How long does it take to fly to Buffalo?

On average, it takes 3h 15m to fly from South Carolina to Buffalo if you fly out of Myrtle Beach (the most popular airport in South Carolina) and into Buffalo (the most popular airport in Buffalo). If you’re flying out of Greenville and into Buffalo, then the flight time is around 3h 35m.

What is the cheapest airline that flies from South Carolina to Buffalo?

Delta, Southwest, and American Airlines are the most popular carriers operating from South Carolina to Buffalo

What airlines fly to Buffalo?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Buffalo from South Carolina according to our data. American Airlines is the first choice among our users, with 51% of people opting to fly with this airline when traveling to Buffalo. Keep in mind that there are 5 different airlines that fly to Buffalo on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from South Carolina to Buffalo Airport?

Prices for flights from South Carolina to Buffalo Airport refresh daily.

How many operators does momondo search for flights from South Carolina to Buffalo Airport?

The number of operators available for flights from South Carolina to Buffalo Airport is 3 as of October 2026.

How old do you have to be to fly from South Carolina to Buffalo Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Buffalo Airport.

What documentation or ID do you need to fly to Buffalo Airport?

The necessary travel and health documents for your Buffalo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$118 Cheap Flights from South Carolina to Buffalo in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Buffalo

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:19 pm - 12:11 amCHS Charleston-BUF Buffalo

