What airlines fly to Buffalo?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Buffalo from South Carolina according to our data. American Airlines is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Buffalo. Keep in mind that there are 6 different airlines that fly to Buffalo on a routine basis, so you have a few additional options to choose from.

How many flights depart from South Carolina to Buffalo on average per week?

As of September 2026, 8 flights take off from South Carolina and land in Buffalo each week. The most common flight departure day for this route is Mon, with 50% of weekly flights taking off on this day.

How long does it take to fly to Buffalo?

On average, it takes 3h 34m to fly from South Carolina to Buffalo if you fly out of Columbia (the most popular airport in South Carolina) and into Buffalo (the most popular airport in Buffalo). If you’re flying out of Myrtle Beach and into Buffalo, then the flight time is around 3h 35m.

What is the cheapest airline that flies from South Carolina to Buffalo?

Southwest, United Airlines, and American Airlines are the most popular carriers operating from South Carolina to Buffalo

When did momondo last update prices for flights from South Carolina to Buffalo Airport?

Prices for flights from South Carolina to Buffalo Airport refresh daily.

How many operators does momondo search for flights from South Carolina to Buffalo Airport?

The number of operators available for flights from South Carolina to Buffalo Airport is 5 as of September 2026.

How old do you have to be to fly from South Carolina to Buffalo Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Buffalo Airport.

What documentation or ID do you need to fly to Buffalo Airport?

The necessary travel and health documents for your Buffalo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$95 Cheap Flights from South Carolina to Buffalo in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Buffalo

Round-trip

One-way

Last minute

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Cheap round-trip flights

Enter your travel dates to find the best prices.

