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Cheap flights from Sioux City to Knoxville from $324

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux City to Knoxville departing on 1/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
1:00 pm - 9:10 pmSUX-TYS
7h 10m1 stop
United Airlines Logo
4:55 pm - 9:45 amTYS-SUX
17h 50m2 stops
$488United Airlines
Find Deal
Tue, Mar 3 - Sat, Mar 7
United Airlines Logo
1:00 pm - 9:10 pmSUX-TYS
7h 10m1 stop
United Airlines Logo
6:55 pm - 4:41 pmTYS-SUX
22h 46m1 stop
$492United Airlines
Find Deal
Tue, Mar 3 - Sat, Mar 7
United Airlines Logo
6:00 am - 7:55 pmSUX-TYS
12h 55m2 stops
United Airlines Logo
4:55 pm - 9:45 amTYS-SUX
17h 50m2 stops
$493United Airlines
Find Deal
Tue, Mar 3 - Sat, Mar 7
United Airlines Logo
1:00 pm - 9:10 pmSUX-TYS
7h 10m1 stop
United Airlines Logo
7:25 pm - 9:39 amTYS-SUX
15h 14m2 stops
$528United Airlines
Find Deal
Tue, Mar 3 - Sat, Mar 7
United Airlines Logo
6:00 am - 6:10 pmSUX-TYS
11h 10m2 stops
United Airlines Logo
7:25 pm - 9:39 amTYS-SUX
15h 14m2 stops
$577United Airlines
Find Deal
Tue, Mar 3 - Sat, Mar 7
United Airlines Logo
6:46 pm - 3:51 pmSUX-TYS
20h 05m1 stop
United Airlines Logo
5:54 pm - 10:59 pmTYS-SUX
6h 05m1 stop
$897United Airlines
Find Deal
Sun, Nov 30 - Thu, Dec 4
United Airlines Logo
6:46 pm - 11:59 pmSUX-TYS
28h 13m2 stops
United Airlines Logo
5:54 pm - 10:59 pmTYS-SUX
6h 05m1 stop
$907United Airlines
Find Deal
Sun, Nov 30 - Thu, Dec 4
United Airlines Logo
6:46 pm - 11:44 pmSUX-TYS
27h 58m2 stops
United Airlines Logo
9:10 am - 6:10 pmTYS-SUX
10h 00m2 stops
$912United Airlines
Find Deal
Sun, Nov 30 - Thu, Dec 4
United Airlines Logo
6:00 am - 3:05 pmSUX-TYS
8h 05m1 stop
United Airlines Logo
4:25 pm - 11:34 pmTYS-SUX
8h 09m1 stop
$1,000United Airlines
Find Deal
Tue, Mar 3 - Sat, Mar 7

United Airlines flights from Sioux City to Knoxville

Our best United Airlines deals on Sioux City to Knoxville flight tickets
United Airlines
Mar 3
SUX1:00 pmSioux City Sioux Gateway
7h 10m
1 stop
TYS9:10 pmKnoxville McGhee Tyson
Mar 7
TYS4:55 pmKnoxville McGhee Tyson
17h 50m
2 stops
SUX9:45 amSioux City Sioux Gateway
$488
Find similar
United Airlines
Mar 3
SUX1:00 pmSioux City Sioux Gateway
7h 10m
1 stop
TYS9:10 pmKnoxville McGhee Tyson
Mar 7
TYS6:55 pmKnoxville McGhee Tyson
22h 46m
1 stop
SUX4:41 pmSioux City Sioux Gateway
$492
Find similar
United Airlines
Mar 3
SUX6:00 amSioux City Sioux Gateway
12h 55m
2 stops
TYS7:55 pmKnoxville McGhee Tyson
Mar 7
TYS4:55 pmKnoxville McGhee Tyson
17h 50m
2 stops
SUX9:45 amSioux City Sioux Gateway
$493
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Sioux City to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 16, 2025.
Use the filters below to find and compare flights from Sioux City to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux CityKnoxville

