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Cheap flights from South Carolina to Indianapolis from $72

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Indianapolis departing on 10/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Indianapolis

Cheap round-trip flights

Spirit Airlines Logo
8:52 am - 5:07 pmCLT-IND
8h 15m1 stop
Spirit Airlines Logo
5:15 am - 1:35 pmIND-CLT
8h 20m1 stop
$148Spirit Airlines
Find Deal
Tue, Oct 21 - Wed, Oct 22
Multiple Airlines Logo
5:38 pm - 7:21 pmCLT-IND
1h 43mnonstop
Multiple Airlines Logo
10:06 pm - 8:00 amIND-CLT
9h 54m1 stop
$156Multiple Airlines
Find Deal
Thu, Oct 16 - Sun, Oct 19
Frontier Logo
5:34 pm - 4:29 pmCLT-IND
22h 55m1 stop
Frontier Logo
7:36 pm - 8:00 amIND-CLT
12h 24m1 stop
$162Frontier
Find Deal
Fri, Oct 24 - Sun, Oct 26
Frontier Logo
11:54 am - 9:32 pmCLT-IND
9h 38m1 stop
Frontier Logo
10:14 pm - 8:00 amIND-CLT
9h 46m1 stop
$167Frontier
Find Deal
Mon, Oct 13 - Sat, Oct 18
American Airlines Logo
8:50 pm - 10:39 pmCLT-IND
1h 49mnonstop
American Airlines Logo
7:00 pm - 8:49 pmIND-CLT
1h 49mnonstop
$181American Airlines
Find Deal
Thu, Nov 6 - Tue, Nov 11
American Airlines Logo
4:39 pm - 10:02 pmCLT-IND
5h 23m1 stop
American Airlines Logo
6:00 am - 7:50 amIND-CLT
1h 50mnonstop
$201American Airlines
Find Deal
Thu, Nov 6 - Tue, Nov 11
United Airlines Logo
4:56 pm - 9:56 pmSAV-IND
5h 00m1 stop
United Airlines Logo
4:36 pm - 9:47 pmIND-SAV
5h 11m1 stop
$237United Airlines
Find Deal
Wed, Oct 15 - Mon, Oct 20
Delta Logo
5:45 am - 10:03 amAGS-IND
4h 18m1 stop
Delta Logo
6:25 pm - 11:53 pmIND-AGS
5h 28m1 stop
$247Delta
Find Deal
Sat, Feb 21 - Tue, Feb 24
Delta Logo
5:30 am - 8:55 amGSP-IND
3h 25m1 stop
Delta Logo
6:51 pm - 11:55 pmIND-GSP
5h 04m1 stop
$257Delta
Find Deal
Thu, Oct 16 - Sat, Oct 18
United Airlines Logo
7:48 pm - 11:59 pmCAE-IND
4h 11m1 stop
United Airlines Logo
6:00 am - 10:23 amIND-CAE
4h 23m1 stop
$270United Airlines
Find Deal
Sat, Sep 27 - Sun, Sep 28

Frontier flights from South Carolina to Indianapolis

Our best Frontier deals on South Carolina to Indianapolis flight tickets
Frontier
Oct 24
CLT5:34 pmCharlotte Douglas
22h 55m
1 stop
IND4:29 pmIndianapolis
Oct 26
IND7:36 pmIndianapolis
12h 24m
1 stop
CLT8:00 amCharlotte Douglas
$162
Find similar
Frontier
Oct 13
CLT11:54 amCharlotte Douglas
9h 38m
1 stop
IND9:32 pmIndianapolis
Oct 18
IND10:14 pmIndianapolis
9h 46m
1 stop
CLT8:00 amCharlotte Douglas
$167
Find similar
Frontier
Oct 3
CLT12:17 pmCharlotte Douglas
6h 27m
1 stop
IND6:44 pmIndianapolis
Oct 6
IND10:47 amIndianapolis
8h 18m
1 stop
CLT7:05 pmCharlotte Douglas
$168
Find similar

Spirit Airlines flights from South Carolina to Indianapolis

Our best Spirit Airlines deals on South Carolina to Indianapolis flight tickets
Spirit Airlines
Oct 21
CLT8:52 amCharlotte Douglas
8h 15m
1 stop
IND5:07 pmIndianapolis
Oct 22
IND5:15 amIndianapolis
8h 20m
1 stop
CLT1:35 pmCharlotte Douglas
$148
Find similar
Spirit Airlines
Oct 6
CLT10:06 pmCharlotte Douglas
11h 14m
1 stop
IND9:20 amIndianapolis
Oct 9
IND7:06 pmIndianapolis
1h 45m
CLT8:51 pmCharlotte Douglas
$165
Find similar
Spirit Airlines
Oct 20
CHS9:10 pmCharleston
19h 57m
1 stop
IND5:07 pmIndianapolis
Oct 25
IND8:55 amIndianapolis
9h 46m
1 stop
CHS6:41 pmCharleston
$167
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 23, 2025.
Use the filters below to find and compare flights from South Carolina to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Tue 10/21