9:40 pm - 5:45 pmCLT Charlotte Douglas-BUF Buffalo

20h 05m1 stop Orlando

6:51 pm - 8:35 amBUF Buffalo-CLT Charlotte Douglas

13h 44m1 stop Orlando

$205Frontier

Wed, Sep 30 - Tue, Oct 6

9:32 am - 5:49 pmCLT Charlotte Douglas-BUF Buffalo

8h 17m1 stop Orlando

6:51 pm - 3:16 pmBUF Buffalo-CLT Charlotte Douglas

20h 25m1 stop Orlando

$210Frontier

Tue, Sep 22 - Tue, Sep 29

7:20 am - 2:26 pmCHS Charleston-BUF Buffalo

7h 06m1 stop Philadelphia

3:56 pm - 10:00 pmBUF Buffalo-CHS Charleston

6h 04m1 stop Charlotte Douglas

$261American Airlines

Wed, Sep 30 - Sat, Oct 10

6:02 pm - 10:33 pmCHS Charleston-BUF Buffalo

4h 31m1 stop New York LaGuardia

6:55 pm - 10:59 pmBUF Buffalo-CHS Charleston

4h 04m1 stop Charlotte Douglas

$261American Airlines

Wed, Nov 4 - Sat, Nov 7

8:05 pm - 11:45 pmCHS Charleston-BUF Buffalo

3h 40m1 stop Baltimore/Washington

9:45 am - 1:35 pmBUF Buffalo-CHS Charleston

3h 50m1 stop Baltimore/Washington

$261Southwest

Thu, Oct 22 - Tue, Oct 27

7:52 pm - 11:46 pmCHS Charleston-BUF Buffalo

3h 54m1 stop Washington, D.C. Dulles Intl

6:00 am - 10:06 amBUF Buffalo-CHS Charleston

4h 06m1 stop Washington, D.C. Dulles Intl

$261United Airlines

Mon, Nov 9 - Thu, Nov 12

6:40 am - 3:20 pmCHS Charleston-BUF Buffalo

8h 40m2 stops Nashville Intl Baltimore/Washington

12:55 pm - 5:10 pmBUF Buffalo-CHS Charleston

4h 15m1 stop Nashville Intl

$266Southwest

Wed, Oct 28 - Sat, Oct 31

3:29 pm - 11:46 pmCHS Charleston-BUF Buffalo

8h 17m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

6:00 am - 10:06 amBUF Buffalo-CHS Charleston

4h 06m1 stop Washington, D.C. Dulles Intl

$266United Airlines

Mon, Nov 9 - Thu, Nov 12

5:30 am - 11:16 amCHS Charleston-BUF Buffalo

5h 46m1 stop Atlanta Hartsfield-Jackson

5:20 pm - 11:59 pmBUF Buffalo-CHS Charleston

6h 39m1 stop Atlanta Hartsfield-Jackson

$271Delta

Tue, Oct 27 - Fri, Nov 6

5:34 pm - 11:59 pmCHS Charleston-BUF Buffalo

6h 25m1 stop Atlanta Hartsfield-Jackson

6:00 am - 12:52 pmBUF Buffalo-CHS Charleston

6h 52m1 stop Atlanta Hartsfield-Jackson

$281Delta

Mon, Nov 16 - Thu, Nov 19

Cheap last minute flights

Enter your travel dates to find the best prices.

9:40 pm - 5:45 pmCLT Charlotte Douglas-BUF Buffalo

20h 05m1 stop Orlando

12:49 pm - 6:21 pmBUF Buffalo-CLT Charlotte Douglas

5h 32m1 stop Orlando

$306Frontier

Sat, Sep 12 - Thu, Sep 17

9:32 am - 5:45 pmCLT Charlotte Douglas-BUF Buffalo

8h 13m1 stop Orlando

12:49 pm - 3:16 pmBUF Buffalo-CLT Charlotte Douglas

26h 27m1 stop Orlando

$310Frontier

Thu, Sep 10 - Sun, Sep 13

10:49 am - 4:22 pmCAE Columbia Metropolitan-BUF Buffalo

5h 33m1 stop Washington, D.C. Reagan-National

7:00 am - 2:03 pmBUF Buffalo-CAE Columbia Metropolitan

7h 03m1 stop New York LaGuardia

$357American Airlines

Sat, Sep 12 - Sat, Sep 19

7:05 am - 1:25 pmCAE Columbia Metropolitan-BUF Buffalo

6h 20m1 stop New York LaGuardia

6:59 pm - 11:49 pmBUF Buffalo-CAE Columbia Metropolitan

4h 50m1 stop Atlanta Hartsfield-Jackson

$373Delta

Wed, Sep 9 - Mon, Sep 21

10:05 am - 4:03 pmCAE Columbia Metropolitan-BUF Buffalo

5h 58m1 stop Atlanta Hartsfield-Jackson

6:59 pm - 11:49 pmBUF Buffalo-CAE Columbia Metropolitan

4h 50m1 stop Atlanta Hartsfield-Jackson

$373Delta

Sat, Sep 12 - Mon, Sep 21

10:22 am - 6:59 pmCAE Columbia Metropolitan-BUF Buffalo

8h 37m2 stops Washington, D.C. Dulles Intl Newark

7:00 am - 1:40 pmBUF Buffalo-CAE Columbia Metropolitan

6h 40m1 stop Chicago O'Hare Intl

$382United Airlines

Sat, Sep 12 - Sat, Sep 19

8:00 pm - 9:47 pmCLT Charlotte Douglas-BUF Buffalo

1h 47mnonstop

5:50 am - 7:50 amBUF Buffalo-CLT Charlotte Douglas

2h 00mnonstop

$383American Airlines

Sat, Sep 12 - Wed, Oct 14

8:25 am - 12:05 pmCLT Charlotte Douglas-BUF Buffalo

3h 40m1 stop Baltimore/Washington

12:35 pm - 5:25 pmBUF Buffalo-CLT Charlotte Douglas

4h 50m1 stop Baltimore/Washington

$399Southwest

Sat, Sep 12 - Wed, Oct 14

8:25 am - 4:45 pmCLT Charlotte Douglas-BUF Buffalo

8h 20m2 stops Baltimore/Washington Orlando

12:35 pm - 5:25 pmBUF Buffalo-CLT Charlotte Douglas

4h 50m1 stop Baltimore/Washington

$404Southwest

Sat, Sep 12 - Wed, Oct 14

2:15 pm - 11:44 pmCAE Columbia Metropolitan-BUF Buffalo

9h 29m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

7:00 am - 1:40 pmBUF Buffalo-CAE Columbia Metropolitan

6h 40m1 stop Chicago O'Hare Intl

$458United Airlines

Sat, Sep 12 - Tue, Sep 22

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Frontier flights from South Carolina to Buffalo