6h 52m1 stop New York John F Kennedy Intl

6:00 am - 12:59 pmBUF Buffalo-CHS Charleston

6h 59m1 stop Atlanta Hartsfield-Jackson

$235Delta

Mon, Nov 23 - Tue, Dec 1

6:00 am - 10:35 amCHS Charleston-BUF Buffalo

4h 35m1 stop New York John F Kennedy Intl

2:15 pm - 9:21 pmBUF Buffalo-CHS Charleston

7h 06m1 stop New York LaGuardia

$235Delta

Mon, Nov 23 - Wed, Dec 2

1:06 pm - 6:58 pmCHS Charleston-BUF Buffalo

5h 52m1 stop Detroit Metropolitan Wayne County

6:00 am - 12:59 pmBUF Buffalo-CHS Charleston

6h 59m1 stop Atlanta Hartsfield-Jackson

$235Delta

Thu, Nov 26 - Wed, Dec 2

5:04 am - 10:41 amCHS Charleston-BUF Buffalo

5h 37m1 stop Charlotte Douglas

6:52 pm - 10:51 pmBUF Buffalo-CHS Charleston

3h 59m1 stop Charlotte Douglas

$255American Airlines

Fri, Dec 4 - Tue, Dec 8

1:30 pm - 6:10 pmCHS Charleston-BUF Buffalo

4h 40m1 stop Baltimore/Washington

8:05 am - 5:25 pmBUF Buffalo-CHS Charleston

9h 20m2 stops Chicago Midway Nashville Intl

$260Southwest

Fri, Dec 4 - Tue, Dec 8

7:00 am - 10:42 amGSP Greenville-BUF Buffalo

3h 42m1 stop Charlotte Douglas

6:09 pm - 10:54 pmBUF Buffalo-GSP Greenville

4h 45m1 stop New York LaGuardia

$271American Airlines

Thu, Nov 26 - Wed, Dec 2

7:00 am - 10:42 amGSP Greenville-BUF Buffalo

3h 42m1 stop Charlotte Douglas

7:44 pm - 11:31 pmBUF Buffalo-GSP Greenville

3h 47m1 stop Charlotte Douglas

$271American Airlines

Thu, Nov 26 - Tue, Dec 1

2:51 pm - 7:04 pmGSP Greenville-BUF Buffalo

4h 13m1 stop Washington, D.C. Dulles Intl

7:00 am - 4:53 pmBUF Buffalo-GSP Greenville

9h 53m2 stops Newark Chicago O'Hare Intl

$276United Airlines

Thu, Nov 26 - Thu, Dec 3

2:51 pm - 7:04 pmGSP Greenville-BUF Buffalo

4h 13m1 stop Washington, D.C. Dulles Intl

7:00 am - 4:53 pmBUF Buffalo-GSP Greenville

9h 53m2 stops Newark Chicago O'Hare Intl

$276United Airlines

Thu, Nov 26 - Wed, Dec 2

5:35 pm - 9:45 pmCHS Charleston-BUF Buffalo

4h 10m1 stop Baltimore/Washington

5:45 am - 10:10 amBUF Buffalo-CHS Charleston

4h 25m1 stop Baltimore/Washington

$281Southwest

Fri, Jan 29 - Mon, Feb 1

Cheap last minute flights

Enter your travel dates to find the best prices.

11:30 am - 5:28 pmCHS Charleston-BUF Buffalo

5h 58m1 stop New York LaGuardia

6:36 pm - 11:59 pmBUF Buffalo-CHS Charleston

5h 23m1 stop Atlanta Hartsfield-Jackson

$478Delta

Wed, Nov 4 - Mon, Nov 9

12:18 pm - 10:59 pmCHS Charleston-BUF Buffalo

10h 41m2 stops Chicago O'Hare Intl Newark

6:00 am - 10:06 amBUF Buffalo-CHS Charleston

4h 06m1 stop Washington, D.C. Dulles Intl

$483United Airlines

Wed, Nov 4 - Mon, Nov 9

7:00 am - 2:20 pmCHS Charleston-BUF Buffalo

7h 20m2 stops Newark Washington, D.C. Dulles Intl

6:00 am - 2:28 pmBUF Buffalo-CHS Charleston

8h 28m2 stops Newark Washington, D.C. Dulles Intl

$488United Airlines

Wed, Nov 4 - Mon, Nov 9

10:52 am - 4:04 pmMYR Myrtle Beach Intl-BUF Buffalo

5h 12m1 stop Atlanta Hartsfield-Jackson

12:16 pm - 6:01 pmBUF Buffalo-MYR Myrtle Beach Intl

5h 45m1 stop Atlanta Hartsfield-Jackson

$535Delta

Wed, Nov 4 - Wed, Nov 11

10:52 am - 4:04 pmMYR Myrtle Beach Intl-BUF Buffalo

5h 12m1 stop Atlanta Hartsfield-Jackson

6:00 am - 10:07 amBUF Buffalo-MYR Myrtle Beach Intl

4h 07m1 stop Atlanta Hartsfield-Jackson

$535Delta

Wed, Nov 4 - Thu, Nov 12

5:03 pm - 9:40 pmMYR Myrtle Beach Intl-BUF Buffalo

4h 37m1 stop Charlotte Douglas

12:58 pm - 4:23 pmBUF Buffalo-MYR Myrtle Beach Intl

3h 25m1 stop Charlotte Douglas

$553American Airlines

Wed, Nov 4 - Tue, Nov 10

5:28 pm - 9:40 pmCHS Charleston-BUF Buffalo

4h 12m1 stop Charlotte Douglas

3:26 pm - 8:42 pmBUF Buffalo-CHS Charleston

5h 16m1 stop Philadelphia

$589American Airlines

Wed, Nov 4 - Sat, Nov 7

9:40 am - 2:58 pmCHS Charleston-BUF Buffalo

5h 18m1 stop New York John F Kennedy Intl

12:08 pm - 7:31 pmBUF Buffalo-CHS Charleston

7h 23m1 stop New York John F Kennedy Intl

$590JetBlue

Mon, Nov 2 - Fri, Nov 6

11:00 am - 8:55 pmCHS Charleston-BUF Buffalo

9h 55m2 stops Nashville Intl Chicago Midway

1:10 pm - 8:10 pmBUF Buffalo-CHS Charleston

7h 00m1 stop Baltimore/Washington

$594Southwest

Wed, Nov 4 - Sat, Nov 7

1:30 pm - 10:20 pmCHS Charleston-BUF Buffalo

8h 50m2 stops Baltimore/Washington Orlando

1:10 pm - 8:10 pmBUF Buffalo-CHS Charleston

7h 00m1 stop Baltimore/Washington

$594Southwest

Tue, Nov 3 - Sat, Nov 7

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American Airlines flights from South Carolina to Buffalo