8:52 am-5:07 pm

1 stop8h 15m

Indianapolis

Wed 10/22

5:15 am-1:35 pm

1 stop8h 20m

$148

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 10/16

5:38 pm-7:21 pm

Nonstop1h 43m

Indianapolis

Sun 10/19

10:06 pm-8:00 am

1 stop9h 54m

$156

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Fri 10/24

5:34 pm-4:29 pm

1 stop22h 55m

Indianapolis

Sun 10/26

7:36 pm-8:00 am

1 stop12h 24m

$162

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Mon 10/13

11:54 am-9:32 pm

1 stop9h 38m

Indianapolis

Sat 10/18

10:14 pm-8:00 am

1 stop9h 46m

$167

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 11/6

8:50 pm-10:39 pm

Nonstop1h 49m

Indianapolis

Tue 11/11

7:00 pm-8:49 pm

Nonstop1h 49m

$181

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 11/6

4:39 pm-10:02 pm

1 stop5h 23m

Indianapolis

Tue 11/11

6:00 am-7:50 am

Nonstop1h 50m

$201

SavannahIndianapolis

SAV - IND

SAVIND

Savannah/Hilton Head

Wed 10/15

4:56 pm-9:56 pm

1 stop5h 00m

Indianapolis

Mon 10/20

4:36 pm-9:47 pm

1 stop5h 11m

$237

AugustaIndianapolis

AGS - IND

AGSIND

Augusta Bush Field

Sat 2/21

5:45 am-10:03 am

1 stop4h 18m

Indianapolis

Tue 2/24

6:25 pm-11:53 pm

1 stop5h 28m

$247

GreenvilleIndianapolis

GSP - IND

GSPIND

Greenville

Thu 10/16

5:30 am-8:55 am

1 stop3h 25m

Indianapolis

Sat 10/18

6:51 pm-11:55 pm

1 stop5h 04m

$257

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Sat 9/27

7:48 pm-11:59 pm

1 stop4h 11m

Indianapolis

Sun 9/28

6:00 am-10:23 am

1 stop4h 23m

$270

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Indianapolis from

How to get the cheapest flight ticket from South Carolina to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Indianapolis?

In general, July is the cheapest month to fly from South Carolina to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $240. If you are unable to visit Indianapolis during the month of July, then departing from South Carolina during the month May is also very affordable. Most momondo users find prices during this month for around $290.

What is the cheapest day to depart on your flight to Indianapolis?

Our data shows that Friday is the least expensive day to fly to Indianapolis. Tickets to fly out on this day can be as low as $146. Be sure to avoid booking your departure on a Tuesday as prices are generally higher than usual. According to our data, the average ticket price to Indianapolis on Tuesday is $309.

What is the cheapest South Carolina to Indianapolis flight route?

Fly from Myrtle Beach Intl to Indianapolis for the best South Carolina - Indianapolis flight prices

How far in advance should I book a flight to Indianapolis?

You are more likely to see cheaper flights to Indianapolis from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Indianapolis for around $362 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Indianapolis from South Carolina for as low as $260 on momondo.

What cabin class options are available on South Carolina to Indianapolis flights?

There is only 1 cabin class available to choose from on South Carolina to Indianapolis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Indianapolis flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Indianapolis.

Cheap South Carolina to Indianapolis flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Indianapolis

Fastest flight time

1h 36m

Direct flights

Every day

Airports in Indianapolis

1 airport
The fastest flight from South Carolina to Indianapolis takes 1h 36m
Direct flights go from South Carolina to Indianapolis every day.
There is 1 airport near Indianapolis: Indianapolis (IND)
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Indianapolis Airport?

    Prices for flights from South Carolina to Indianapolis Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Indianapolis Airport?

  • How old do you have to be to fly from South Carolina to Indianapolis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The required travel and health documents for your Indianapolis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Indianapolis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from South Carolina to Indianapolis?

Best airlines flying from South Carolina to Indianapolis

Compare and see reviews for airlines that fly from South Carolina to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $45Free CancellationRating
7.2
699 reviews
Search Allegiant Air flights
Spirit AirlinesPriceFrom $149Free CancellationRating
6.3
8,041 reviews
Search Spirit Airlines flights
SouthwestPriceFrom $189Free CancellationRating
8.0
4,244 reviews
Search Southwest flights
United AirlinesPriceFrom $190Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
DeltaPriceFrom $212Free CancellationRating
7.9
7,974 reviews
Search Delta flights
American AirlinesPriceFrom $228Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Anderson
Plainfield
Greenwood
Noblesville
Fishers
Carmel
Shelbyville
Seymour
West Lafayette
Franklin
Brownsburg
Crawfordsville
Speedway
Greenfield
Westfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Indianapolis?

It is quick and easy to find South Carolina to Indianapolis flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Indianapolis that suits you.

Can I find flights from South Carolina to Indianapolis with flexible booking policies on momondo?

Yes. All flights to Indianapolis from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Indianapolis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Indianapolis from South Carolina.

I’m not ready to book a flight from South Carolina to Indianapolis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Indianapolis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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