Our best Frontier deals on South Carolina to Buffalo flight tickets

Frontier

Sep 30

CLT9:40 pmCharlotte Douglas

20h 05m

1 stop

BUF5:45 pmBuffalo

Oct 6

BUF6:51 pmBuffalo

13h 44m

1 stop

CLT8:35 amCharlotte Douglas

$205

Frontier

Sep 22

CLT9:32 amCharlotte Douglas

8h 17m

1 stop

BUF5:49 pmBuffalo

Sep 29

BUF6:51 pmBuffalo

13h 44m

1 stop

CLT8:35 amCharlotte Douglas

$210

Frontier

Oct 13

CLT9:32 amCharlotte Douglas

8h 24m

1 stop

BUF5:56 pmBuffalo

Oct 20

BUF6:51 pmBuffalo

13h 46m

1 stop

CLT8:37 amCharlotte Douglas

$216

United Airlines flights from South Carolina to Buffalo

Our best United Airlines deals on South Carolina to Buffalo flight tickets

United Airlines

Oct 14

CHS7:53 pmCharleston

3h 57m

1 stop

BUF11:50 pmBuffalo

Oct 21

BUF3:05 pmBuffalo

8h 54m

2 stops

CHS11:59 pmCharleston

$266

United Airlines

Oct 30

CHS7:52 pmCharleston

3h 54m

1 stop

BUF11:46 pmBuffalo

Nov 1

BUF6:00 amBuffalo

7h 56m

2 stops

CHS1:56 pmCharleston

$286

United Airlines

Oct 28

CHS7:00 amCharleston

7h 20m

2 stops

BUF2:20 pmBuffalo

Oct 31

BUF6:00 amBuffalo

7h 56m

2 stops

CHS1:56 pmCharleston

$292

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteBuffalo

CLT Charlotte Douglas - BUF Buffalo

CLTBUF

Charlotte Douglas

Wed 9/30

9:40 pm-5:45 pm

1 stop20h 05m

Buffalo

Tue 10/6

6:51 pm-8:35 am

1 stop13h 44m

$205

CharlotteBuffalo

CLT Charlotte Douglas - BUF Buffalo

CLTBUF

Charlotte Douglas

Tue 9/22

9:32 am-5:49 pm

1 stop8h 17m

Buffalo

Tue 9/29

6:51 pm-3:16 pm

1 stop20h 25m

$210

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Wed 9/30

7:20 am-2:26 pm

1 stop7h 06m

Buffalo

Sat 10/10

3:56 pm-10:00 pm

1 stop6h 04m

$261

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Wed 11/4

6:02 pm-10:33 pm

1 stop4h 31m

Buffalo

Sat 11/7

6:55 pm-10:59 pm

1 stop4h 04m

$261

Quickest round-trip

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Thu 10/22

8:05 pm-11:45 pm

1 stop3h 40m

Buffalo

Tue 10/27

9:45 am-1:35 pm

1 stop3h 50m

$261

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Mon 11/9

7:52 pm-11:46 pm

1 stop3h 54m

Buffalo

Thu 11/12

6:00 am-10:06 am

1 stop4h 06m

$261

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Wed 10/28

6:40 am-3:20 pm

2 stops8h 40m

Buffalo

Sat 10/31

12:55 pm-5:10 pm

1 stop4h 15m

$266

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Mon 11/9

3:29 pm-11:46 pm

2 stops8h 17m

Buffalo

Thu 11/12

6:00 am-10:06 am

1 stop4h 06m

$266

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Tue 10/27

5:30 am-11:16 am

1 stop5h 46m

Buffalo

Fri 11/6

5:20 pm-11:59 pm

1 stop6h 39m

$271

CharlestonBuffalo

CHS Charleston - BUF Buffalo

CHSBUF

Charleston

Mon 11/16

5:34 pm-11:59 pm

1 stop6h 25m

Buffalo

Thu 11/19

6:00 am-12:52 pm

1 stop6h 52m

$281

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of February, then book flights to Buffalo from South Carolina during September instead. Flights to Buffalo in September, while not as cheap as those in February, still average around $318.

