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Cheap flights from South Carolina to Buffalo from $76

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Buffalo departing on 5/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
7:58 pm - 6:46 pm
CLT
-
BUF
22h 48m
1 stop
Frontier Logo
8:49 pm - 12:05 pm
BUF
-
CLT
15h 16m
1 stop
$171Frontier
Do, Mai 7 - So, Mai 17
Frontier Logo
1:46 pm - 1:54 pm
CLT
-
BUF
24h 08m
2 stops
Frontier Logo
7:41 pm - 7:13 pm
BUF
-
CLT
23h 32m
1 stop
$173Frontier
Do, Mai 14 - Mo, Mai 18
Multiple Airlines Logo
7:58 pm - 6:46 pm
CLT
-
BUF
22h 48m
1 stop
Multiple Airlines Logo
11:36 am - 12:05 pm
BUF
-
CLT
24h 29m
2 stops
$174Multiple Airlines
Mi, Mai 13 - Di, Mai 19
Multiple Airlines Logo
7:30 am - 10:41 am
CLT
-
BUF
27h 11m
2 stops
Multiple Airlines Logo
7:52 pm - 12:05 pm
BUF
-
CLT
16h 13m
1 stop
$175Multiple Airlines
Mi, Mai 20 - Di, Mai 26
American Airlines Logo
6:57 pm - 11:19 pm
SAV
-
BUF
4h 22m
1 stop
American Airlines Logo
7:28 pm - 11:53 pm
BUF
-
SAV
4h 25m
1 stop
$251American Airlines
Fr, Mai 8 - Mo, Mai 11
American Airlines Logo
3:48 pm - 11:49 pm
SAV
-
BUF
8h 01m
2 stops
American Airlines Logo
1:45 pm - 5:41 pm
BUF
-
SAV
3h 56m
1 stop
$256American Airlines
Di, Mai 5 - Sa, Mai 9
Delta Logo
5:35 am - 11:11 am
CAE
-
BUF
5h 36m
1 stop
Delta Logo
6:00 am - 12:28 pm
BUF
-
CAE
6h 28m
1 stop
$261Delta
Mi, Aug 5 - Mi, Aug 12
United Airlines Logo
12:10 pm - 7:03 pm
SAV
-
BUF
6h 53m
1 stop
United Airlines Logo
7:00 pm - 11:52 pm
BUF
-
SAV
4h 52m
1 stop
$262United Airlines
Sa, Mai 23 - Mi, Mai 27
United Airlines Logo
3:14 pm - 9:03 pm
SAV
-
BUF
5h 49m
1 stop
United Airlines Logo
10:50 am - 5:25 pm
BUF
-
SAV
6h 35m
1 stop
$267United Airlines
Fr, Mai 22 - So, Mai 24
Delta Logo
7:39 pm - 11:59 pm
CAE
-
BUF
4h 20m
1 stop
Delta Logo
6:00 am - 12:28 pm
BUF
-
CAE
6h 28m
1 stop
$276Delta
So, Aug 2 - Mi, Aug 12

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American Airlines flights from South Carolina to Buffalo

Our best American Airlines deals on South Carolina to Buffalo flight tickets
American Airlines
May 8
SAV6:57 pmSavannah/Hilton Head
4h 22m
1 stop
BUF11:19 pmBuffalo
May 11
BUF7:28 pmBuffalo
4h 25m
1 stop
SAV11:53 pmSavannah/Hilton Head
$251
American Airlines
May 5
SAV3:48 pmSavannah/Hilton Head
8h 01m
2 stops
BUF11:49 pmBuffalo
May 9
BUF1:45 pmBuffalo
3h 56m
1 stop
SAV5:41 pmSavannah/Hilton Head
$256
American Airlines
May 29
CHS6:42 pmCharleston
5h 12m
1 stop
BUF11:54 pmBuffalo
Jun 3
BUF12:51 pmBuffalo
5h 11m
1 stop
CHS6:02 pmCharleston
$257

United Airlines flights from South Carolina to Buffalo

Our best United Airlines deals on South Carolina to Buffalo flight tickets
United Airlines
May 23
SAV12:10 pmSavannah/Hilton Head
6h 53m
1 stop
BUF7:03 pmBuffalo
May 27
BUF7:00 pmBuffalo
4h 52m
1 stop
SAV11:52 pmSavannah/Hilton Head
$262
United Airlines
May 22
SAV3:14 pmSavannah/Hilton Head
5h 49m
1 stop
BUF9:03 pmBuffalo
May 24
BUF10:50 amBuffalo
6h 35m
1 stop
SAV5:25 pmSavannah/Hilton Head
$267
United Airlines
May 27
CHS6:00 amCharleston
8h 25m
2 stops
BUF2:25 pmBuffalo
May 31
BUF6:09 amBuffalo
4h 07m
1 stop
CHS10:16 amCharleston
$271

