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Cheap flights from Santa Ana, California to Missouri from $66

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Missouri departing on 11/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santa Ana, California to Missouri

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
2:20 pm - 9:07 amSNA-STL
16h 47m1 stop
Frontier Logo
7:45 pm - 1:30 pmSTL-SNA
19h 45m1 stop
$109Frontier
Find Deal
Sat, Oct 25 - Mon, Nov 3
Frontier Logo
12:35 pm - 7:32 pmSNA-MCI
4h 57m1 stop
Frontier Logo
8:33 pm - 11:40 amMCI-SNA
17h 07m1 stop
$119Frontier
Find Deal
Thu, Dec 4 - Mon, Dec 15
Delta Logo
12:26 pm - 10:09 pmSNA-SGF
7h 43m1 stop
Delta Logo
6:00 am - 11:16 amSGF-SNA
7h 16m1 stop
$314Delta
Find Deal
Tue, Nov 4 - Sat, Nov 8
American Airlines Logo
11:38 am - 9:26 pmSNA-SGF
7h 48m1 stop
American Airlines Logo
4:18 pm - 8:03 pmSGF-SNA
5h 45m1 stop
$319American Airlines
Find Deal
Fri, Oct 24 - Tue, Oct 28
Southwest Logo
11:55 am - 10:10 pmSNA-STL
8h 15m1 stop
Southwest Logo
2:40 pm - 6:50 pmSTL-SNA
6h 10m1 stop
$323Southwest
Find Deal
Mon, Nov 17 - Wed, Nov 19
Delta Logo
6:45 am - 6:37 pmSNA-STL
9h 52m1 stop
Delta Logo
6:00 am - 1:00 pmSTL-SNA
9h 00m1 stop
$328Delta
Find Deal
Tue, Dec 9 - Thu, Dec 11
United Airlines Logo
1:30 pm - 8:51 pmSNA-SGF
5h 21m1 stop
United Airlines Logo
9:06 am - 1:03 pmSGF-SNA
5h 57m1 stop
$335United Airlines
Find Deal
Tue, Nov 18 - Fri, Nov 28
Southwest Logo
12:45 pm - 12:10 amSNA-STL
9h 25m2 stops
Southwest Logo
2:25 pm - 9:45 pmSTL-SNA
9h 20m2 stops
$343Southwest
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Wed, Oct 29 - Thu, Oct 30
United Airlines Logo
7:00 am - 5:38 pmSNA-JLN
8h 38m1 stop
United Airlines Logo
6:02 pm - 9:45 pmJLN-SNA
5h 43m1 stop
$344United Airlines
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Tue, Mar 3 - Sat, Mar 7
American Airlines Logo
11:38 am - 9:26 pmSNA-SGF
7h 48m1 stop
American Airlines Logo
10:08 am - 3:09 pmSGF-SNA
7h 01m2 stops
$380American Airlines
Find Deal
Fri, Oct 24 - Tue, Oct 28

Alaska Airlines flights from Santa Ana, California to Missouri

Our best Alaska Airlines deals on Santa Ana, California to Missouri flight tickets
Alaska Airlines
Feb 14
SNA12:40 pmSanta Ana J. Wayne/Orange Cnty
9h 16m
1 stop
STL11:56 pmLambert-St Louis
Mar 7
STL7:00 amLambert-St Louis
9h 10m
1 stop
SNA2:10 pmSanta Ana J. Wayne/Orange Cnty
$349
Find similar
Alaska Airlines
Nov 13
SNA12:35 pmSanta Ana J. Wayne/Orange Cnty
9h 24m
1 stop
STL11:59 pmLambert-St Louis
Nov 16
STL4:14 pmLambert-St Louis
8h 16m
1 stop
SNA10:30 pmSanta Ana J. Wayne/Orange Cnty
$354
Find similar
Alaska Airlines
Oct 21
SNA7:00 amSanta Ana J. Wayne/Orange Cnty
7h 22m
1 stop
MCI4:22 pmKansas City
Oct 24
MCI3:28 pmKansas City
8h 12m
1 stop
SNA9:40 pmSanta Ana J. Wayne/Orange Cnty
$527
Find similar

Frontier flights from Santa Ana, California to Missouri

Our best Frontier deals on Santa Ana, California to Missouri flight tickets
Frontier
Oct 25
SNA2:20 pmSanta Ana J. Wayne/Orange Cnty
16h 47m
1 stop
STL9:07 amLambert-St Louis
Nov 3
STL7:45 pmLambert-St Louis
19h 45m
1 stop
SNA1:30 pmSanta Ana J. Wayne/Orange Cnty
$109
Find similar
Frontier
Dec 4
SNA12:35 pmSanta Ana J. Wayne/Orange Cnty
4h 57m
1 stop
MCI7:32 pmKansas City
Dec 15
MCI8:33 pmKansas City
17h 07m
1 stop
SNA11:40 amSanta Ana J. Wayne/Orange Cnty
$119
Find similar
Frontier
Oct 29
SNA2:20 pmSanta Ana J. Wayne/Orange Cnty
16h 47m
1 stop
STL9:07 amLambert-St Louis
Oct 30
STL8:40 pmLambert-St Louis
16h 36m
1 stop
SNA11:16 amSanta Ana J. Wayne/Orange Cnty
$176
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 9, 2025.
Use the filters below to find and compare flights from Santa Ana, California to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Sat 10/25