Can stopping save me money on South Carolina to Buffalo flights?

You could potentially save up to 51% on your flight if you consider stops on a South Carolina to Buffalo flight.

Cheap South Carolina to Buffalo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Buffalo

Best Price Found	$95
Fastest flight time	1h 44m
Direct flights	Every day
Airports in Buffalo	1 airport

The best one-way flight to Buffalo from South Carolina in the past 72 hours is $95. The best round-trip flight deal from South Carolina to Buffalo found on momondo in the last 72 hours is $205.

The fastest flight from South Carolina to Buffalo takes 1h 44m

Direct flights go from South Carolina to Buffalo every day.

There is 1 airport in Buffalo. From South Carolina there are direct flights to Buffalo (BUF).

Search flight deals

Frequently asked questions about flying from South Carolina to Buffalo

When did momondo last update prices for flights from South Carolina to Buffalo Airport?
Prices for flights from South Carolina to Buffalo Airport refresh daily.
How many operators does momondo search for flights from South Carolina to Buffalo Airport?
The number of operators available for flights from South Carolina to Buffalo Airport is 5 as of September 2026.
How old do you have to be to fly from South Carolina to Buffalo Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Buffalo Airport.
What documentation or ID do you need to fly to Buffalo Airport?
The necessary travel and health documents for your Buffalo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Buffalo

Compare and see reviews for airlines that fly from South Carolina to Buffalo with momondo

Airline	Rating	Free Cancellation	Price
JetBlue	PriceFrom $76	Free Cancellation	Rating 7.1 3,043 reviews	Search JetBlue flights
Delta	PriceFrom $128	Free Cancellation	Rating 7.8 8,550 reviews	Search Delta flights
American Airlines	PriceFrom $200	Free Cancellation	Rating 7.1 12,040 reviews	Search American Airlines flights
Southwest	PriceFrom $236	Free Cancellation	Rating 8.0 4,197 reviews	Search Southwest flights

Batavia

Cheektowaga

Amherst

Williamsville

Tonawanda

Bowmansville

Orchard Park

West Seneca

Grand Island

Lockport

East Aurora

Angola

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Buffalo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to Buffalo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to Buffalo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Buffalo from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Buffalo?

Once you have performed a search for South Carolina to Buffalo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Buffalo right now. Can momondo alert me if prices change?

Price alerts on flights to Buffalo from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from South Carolina to Buffalo from $95

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Buffalo departing on 9/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Frontier flights from South Carolina to Buffalo

Our best Frontier deals on South Carolina to Buffalo flight tickets

United Airlines flights from South Carolina to Buffalo

Our best United Airlines deals on South Carolina to Buffalo flight tickets

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How to get the cheapest flight ticket from South Carolina to Buffalo

What is the cheapest month to fly to Buffalo?

Can stopping save me money on South Carolina to Buffalo flights?

What is the cheapest airline that flies from South Carolina to Buffalo?

What airlines fly to Buffalo?

How many flights depart from South Carolina to Buffalo on average per week?

How long does it take to fly to Buffalo?

Cheap South Carolina to Buffalo flight deals and tips

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Airports in Buffalo

Frequently asked questions about flying from South Carolina to Buffalo

Best airlines flying from South Carolina to Buffalo

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Traveling to a place near Buffalo?

Why use momondo?

An easier way to manage your Buffalo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

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Airlines are sorted and displayed according to clicks in the past 7 days on momondo

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List of cabin classes available on flights landing in Buffalo. Availability may vary depending on flight origin and airline.

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