SUX - TYS

SUXTYS

Sioux City Sioux Gateway

Tue 3/3

1:00 pm-9:10 pm

1 stop7h 10m

Knoxville McGhee Tyson

Sat 3/7

4:55 pm-9:45 am

2 stops17h 50m

$488

Sioux CityKnoxville

SUX - TYS

SUXTYS

Sioux City Sioux Gateway

Tue 3/3

1:00 pm-9:10 pm

1 stop7h 10m

Knoxville McGhee Tyson

Sat 3/7

6:55 pm-4:41 pm

1 stop22h 46m

$492

Sioux CityKnoxville

SUX - TYS

SUXTYS

Sioux City Sioux Gateway

Tue 3/3

6:00 am-7:55 pm

2 stops12h 55m

Knoxville McGhee Tyson

Sat 3/7

4:55 pm-9:45 am

2 stops17h 50m

$493

Sioux CityKnoxville

SUX - TYS

SUXTYS

Sioux City Sioux Gateway

Tue 3/3

1:00 pm-9:10 pm

1 stop7h 10m

Knoxville McGhee Tyson

Sat 3/7

7:25 pm-9:39 am

2 stops15h 14m

$528

Sioux CityKnoxville

SUX - TYS

SUXTYS

Sioux City Sioux Gateway

Tue 3/3

6:00 am-6:10 pm

2 stops11h 10m

Knoxville McGhee Tyson

Sat 3/7

7:25 pm-9:39 am

2 stops15h 14m

$577

Sioux CityKnoxville

SUX - TYS

SUXTYS

Sioux City Sioux Gateway

Sun 11/30

6:46 pm-3:51 pm

1 stop20h 05m

Knoxville McGhee Tyson

Thu 12/4

5:54 pm-10:59 pm

1 stop6h 05m

$897

Sioux CityKnoxville

SUX - TYS

SUXTYS

Sioux City Sioux Gateway

Sun 11/30

6:46 pm-11:59 pm

2 stops28h 13m

Knoxville McGhee Tyson

Thu 12/4

5:54 pm-10:59 pm

1 stop6h 05m

$907

Sioux CityKnoxville

SUX - TYS

SUXTYS

Sioux City Sioux Gateway

Sun 11/30

6:46 pm-11:44 pm

2 stops27h 58m

Knoxville McGhee Tyson

Thu 12/4

9:10 am-6:10 pm

2 stops10h 00m

$912

Sioux CityKnoxville

SUX - TYS

SUXTYS

Sioux City Sioux Gateway

Tue 3/3

6:00 am-3:05 pm

1 stop8h 05m

Knoxville McGhee Tyson

Sat 3/7

4:25 pm-11:34 pm

1 stop8h 09m

$1,000

Sioux CityKnoxville

SUX - TYS

SUXTYS

Sioux City Sioux Gateway

Sun 1/25

12:45 pm-4:53 pm

1 stop27h 08m

$324

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Sioux City to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Sioux City Sioux Gateway to Knoxville McGhee Tyson?

United Airlines is the most popular carrier operating from Sioux City Sioux Gateway to Knoxville McGhee Tyson

What airlines fly to Knoxville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from Sioux City according to our data. American Airlines is the first choice among our users, with 57% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

When to book flights from Sioux City to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux City to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Sioux City to Knoxville (SUX to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux City to Knoxville

Direct flights

None
There are no direct flights from Sioux City to Knoxville. There are no popular flight routes from Sioux City to Knoxville.
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  • How far is Sioux City Sioux Gateway to Knoxville McGhee Tyson by plane?

    The straight-line distance from Sioux City Sioux Gateway to Knoxville McGhee Tyson is 804.5 mi. 7h 10m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Sioux City Sioux Gateway Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Sioux City Sioux Gateway Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How old do you have to be to fly from Sioux City Sioux Gateway Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Sioux City Sioux Gateway Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Sioux City to Knoxville?

Finding the right flight to Knoxville from Sioux City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Sioux City to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Sioux City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Sioux City to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Sioux City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Sioux City to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Sioux City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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