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Cheap flights from Santa Fe to Greenville from $259

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Fe to Greenville departing on 8/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Fe to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:54 pm - 10:45 pm
SAF
-
GSP
7h 51m
1 stop
American Airlines Logo
6:01 am - 12:24 pm
GSP
-
SAF
8h 23m
1 stop
$583American Airlines
Wed, Apr 1 - Sun, Apr 5
American Airlines Logo
2:35 pm - 11:42 pm
SAF
-
GSP
7h 07m
1 stop
American Airlines Logo
6:01 am - 12:24 pm
GSP
-
SAF
8h 23m
1 stop
$603American Airlines
Thu, Apr 2 - Sun, Apr 5
American Airlines Logo
12:54 pm - 10:45 pm
SAF
-
GSP
7h 51m
1 stop
American Airlines Logo
6:01 am - 12:24 pm
GSP
-
SAF
8h 23m
1 stop
$628American Airlines
Fri, Mar 27 - Tue, Mar 31
American Airlines Logo
12:54 pm - 10:45 pm
SAF
-
GSP
7h 51m
1 stop
American Airlines Logo
7:40 am - 2:04 pm
GSP
-
SAF
8h 24m
1 stop
$633American Airlines
Wed, Apr 1 - Sat, Apr 4
American Airlines Logo
6:42 pm - 8:38 am
SAF
-
GSP
11h 56m
2 stops
American Airlines Logo
6:01 am - 12:24 pm
GSP
-
SAF
8h 23m
1 stop
$638American Airlines
Fri, Mar 27 - Tue, Mar 31
American Airlines Logo
2:35 pm - 11:42 pm
SAF
-
GSP
7h 07m
1 stop
American Airlines Logo
7:40 am - 2:04 pm
GSP
-
SAF
8h 24m
1 stop
$653American Airlines
Thu, Apr 2 - Sat, Apr 4
American Airlines Logo
2:35 pm - 11:42 pm
SAF
-
GSP
7h 07m
1 stop
American Airlines Logo
6:01 am - 3:05 pm
GSP
-
SAF
11h 04m
2 stops
$658American Airlines
Thu, Apr 2 - Sun, Apr 5
American Airlines Logo
12:54 pm - 10:45 pm
SAF
-
GSP
7h 51m
1 stop
American Airlines Logo
6:01 am - 2:45 pm
GSP
-
SAF
10h 44m
2 stops
$712American Airlines
Wed, Apr 1 - Sat, Apr 4
American Airlines Logo
6:42 pm - 8:38 am
SAF
-
GSP
11h 56m
2 stops
American Airlines Logo
5:20 am - 3:45 pm
GSP
-
SAF
12h 25m
2 stops
$720American Airlines
Fri, Mar 27 - Tue, Mar 31
American Airlines Logo
10:09 am - 9:48 pm
SAF
-
GSP
9h 39m
2 stops
American Airlines Logo
6:01 am - 12:24 pm
GSP
-
SAF
8h 23m
1 stop
$722American Airlines
Fri, Apr 3 - Sun, Apr 5

American Airlines flights from Santa Fe to Greenville

Our best American Airlines deals on Santa Fe to Greenville flight tickets
American Airlines
Apr 1
SAF12:54 pmSanta Fe
7h 51m
1 stop
GSP10:45 pmGreenville
Apr 5
GSP6:01 amGreenville
8h 23m
1 stop
SAF12:24 pmSanta Fe
$583
American Airlines
Apr 2
SAF2:35 pmSanta Fe
7h 07m
1 stop
GSP11:42 pmGreenville
Apr 5
GSP6:01 amGreenville
8h 23m
1 stop
SAF12:24 pmSanta Fe
$603
American Airlines
Mar 27
SAF12:54 pmSanta Fe
7h 51m
1 stop
GSP10:45 pmGreenville
Mar 31
GSP6:01 amGreenville
8h 23m
1 stop
SAF12:24 pmSanta Fe
$628