2:20 pm-9:07 am

1 stop16h 47m

Lambert-St Louis

Mon 11/3

7:45 pm-1:30 pm

1 stop19h 45m

$109

Santa AnaKansas City

SNA - MCI

SNAMCI

Santa Ana J. Wayne/Orange Cnty

Thu 12/4

12:35 pm-7:32 pm

1 stop4h 57m

Kansas City

Mon 12/15

8:33 pm-11:40 am

1 stop17h 07m

$119

Santa AnaSpringfield

SNA - SGF

SNASGF

Santa Ana J. Wayne/Orange Cnty

Tue 11/4

12:26 pm-10:09 pm

1 stop7h 43m

Springfield-Branson

Sat 11/8

6:00 am-11:16 am

1 stop7h 16m

$314

Santa AnaSpringfield

SNA - SGF

SNASGF

Santa Ana J. Wayne/Orange Cnty

Fri 10/24

11:38 am-9:26 pm

1 stop7h 48m

Springfield-Branson

Tue 10/28

4:18 pm-8:03 pm

1 stop5h 45m

$319

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Mon 11/17

11:55 am-10:10 pm

1 stop8h 15m

Lambert-St Louis

Wed 11/19

2:40 pm-6:50 pm

1 stop6h 10m

$323

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 12/9

6:45 am-6:37 pm

1 stop9h 52m

Lambert-St Louis

Thu 12/11

6:00 am-1:00 pm

1 stop9h 00m

$328

Santa AnaSpringfield

SNA - SGF

SNASGF

Santa Ana J. Wayne/Orange Cnty

Tue 11/18

1:30 pm-8:51 pm

1 stop5h 21m

Springfield-Branson

Fri 11/28

9:06 am-1:03 pm

1 stop5h 57m

$335

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Wed 10/29

12:45 pm-12:10 am

2 stops9h 25m

Lambert-St Louis

Thu 10/30

2:25 pm-9:45 pm

2 stops9h 20m

$343

Santa AnaJoplin

SNA - JLN

SNAJLN

Santa Ana J. Wayne/Orange Cnty

Tue 3/3

7:00 am-5:38 pm

1 stop8h 38m

Joplin

Sat 3/7

6:02 pm-9:45 pm

1 stop5h 43m

$344

Santa AnaSpringfield

SNA - SGF

SNASGF

Santa Ana J. Wayne/Orange Cnty

Fri 10/24

11:38 am-9:26 pm

1 stop7h 48m

Springfield-Branson

Tue 10/28

10:08 am-3:09 pm

2 stops7h 01m

$380

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Missouri from

How to get the cheapest flight ticket from Santa Ana, California to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Missouri?

In general, October is the cheapest month to fly from Santa Ana, California to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $362. If you aren’t able to travel to Missouri during the month of October, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $374.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Santa Ana, California to Missouri is on a Tuesday when prices can be found for as low as $396. Flights from Santa Ana, California to Missouri on a Saturday will generally be more expensive and average around $519. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is in the evening. momondo users have found flights departing from Santa Ana, California to Missouri in the evening for as low as $352. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly at noon, with an average ticket price of $456. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

Cheap Santa Ana, California to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Missouri

Direct flights

None
There are no direct flights from Santa Ana, California to Missouri. There are no popular flight routes from Santa Ana, California to Missouri.
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  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Missouri?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Missouri refresh daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Missouri?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Missouri?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to Missouri.

  • What documentation or ID do you need to fly to Missouri?

    The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Santa Ana, California to Missouri

Compare and see reviews for airlines that fly from Santa Ana, California to Missouri with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $103Free CancellationRating
6.3
8,088 reviews
Search Spirit Airlines flights
DeltaPriceFrom $149Free CancellationRating
7.9
7,969 reviews
Search Delta flights
FrontierPriceFrom $150Free CancellationRating
5.8
3,143 reviews
Search Frontier flights
SouthwestPriceFrom $206Free CancellationRating
8.0
4,237 reviews
Search Southwest flights
American AirlinesPriceFrom $268Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights
United AirlinesPriceFrom $288Free CancellationRating
7.4
8,968 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Missouri?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Missouri for you.

Can I find flights from Santa Ana to Missouri with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santa Ana to Missouri flights to just show those with flexible booking policies.

How can momondo help me find flights from Santa Ana to Missouri?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Santa Ana to Missouri.

I’m not ready to book a flight from Santa Ana to Missouri right now. Can momondo alert me if prices change?

Price alerts on flights to Missouri from Santa Ana are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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