastest flight time

Direct flights

Airports in Indianapolis

When did momondo last update prices for flights from South Carolina to Indianapolis Airport?

How many operators does momondo search for flights from South Carolina to Indianapolis Airport?

How old do you have to be to fly from South Carolina to Indianapolis Airport?

What documentation or ID do you need to fly to Indianapolis Airport?

What is the most popular plane model from South Carolina to Indianapolis?

Best airlines flying from South Carolina to Indianapolis

Compare and see reviews for airlines that fly from South Carolina to Indianapolis with momondo

Traveling to a place near Indianapolis?

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Indianapolis?

Can I find flights from South Carolina to Indianapolis with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to Indianapolis?

I’m not ready to book a flight from South Carolina to Indianapolis right now. Can momondo alert me if prices change?

An easier way to manage your Indianapolis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Indiana