What airlines fly to Buffalo?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Buffalo from South Carolina according to our data. American Airlines is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Buffalo. Keep in mind that there are 6 different airlines that fly to Buffalo on a routine basis, so you have a few additional options to choose from.

How many flights depart from South Carolina to Buffalo on average per week?

As of July 2026, 20 flights take off from South Carolina and land in Buffalo each week. The most common flight departure day for this route is Sun, with 20% of weekly flights taking off on this day.

How long does it take to fly to Buffalo?

On average, it takes 3h 51m to fly from South Carolina to Buffalo if you fly out of Myrtle Beach (the most popular airport in South Carolina) and into Buffalo (the most popular airport in Buffalo). If you’re flying out of Charleston and into Buffalo, then the flight time is around 3h 53m.

What is the cheapest airline that flies from South Carolina to Buffalo?

Frontier, Delta, and Southwest are the most popular carriers operating from South Carolina to Buffalo

When did momondo last update prices for flights from South Carolina to Buffalo Airport?

Prices for flights from South Carolina to Buffalo Airport refresh daily.

How many operators does momondo search for flights from South Carolina to Buffalo Airport?

The number of operators available for flights from South Carolina to Buffalo Airport is 5 as of July 2026.

How old do you have to be to fly from South Carolina to Buffalo Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Buffalo Airport.

What documentation or ID do you need to fly to Buffalo Airport?

The necessary travel and health documents for your Buffalo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$104 Cheap Flights from South Carolina to Buffalo in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Buffalo

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

12:24 pm - 7:06 pm

CLT

BUF

6h 42m

1 stop

9:29 pm - 8:01 am

BUF

CLT

10h 32m

1 stop

$210Frontier

Tue, Aug 11 - Tue, Aug 18

9:52 pm - 9:23 am

CLT

BUF

11h 31m

1 stop

9:29 pm - 8:01 am

BUF

CLT

10h 32m

1 stop

$220Frontier

Wed, Aug 26 - Tue, Sep 1

5:10 am - 11:08 am

CHS

BUF

5h 58m

1 stop

6:01 am - 10:42 am

BUF

CHS

4h 41m

1 stop

$239Delta

Mon, Aug 17 - Mon, Aug 24

1:25 pm - 5:45 pm

CHS

BUF

4h 20m

1 stop

6:30 am - 3:25 pm

BUF

CHS

8h 55m

2 stops

$244Southwest

Wed, Aug 26 - Mon, Aug 31

7:35 am - 2:20 pm

CHS

BUF

6h 45m

2 stops

6:30 am - 3:25 pm

BUF

CHS

8h 55m

2 stops

$249Southwest

Wed, Aug 26 - Mon, Aug 31

11:40 am - 4:56 pm

CHS

BUF

5h 16m

1 stop

6:12 am - 10:03 am

BUF

CHS

3h 51m

1 stop

$253United Airlines

Sat, Aug 22 - Sat, Sep 5

2:20 pm - 7:01 pm

SAV

BUF

4h 41m

1 stop

3:10 pm - 11:57 pm

BUF

SAV

8h 47m

1 stop

$255JetBlue

Thu, Oct 15 - Tue, Oct 20

11:05 am - 7:01 pm

CHS

BUF

7h 56m

1 stop

12:10 pm - 7:30 pm

BUF

CHS

7h 20m

1 stop

$262JetBlue

Wed, Oct 14 - Fri, Oct 16

7:51 pm - 11:44 pm

CHS

BUF

3h 53m

1 stop

6:55 am - 1:58 pm

BUF

CHS

7h 03m

1 stop

$269United Airlines

Thu, Sep 10 - Sun, Sep 13

7:47 pm - 11:59 pm

CAE

BUF

4h 12m

1 stop

6:10 pm - 11:17 pm

BUF

CAE

5h 07m

1 stop

$285Delta

Thu, Aug 13 - Wed, Aug 19

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Delta flights from South Carolina to Buffalo