United Airlines flights from Santa Fe to Greenville

Our best United Airlines deals on Santa Fe to Greenville flight tickets
United Airlines
Mar 16
SAF7:00 amSanta Fe
14h 59m
2 stops
GSP11:59 pmGreenville
Mar 20
GSP4:55 pmGreenville
23h 50m
2 stops
SAF2:45 pmSanta Fe
$688
United Airlines
Mar 16
SAF7:00 amSanta Fe
14h 59m
2 stops
GSP11:59 pmGreenville
Mar 20
GSP4:13 pmGreenville
18h 55m
1 stop
SAF9:08 amSanta Fe
$713
United Airlines
Apr 2
SAF3:24 pmSanta Fe
16h 31m
2 stops
GSP9:55 amGreenville
Apr 4
GSP4:41 pmGreenville
18h 28m
2 stops
SAF9:09 amSanta Fe
$773

momondo Fare Finder

 
Customize your flight search to find flights from Santa Fe to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Santa Fe to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Wed 4/1

12:54 pm-10:45 pm

1 stop7h 51m

Greenville

Sun 4/5

6:01 am-12:24 pm

1 stop8h 23m

$583
Quickest round-trip

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Thu 4/2

2:35 pm-11:42 pm

1 stop7h 07m

Greenville

Sun 4/5

6:01 am-12:24 pm

1 stop8h 23m

$603

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Fri 3/27

12:54 pm-10:45 pm

1 stop7h 51m

Greenville

Tue 3/31

6:01 am-12:24 pm

1 stop8h 23m

$628

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Wed 4/1

12:54 pm-10:45 pm

1 stop7h 51m

Greenville

Sat 4/4

7:40 am-2:04 pm

1 stop8h 24m

$633

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Fri 3/27

6:42 pm-8:38 am

2 stops11h 56m

Greenville

Tue 3/31

6:01 am-12:24 pm

1 stop8h 23m

$638

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Thu 4/2

2:35 pm-11:42 pm

1 stop7h 07m

Greenville

Sat 4/4

7:40 am-2:04 pm

1 stop8h 24m

$653

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Thu 4/2

2:35 pm-11:42 pm

1 stop7h 07m

Greenville

Sun 4/5

6:01 am-3:05 pm

2 stops11h 04m

$658

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Wed 4/1

12:54 pm-10:45 pm

1 stop7h 51m

Greenville

Sat 4/4

6:01 am-2:45 pm

2 stops10h 44m

$712

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Fri 3/27

6:42 pm-8:38 am

2 stops11h 56m

Greenville

Tue 3/31

5:20 am-3:45 pm

2 stops12h 25m

$720

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Fri 4/3

10:09 am-9:48 pm

2 stops9h 39m

Greenville

Sun 4/5

6:01 am-12:24 pm

1 stop8h 23m

$722

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Santa Fe to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santa Fe to Greenville?

United Airlines is the most popular carrier operating from Santa Fe to Greenville

What airlines fly to Greenville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Greenville from Santa Fe according to our data. American Airlines is the first choice among our users, with 51% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 3 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

When to book flights from Santa Fe to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Fe to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Fe to Greenville (SAF to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Fe to Greenville

Fastest flight time

27h 31m

Direct flights

None
The fastest flight from Santa Fe to Greenville takes 27h 31m
There are no direct flights from Santa Fe to Greenville. There are no popular flight routes from Santa Fe to Greenville.
Search flight deals

  • How far is Santa Fe to Greenville by plane?

    Santa Fe and Greenville are 1325.3 mi apart from one another. Typically, this will take 27h 31m by plane in normal conditions.

  • When did momondo last update prices for flights from Santa Fe Airport to Greenville Airport?

    Prices for flights from Santa Fe Airport to Greenville Airport refresh daily.

  • How old do you have to be to fly from Santa Fe Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Fe Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Santa Fe to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santa Fe to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santa Fe to Greenville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Greenville from Santa Fe with this policy.

How can momondo help me find flights from Santa Fe to Greenville?

Once all potential Santa Fe to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Fe to Greenville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Greenville from Santa Fe. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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