Our best American Airlines deals on South Carolina to Buffalo flight tickets

American Airlines

Dec 4

CHS5:04 amCharleston

5h 37m

1 stop

BUF10:41 amBuffalo

Dec 8

BUF6:52 pmBuffalo

3h 59m

1 stop

CHS10:51 pmCharleston

$255

American Airlines

Nov 25

CHS8:14 pmCharleston

3h 51m

1 stop

BUF12:05 amBuffalo

Dec 2

BUF12:12 pmBuffalo

5h 58m

1 stop

CHS6:10 pmCharleston

$295

American Airlines

Nov 23

CHS8:14 pmCharleston

3h 51m

1 stop

BUF12:05 amBuffalo

Nov 30

BUF7:44 pmBuffalo

4h 11m

1 stop

CHS11:55 pmCharleston

$305

Southwest flights from South Carolina to Buffalo

Our best Southwest deals on South Carolina to Buffalo flight tickets

Southwest

Dec 4

CHS1:30 pmCharleston

4h 40m

1 stop

BUF6:10 pmBuffalo

Dec 8

BUF8:05 amBuffalo

9h 20m

2 stops

CHS5:25 pmCharleston

$260

Southwest

Jan 21

CHS7:55 amCharleston

9h 30m

2 stops

BUF5:25 pmBuffalo

Jan 24

BUF7:45 amBuffalo

9h 00m

2 stops

CHS4:45 pmCharleston

$291

Southwest

Jan 13

GSP8:25 amGreenville

9h 00m

2 stops

BUF5:25 pmBuffalo

Jan 18

BUF10:50 amBuffalo

8h 35m

2 stops

GSP7:25 pmGreenville

$335

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Mon 11/23

5:19 pm-12:11 am

1 stop6h 52m

Buffalo

Tue 12/1

6:00 am-12:59 pm

1 stop6h 59m

$235

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Mon 11/23

6:00 am-10:35 am

1 stop4h 35m

Buffalo

Wed 12/2

2:15 pm-9:21 pm

1 stop7h 06m

$235

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Thu 11/26

1:06 pm-6:58 pm

1 stop5h 52m

Buffalo

Wed 12/2

6:00 am-12:59 pm

1 stop6h 59m

$235

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Fri 12/4

5:04 am-10:41 am

1 stop5h 37m

Buffalo

Tue 12/8

6:52 pm-10:51 pm

1 stop3h 59m

$255

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Fri 12/4

1:30 pm-6:10 pm

1 stop4h 40m

Buffalo

Tue 12/8

8:05 am-5:25 pm

2 stops9h 20m

$260

GreenvilleBuffalo

GSP Greenville - BUF Buffalo

GSPBUF

Greenville

Thu 11/26

7:00 am-10:42 am

1 stop3h 42m

Buffalo

Wed 12/2

6:09 pm-10:54 pm

1 stop4h 45m

$271

Quickest round-trip

GreenvilleBuffalo

GSP Greenville - BUF Buffalo

GSPBUF

Greenville

Thu 11/26

7:00 am-10:42 am

1 stop3h 42m

Buffalo

Tue 12/1

7:44 pm-11:31 pm

1 stop3h 47m

$271

GreenvilleBuffalo

GSP Greenville - BUF Buffalo

GSPBUF

Greenville

Thu 11/26

2:51 pm-7:04 pm

1 stop4h 13m

Buffalo

Thu 12/3

7:00 am-4:53 pm

2 stops9h 53m

$276

GreenvilleBuffalo

GSP Greenville - BUF Buffalo

GSPBUF

Greenville

Thu 11/26

2:51 pm-7:04 pm

1 stop4h 13m

Buffalo

Wed 12/2

7:00 am-4:53 pm

2 stops9h 53m

$276

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Fri 1/29

5:35 pm-9:45 pm

1 stop4h 10m

Buffalo

Mon 2/1

5:45 am-10:10 am

1 stop4h 25m

$281

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of February, then book flights to Buffalo from South Carolina during January instead. Flights to Buffalo in January, while not as cheap as those in February, still average around $322.

Can stopping save me money on South Carolina to Buffalo flights?

You could potentially save up to 46% on your flight if you consider stops on a South Carolina to Buffalo flight.

Cheap South Carolina to Buffalo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Buffalo

Best Price Found	$118
Fastest flight time	1h 44m
Direct flights	None

The best one-way flight to Buffalo from South Carolina in the past 72 hours is $118. The best round-trip flight deal from South Carolina to Buffalo found on momondo in the last 72 hours is $235.

The fastest flight from South Carolina to Buffalo takes 1h 44m

There are no direct flights from South Carolina to Buffalo. There are no popular flight routes from South Carolina to Buffalo.

