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Cheap flights from Santa Fe to Greenville from $354

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Fe to Greenville departing on 9/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santa Fe to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:38 pm - 10:17 pm
SAF
-
GSP
7h 39m
1 stop
American Airlines Logo
5:28 pm - 9:58 pm
GSP
-
SAF
6h 30m
1 stop
$354American Airlines
Wed, Sep 2 - Tue, Sep 8
American Airlines Logo
10:11 am - 9:50 pm
SAF
-
GSP
9h 39m
2 stops
American Airlines Logo
5:28 pm - 9:58 pm
GSP
-
SAF
6h 30m
1 stop
$364American Airlines
Wed, Sep 2 - Tue, Sep 8
United Airlines Logo
7:00 am - 11:19 pm
SAF
-
GSP
14h 19m
2 stops
United Airlines Logo
4:15 pm - 10:01 pm
GSP
-
SAF
7h 46m
1 stop
$434United Airlines
Wed, Jan 6 - Sat, Jan 9
United Airlines Logo
10:45 am - 11:19 pm
SAF
-
GSP
10h 34m
2 stops
United Airlines Logo
2:54 pm - 10:01 pm
GSP
-
SAF
9h 07m
2 stops
$439United Airlines
Wed, Jan 6 - Sat, Jan 9
American Airlines Logo
2:08 pm - 10:17 pm
SAF
-
GSP
6h 09m
1 stop
American Airlines Logo
5:28 pm - 9:58 pm
GSP
-
SAF
6h 30m
1 stop
$459American Airlines
Thu, Aug 13 - Sun, Aug 16
American Airlines Logo
8:40 am - 8:46 pm
SAF
-
GSP
10h 06m
2 stops
American Airlines Logo
5:28 pm - 9:58 pm
GSP
-
SAF
6h 30m
1 stop
$469American Airlines
Thu, Aug 13 - Sun, Aug 16
American Airlines Logo
2:08 pm - 10:17 pm
SAF
-
GSP
6h 09m
1 stop
American Airlines Logo
5:28 pm - 9:58 pm
GSP
-
SAF
6h 30m
1 stop
$474American Airlines
Thu, Aug 13 - Sun, Aug 16
American Airlines Logo
10:11 am - 9:50 pm
SAF
-
GSP
9h 39m
2 stops
American Airlines Logo
7:00 am - 11:58 am
GSP
-
SAF
6h 58m
1 stop
$484American Airlines
Thu, Aug 13 - Sun, Aug 16
American Airlines Logo
8:40 am - 9:50 pm
SAF
-
GSP
11h 10m
2 stops
American Airlines Logo
5:30 am - 1:38 pm
GSP
-
SAF
10h 08m
2 stops
$489American Airlines
Thu, Aug 13 - Sun, Aug 16
United Airlines Logo
7:00 am - 3:10 pm
SAF
-
GSP
6h 10m
1 stop
United Airlines Logo
4:15 pm - 10:01 pm
GSP
-
SAF
7h 46m
1 stop
$504United Airlines
Wed, Jan 6 - Sat, Jan 9

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United Airlines flights from Santa Fe to Greenville

Our best United Airlines deals on Santa Fe to Greenville flight tickets
United Airlines
Jan 6
SAF7:00 amSanta Fe
14h 19m
2 stops
GSP11:19 pmGreenville
Jan 9
GSP4:15 pmGreenville
7h 46m
1 stop
SAF10:01 pmSanta Fe
$434
United Airlines
Jan 6
SAF10:45 amSanta Fe
10h 34m
2 stops
GSP11:19 pmGreenville
Jan 9
GSP2:54 pmGreenville
9h 07m
2 stops
SAF10:01 pmSanta Fe
$439
United Airlines
Jan 6
SAF7:00 amSanta Fe
6h 10m
1 stop
GSP3:10 pmGreenville
Jan 9
GSP4:15 pmGreenville
7h 46m
1 stop
SAF10:01 pmSanta Fe
$504