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 18, 2026.
Use the filters below to find and compare flights from South Carolina to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Do 5/7

7:58 pm-6:46 pm

1 stop22h 48m

Buffalo

So 5/17

8:49 pm-12:05 pm

1 stop15h 16m

$171

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Do 5/14

1:46 pm-1:54 pm

2 stops24h 08m

Buffalo

Mo 5/18

7:41 pm-7:13 pm

1 stop23h 32m

$173

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Mi 5/13

7:58 pm-6:46 pm

1 stop22h 48m

Buffalo

Di 5/19

11:36 am-12:05 pm

2 stops24h 29m

$174

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Mi 5/20

7:30 am-10:41 am

2 stops27h 11m

Buffalo

Di 5/26

7:52 pm-12:05 pm

1 stop16h 13m

$175
Quickest round-trip

SavannahBuffalo

SAV - BUF

SAVBUF

Savannah/Hilton Head

Fr 5/8

6:57 pm-11:19 pm

1 stop4h 22m

Buffalo

Mo 5/11

7:28 pm-11:53 pm

1 stop4h 25m

$251

SavannahBuffalo

SAV - BUF

SAVBUF

Savannah/Hilton Head

Di 5/5

3:48 pm-11:49 pm

2 stops8h 01m

Buffalo

Sa 5/9

1:45 pm-5:41 pm

1 stop3h 56m

$256

ColumbiaBuffalo

CAE - BUF

CAEBUF

Columbia Metropolitan

Mi 8/5

5:35 am-11:11 am

1 stop5h 36m

Buffalo

Mi 8/12

6:00 am-12:28 pm

1 stop6h 28m

$261

SavannahBuffalo

SAV - BUF

SAVBUF

Savannah/Hilton Head

Sa 5/23

12:10 pm-7:03 pm

1 stop6h 53m

Buffalo

Mi 5/27

7:00 pm-11:52 pm

1 stop4h 52m

$262

SavannahBuffalo

SAV - BUF

SAVBUF

Savannah/Hilton Head

Fr 5/22

3:14 pm-9:03 pm

1 stop5h 49m

Buffalo

So 5/24

10:50 am-5:25 pm

1 stop6h 35m

$267

ColumbiaBuffalo

CAE - BUF

CAEBUF

Columbia Metropolitan

So 8/2

7:39 pm-11:59 pm

1 stop4h 20m

Buffalo

Mi 8/12

6:00 am-12:28 pm

1 stop6h 28m

$276

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Buffalo from

How to get the cheapest flight ticket from South Carolina to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of November, then book flights to Buffalo from South Carolina during October instead. Flights to Buffalo in October, while not as cheap as those in November, still average around $226.

How far in advance should I book a flight to Buffalo?

You are more likely to see cheaper flights to Buffalo from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Buffalo for around $293 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Buffalo from South Carolina for as low as $199 on momondo.

Can stopping save me money on South Carolina to Buffalo flights?

You could potentially save up to 44% on your flight if you consider stops on a South Carolina to Buffalo flight.

Cheap South Carolina to Buffalo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Buffalo

Fastest flight time

1h 46m

Direct flights

Every day

Airports in Buffalo

1 airport
The fastest flight from South Carolina to Buffalo takes 1h 46m
Direct flights go from South Carolina to Buffalo every day.
There is 1 airport in Buffalo. From South Carolina there are direct flights to Buffalo (BUF).
Search flight deals

Frequently asked questions about flying from South Carolina to Buffalo

  • When did momondo last update prices for flights from South Carolina to Buffalo Airport?

    Prices for flights from South Carolina to Buffalo Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Buffalo Airport?

  • How old do you have to be to fly from South Carolina to Buffalo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The necessary travel and health documents for your Buffalo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Buffalo

Compare and see reviews for airlines that fly from South Carolina to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $80Free CancellationRating
7.2
2,945 reviews
Search JetBlue flights
DeltaPriceFrom $118Free CancellationRating
7.9
8,424 reviews
Search Delta flights
American AirlinesPriceFrom $195Free CancellationRating
7.1
11,605 reviews
Search American Airlines flights
SouthwestPriceFrom $236Free CancellationRating
8.0
4,330 reviews
Search Southwest flights
United AirlinesPriceFrom $248Free CancellationRating
7.4
9,603 reviews
Search United Airlines flights

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Tonawanda
Grand Island
Orchard Park
Williamsville
Lockport
West Seneca
Bowmansville
East Aurora
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Buffalo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to Buffalo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to Buffalo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Buffalo from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Buffalo?

Once you have performed a search for South Carolina to Buffalo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Buffalo right now. Can momondo alert me if prices change?

Price alerts on flights to Buffalo from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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