Search flight deals

Frequently asked questions about flying from South Carolina to Buffalo

When did momondo last update prices for flights from South Carolina to Buffalo Airport?
Prices for flights from South Carolina to Buffalo Airport refresh daily.
How many operators does momondo search for flights from South Carolina to Buffalo Airport?
The number of operators available for flights from South Carolina to Buffalo Airport is 3 as of October 2026.
How old do you have to be to fly from South Carolina to Buffalo Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Buffalo Airport.
What documentation or ID do you need to fly to Buffalo Airport?
The necessary travel and health documents for your Buffalo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Buffalo

Compare and see reviews for airlines that fly from South Carolina to Buffalo with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $100	Free Cancellation	Rating 7.8 8,684 reviews	Search Delta flights
American Airlines	PriceFrom $200	Free Cancellation	Rating 7.0 12,204 reviews	Search American Airlines flights
Southwest	PriceFrom $236	Free Cancellation	Rating 7.9 4,220 reviews	Search Southwest flights

Batavia

Cheektowaga

Amherst

Williamsville

Tonawanda

Bowmansville

Lockport

Orchard Park

West Seneca

Grand Island

East Aurora

Angola

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Buffalo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to Buffalo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to Buffalo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Buffalo from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Buffalo?

Once you have performed a search for South Carolina to Buffalo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Buffalo right now. Can momondo alert me if prices change?

Price alerts on flights to Buffalo from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Buffalo trip

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Cheap flights from South Carolina to Buffalo from $118

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Buffalo departing on 11/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from South Carolina to Buffalo

Our best American Airlines deals on South Carolina to Buffalo flight tickets

Southwest flights from South Carolina to Buffalo

Our best Southwest deals on South Carolina to Buffalo flight tickets

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How to get the cheapest flight ticket from South Carolina to Buffalo

What is the cheapest month to fly to Buffalo?

Can stopping save me money on South Carolina to Buffalo flights?

What is the cheapest airline that flies from South Carolina to Buffalo?

What airlines fly to Buffalo?

How long does it take to fly to Buffalo?

Cheap South Carolina to Buffalo flight deals and tips

Best Price Found

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Frequently asked questions about flying from South Carolina to Buffalo

Best airlines flying from South Carolina to Buffalo

Compare and see reviews for airlines that fly from South Carolina to Buffalo with momondo

Traveling to a place near Buffalo?

Why use momondo?

An easier way to manage your Buffalo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

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Fly your favorite airline to Buffalo

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Buffalo

List of cabin classes available on flights landing in Buffalo. Availability may vary depending on flight origin and airline.

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