American Airlines flights from Santa Fe to Greenville

Our best American Airlines deals on Santa Fe to Greenville flight tickets
American Airlines
Sep 2
SAF12:38 pmSanta Fe
7h 39m
1 stop
GSP10:17 pmGreenville
Sep 8
GSP5:28 pmGreenville
6h 30m
1 stop
SAF9:58 pmSanta Fe
$354
American Airlines
Sep 2
SAF10:11 amSanta Fe
9h 39m
2 stops
GSP9:50 pmGreenville
Sep 8
GSP5:28 pmGreenville
6h 30m
1 stop
SAF9:58 pmSanta Fe
$364
American Airlines
Aug 13
SAF2:08 pmSanta Fe
6h 09m
1 stop
GSP10:17 pmGreenville
Aug 16
GSP5:28 pmGreenville
6h 30m
1 stop
SAF9:58 pmSanta Fe
$459

momondo Fare Finder

 
Customize your flight search to find flights from Santa Fe to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 3, 2026.
Use the filters below to find and compare flights from Santa Fe to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Wed 9/2

12:38 pm-10:17 pm

1 stop7h 39m

Greenville

Tue 9/8

5:28 pm-9:58 pm

1 stop6h 30m

$354

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Wed 9/2

10:11 am-9:50 pm

2 stops9h 39m

Greenville

Tue 9/8

5:28 pm-9:58 pm

1 stop6h 30m

$364

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Wed 1/6

7:00 am-11:19 pm

2 stops14h 19m

Greenville

Sat 1/9

4:15 pm-10:01 pm

1 stop7h 46m

$434

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Wed 1/6

10:45 am-11:19 pm

2 stops10h 34m

Greenville

Sat 1/9

2:54 pm-10:01 pm

2 stops9h 07m

$439
Quickest round-trip

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Thu 8/13

2:08 pm-10:17 pm

1 stop6h 09m

Greenville

Sun 8/16

5:28 pm-9:58 pm

1 stop6h 30m

$459

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Thu 8/13

8:40 am-8:46 pm

2 stops10h 06m

Greenville

Sun 8/16

5:28 pm-9:58 pm

1 stop6h 30m

$469

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Thu 8/13

2:08 pm-10:17 pm

1 stop6h 09m

Greenville

Sun 8/16

5:28 pm-9:58 pm

1 stop6h 30m

$474

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Thu 8/13

10:11 am-9:50 pm

2 stops9h 39m

Greenville

Sun 8/16

7:00 am-11:58 am

1 stop6h 58m

$484

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Thu 8/13

8:40 am-9:50 pm

2 stops11h 10m

Greenville

Sun 8/16

5:30 am-1:38 pm

2 stops10h 08m

$489

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Wed 1/6

7:00 am-3:10 pm

1 stop6h 10m

Greenville

Sat 1/9

4:15 pm-10:01 pm

1 stop7h 46m

$504

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Santa Fe to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santa Fe to Greenville?

United Airlines is the most popular carrier operating from Santa Fe to Greenville

What airlines fly to Greenville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Greenville from Santa Fe according to our data. American Airlines is the first choice among our users, with 49% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 4 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

When to book flights from Santa Fe to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Fe to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Fe to Greenville (SAF to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Fe to Greenville

Fastest flight time

6h 10m

Direct flights

None
The fastest flight from Santa Fe to Greenville takes 6h 10m
There are no direct flights from Santa Fe to Greenville. There are no popular flight routes from Santa Fe to Greenville.
Search flight deals

Frequently asked questions about flying from Santa Fe to Greenville

  • How far is Santa Fe to Greenville by plane?

    Santa Fe and Greenville are 1325.3 mi apart from one another. Typically, this will take 6h 10m by plane in normal conditions.

  • When did momondo last update prices for flights from Santa Fe Airport to Greenville Airport?

    Prices for flights from Santa Fe Airport to Greenville Airport refresh daily.

  • How old do you have to be to fly from Santa Fe Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Fe Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Santa Fe to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santa Fe to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santa Fe to Greenville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Greenville from Santa Fe with this policy.

How can momondo help me find flights from Santa Fe to Greenville?

Once all potential Santa Fe to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Fe to Greenville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Greenville from Santa Fe. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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