Our best Delta deals on South Carolina to Buffalo flight tickets

Delta

Aug 17

CHS5:10 amCharleston

5h 58m

1 stop

BUF11:08 amBuffalo

Aug 24

BUF6:01 amBuffalo

4h 41m

1 stop

CHS10:42 amCharleston

$239

Delta

Sep 4

CHS5:06 pmCharleston

6h 53m

1 stop

BUF11:59 pmBuffalo

Sep 6

BUF6:05 amBuffalo

5h 49m

1 stop

CHS11:54 amCharleston

$277

Delta

Aug 13

CAE7:47 pmColumbia Metropolitan

4h 12m

1 stop

BUF11:59 pmBuffalo

Aug 19

BUF6:10 pmBuffalo

5h 07m

1 stop

CAE11:17 pmColumbia Metropolitan

$285

Southwest flights from South Carolina to Buffalo

Our best Southwest deals on South Carolina to Buffalo flight tickets

Southwest

Aug 26

CHS1:25 pmCharleston

4h 20m

1 stop

BUF5:45 pmBuffalo

Aug 31

BUF6:30 amBuffalo

8h 55m

2 stops

CHS3:25 pmCharleston

$244

Southwest

Aug 26

CHS7:35 amCharleston

6h 45m

2 stops

BUF2:20 pmBuffalo

Aug 31

BUF6:30 amBuffalo

8h 55m

2 stops

CHS3:25 pmCharleston

$249

Southwest

Aug 26

CHS8:10 amCharleston

4h 20m

1 stop

BUF12:30 pmBuffalo

Aug 31

BUF12:30 pmBuffalo

6h 40m

1 stop

CHS7:10 pmCharleston

$251

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Tue 8/11

12:24 pm-7:06 pm

1 stop6h 42m

Buffalo

Tue 8/18

9:29 pm-8:01 am

1 stop10h 32m

$210

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Wed 8/26

9:52 pm-9:23 am

1 stop11h 31m

Buffalo

Tue 9/1

9:29 pm-8:01 am

1 stop10h 32m

$220

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Mon 8/17

5:10 am-11:08 am

1 stop5h 58m

Buffalo

Mon 8/24

6:01 am-10:42 am

1 stop4h 41m

$239

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Wed 8/26

1:25 pm-5:45 pm

1 stop4h 20m

Buffalo

Mon 8/31

6:30 am-3:25 pm

2 stops8h 55m

$244

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Wed 8/26

7:35 am-2:20 pm

2 stops6h 45m

Buffalo

Mon 8/31

6:30 am-3:25 pm

2 stops8h 55m

$249

Quickest round-trip

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Sat 8/22

11:40 am-4:56 pm

1 stop5h 16m

Buffalo

Sat 9/5

6:12 am-10:03 am

1 stop3h 51m

$253

SavannahBuffalo

SAV - BUF

SAVBUF

Savannah/Hilton Head

Thu 10/15

2:20 pm-7:01 pm

1 stop4h 41m

Buffalo

Tue 10/20

3:10 pm-11:57 pm

1 stop8h 47m

$255

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Wed 10/14

11:05 am-7:01 pm

1 stop7h 56m

Buffalo

Fri 10/16

12:10 pm-7:30 pm

1 stop7h 20m

$262

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Thu 9/10

7:51 pm-11:44 pm

1 stop3h 53m

Buffalo

Sun 9/13

6:55 am-1:58 pm

1 stop7h 03m

$269

ColumbiaBuffalo

CAE - BUF

CAEBUF

Columbia Metropolitan

Thu 8/13

7:47 pm-11:59 pm

1 stop4h 12m

Buffalo

Wed 8/19

6:10 pm-11:17 pm

1 stop5h 07m

$285

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of February, then book flights to Buffalo from South Carolina during November instead. Flights to Buffalo in November, while not as cheap as those in February, still average around $323.

Can stopping save me money on South Carolina to Buffalo flights?

You could potentially save up to 42% on your flight if you consider stops on a South Carolina to Buffalo flight.

Cheap South Carolina to Buffalo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Buffalo

Fastest flight time	1h 45m
Direct flights	Every day
Airports in Buffalo	1 airport

The fastest flight from South Carolina to Buffalo takes 1h 45m

Direct flights go from South Carolina to Buffalo every day.

There is 1 airport in Buffalo. From South Carolina there are direct flights to Buffalo (BUF).

Search flight deals

Frequently asked questions about flying from South Carolina to Buffalo

When did momondo last update prices for flights from South Carolina to Buffalo Airport?
Prices for flights from South Carolina to Buffalo Airport refresh daily.
How many operators does momondo search for flights from South Carolina to Buffalo Airport?
The number of operators available for flights from South Carolina to Buffalo Airport is 5 as of July 2026.
How old do you have to be to fly from South Carolina to Buffalo Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Buffalo Airport.
What documentation or ID do you need to fly to Buffalo Airport?
The necessary travel and health documents for your Buffalo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Buffalo

Compare and see reviews for airlines that fly from South Carolina to Buffalo with momondo

Airline	Rating	Free Cancellation	Price
JetBlue	PriceFrom $76	Free Cancellation	Rating 7.1 3,009 reviews	Search JetBlue flights
Delta	PriceFrom $128	Free Cancellation	Rating 7.8 8,481 reviews	Search Delta flights
American Airlines	PriceFrom $195	Free Cancellation	Rating 7.1 11,822 reviews	Search American Airlines flights
Southwest	PriceFrom $236	Free Cancellation	Rating 8.0 4,242 reviews	Search Southwest flights

Batavia

Cheektowaga

Amherst

Tonawanda

Williamsville

Orchard Park

Grand Island

Bowmansville

West Seneca

Lockport

East Aurora

Eden

Angola

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Buffalo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to Buffalo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to Buffalo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Buffalo from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Buffalo?

Once you have performed a search for South Carolina to Buffalo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Buffalo right now. Can momondo alert me if prices change?

Price alerts on flights to Buffalo from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from South Carolina to Buffalo from $104

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Buffalo departing on 8/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from South Carolina to Buffalo

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What is the cheapest airline that flies from South Carolina to Buffalo?

What airlines fly to Buffalo?

How many flights depart from South Carolina to Buffalo on average per week?

How long does it take to fly to Buffalo?

Cheap South Carolina to Buffalo flight deals and tips

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Frequently asked questions about flying from South Carolina to Buffalo

Best airlines flying from South Carolina to Buffalo

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Why use momondo?

An easier way to manage your Buffalo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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